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  • 11
    Electronic Resource
    Electronic Resource
    Transient signals from a buried horizontal magnetic dipole (1973)
    Springer
    Pure and applied geophysics 111 (1973), S. 2264-2272 
    Details
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Summary The impulse response for a horizontal magnetic dipole buried in a conducting half-space is obtained in closed form by an inverse Fourier transform of the known time harmonic solution. Since displacement currents are neglected, the response is not valid for very short times. The waveforms of the magnetic field components at the surface have geometrical dependences which may have application to source location.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00940878
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  • 12
    Electronic Resource
    Electronic Resource
    Growth hormone regulation of DNA replication, but not insulin production, is partly mediated by somatomedin-C/insulin-like growth factor I in isolated pancreatic islets from adult rats (1989)
    Springer
    Diabetologia 32 (1989), S. 191-197 
    Details
    ISSN: 1432-0428
    Keywords: Islets of Langerhans ; B-cell replication ; insulin release ; insulin biosynthesis ; growth hormone ; insulin-like growth factor I ; somatomedin C
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have investigated whether the previously demonstrated stimulatory actions of growth hormone on DNA synthesis and (pro)insulin biosynthesis and release of isolated adult rat islets of Langerhans are mediated by an autocrine release of somatomedin-C/insulin-like growth factor I (SM-C/IGF I). In medium containing 1% fetal calf serum, the presence of 16.7 mmol/l glucose, or 2.7 mmol/l glucose supplemented with a concentrate of essential amino acids, caused a significant increase in 3H-thymidine incorporation and insulin release compared to 2.7 mmol/l glucose alone but no increase in SM-C/IGFI release. Further supplementation with 1 μg/ml growth hormone increased 3H-thymidine incorporation and SM-C/IGF I release within all groups, and insulin release in the 16.7 mmol/l glucose and 2.7 mmol/l plus amino acid groups. The ability of growth hormone to increase 3H-thymidine incorporation in the presence of 16.7 mmol/l glucose, but not its action on insulin release, was partly inhibited by a monoclonal antibody against SM-C/IGF I (control cultures 100%; growth hormone alone 261±27%, mean±SEM; growth hormone+anti-SM-C/IGFI 179±21%; p〈0.05, n=18). Growth hormone, but not 100 ng/ml SM-C/IGF I, increased insulin biosynthesis assessed as immunoprecipitable 3H-labelled insulin by 45%, but this was accompanied by a similar increase in overall protein synthesis. Similarly growth hormone, but not SM-C/IGF I caused a 75% increase in glucose oxidation by islets. Both growth hormone and SM-C/IGF I failed to increase the cellular uptake of α-aminoisobutyric acid or 3-O-methyl glucose over a 90 min period. The results suggest that while the stimulatory effect of growth hormone on islet cell insulin biosynthesis and release, glucose oxidation and general protein synthesis is probably direct, its action on B-cell replication is partly mediated by a paracrine release of SM-C/IGF I. This may provide a mechanism for increasing B-cell mass and consequently total insulin output during times of increased metabolic demands on insulin secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00265093
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  • 13
    Electronic Resource
    Electronic Resource
    British Diabetic Association Abstracts (1968)
    Springer
    Diabetologia 4 (1968), S. 174-180 
    Details
    ISSN: 1432-0428
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01219441
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  • 14
    Electronic Resource
    Electronic Resource
    Raised plasma somatomedin activity and cartilage metabolic activity (35S sulphate uptake in vitro) in the fetus of the mildly diabetic pregnant rat (1982)
    Springer
    Diabetologia 23 (1982), S. 270-274 
    Details
    ISSN: 1432-0428
