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  • 1
    Digitale Medien
    Digitale Medien
    Effects of leflunomide on glomerulonephritis induced by antibasement membrane antibody in rats (1990)
    Springer
    Inflammation research 31 (1990), S. 321-328 
    Details
    ISSN: 1420-908X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Leflunomide (HWA 486, a novel isoxazol derivative), shown to have potent immunosuppressant and antiinflammatory effects, was evaluated for its inhibitory and therapeutic effects on the glomerulonephritis induced in rats by rabbit antiserum against rat glomerular basement membrane. Leflunomide was administered orally to rats at 0.5 and 2 mg/kg/day for 20 days from 2 days before injection of the rabbit antiserum and at 2 mg/kg/day for 14 days from 5 days after the antibody injection. The present study consisting of 2 experiments for inhibitory (I) and therapeutic (II) effects of leflunomide revealed the following effects at 2 mg/kg: in experiment I, significant decreases in (a) urinary total protein, (b) plasma total cholesterol and fibrinogen and (c) thymus weight, and decreased incidences of fibrin deposits in Bowman's space, adhesion of the glomerulus to Bowman's capsule and deposition of rat IgG and C3; and in experiment II, decreases in (a), (b) and (c), though smaller than in experiment I, and decreases deposition of rat C3. Thus, leflunomide had potent inhibitory and limited therapeutic effects on glomerulonephritis, suggesting that the compound is effective in inhibiting the onset and development of glomerulonephritis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01997627
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  • 2
    Digitale Medien
    Digitale Medien
    Electrophysiological investigation of hemifacial spasm: F-waves of the facial muscles (1996)
    Springer
    Acta neurochirurgica 138 (1996), S. 24-32 
    Details
    ISSN: 0942-0940
    Schlagwort(e): Hemifacial spasm ; F-wave ; lateral spread ; surface electrode
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In patients with hemifacial spasm (HFS), the spasm is due to cross-compression of the facial nerve by a blood vessel. There are currently two hypotheses for the mechanism of HFS: 1) the spasm is caused by ephaptic transmission and an increase in excitability at the site of compression; and 2) the spasm is caused by hyperexcitability in the facial nerve nucleus. In peripheral nerves, F-waves, which result from the backfiring of antidromically activated anterior horn cells, have been proposed as indices of proximal motoneuron conduction and anterior horn cell excitability. Enhancement of the F-waves indicates increased anterior horn cell excitability. We have therefore measured F-waves in the facial muscle of HFS patients in order to investigate the exitability of the facial nerve nucleus. The authors obtained facial nerve evoked responses from 20 HFS patients before microvascular decompression (MVD), 10 HFS patients after MVD and 10 healthy controls. The F-waves, obtained with surface electrodes from the mentalis muscle, were the second response after the M-wave. On the patient's spasm side, the F-wave duration, F/M amplitude ratio and frequency of F-wave appearance significantly increased compared with those of the normal side or healthy controls; minimum latency and chronodispersion did not significantly differ between these groups. In patients whose spasm disappeared completely following MVD, the abnormal muslce response (lateral spread), which is a characteristic sign of HFS, and the enhancement of the F-wave eventually also disappeared. Because of the correlation between HFS and F-waves, the authors' study supports the hypothesis that the cause of HFS is hyperexcitability of the facial motonucleus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01411719
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  • 3
    Digitale Medien
    Digitale Medien
    The closest packing of equal spheres on a spherical surface (1977)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 33 (1977), S. 98-100 
    Details
    ISSN: 1600-5724
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik
    Notizen: A table is given of putative solutions to the Fejes problem: to find the maximum value of the smallest angular distance between any two of N points movable on the surface of a sphere. Values of N run without omission up to 27 with six sporadic cases thereafter. Some applications of this system as a model are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/S0567739477000205
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  • 4
    Digitale Medien
    Digitale Medien
    Tunneling in high-Tc superconductor/semiconductor heterostructure formed on Nb-doped SrtiO"3
    Amsterdam : Elsevier
    Physica B: Physics of Condensed Matter 169 (1991), S. 459-460 
    Details
    ISSN: 0921-4526
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0921-4526(91)90275-J
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  • 5
    Digitale Medien
    Digitale Medien
    Study on electrolyte composition of fluids for renal preservation
    Amsterdam : Elsevier
    Cryobiology 15 (1978), S. 720-721 
    Details
    ISSN: 0011-2240
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/0011-2240(78)90211-0
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  • 6
    Digitale Medien
    Digitale Medien
    High field properties and characteristics of oxide superconductors
    Amsterdam : Elsevier
    Physica B: Physics of Condensed Matter 155 (1989), S. 164-166 
