Library

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1985-1989
  • 1970-1974  (2,405)
  • 1972  (2,405)
  • Polymer and Materials Science  (2,332)
  • Rat  (73)
  • 1
    ISSN: 1432-2013
    Keywords: Diphosphate ; Rat ; Vitamin D Metabolism ; Intestinal Calcium ; Absorption ; Bone Mineralization ; Renal Functions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The metabolism and the organ distribution of double labelled vitamin D3 (1,2-3H-4-14C-cholecalciferol) has been studied in rats in which the bone mineralization and the intestinal calcium absorption have been inhibited by a large pose (10 mg P/kg s.c. for 7–14 days) of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP). The most striking difference found was a reduced accumulation of radioactive cholecalciferol and its metabolites in the kidney of EHDP-treated rats. It is unlikely that this effect was due to an unspecific alteration of the functional renal tissue since blood urea, glomerular filtration rate and renal plasm a flow remained unaltered by this dose of EHDP. The EHDP-treated rats were able to form the metabolite eluted with peak IV of the silicic acid chromatographic system, that is 25-hydroxycholecalciferol. In these vitamin D repleted rats fed a high calcium diet, the tritium deficient metabolite eluted with peak V (1,25-dihydroxycholecalciferol) was only found in the intestinal mucosa of both control and EHDP groups three days after the injection of radioactive cholecalciferol, and this in a very small amount. Therefore no definitive conclusion can be drawn as to a possible interference of EHDP treatment on the production of 1,25-dihydroxycholecalciferol. The change in the renal metabolism of vitamin D in rats treated with a rachitogenic dose of EHDP may be caused by the modifications of the calcium metabolism brought about by the diphosphonate. Its relation, if any, with the decreased calcium absorption remains to be established.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 272 (1972), S. 369-377 
    ISSN: 1432-1912
    Keywords: Trimethoprim ; Placental Transfer ; Distribution ; Elimination ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary After a single i.v. administration of 50 mg/kg of Trimethoprim (TM) to rats in late pregnancy, a diffusion equilibrium of the folic acid inhibitor in the foetal organs is reached after 30–60 min. The TM levels in maternal as well as in foetal organs can have an inhibitory effect on folic acid reductase activity. The elimination of TM is lower in pregnant than in non-pregnant animals. The TM elimination of the foeti is dependent on the elimination capacity of the mother. Three-days-old rats eliminate TM some four times slower than mature animals owing to their reduced kidney development.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 272 (1972), S. 417-436 
    ISSN: 1432-1912
    Keywords: Intestinal Blood Flow ; Instestinal Absorption ; Tritiated Water-Solvent Drag ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Jejunal loops of anaesthetized rats were perfused with hypo-, iso-, and hypertonic buffered solutions containing tritiated water. The blood flow, the disapperance rate (from the intestinal lumen), and the appearance rate (in the intestinal venous blood) were determined simultaneously. 2. A decrease of the blood flow from about 1.7 to 0.2 ml min−1g−1 wet tissue weight diminished the appearance and disappearance rate of tritiated water. An increase of the blood flow caused the reversed results. The appearance rate was almost completely determined by the blood flow indicating that the intestinal absorption of tritiated water is blood flow limited. Therefore the absorption rate of tritiated water characterizes badly the diffusive water permeability of the intestinal epithelium. 3. A water net flux directed towards the blood accelerated and towards the intestinal lumen retarded the intestinal absorption of tritiated water at low, intermediate, and high blood flow values. 4. The data were analysed by a modified four-compartment-model considering the variation of blood flow and water net flux. The water net flux influences the absorption of tritiated water during the penetration through the epithelium by solvent drag (sieving coefficient 1-σ=1.54±0.19) as well as by changing the blood flow rate through capillaries near the epithelium.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 274 (1972), S. 357-374 
    ISSN: 1432-1912
    Keywords: Intestinal Blood Flow ; Blood-to-Lumen Flux ; Tritiated Water ; Solvent Drag ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Anaesthetized rats were loaded with tritiated water and a jejunal loop was perfused with hypo-, iso-, and hypertonic buffered saline solutions. The blood flow, the disappearance rate (from the blood), and the appearance rate (in the intestinal lumen) were determined simultaneously. 2. A decrease of the blood flow from about 1.7 to 0.2 ml min−1g−1 wet tissue weight diminished both the appearance rate and the disappearance rate of tritiated water. An increase of the blood flow caused the reversed results; however, at high blood flow the appearance and disappearance rate did not reach the value measured in the experiments with decreasing blood flow. 3. A water net flux directed towards the blood retarded and towards the intestinal lumen accelerated the blood-to-lumen flux of tritiated water at low, intermediate, and high blood flow values. 4. The data were analysed by a modified four-compartment-model considering the variation of blood flow and water net flux. The water net flux influences the blood-to-lumen flux of tritiated water by solvent drag during the penetration through the epithelium and by changing the luminal concentration (e.g. dilution) as well as the blood flow rate in the capillaries near the epithelium.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 273 (1972), S. 352-365 
    ISSN: 1432-1912
    Keywords: Calcium Transport ; Small Intestine ; Rat ; in vitro ; in vivo
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intestinal calcium (Ca) transport was studied in the rat jejunum by the in vitro perfusion technique of Fisher and Parsons and in the tied loop in vivo. Mucosal uptake and absorption of Ca was examined under the following conditions: rising intraluminal Ca-concentrations (0.5–128 meq/l); inhibition of energy dependent metabolism (2,4-dinitrophenol, N2, low temperature); net water flow, out of or into the intestinal lumen; addition of strontium (Sr); pretreatment with low Ca-diet and with 6-methyl-prednisolone. The concentration-dependent Ca absorption curve rose steeply at low Ca-concentrations but changed to a slowly rising straight line above 16 meq/l Ca++. In contrast, Ca uptake into the intestinal wall was directly related to Ca concentration, was linear from the beginning and paralleled the straight part of the absorption curve. Ca absorption was decreased by inhibition of energy dependent metabolism, addition of Sr and pretreatment with prednisolone. Pretreatment with low Ca diet increased Ca absorption and direction of net water flow (“solvent drag”) had no effect on it. Mucosal uptake of Ca was similar to Ca absorption except that metabolic inhibition increased Ca uptake but decreased Ca absorption. These results are compatible with the concept of a passive mucosal uptake and of an active absorption of Ca at low intraluminal Ca concentrations with additional passive component at high Ca concentrations.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 274 (1972), S. 91-106 
    ISSN: 1432-1912
    Keywords: Choline ; Blood-Brain-Barrier ; Brain ; Rat ; Lecithin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the rat brain the concentration of choline increases with a velocity of 20.5 nMol/g×min immediately after decapitation. This is not due to postmortal disintegration of the tissue but to persisting biochemical reactions in the absence of blood flow. This rise of choline must be considered if the concentration of choline in the living animal is to be established. Taking this fact into account one arrives at a value of 27.5±1.7 nMol Choline/g wet weight. From the arterio-venous difference of choline concentrations it has been postulated that there is an efflux of 7.2±1.5 nMol/g×min from the brain into the blood. After i.v. injection of labelled choline the peak of the specific radioactivity of choline in the brain is reached in less than 1 min but amounts to only one tenth of the specific activity of choline in blood-plasma. The specific activities in both compartments decline in parallel. Thus it can be concluded a) that choline penetrates easily through the blood-brain barrier, but the concentration gradient is directed from brain to blood; and b) that choline is continuously formed in the brain, which process permanently dilutes the quantity of labelled choline and prevents the specific activities in blood and brain from becoming equal. The calculations of turnover-rates in the different reactions leading to the choline containing glycerophosphatides are based on the data obtained. On the basis of these findings it is proposed that in the brain phosphorylated derivatives of ethanolamine (phosphorylethanolamine, cytidinediphosphate-ethanolamine) can be methylated to form the respective choline derivatives.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 10 (1972), S. 238-251 
    ISSN: 1432-0827
    Keywords: Growth ; Bone ; Rat ; Tetracycline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé La vitesse de croissance normale en longueur de la métaphyse proximale du tibia est déterminée chez le rat Sprague-Dawley entre les âges de 20 et 100 jours, en utilisant la méthode à la tétracycline. Le taux de croissance ne varie que légèrement dans les groupes d'âges différents. Il est plus élevé chez les animaux jeunes et décroit considérablement en fonction de l'augmentation de l'âge. Les rats mâles présentent une croissance plus élevée que les femelles. Cette étude a pour but de mettre au point une méthode permettant de déterminer les facteurs expérimentaux, liés à la croissance en longueur du rat.
