Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-1920
    Keywords: Key words Sarcoma ; meningeal ; Magnetic resonance imaging ; Tumours ; intracranial ; children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Meningeal sarcomas are very rare, highly aggressive tumours affecting children more frequently than adults. The clinical course and MRI of meningeal sarcomas in two cases are discussed with special regard to possible misinterpretation. In one case MRI demonstrated a circumscribed mass in contact with the meninges, with central areas of haemorrhage. In the other, a case of primary leptomeningeal sarcomatosis, several MRI examinations over the course of almost a year were unhelpful, despite severe neurological complaints. Then MRI revealed meningeal contrast enhancement all over the brain and spinal canal, together with cerebral infarcts. MRI of meningeal sarcomas has not been discussed in the literature. MRI did not permit specific diagnosis, but enabled visualisation of the extent of the tumour and/or meningeal involvement. Early histological diagnosis is indispensable for adequate treatment.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-1076
    Keywords: 3-Methylglutaconic aciduria ; 3-Methylglutaconyl-CoA hydratase ; Cardiac hypertrophy ; Complex I ; Cytochrome c oxidase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a 4.5-month-old boy presenting with marked muscular hypotonia in the neonatal period, hepatomegaly, cardiac hypertrophy, recurrent hypoglycemia, metabolic acidosis, and secondary carnitine deficiency, there was a considerable urinary excretion of 3-methylglutaconic and 3-methylglutaric acid. Estimation of 3-methylglutaconyl-CoA hydratase, 3-hydroxy-3-methylglutaryl-CoA lyase and initial enzymatic steps of cholesterol biosynthesis in cultured fibroblasts and in different tissues postmortem revealed no enzyme deficiency. Analyses of the respiratory chain in postmortem tissues demonstrated severe impairment of complex I (NADH ubiquinone oxidoreductase) and complex IV (cytochrome c oxidase) activities in skeletal muscle and reduced complex IV activity in heart.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 143 (1984), S. 160-161 
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 150 (1991), S. 665-668 
    ISSN: 1432-1076
    Keywords: Vitamin D resistant rickets ; Extramedullary haematopoiesis ; Intravenous calcium ; Neutrophil chemotaxis ; Lipid A antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present a new patient with vitamin D dependent rickets type II. A 20-month-old Arabian boy whose parents are first cousins showed florid rickets, myelofibrosis and recurrent septicaemia. In addition to absent specific binding for 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). 25-Hydroxyvitamin D3-24-hydroxylase activity could not be induced in cultured fibroblasts. The patient did not respond to 99 μg 1,25(OH)2D3 per day, but skeletal and haematological abnormalities improved with daily infusion of 100 mg/kg calcium, as serum parathyroid hormone levels fell to normal values. At the age of 7 years, he died from pneumonia. The improvement of haematological abnormalities with calcium infusions but not with 1.25(OH)2D3 suggests a pathogenetic relationship of myelofibrosis and hyperparathyroidism. Having antilipid A IgM antibody titres up to 1∶10.000 after Gram negative septicaemias, the patient never produced corresponding IgG antibodies. His neutrophil chemotaxis was persistently reduced to 57%±3% of age-matched controls (P〈0.028). The patient showed two pathological immune functions considered to contribute to the well-known susceptibility to infection in rickets.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-1076
    Keywords: Aminoacidopathy ; Allo-albuminaemia ; Encephalopathy ; Hartnup syndrome ; Lethality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clinical, biochemical, neuropathological and neurochemical findings in a case of Hartnup syndrome are reported. After initially normal development, the affected girl suffered progressive neuropsychiatric decline with statomotor and mental retardation and intractable seizures and died at the age of 2 years. Postmortem neuropathological and neurochemical investigations showed a combination of extensive neuronal degeneration and cerebral dysmyelination. Pathogenetic hypotheses and the relationship between neuropsychiatric disease and Hartnup syndrome are discussed. Additionally, a fast type bisalbuminaemia present in the girl and her mother is described.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 151 (1992), S. 919-919 