    Details
    ISSN: 0921-4526
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0921-4526(89)90486-9
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  • 7
    Digitale Medien
    Digitale Medien
    Random packing of equal spheres (reply) (1975)
    [s.l.] : Nature Publishing Group
    Nature 256 (1975), S. 522-522 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] GOTOH AND FINNEY REPLY-We are aware of the numerical closeness of 2/n and 0.6366, but until now had no good nonnumerological reason for asserting its significance. We are grateful to Gamba for pointing out the possible use of integral geometry, and will follow up the The average volume of the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/256522a0
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  • 8
    Digitale Medien
    Digitale Medien
    Canopy structure and productivity of Festuca avundinacea Schreb. swards during vegetative and reproductive growth (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 40 (1985), S. 0 
    Details
    ISSN: 1365-2494
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Canopy structure, productivity and their relationships were examined in 2-year-old swards of fourteen tall fescue (Festuca arundinacea Schreb.) strains during the vegetative and reproductive growth stages. During the vegetative growth stage morphological characters, particularly tiller size, were closely associated with productivity. Swards with large tillers showed an effective distribution of the incoming light energy within the canopy and hence low extinction coefficient (K) value and high productivity at complete light interception. On the other hand, although there was no apparent correlation between K and the productivity or the whole crop during the reproductive growth stage, the productivities of the reproductive and vegetative tillers were positively and negatively related to K respectively. Leaf area index of the reproductive tillers and their position in the canopy had marked effects on the distribution of the incoming light energy within the canopy and on the productivity of both types of tillers. The productivity of the vegetative and the reproductive tillers is discussed in terms of the effect of the competition for incoming light energy between both types of tillers.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2494.1985.tb01719.x
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  • 9
    Digitale Medien
    Digitale Medien
    Characterization of some Asian isolates of Phytophthora infestans (2005)
    Oxford, UK : Blackwell Science Ltd
    Plant pathology 54 (2005), S. 0 
    Details
    ISSN: 1365-3059
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: A total of 401 isolates of Phytophthora infestans were collected from eight Asian regions (Korea, India, Taiwan, Indonesia, Thailand, Nepal, China and Japan) between 1992 and 2000 – 318 from potato and 83 from tomato. The isolates were analysed for mating type, metalaxyl resistance, RG57 fingerprinting, mitochondrial DNA (mtDNA) haplotype and the polymorphism of three allozyme loci, i.e. glucose-6-phosphate isomerase (Gpi), peptidase (Pep) and malic enzyme (Me). The isolates were multilocus-genotyped based on RFLP (RG57) fingerprint, dilocus allozyme genotype, mtDNA haplotype and mating type. Twenty multilocus genotypes were identified among 125 isolates. Of these genotypes, 14 had not been previously reported. Some of the multilocus genotypes were common to isolates from several geographical regions, suggesting migration. The metalaxyl-resistant isolates belonged to the multilocus genotypes JP-1, JP-2, and JP-3. Multilocus genotypes coexisting in a single field were found in following regions: Thailand (1994), central China (1996), Nepal (1997) and Japan (1998 and 2000). The possible origins of certain genotypes are discussed, including the possibility of sexual recombination within the P. infestans populations in Nepal and perhaps Thailand.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3059.2005.01286.x
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  • 10
    Digitale Medien
    Digitale Medien
    Electrical properties of Au/ and YBa2Cu3O7−x/SrTi1−yNbyO3 diodes (1991)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 4976-4981 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Electrical properties of Au/ and YBa2Cu3O7−x/SrTi1−yNbyO3 heterojunctions were studied by measuring their capacitance-voltage, current-voltage, and conductance-voltage characteristics. The heterostructures were made by depositing Au or YBa2Cu3O7−x films on SrTi1−yNbyO3 substrates. The results of the capacitance-voltage measurement indicated that there was an interfacial layer having a dielectric constant lower than that of bulk SrTiO3 at the Au/SrTiO3 and YBa2Cu3O7−x/SrTiO3 interfaces. The current-voltage characteristics of the Au/SrTi1−yNbyO3 diodes with substrate Nb concentrations of 0.05 and 0.005 wt. % matched characteristics normally associated Schottky junctions and had a large ideality factor, n, consistent with the low-dielectric-constant interfacial layers. When the carrier concentration of the n-SrTiO3 substrate was 2×1019 cm−3, the Au and YBa2Cu3O7−x junctions showed interfacial-layer tunneling characteristics. The YBa2Cu3O7−x junctions exhibited two peaks in their conductance-voltage relations whose peak structures relies on the superconducting state density in YBa2Cu3O7−x films.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.348999
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