    Abstract: Zusammenfassung Die normale Längenwachstums-Geschwindigkeit der proximalen Wachstumsplatte der Tibia wurde bei Sprague-Dawley-Ratten in einem Alter zwischen 20 und 100 Tagen mittels der Tetracyclinmethode gemessen. Die Wachstumsgeschwindigkeit variierte nur wenig innerhalb der einzelnen Altersgruppen. Die Geschwindigkeit war bei jungen Tieren am höchsten und nahm mit zunehmendem Alter beträchtlich ab. Männliche Ratten wuchsen schneller als weibliche. Diese Arbeit dient als Grundlage, um die experimentelle Beeinflussung des Längenwachstums der Ratte abschätzen zu können.
    Notes: Abstract The rate of normal growth in length from the proximal growth plate of the tibia in the Sprague-Dawley rat was measured between 20 and 100 days of age using the tetracycline method. The growth rate varied only slightly within different age groups. The rate was highest in young animals and decreased considerably with increasing age. Male rats grew faster than female. This study is intended to provide a base for an evaluation of experimental influence on the growth in length of the rat.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 30 (1972), S. 29-38 
    ISSN: 1432-0738
    Keywords: Dichlorvos ; Teratology ; Inhalation ; Rat ; Rabbit ; Dichlorvos ; Teratologie ; Inhalation ; Ratte ; Kaninchen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An Kaninchen und Ratten wurde die teratogene Wirkung von inhaliertem Dichlorvos untersucht. Im Versuch waren primipare Kaninchenweibchen der Rasse “Dutch” mit einem Anfangsgewicht von 2 bis 3 kg und primipare Rattenweibchen vom Stamm “Carworth Farm E“ mit einem Anfangsgewicht von 200 bis 300 g. Die Tiere wurden während der gesamten Trächtigkeit folgenden Konzentrationen in der Atemluft ausgesetzt: 0,25, 1,25 und 6,25 μg Dichlorvos pro Liter Luft. Ein zusätzliches Experiment am Kaninchen wurde mit 2 und 4 μg Dichlorvos pro Liter Luft durchgeführt. Die Behandlung wirkte weder beim Kaninchen noch bei der Ratte teratogen. Selbst Konzentrationen, die für die Kaninchen tödlich waren, und die eine deutliche Cholinesterasehemmung in Plasma, Erythrocyten und Gehirn der Ratten und Kaninchen hervorriefen, wurden ohne Schädigung für die Feten vertragen.
    Notes: Abstract The teratogenic potential of inhaled dichlorvos vapour for rabbits and rats was investigated on the offspring of primiparous female Dutch rabbits weighing 2 to 3 kg and primiparous female Carworth E strain rats weighing 200 to 300 g. The animals were exposed throughout pregnancy at concentrations of 0.25, 1.25 and 6.25 μg dichlorvos per litre of air. In an additional experiment pregnant rabbits were exposed to concentrations of 2 and 4 μg dichlorvos per litre of air. The results gave no indication that dichlorvos vapour is teratogenic in rabbits or rats even at exposure concentrations resulting in maternal deaths in rabbits, and causing depression of plasma, erythrocyte and brain cholinesterase activities in pregnant animals of both species.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 30 (1972), S. 9-18 
    ISSN: 1432-0738
    Keywords: 2,2-Dichlorvinyl Dimethyl Phosphate ; Dichlorvos ; Vapona ; Metabolism ; Man ; Rat ; Mouse ; Hamster ; 2,2-Dichlorvinyl-dimethylphosphat ; Dichlorvos ; Vapona® ; Stoffwechsel ; Mensch ; Ratte ; Maus ; Hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An Mäusen und Hamstern wurde die Exkretion und Retention der Radioaktivität nach Fütterung mit [1-14C-Vinyl]-Dichlorvos bestimmt. Außerdem wurde beim Menschen die Exkretion und Exhalation gemessen und die erhaltenen Werte mit den tierexperimentellen Daten von Rattenversuchen verglichen. Die Ergebnisse zeigen einen schnellen Stoffwechsel von Dichlorvos bei allen vier untersuchten Species. Die Dealkylierung zu Desmethyldichlorvos spielt bei der Biotransformation eine untergeordnete Rolle. Eine gewisse Ausnahme zeigen die Mäuse, bei denen 18,5 % der zugeführten Radioaktivität als Desmethyldichlorvos aufgefunden werden konnte. Bei allen Species kam es zu einer hydrolytischen Spaltung zu Dichloracetaldehyd, der weiter zu Dichloraetbanol reduziert wird. Der weitere Weg führt über die Ausscheidung als Glucuronid mit dem Harn. Ein Teil wird dechloriert und das14C-Atom als14CO2 oder14C-Hippursäure im Harn ausgeschieden. Im menschlichen Harn konnte Dichloraethanol nach Inkubation mitβ-Glucuronidase nachgewiesen werden, wenn hohe Dichlorvoskonzentrationen (38 μg/l) eingeatmet wurden. Auf dieser Basis könnte eine Überwachungsmethode gegen die Inhalation von zu hohen Dichlorvoskonzentrationen ausgearbeitet werden.