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1432-1076
    Keywords: Cystic fibrosis ; Mutation frequency ; Polymerase chain reaction ; Molecular genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Since the characterization of the gene encoding the cystic fibrosis transmembrane conductance regulator protein and identification of its main mutation, ΔF508, causing cystic fibrosis (CF), more than 150 mutations in this gene have been reported, most of them only in a few or even single CF patients. Attempts to use mutation analysis in genetic counselling or for the diagnosis of CF depends on prevalence data of certain mutations in the respective population, and considerable ethnic differences have been reported. In this study we determined the prevalence of the mutations ΔF508, G551D, R553X, and G542X and of genotypes defined by these mutations in 239 CF patients (444 independent CF chromosomes) seen in our clinic. The analysis for those four mutations alone now permits identification of approximately 75% of all mutations in our CF patients. The complete genotype can be resolved in approximately 63% of patients. This represents the diagnostic sensitivity which can be achieved by mutation analysis in patients without a family history of CF. We conclude that in situations where conventional diagnostic tests are not feasible or difficult to interpret, mutation analysis using a limited set of mutations can contribute significantly to an early and specific diagnosis of CF.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 1 (1945), S. 232-233 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The cleavage mitoses of eggs of the fresh-water oligochete Tubifex may be irreversibly blocked, if treated during a relatively short time by solutions of certain antimitotic substances (benzoquinone, naphthoquinone or colchicine). It is also possible to inhibit tail regeneration in tadpoles of Rana or Xenopus by a single colchicine treatment during only 30 to 60 minutes. It is discussed whether this is due to irreversible loss of regeneration capacity or simply to an inhibition of the first regeneration processes.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European food research and technology 93 (1951), S. 277-286 
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Zusammenfassung Es werden. verschiedene Methoden zur Fettbestimmung in Lebensmitteln hinsichtlich der Ausbeute und der Zusammensetzung der gewonnenen Extrakte überprüft und verglichen. Petroläther oder Äthyläther vermögen die freien Fettsäuren, die Glyceride und das Cholesterin quantitativ zu extrahieren. Vom Lecithin wird dagegen nur ein Teil (62 bis 78%) erfaβt, der Rest verbleibt im Extraktionsrückstand (Restfett) und kann erst durch einen Aufschluβ mit Säure freigelegt werden. — Die Extraktion mit Äther nach vorhergehendem äAufschluβ" mit siedendem Alkohol nach dem Verfahren vonTerrier liefert höhere Lecithinausbeuten (90%), doch verbleiben immer noch 0,6–0,8% Restfett im Extraktionsrückstand. — Noch höhere Ausbeuten an Gesamtlipoiden liefert die Extraktion mit hei\em absolutem Alkohol. Aber auch sie kann noch nicht als quantitativ angesehen werden. Jedoch gelingt es, die Gesamtlipoide durch eine vonGrossfeld vorgeschlagene, von uns modifizierte, warme Extraktion mit einem Gemisch von gleichen Teilen Alkohol und Benzol quantitativ zu isolieren. Der Säureaufschluβ nach der Methode vonBaur undBarschall liefert chemisch verändertes Fett. Wie ein Vergleich der Kennzahlen der Fettkomponenten, des Phosphorsäure- und des Cholesteringehaltes lehrt, wird das Lecithin vollständig in Fettsäuren, Phosphorsäure und Cholin zerlegt und das Cholesterin chemisch verändert, während die Glyceride praktisch nicht angegriffen werden.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European food research and technology 94 (1952), S. 305-309 
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Zusammenfassung Analysen von 3 Hagebuttenmarken des Handels sowie einer selbst hergestellten Zubereitung werden mitgeteilt und beim Vergleich mit den Literaturangaben verschiedene Unstimmigkeiten richtiggestellt. Aus der Bilanz der wasserlöslichen Extraktstoffe ergibt sich, daß Hagebuttenerzeugnisse außer Pektin keine Pflanzenschleime und Verdickungsmittel, keinen Sorbit und keine Citronensäure enthalten.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...