    Keywords: Rat fetus ; streptozotocin ; insulin ; pancreas ; somatomedin ; growth ; cartilage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A mildly diabetic state was induced in pregnant rats following treatment with streptozotocin the day after mating. On day 21 of gestation, these rats had a lower plasma insulin (55±9 versus 107±23 mU/l for control rats; p〈0.05, mean ±SEM) and a reduced pancreatic area occupied by insulincontaining cells compared with control animals (0.40±0.04 versus 1.03±0.08%; p〈0.001), but hyperglycaemia was not apparent. Fetuses from mildly diabetic animals were longer but not heavier than those from control rats. Plasma somatomedin activity measured by fetal rat cartilage bioassay was higher in fetuses from mildly diabetic rats (1.12±0.07 versus: 0.74±0.05 U/ml for control fetuses; p〈0.001) as was cartilage metabolic activity in basal culture medium (35S sulphate uptake) (1 883±141 versus 1473±104 c.p.m./mg for control rats; p〈0.05), but plasma insulin levels and the pancreatic area occupied by insulin-containing cells did not differ between the two groups of fetuses. Fetal plasma somatomedin activity, measured by fetal cartilage assay, showed a significant positive correlation with both body weight and length. It is concluded that by day 21 of gestation a small body overgrowth had occurred in the fetus of the mildly diabetic rat and this was associated with an increase in plasma somatomedin activity, but not with any abnormality of circulating insulin levels or volume density of B cells in the pancreatic islets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252854
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  • 15
    Electronic Resource
    Electronic Resource
    Land subsidence along the northeastern Texas Gulf coast: Effects of deep hydrocarbon production (1995)
    Springer
    Environmental geology 25 (1995), S. 181-191 
    Details
    ISSN: 1432-0495
    Keywords: Subsidence ; Eustatic sea level rise ; Relative sea level rise ; Coastal erosion ; Deep hydrocarbon production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The Texas Gulf of Mexico coast is experiencing high (5–11 mm/yr) rates of relative sea level (RSL) rise that are the sum of subsidence and eustatic sea level (ESL) rise. Even higher rates are associated with areas of groundwater pumping from confined aquifers. We investigate the possibility of deep petroleum production as a cause for the high regional rates of subsidence. The northeast Texas coast was chosen for the study because it has a high rate of RSL rise, very limited groundwater production, and a long history of petroleum production. We examine in detail the Big Hill and Fannett fields, for which adequate bottom hole pressure (BHP) and well log data are available. The hypothesis of deep petroleum production is tested in three ways. First, industry BHP tests show many of the fields are depressurized to far below hydrostatic pressures. Second, analysis of BHP data over time in the Big Hill and Fannett fields indicates that some Zones in these fields were below hydrostatic when production commenced. This indicates that depressurization from production in neighboring fields or zones within the same field is not limited to the production zone. Third, three models for subsidence (a general 1-D regional model, an intrareservoir model, and a reservoir bounding layer model), using reasonable hydrogeological parameters, predict subsidence within the inferred range of data. The latter two models use data from the Big Hill and Fannett fields. Additional verification of the hypothesis that deep petroleum production is causing or accelerating regional subsidence will require the collection and analysis of data on the subsurface hydrogeological parameters and detailed measurements of the spatial and temporal distribution of subsidence along the Texas Coast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00768547
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  • 16
    Electronic Resource
    Electronic Resource
    Stereoscopic particle image velocimetry measurements of the flow around a Rushton turbine (2000)
    Springer
    Experiments in fluids 29 (2000), S. 478-485 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  The principles of stereoscopic particle image velocimetry (PIV), including distortion compensation, were applied to the turbulent flow in a vessel stirred by a Rushton turbine. An angular offset configuration was used and tilt-axis lens mounts were incorporated in order to satisfy the Scheimpflug condition, significantly reducing the ordinarily large depth of field requirements of such configurations. A distortion compensation procedure, or in situ calibration, was utilized in place of the ray tracing, or mechanical registration, used in previous studies. The calibration procedure was validated using two tests, one a rigid translation of a speckle target, the other the viscous flow between two concentric cylinders. The results of the tests suggest the success with which the distortion compensation procedure may be applied to real fluid flows. Phase-locked instantaneous data were ensemble averaged and interpolated in order to obtain mean 3-D velocity fields on a cylindrical shell enclosing the turbine blade. From these fields, the tip vortex pairs and the radial jet documented in previous studies of mixer flows were easily identified.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003480000116