    Notes: Abstract The routes of excretion and retention of radioactivity following the ingestion of [1-14C-vinyl]dichlorvos by mice and hamsters have been determined. The excretion of radioactivity in urine and exhaled air of man has also been measured. The data have been compared with those for rats. The results indicate that metabolism is rapid in the four species. Dealkylation to desmethyldichlorvos is a minor route of biotransformation, except in the mouse, where desmethyldichlorvos constitutes at least 18.5 % of the administered radioactivity. Hydrolytic metabolism of dichlorvos occurs in all species and leads presumably to dichloroacetaldehyde which is further metabolized by (i) reduction to dichloroethanol and excretion in the urine as the glucuronide and (ii) dechlorination followed by incorporation of the carbon atoms into endogenous biosyntheses and excretion as [14C]carbon dioxide and [14C]hippuric acid in the urine. Dichloroethanol can be detected inβ-glucuronidase-treated urine after exposure of a human subject to high air concentrations (38 μg/l) of non-radioactive dichlorvos. This may form the basis of a method of monitoring the exposure of humans to high concentrations of dichlorvos.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 28 (1972), S. 39-45 
    ISSN: 1432-0738
    Keywords: Ferrihexacyanoferrate (II) ; Rat ; Thallium ; Toxicity ; Metabolism ; Ferrihexacyanoferrat(II) ; Ratte ; Thllium ; Toxicität ; Stoffwechsel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Verabfolgung einer 2% igen kolloidalen Lösung von Ferrihexacyanoferrat (II) (FHCF) als Trinkwasser erhöht bei der Ratte die Ausscheidungsrate von intravenös injiziertem Tl2SO4 (mit 204Tl markiert) aus Leber, Nieren und Muskulatur auf das 2,8fache. Dieser Effekt ist zeitunabhängig. Die LD 50/30 d von intravenös injiziertem Tl2SO4 wird durch FHCF-Behandlung um das 2,3fache erhöht. Für diesen Schutzeffekt ist allerdings nur das während der ersten 24 Std verabfolgte FHCF verantwortlich. Diese Befunde weisen darauf hin, daß die Schäden bei der akuten Tl-Intoxikation sehr schnell irreversibel werden.
    Notes: Abstract The administration of a 2% colloidal solution of ferrihexacyano ferrate (II) (FHCF) as drinking water increases in the rat the excretion of intravenously injected Tl2SO4 (labelled by 204Tl) from liver, kidneys and muscles by a factor of 2.8. This effect is independant of time. FHCF-treatment increases the LD 50/30 d of intravenously injected Tl2SO4 by a factor of 2.3. This protection, however, is provided by FHCF only if administered during the first 24 hours. These findings suggest that the damage resulting from acute Tl-intoxication quickly becomes irreversible.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 11
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 137 (1972), S. 301-316 
    ISSN: 1432-0568
    Keywords: Monoamines ; Brain ; Ontogeny ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The early ontogeny of the monoamine neuron systems in the rat brain has been analysed using Falck-Hillarp fluorescence histochemistry. Serial sagittal sections of embryos with a crown rump length between 7 and 13 mm, approximately corresponding to gestational days 12 to 15 were obtained from mothers treated with a monoamine oxidase inhibitor given in order to increase the monoamine levels of the embryos. 5-hydroxytryptamine (5-HT)-neurons made their first appearance in the 8 mm embryo, dopamine (DA)-neurons in the 9 mm embryo, and noradrenaline (NA)-neurons in the 11 mm embryo. Small, rounded, weakly fluorescent cell bodies forming sparse aggregations appeared first. Fluorescent processes of two types soon appeared. Short processes from the cell bodies were running perpendicular to the long axis of the brain stem within the cell groups, while long slender axon bundles could be traced ascending through the met- and mesencephalon and into the prosencephalon as well as descending in the myelencephalon andspinal cord. In the 12 mm embryo the primordial DA cell formation of the substantia nigra with its striatal projections, the 5-HT neuron formations of the caudal mesencephalon, met- and myelencephalon as well as the NA neurons of the met- and myelencephalon are relatively well developed. It is concluded that the monoamine-neurons develop mechanisms for synthesis and storage of amines at a very early stage during ontogeny, thus recapitulating the phylogeny of these old systems. Likewise, monoamine oxidase is present early. The presence of neurotransmitters specifying the different developing neurons long before development of their nerve terminal areas and therefore before the establishment of normal synaptic function may indicate a role of these substances during ontogeny other than transmission of nerve impulses.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 12
    ISSN: 1432-0568
    Keywords: Rat ; Cold ; Pineal gland ; Synaptic vesicles ; Zinc iodide-osmium tetroxide (ZIO) reaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In den synaptischen Bläschen der Nervenendigungen der Epiphyse von Ratten, welche 2 und 4 Tage einer Temperatur von −6° bis −8°C ausgesetzt worden waren, hat man eine signifikante Vermehrung des Zinkjodid-Osmiumtetroxyd (ZIO) reaktiven Materials festgestellt. Der durchschnittliche Durchmesser der ZIO-positiven synaptischen Vesiculae betrug bei den Kontrollratten 234 Å und bei den Ratten, welche 2 und 4 Tage unter der Kälte gelebt hatten, 380 Å, bzw. 379 Å. Die ZIO-Reaktion war bei den Kontrollratten in 49,3% der synaptischen Vesiculae positiv, nach zweitägiger Kälteeinwirkung waren 58,7% und nach viertägiger Kälteeinwirkung 72,1% der synaptischen Vesiculae ZIO-positiv. Auf Grund der vorliegenden Arbeit war es jedoch nicht möglich zu entscheiden, ob die Vermehrung des ZIO-reaktiven Materials mit einer gleichzeitigen Zunahme der biogenen Amine verbunden ist.
    Notes: Summary In the synaptic vesicles of pineal nerve endings of Wistar rats exposed for 2 and 4 days to a temperature of −6° to −8° C, a significant increase of the zinc iodide-osmium tetroxide (ZIO) reactive material was observed. The mean diameter of ZIO reactive synaptic vesicles of control rats was 234 Å; in rats exposed to cold for 2 and 4 days it was 380 Å, respectively 379 Å. In control rats the ZIO reaction was positive in 49,3% of the synaptic vesicles. The reactivity increased to 58,7% in rats exposed to cold for 2 days, and to 72,1% in rats exposed to cold for 4 days. However, the results of the present study do not permit to conclude if an increase of ZIO reactive material is accompanied by a simultaneuos increase of biogenic amines.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 137 (1972), S. 1-29 
    ISSN: 1432-0568
    Keywords: Corticotropin-Releasing Factor ; Median eminence ; Rat ; Histology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der Zona externa infundibuli der normalen Ratte kommen geringe Mengen „Gomori-positiver” Granula vor. Nach bilateraler Adrenalektomie erfolgt eine Vermehrung der Granula, die sich durch Gabe von Hydrocortison einschränken oder verhindern läßt. Dieser Befund hat zu der Annahme geführt, daß die Granula das morphologische Äquivalent des Corticotropin-releasing factor (CRF) darstellen. Morphometrische Untersuchungen an 160 weiblichen Wistarratten zeigen, daß die Menge der nach bilateraler Adrenalektomie in der Zona externa infundibuli nachweisbaren „Gomori-positive” Granula von der postoperative Überlebensdauer abhängt. Die Granulamenge nimmt zunächst bis zum 14. Tag p.o. zu und fällt dann wieder ab. Substitution bilateral adrenalektomierter Ratten mit Hydrocortisonacetat-Kristallsuspension bewirkt eine dosisabhängige Verminderung der Granulamenge, wenn die Behandlung am Operationstag begonnen wird. Applikation von Hydrocortisonacetat-Kristallsuspension vom 14.–21. Tag p.o. führt dagegen zu einer gesteigerten Granulavermehrung. Auch bei stärkster Vermehrung sind die Granula stets nur im Infundibulum und nicht in anderen Bereichen des Hypothalamus nachweisbar. Sie besitzen bei bilateral adrenalektomierten Tieren ein charakteristisches Verteilungsmuster mit besonders hohen Konzentrationen in den paramedianen Abschnitten des rostralen Infundibulumdrittels. Aus der Art und Weise ihrer Verteilung ist zu vermuten, daß die Granula 2 Nervenfaserzügen angehören und ein Neurosekret darstellen. Nach den vorliegenden Untersuchungen besteht zwischen dem Verhalten der „Gomori-positiven” Granula in der Zona externa infundibuli und dem aus pharmakologischen Untersuchungen bekannten Verhalten des Corticotropin-releasing factor eine weitgehende Parallelität. Sie legt nahe, die Menge der Granula als Parameter der CRF-Aktivität zu verwenden.
