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  • hypertension  (2)
  • scanning electron microscope  (2)
  • scanning electron microscope (SEM)  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Plasma adenosine concentrations are elevated in Dahl salt-sensitive rats (1995)
    Springer
    Cellular and molecular life sciences 51 (1995), S. 227-229 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Adenosine ; Dahl salt-sensitive rats ; high-performance liquid chromatography ; hypertension
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract We measured plasma levels of adenosine in Dahl salt-sensitive rats (DS) and Dahl salt-resistant rats (DR) to examine the potential role of adenosine in cardiovascular regulation in this type of hypertension. Plasma adenosine concentrations were significantly higher in DS than in DR. The NaCl content in the diet did not affect plasma adenosine concentration in either DS or DR. Significant positive correlation was found between adenosine concentrations and systolic blood pressure when the data for DS and DR were analyzed together. These results suggest that adenosine may play an important role in the pathophysiology of hypertension in DS.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01931102
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  • 2
    Digitale Medien
    Digitale Medien
    Post-haemorrhagic subarachnoid fibrosis in dogs. Scanning electron microscopic observation and dye perfusion study (1979)
    Springer
    Acta neurochirurgica 46 (1979), S. 105-117 
    Details
    ISSN: 0942-0940
    Schlagwort(e): Subarachnoid haemorrhage ; subarachnoid fibrosis ; scanning electron microscope ; cerebrospinal fluid pathway
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Scanning electron microscopic observations of the subarachnoid space were made in dogs focussing upon the fibre components in both the normal subarachnoid space and in areas of post-haemorrhagic fibrosis. It was concluded that the fibrous tissue originates from the arachnoid membrane itself, while organized haematoma is considered to form a component of the fibrosis. Perfusion of the subarachnoid space of dogs with a solution of 0.1% Toluidine Blue was also done. This showed that cerebrospinal fluid (CSF) is carried from the subarachnoid space directly to the dural sinuses through a fine string-like structure, which is conceivably one of the collateral CSF absorptive pathways.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01407685
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  • 3
    Digitale Medien
    Digitale Medien
    Scanning electron microscopy of the subarachnoid macrophages after subarachnoid haemorrhage, and their possible role in the formation of subarachnoid fibrosis (1979)
    Springer
    Acta neurochirurgica 50 (1979), S. 273-280 
    Details
    ISSN: 0942-0940
    Schlagwort(e): Macrophage ; subarachnoid haemorrhage (SAH) ; subarachnoid fibrosis ; scanning electron microscope (SEM)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Sixty dogs with experimental subarachnoid haemorrhage (SAH), repeated SAH, and subarachnoid fibrosis (examined three weeks and three months after SAH, and treated with urokinase or dexamethasone) were examined by scanning electron microscope (SEM). The authors observed the resting and activated macrophages, the erythrophagocytosis, and giant cells in the subarachnoid space after SAH. They consider that the macrophages play an important role in the formation of subarachnoid fibrosis, similar to the role of macrophages in fibrosis in other sites.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01808524
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  • 4
    Digitale Medien
    Digitale Medien
    Changes in the subarachnoid space after experimental subarachnoid haemorrhage in the dog: Scanning electron microscopic observation (1977)
    Springer
    Acta neurochirurgica 39 (1977), S. 1-14 
    Details
    ISSN: 0942-0940
    Schlagwort(e): Subarachnoid hemorrhage ; hydrocephalus ; subarachnoid fibrosis ; scanning electron microscope
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The possible changes in the subarachnoid space after subarachnoid haemorrhage were studied in animals by using a scanning electron microscope (SEM). About 1 ml/kg of autogenous blood was injected intracisternally in 36 adult mongrel dogs to investigate changes in the subarachnoid space, over periods ranging from immediately after the injection to as long as 6 months. We have come to the conclusion that the injected blood disappears in about one to two weeks; the fibrosis or thickening of the arachnoid membrane appears in one to three weeks, and then returns to normal in a month in instances of rapid recovery, but there are some cases in which fibrosis persists for a long period and becomes chronic. The fact that an increase of fibrous tissue was found in the parietal region, where the injected blood had hardly reached, appears to indicate that the fibrosis is not always limited to the site of the haemorrhage but can occur in remote regions. We also discuss the usefulness of the SEM in the observation of the subarachnoid space, and the finding that vascular specimen preparations can be made by perfusing the brain with 2–10% phosphate-buffered formaldehyde solution.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01405236
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  • 5
    Digitale Medien
    Digitale Medien
    Arachnoid villi affected by subarachnoid pressure and haemorrhage (1979)
    Springer
    Acta neurochirurgica 51 (1979), S. 63-72 
    Details
    ISSN: 0942-0940
    Schlagwort(e): Arachnoid villi ; subarachnoid hemorrhage (SAH) ; increased subarachnoid pressure ; scanning electron microscope (SEM)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The arachnoid villi of 18 dogs were studied. The authors confirmed the pressure gradient changes of the morphology of arachnoid villi of dogs with the scanning electron microscope (SEM). A subarachnoid infusion with 5–10 times higher pressure gradient than the physiological one, tore the superficial endothelial layer from the villi, and the inner part could also be observed stereoscopically. On the surface of the arachnoid villi the authors observed microvilli, openings of vacuoles and intercellular gaps, but did not find openings of preformed channels. After subarachnoid haemorrhage (SAH) generally the villi were blocked but the authors have observed a red blood cell escaping from a villus intercellularly.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01401795
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  • 6
    Digitale Medien
    Digitale Medien
    Renal and hormonal effects of alpha1-adrenoceptor blockade by bunazosin in essential hypertension (1989)
    Springer
    European journal of clinical pharmacology 36 (1989), S. 575-578 
    Details
    ISSN: 1432-1041
    Schlagwort(e): bunazosin ; hypertension ; alpha1-adrenoceptor blocker ; blood pressure ; renal blood flow ; renal function ; renin ; aldosterone ; atrial natriuretic peptide
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary The renal and hormonal effects of the α1-adrenoceptor blocker bunazosin were examined in 6 patients with essential hypertension. Oral bunazosin for 4 to 12 weeks significantly decreased mean blood pressure by 10%, increased effective renal blood flow and creatinine clearance by 34% and 37%, respectively, the plasma norepinephrine concentration was elevated by 60%, and the plasma atrial natriuretic peptide level was lowered by 22%. The plasma renin activity and aldosterone concentration were unchanged. Thus, a moderate reduction in blood pressure was produced by bunazosin treatment while maintaining renal perfusion.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00637738
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