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  • 17
    Electronic Resource
    Electronic Resource
    Thrombopenische Purpura nach Gebrauch von Sedormid (1939)
    Springer
    Archives of toxicology 10 (1939), S. A49 
    Details
    ISSN: 1432-0738
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02452419
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  • 18
    Electronic Resource
    Electronic Resource
    Impedance of an electric dipole located in a cylindrical cavity in a dissipative medium (1976)
    Springer
    Applied physics 11 (1976), S. 351-356 
    Details
    ISSN: 1432-0630
    Keywords: 84
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The electromagnetic fields of an electric dipole located inside a cylindrical cavity or empty tunnel are formulated. The results are used to deduce an expression for the change of self-impedance due to the presence of the cavity or tunnel walls. A numerical evaluation of the resultant convergent integral and a summation of the angular harmonic series were performed. An important finding is that the input resistance of the dipole is approximately a constant for frequencies less than about 25 MHz for a typical tunnel radius of 2 m. Such results are shown to be in qualitative agreement with an earlier analysis of an electric dipole over a dissipative half-space.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00919363
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  • 19
    Electronic Resource
    Electronic Resource
    Interaction between endocrine and paracrine peptides in prenatal growth control (1987)
    Springer
    European journal of pediatrics 146 (1987), S. 113-122 
    Details
    ISSN: 1432-1076
    Keywords: Prenatal growth ; Nutrition ; Insulin ; Placental lactogen ; Tissue growth factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The evidence reviewed here shows that the endocrinology of fetal growth is very different from that operating postnatally. Pituitary hormones play little part in stimulating growth of the lean body mass or skeleton although growth hormone (GH) may be involved, in some as yet ill defined way in the ontogeny of the fetal pancreatic islet and insulin secretion. Insulin is important because it stimulates fetal cellular anabolism but acts in a permissive manner: with too little insulin growth is inhibited, with too much growth proceeds at a genetically predetermined rate. Placental lactogen (PL), or other peptides within the GH/PL family, may act as a true growth-promoting hormone in the fetus; it stimulates both cellular metabolism and mitosis. The part played by endocrine control mechanisms in the fetus is set in context by an appreciation of the importance of locally acting tissue growth factors, and in particular the somatomedins. Their part in fetal growth control is intimately bound up with the plane of nutrition experienced by the fetus. It is concluded that the simplest analysis that makes biological sense involves a consideration of hormones, tissue growth factors and nutrition, not hierarchically but as mutually interacting variables.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02343214
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  • 20
    Electronic Resource
    Electronic Resource
    Electromagnetic field focusing (EFF) probe in aneurysm thrombosis (1986)
    Springer
    Acta neurochirurgica 81 (1986), S. 68-71 
    Details
    ISSN: 0942-0940
    Keywords: Electromagnetic field ; radiofrequency probe ; aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Due to its capability of producing a well localized intense heat field of predictable dimensions, the electromagnetic field focusing probe was evaluated experimentally as a surgical tool in aneurysm thrombosis. Aneurysm models were created by anastomosing a segment of vein to the abdominal aorta. Seventy-five such aneurysms were created in seventy-five animals. The aneurysms were then placed under the solenoidal radiofrequency coil and the tip of the field focusing probe was inserted into them. Intense heat was delivered with well defined, effective and quick thrombosis and shrinkage of the aneurysm. Nineteen of the aneurysms were followed for up to one week. Histological studies were conducted showing complete thrombosis of the aneurysm with good preservation of the aorta. With further refinement of this technique, it is hoped that stereotaxic aneurysm thrombosis might be possible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01456267
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