    Notes: Summary In the zona externa infundibuli (outer layer of the median eminence) of the normal rat a minute number of “Gomori-positive” granules can be detected. Following bilateral adrenalectomy their number increases. This augmentation can be restricted or inhibited by administration of hydrocortisone, a finding, which has led to the assumption that the granules are the morphological equivalent of the corticotropin-releasing factor (CRF). Morphometrical studies on 160 female Wistar rats show that following bilateral adrenalectomy the quantity of “Gomori-positive” granules is dependent on the length of the post-operative survival period. Up to the 14th day p.o. the quantity of granules increases; from then on it diminishes. Substitution of bilaterally adrenalectomized rats with hydrocortisone acetate crystal suspension results in a dose-dependent decrease in the quantity of granules if treatment is begun on the day of operation. In contrast, administration of hydrocortisone acetate crystal suspension from the 14th to the 21st day p.o. results in increased augmentation of the granules. Even when maximum augmentation of the granules is reached, they are invariably found only in the infundibulum and not in other regions of the hypothalamus. In animals that have been subjected to bilateral adrenalectomy, the granules show a characteristic pattern of distribution, with particularly high concentrations in the paramedian parts of the rostral third of the infundibulum. The manner in which the granules are distributed suggests that they are a neurosecretory substance localized in two fibre tracts. The present study points to a close parallelism between the behaviour of the “Gomori-positive” granules in the zona externa infundibuli and that of the corticotropin-releasing factor as revealed by pharmacological investigations. It would seem that the quantity of granules can be used as a parameter of CRF activity.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 138 (1972), S. 155-165 
    ISSN: 1432-0568
    Keywords: Cerebellum ; Neurogenesis ; Autoradiography ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Time of origin of various neuronal elements in the cerebellum of rat was established with the aid of tritiated-thymidine-autoradiography. The earliest nerve cells to form were the Purkinje cells, and they came into existence on days 15 and 16 of gestation. Interstitial nerve cells had their genesis on days 15, 16, 17 and 18, and the marginal cells on day 16 of the embryonic development. The Golgi cells were found to come into existence on days 17, 18 and 19 of gestation. On day 21 of gestation a number of small-medium-sized nerve cells, which were smaller than the Golgi cells but larger than the granule cells, were seen to come into existence. Finally, the earliest stock of granule, basket and stellate cells, primarily in the nodulus, flocculus and para-flocculus, were observed to have been formed on the day 21 of embryogenesis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 29 (1972), S. 39-49 
    ISSN: 1432-0738
    Keywords: Mouse ; Rat ; Brain ; Light-Dark-Programming ; Circadian ; Toxicity Rhythms ; Acetylcholine ; Pilocarpine ; Oxotremorine ; Carbachol ; Physostigmine ; Neostigmine ; Atropine ; Scopolamine ; Atropine Methyl Nitrate ; Maus ; Ratten ; Gehirn ; Beleuchtungsprogramm ; Circadianer Toxicitätsrhythmus ; Acetylcholin ; Piloearpin ; Oxotremorin ; Carbachol ; Physostigmin ; Neostigmin ; Atropin ; Scopolamin ; Atropin-methylnitrat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach Adaptation an ein Licht-Dunkelprogramm (8.00 bis 20.00 Licht, 20.00 bis 8.00 Dunkelheit) wurde der Acetylcholingehalt (ACh) im Mittelhirn und N. caudatus von Ratten sowie im Gesamthirn von Mäusen bestimmt. Die höchsten ACh-Konzentrationen wurden bei Ratten um 24.00 gefunden; die höchsten ACh-Werte bei der Maus waren nicht signifikant von den Konzentrationen um 24.00 und 12.00 verschieden. Signifikante ACh-Minima traten im Mittelhirn der Ratte um 12.00, im N. caudatus sowie im Mäusegehirn um 18.00 Uhr auf. Während der Dunkelperiode wurde die größte Toxicität gegenüber i.v. bzw. i.p. injiziertem ACh bei Mäusen gefunden. Ähnliche zeitliche Unterschiede ergaben sich für Neostigmin, Pilocarpin und Oxytremorin. Die Toxicität von Carbachol zeigte Maxima bei 12.00 und 24.00. Für Physostigmin, einen CholinesteraseHemmstoff mit einem tertiären Stickstoff, lagen sowohl die Toxicitätsmaxima als auch die Toxicitätsminima in der Dunkelperiode. Die rhythmische Schwankung der Toxicität von i.p. verabfolgtem Atropin verhielt sich umgekehrt wie die der Cholinomimetica (außer Carbachol). Auch nach i.v. Applikation von Scopolamin und N-Methylatropin war ein entsprechender rhythmischer Einfluß auf die Toxicität nachweisbar. Die Vorbehandlung mit N-Methylatropin schwächte die Toxicität zwar ab, der Toxicitätsrhythmus gegenüber ACh und Physostigmin war aber nicht verändert. Die Toxicität von Cholinomimetica zeigt ein Maximum während der höchsten ACh-Konzentrationen im Gehirn und der höchsten Stoffwechselaktivität. Bei den anticholinergen Substanzen zeigte sich ein umgekehrtes Verhältnis. Die Beziehungen zum zentralen ACh-Gehalt sind unklar.
    Notes: Abstract Acetylcholine (ACh) levels were determined in rat midbrain and caudate nucleus and mouse whole brain in mature animals adapted 3 weeks to a programmed lighting schedule (08:00 to 20:00 h light; 20:00 to 08:00 dark). Peak ACh levels in the rat occurred at 24:00 h; in the mouse the peak at 06:00 h did not differ significantly from values obtained at 24:00 and 12:00 h. Significant trough values occurred at 12:00 h in rat midbrain and at 18:00h in rat caudate nucleus and mouse brain. In mice toxicity of I.V. and I.P. administered ACh is maximal during the dark. Neostigmine, pilocarpine and oxotremorine have toxicity patterns similar to ACh. Carbachol toxicity peaked at 12:00 and 24:00 h. With physostigmine, a tertiary anticholinesterase, peak and trough occurred during the dark. The atropine (I.P.) toxicity rhythm is a mirror image of the cholinomimetic rhythm (except for carbachol). I.V. scopolamine and atropine methyl nitrate patterns resemble atropine's but are less clear-cut. Atropine methyl nitrate pretreatment reduced ACh and physostigmine toxicity but did not alter the overall pattern. Cholinomimetic toxicity and brain ACh patterns are similar, peaking when metabolic activity is maximal. An inverse relationship holds for the anticholinergic drugs. The relationship to central ACh is uncertain.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 15 (1972), S. 29-38 
    ISSN: 1432-1106
    Keywords: Ventromedial hypothalamus ; Single units ; Spontaneous and stimulated activity ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The relationship between mean firing rate and activity pattern was studied in 177 neurons in the ventromedial hypothalamus of rats immobilized by Remyolan. Stationary epochs of spontaneous or stimulated activity containing at least 512 interspike intervals were analyzed with the LINC computer. The most frequently encountered interval histograms (IHs) were of the exponential (35%) or gamma 2 (25%) type. The IH shape remained unchanged even if the average firing rate was varied over a wide range (from 20/sec to 2/sec) by polarization through the recording microelectrode (2–5 nA, 1–10 min) or by intracarotid injection of glucose (0.1 ml, 10–25%). The coefficient of variation (CV = SD/ mean interval) was 1.03 for the spontaneous and 0.90 or 0.95 for the activity influenced by polarization or glucose, respectively. Since according to other studies sensory stimulation decreases CV by reorganization of the synaptic input, it is suggested that polarization and glucose affect predominantly the postsynaptic elements without significantly changing the presynaptic activity pattern.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 20 (1972), S. 248-257 
    ISSN: 1432-0533
    Keywords: Experimental CNS Tumours ; N-Nitrosomethylurea ; Ethylnitrosourea ; Cell Culture ; Clonal Growth ; Aggregation Pattern ; Transplantation ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two sarcomas, one neurosarcoma and one polymorphous tumour of uncertain classification of the central nervous system of the rat induced by N-nitrosomethylurea or ethylnitrosourea were the source of 14 clones. The cytomorphology and the aggregation pattern of the clonesin vitro are described. The malignancy and histology were checked by homologous transplantation. All the clones formed sarcoma-like structuresin vivo, but it was difficult to decide whether these neoplasias were real sarcomas or very dedifferentiated glial tumours. The differences in cytology observedin vitro were greater than the histological differencesin vivo.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 18
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 22 (1972), S. 269-271 
    ISSN: 1432-0533
    Keywords: l-DOPA ; Neoplasm, Striatal ; Motor Behavior ; Rat ; Catecholamines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary After administration ofl-DOPA to a rat with a unilateral striatal neoplasm of the nucleus caudatus-putamen, postural asymmetries and rotating behavior were observed. These observations are discussed in relation to the activity of catecholamines within the central nervous system.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 19
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 24 (1972), S. 449-455 
    ISSN: 1432-2072
    Keywords: Avoidance and Acquisition ; Methamphetamine ; Discrimination Learning ; CNS Stimulants ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Avoidance responses, extra responses (on avoidance lever) and wrong lever responses were measured in naive rats acquiring a discriminated avoidance in a 2 lever Skinner box, 30 min after methamphetamine (0.25, 0.5 and 1.0 mg/kg). The smallest dose was ineffective; 0.5 and 1.0 mg/kg significantly increased the number of avoidance responses. This increase was not associated with a significant increase in the two other responses studied. The progressive increase (from the first to second part of the acquisition session) in avoidance responses was not accompanied by a parallel increase in the other responses. The position discrimination and the discrimination of the presence or absence of the conditioned stimulus was observed to be better in the drug groups.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 26 (1972), S. 195-200 
    ISSN: 1432-2072
    Keywords: Forced Motility ; Motor Activity ; Brain Noradrenaline and 5-Hydroxytryptamine ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The levels of 5-HT and 5-HIAA in the rat brain were measured after 1, 6, 24 and 36 h of forced motility in a treadwheel. The results showed that 5-HT metabolism had already increased in the forebrain after 1 h of exercise but later also increased in the brain stem, especially in the mesencephalon-pons-medulla regions. These changes had almost entirely disappeared after 50 min of rest. The NA levels with and without monoamine oxidase inhibitor were measured in animals after 36 h of forced motility. The results indicated an increase in NA metabolism in the brain stem.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 21
    ISSN: 1432-2072
    Keywords: Agressive Behaviour ; Apomorphine ; Testosterone ; Testes ; Hypophysis ; Adrenal Glands ; Thyroid ; Castration ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The weights of testes, prostates, adrenals, thymus and the pituitary of rats with apomorphine induced aggressiveness did not differ from those without aggressiveness. Postpubertal castration, adrenalectomy or thyroidectomy did not reduce the apomorphine induced aggressive behaviour, but a considerable reduction was found after hypophysectomy. Prepubertal castration significantly reduced, but did not completely abolish the proportion of aggressive rats, especially when castration was performed on the 5th day. Prolonged treatment of male, female and castrated rats with high doses of testosterone from the time of weaning increased the proportion of aggressive animals. Less intensive treatment and treatment of adult rats were ineffective.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 22
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 26 (1972), S. 317-320 
    ISSN: 1432-2072
    Keywords: Oxazepam ; Conflict Behavior ; Rat ; Maze
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Rats were tested in a Lashley III maze, the floor of which was heated. The animals had to learn to negotiate it in order to gain access to the unheated goal box. In the early period of training the animals were able to find the goal box rapidly and without error. Their performance then deteriorated, in a particular way which strongly evoked a conflict behavior. This deterioration in performance was progressively reduced by oxazepam administration (8 mg/kg/day).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 23
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 25 (1972), S. 218-228 
    ISSN: 1432-2072
    Keywords: Fighting ; Delta-9-Tetrahydrocannabinol ; Chlordiazepoxide ; Fixed-Interval ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The frequency with which electric shock to the feet elicited fighting in five pairs of albino rats was not altered significantly by intraperitoneal injections of delta-9-tetrahydrocannabinol (THC) in doses ranging from 0.064–6.4 mg/kg, although chlordiazepoxide reduced the frequency of such fighting in a dose-related manner. This finding held true despite manipulations of THC vehicle, injection-test interval, and the previous drug experience of the subjects. In contrast, doses of 4.0 mg/kg produced a striking reduction in lever-pressing maintained by an FI 60″ schedule of food reinforcement.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 24
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 23 (1972), S. 171-179 
    ISSN: 1432-2072
    Keywords: Reserpine ; Neonatal Treatment ; Sexual Behaviour ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate whether reserpine given in the critical period of sexual differentiation of the rat brain affects adult sexual behaviour, female and male rats were given a single injection of reserpine on the fourth day after birth, and their sexual behaviour was tested at maturity. In the 11 consecutive daily tests for spontaneous sexual behaviour the reserpine treated female animals showed fewer regular behavioural and vaginal oestrous cycles than the control animals. 19 % of the reserpinized and none of the control animals had prolonged oestrous behaviour without a coincident prolonged vaginal cycle. The reseptivity quotients of the reserpine treated animals were reduced. In the tests for hormone induced sexual behaviour after ovariectomy no statistically significant differences between the number of animals responding or between the receptivity quotients occurred. The tests for spontaneous sexual behaviour in males showed that the reserpinized animals needed fewer intromissions to ejaculate than the controls. The significance of these findings is discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 25
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 26 (1972), S. 347-360 
    ISSN: 1432-2072
    Keywords: Chronic Nicotine ; Attention Task ; Arousal ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Male, Holtzman rats were trained extensively on an attention task which required them to respond with a single lever-press to a very short, variably presented stimulus for food reinforcement, but which also required them to inhibit inappropriate responses. After performance had stabilized, two groups were treated with either nicotine base (100 Μg/kg, s.c., t.i.d.) or saline for 4 weeks. The groups were crossed-over so that the first received saline and the second nicotine for an additional 4 weeks. A 3-week saline recovery period followed. Rats were tested on the attention task daily through all periods. Analysis of the data indicated that independent of the treatment-order, rats performed more efficiently under nicotine treatment than under saline conditions. The improvement in performance was most notable in the reduction of inappropriate responding during chronic nicotine treatment. The significance of the behavioral changes in relation to proposed nicotine-induced neurophysiological changes and the two-arousal hypothesis are discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 26
    ISSN: 1432-2013
    Keywords: Cardiac Output ; Blood O2 Dissociation Curve ; High Altitude ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In rats adapted to a simulated altitude of 3500 m cardiac output measured at hypoxia by the direct Fick principle was significantly lower than in the control animals (mean values 54.3 ml/min and 69.8 ml/min, resp.). The decrease of cardiac output was accompanied by an increase of arterio-venous O2 difference and a decrease of stroke volume in the adapted rats. It is suggested that the decrease of cardiac output might be related to the increase of hematocrit. The adapted rats also showed higher arterial and mixed-venous O2 content (both at hypoxia) and increased O2 capacity. Arterial O2 saturation of the animals previously exposed to simulated high altitude hypoxia was significantly higher (67.3% as against 61.2% in the controls). The standard O2 dissociation curve showed lower oxygen affinity in the blood of the adapted animals but no physiological advantage concerning the transport of O2 to the tissues was found. In another group of animals the Bohr factor was estimated and no difference was found between rat and human blood.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 27
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 335 (1972), S. 198-212 
    ISSN: 1432-2013
    Keywords: Intestinal Absorption ; Medium Chain Fatty Acids ; Kinetics ; Active Transport ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. The transport of14C-octanoate by rat small intestine was determined in vitro by a modification of the method of Semenza and Mühlhaupt, and in vivo by using isolated segments or a perfusion technique in conscious rats (Haberichet al., 1968). 2. The absorption capacity of14C-octanoate in the distal ileum was significantly lower than in the proximal jejunum. 3. 14C-octanoate injected into a jejunal segment appeared rapidly in portal venous blood reaching its maximal concentration 4 min after the injection. 4. The transport of octanoate showed a saturation effect with increasing concentrations after an incubation of 4 min. However, with constant concentrations of octanoate in the medium, the transport rate was constant for 8–10 min. A similar saturation effect was also demonstrated in vivo. Values for maximal absorption rate (V max) and the half-saturation constant (K m), calculated from the Lineweaver-Burk plot, were 1.0 μMol/min and 17.7 mM, respectively. 5. Accumulation of octanoate in tissue water was demonstrated. For example, after incubation for 40 min in a medium concentration of 0.1 mM, the tissue/ medium ratio was 2.75:1. 6. Cyanide (2×10−4 M) markedly diminished the absorption rate of octanoate. 7. The absorption of octanoate was competitively inhibited by caproic acid (C6) in vitro. The inhibition constant (K i), calculated from the Dixon plot, was 47 mM. 8. Simultaneous administration of glucose and octanoate in vivo did not affect the absorption rate of the fatty acid. 9. These results suggest that the intestinal absorption of octanoate is an energy-dependant active process.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 28
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 334 (1972), S. 293-302 
    ISSN: 1432-2013
    Keywords: Lactate Turnover ; l-Lactate14C (U) ; Hypoxaemia ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Lactate turnover was measured in 24 anesthetized rats using14C-U-(l) Lactate with the priming dose-infusion technique. 2. 14C Lactate in blood was determined with a specific radio-enzymatic micromethod. 3. Lactate turnover increases with blood lactate concentration in the range 0.5 to 3 mM. In a steady state system this relationship means that a new equilibrium may be achieved at a higher pool level, between lactate production and utilization. 4. Comparing available data in four mammalian species lactate turnover at normal lactate levels was found to be approximately constant when computed on a body surface unit basis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 29
    ISSN: 1432-2013
    Keywords: Cardiac Hypertrophy ; Diffusion Distance ; High Altitude ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In growing rats adapted to a simulated altitude of 3500 m for about 4 weeks and in their controls the evolution of cardiac ventricular weight was followed. The increase of total ventricular weight found in the adapted animals can be attributed exclusively to the increase of right ventricular weight. In other adapted and control animals cardiac capillary densities, muscle fiber diameter and external capillary radius were estimated and fiber—capillary ratio and diffusion distance were calculated. There was an increase of capillary density together with a decrease of muscle fiber density, fiber-capillary ratio and diffusion distance in the right but not in the left ventricle of the adapted rats. The muscle fiber diameters, however, were larger in both heart ventricles of the rats exposed to a simulated high altitude, especially in the right ventricle. This indicates that true hypertrophy of the muscle fibers is mainly responsible for the increase of right ventricular weight. In the left ventricle, however, a hypertrophy of the muscle fibers together with a decrease of stroma components is demonstrated. The physiological importance of the shorter diffusion distance in the right ventricle of the high altitude adapted rats is discussed and it is suggested that the shorter diffusion distance may help to keep the tissue O2 partial pressure above the critical value, mainly also in extreme situations with high myocardial O2 consumption.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 30
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 331 (1972), S. 357-364 
    ISSN: 1432-2013
    Keywords: Thoracic Aorta ; Complex Dynamic Young's Modulus ; Age ; Serum Lipids ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 2 groups of male albino rats (wistar-strain), 6 months and 18 months of age, dynamic Young's moduli in longitudinal direction were measured, at 5 different frequencies between 1 and 5 Hz. Each group consisted of 10 animals. Measurements were made at the natural length and at 1.2 times this length. From each animal several serum lipids were determined. It was found that: 1. measured at the natural length and 1.2 times this length, no significant difference of dynamic Young's moduli between both age groups could be demonstrated 2. concerning the dynamic Young's moduli there is significant interaction between stretch level and age 3. retraction was significantly smaller in the old rats than in the young ones 4. the old animals had a significantly higher serum lipid content than the young rats 5. no correlation between serum lipids and Young's moduli could be demonstrated.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 31
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 337 (1972), S. 71-79 
    ISSN: 1432-2013
    Keywords: Rat ; Hypothalamus ; Prolactin ; LH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Plasma levels of prolactin and LH were measured by radioimmunoassay following electrochemical stimulation of the medial preoptic area (MPO) or the arcuate nucleus (Arc.N.) in pentobarbital anesthetized proestrous rats. Differences in the secretion pattern of prolactin and LH were observed when stimulated by means of acutely or chronically implanted electrodes. Acute implantation and stimulation of the MPO resulted in no change in serum prolactin levels, whereas stimulation by means of chronically implanted electrodes evoked a marked increase in serum prolactin. The general observation was that electrostimulation in the acute experiments causes a less sharp but more prolonged prolactin and LH release from pituitary than stimulation through chronically implanted electrodes.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 32
    ISSN: 1432-2013
    Keywords: Pulmonary Diffusing Capacity ; Alveolar-arterial O2 Pressure Difference ; High Altitude ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Steady-state pulmonary diffusing capacity for CO and alveolar-arterial O2 pressure differences were measured at hypoxia in growing rats adapted to a simulated altitude of 3500 m. The pulmonary diffusing capacity was significantly higher and the alveolar-arterial gradients were significantly lower in the adapted animals as compared with the controls exposed to hypoxia for the first time. The increased diffusing capacity could be explained entirely by the increase of blood O2 and CO capacity whereas the decrease of gradients might be explained by the increase of blood O2 capacity together with an increase of the arterio-venous O2 difference.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 33
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 202 (1972), S. 21-36 
    ISSN: 1432-1459
    Keywords: Hydrocephalus, Experimental ; Ethylnitrosourea ; Experimental Hydrocephalus ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 25 mg/kg Äthylnitrosoharnstoff wurden am 9 1/2. Tag der Schwangerschaft SD-JCL-Ratten injiziert. Die Feten wurden am Termin excidiert und mit dem Stereomikroskop untersucht. 78% der Feten zeigten einen Hydrocephalus. Die histologische Untersuchung in Stufenschnitten des Gehirns zeigte eine Stenose des Aquädukts ohne subependymale Gliose, ödematöse Plexus chorioidei mit prallgefüllten Gefäßen, spärlichem Bindegewebe und geschwollenen Epithelzellen, Verdünnung der telencephalen Wandungen mit schwach entwickelter granulärer Schicht und in der ependymalen Zone verbleibenden Neuroblasten. Die Entwicklung der jungen Ratten wurde studiert. 75% der neugeborenen Ratten zeigten klinisch gewisse Hinweise auf den Hydrocephalus. Stark betroffene Tiere wurden zunehmend somnolent und/oder gelähmt und starben meist vor Ende der 4. Woche. Der Eiweißgehalt des Liquors war nennenswert vermehrt. Es wurden subdurale, subarachnoidale und intraventrikuläre Blutungen beobachtet und als wahrscheinliche Todesursache angesehen. Die histologische Untersuchung der hydrocephalen Jungtiere ergab eine Abflachung der Ependymzellschicht und pralle Füllung corticaler Gefäße von der 2. Woche an. In späteren Stadien wurde eine Dickenabnahme der periventrikulären weißen Substanz, im besonderen im Bereiche des Occipitalhornes nachgewiesen. Im verdünnten Pallium waren Vacuolenbildungen des perineuralen Gewebes zu sehen, Verbreiterung der Virchow-Robinschen Räume und eine dem Status spongiosus ähnliche Degeneration. Verschiedene Formen ependymaler Wucherung wurden gesehen. Die vorliegende Studie stellt die erste postnatale Beobachtung von transplacentar verursachtem kongenitalem Hydrocephalus in der Ratte dar. Die hier beschriebene Technik erwies sich als einfaches und reproduzierbares Mittel, um einen kongenitalen Hydrocephalus in der Ratte zu erzeugen.
    Notes: Summary SD-JCL rats were injected with 25 mg/kg of ethylnitrosourea on day 9 1/2 of gestation. Fetuses were excised near term and examined under dissecting microscope. 78% of viable fetuses were found to be hydrocephalic. On the histologic study of the serial sections of the brain, a stenosis of the Sylvian aqueduct without subependymal gliosis, edematous choroid plexus with engorged vessels, scanty connective tissue and swollen epithelium, thinning of the telencephalic wall with poorly developed granular layers and the neuroblasts remaining in the ependymal zone, were the characteristic findings in the hydrocephalic fetuses. The natural course of the treated young rats was studied. 75% of the newborn rats showed some clinical evidence of hydrocephalus. Severely affected rats became progressively lethargic and/or paralytic, and died usually before the end of 4th week. Protein content of the cerebrospinal fluid was significantly increased. Subdural, subarachnoid and intraventricular hemorrhages were observed and suspected to be the cause of death. On the histological examination of hydrocephalic youngs, flattening of the ependymal cells and engorgement of the cortical vessels were observed as early as in 2-week-old youngs. In more advanced stages, there was noted the thinning of the periventricular white matter, especially around the occipital horn. The thin pallium showed vacuolization of the perineural tissue, enlargement of the Virchow-Robin space and the status spongiosus-like degeneration. Various types of ependymal proliferation was seen. The present study represents the first postnatal observation of the transplacentally induced congenital hydrocephalus in the rat. The present technique proved to be a simple and reproducible model of producing a congenital hydrocephalus in the rat.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 34
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 159 (1972), S. 114-123 
    ISSN: 1433-8580
    Keywords: Scalds ; Local cooling ; Rat ; Quantity of leucocytes ; Verbrühung ; Lokale Kühlung ; Ratte ; Verhalten der Leukocyten
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Untersuchungen an Ratten ergaben folgende Befunde: 1. Sofortige lokale Kühlung nach der Verbrühung beeinflußt bei der Ratte im untersuchten Zeitraum von 15 Tagen den Verlauf der Erkrankung gemessen am Parameter der Leukocytenzahl. 2. Die Kühlungszeit muß ausreichend lang sein. 3. Die Kühlung muß früh genug einsetzen, beim Versuchstier Ratte innerhalb 5 min nach Verbrühung. 4. Bei verspätetem Kühlungsbeginn läßt sich auch durch Verlängerung der Kühlungsdauer das Verhalten der Leukocytenzahl im Ablauf des Krankheitsgeschehens nach Verbrühung nicht beeinflussen.
    Notes: Summary Following results are obtained in experiments with rats: Immediate local cooling after scald had a significant influence on progress of “burn-disease”. Time for local cooling must be long enough, onset of local cooling early enough. It is not possible to restore the consequences of a late onset by prolongation of cooling.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 35
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 203-204 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 36
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 37
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 243-250 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Nonmetallic high-temperature materials. Some special ceramics are considered as materials for applications above 1100°C. They exhibit good heat strength, excellent corrosion resistance and with some limitations sufficient thermal shock and impact resistance. Compared to metals, this interesting type of materials require more development.
    Notes: Einige Sonderkeramiken kommen als Werkstoffe für Temperaturbeanspruchungen oberhalb von 1100°C in Betracht. Sie verfügen über ausreichende Warmfestigkeiten und gute Korrosionseigenschaften und mit einigen Einschränkungen auch über einen brauchbaren Thermoschock- und Schlagwiderstand. Im Vergleich zu den Metallen ist diese interessante Materialklasse noch sehr entwicklungsfähig.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 38
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 250-258 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Diffusion Bonding of Titanium Alloys. Diffusion bonding is a 4 stage process involving surface deformation atomic bonding interface diffusion and grain growth. These processes can proceed in the above order or more or less simultaneously. The effect of production parameters and material properties on the basic mechanisms is investigated. Several diffusion bonding techniques for industrial applications have been developed and are discussed in detail. Experience with the diffusion bonding of titanium alloys has shown that base material properties may be obtained in the weld zone. Actual parts fabricated by diffusion bonding sometimes show higher strength than made without welding. Some of the difficulties associated with diffusion bonding are presented. The economical and technical advantages of the diffusion bonding process are shown by reference to typical applications where this technique can be successfully applied.
    Notes: Beim Diffusionsschweißen laufen teils nacheinander, teils gleich-zeitig vier Prozesse ab: Oberflächenverformung, atomare Bindung, Grenzflächendiffusion und Kornwachstum.- Es wird untersucht, wie diese einzelnen Vorgänge jeweils von den technologischen Verfahrens-und Materialparametern abhängen, wobei teilweise eine mathematische Erfassung möglich ist. Für die technische Durchführung der Diffusionsschweißung stehen mehrere Verfahren zur Verfügung, deren Vorteile und Nachteile diskutiert werden. - Die bisherigen Erfahrungen mit dem Diffusions-schweißen von Titanlegierungen haben gezeigt, daß in der Schweißnaht Grundmaterialfestigkeit erreicht werden kann, bei manchen Bauteilen ergeben sich sogar Festigkeitsgewinne. Typische Fehlerquellen beim Diffusionsschweißen von Titan werden aufgezeigt. Abschließend wird anhand von Beispielen auf die Einsatzgebiete eingegangen, wo das Diffusionsschweißen wirtschaftliche und konstruktive Vorteile erbringen kann.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 39
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 40
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 41
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 394-414 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: New Developments in Powder Metallurgy. The new development in powder metallurgy is discussed with special emphasis of technological aspects. The most important meetings held during the last years as well as some other literature have been considered. After introductory paragraphes the basic technologies and then the materials itselves are discussed. The limits to the field of ceramics are fixed by involving metallic hard compounds (carbides), but leaving out nonmetallic materials. Also compound materials with metallic components are considered. In the following paragraph on basic investigations some approaches with importance for further technological development are focussed. The competition with other technological processes, opening of new groups of materials for powder metallurgy, new technological processes, new fields of application, successes and sometimes failures make considerable dynamics in this field.
    Notes: Es wird die neuere Entwicklung der Pulvermetallurgie unter vorwiegend technologischen Gesichtspunkten dargestellt. Hierzu wurden besonders die wichtigen Tagungen der letzten Jahre und eine Auswahl der Zeitschriftenliteratur berücksichtigt. Nach einem einführenden Abschnitt werden zunächst die wichtigsten technologischen Grundlagen (Ausgangsstoffe, Formgebung, Sintern, Drucksintern u. a.) und anschließend die Werkstoffgruppen besprochen. Die Abgrenzung zur Keramik erfolgt durch Einbeziehung der metallischen (Karbide), aber Nichtberücksichtigung der nichtmetallischen Hartstoffe. Auch Verbundwerkstoffe mit metallischen Komponenten finden Erwähnung. Im folgenden Abschnitt über grundsätzliche Untersuchungen wird auf Teilgebiete hingewiesen, deren Bearbeitung auch für die technologische Weiterentwicklung nützlich sein dürften. Durch die Wettbewerbssituation mit anderen Fertigungstechniken, die Erschließung neuer Werkstoffgruppen, Technologien und Anwendungsgebiete, durch Erfolge und gelegentliche Rückschläge, ist dieses Gebiet von besonderer Dynamik.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 42
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 425-432 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Der Stand der topologischen Betrachtungsweise von Sintervorgängen. Die topologischen Verfahren, die zur Beschreibung der Geometrie von gesinterten Gefügen herangezogen werden können, und die topologischen Ergebnisse, die bisher gewonnen wurden, werden kurz beschrieben. Obwohl die Ergebnisse noch ziemlich begrenzt sind, so liefert ihre Kombination mit metrischen Meßdaten doch die Grundlage für eine quantitative Beschreibung der Entwicklung der Gefügegeometrie während des Sinterns. Zwei einander widersprechende Gesichtspunkte für diese geometrische Entwicklung werden diskutiert.
    Notes: The topological concepts which have been applied to describe the geometry of sinter structures and the topological data which has been obtained to date are briefly presented. This data, although limited in extent, when combined with the metric data provides the basis for a quantitative description of the geometric evolution accompanying the sintering process. Two contrasting viewpoints of this geometric evolution are briefly presented.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 43
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 439-441 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 44
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 441-447 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 45
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 18-21 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Contribution to Studies of fracture in thin bituminous films. A recently published theory of crack propagation in viscoelastic materials is briefly reviewed. This theory serves as a basis for a newly developed hypothesis describing the fracture process in thin bituminous films. Observation of fracture surfaces with the help of a scanning electron microscope showed that microcracks start from the weakest points (inhomogeneities) in the matrix. By increasing the external load disk-shaped cracks increase as a function of the applied load. Only when the critical mean crack diameter is reached macroscopie failure occurs. Fractographic methods proved to give detailed information about fracture process in thin bituminous films.
    Notes: Eine an anderer Stelle ausführlich beschriebene Theorie der Rißausbreitung in viskoelastischen Stoffen wird kurz dargestellt. Daraus läßt sich eine Hypothese zum Bruchvorgang in dünnen Bitumenfilmen ableiten. Mit Hilfe von Raster-Elektronenmikroskop-Aufnahmen an Bruchflächen von Bitumenfilmen konnte die Vorstellung, daß bei einer Belastung zunächst in Inhomogenitäten des Materials Mikrorisse entstehen, bestätigt werden. Von diesen „Griffith-Rissen“ breiten sich bei Laststeigerung scheibenförmige Risse in einer Ebene senkrecht zur aufgebrachten Spannung aus. Sobald ein mittlerer kritischer Radius dieser sekundären Risse erreicht wird, tritt der makroskopische Bruch ein. Es hat sich gezeigt; daß fraktographische Methoden in der Lage sind, wertvolle Beiträge zum Studium des Bruchvorganges dünner Bitumenfilme zu liefern.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 46
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 47
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 55-55 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 48
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 110-111 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 49
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 50
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 111-111 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 51
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 111-111 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 52
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 112-112 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 53
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 54
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 55
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 56
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 130-133 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Crack Arrest Behaviour of Structural Steels. Medium scale tests are described by which it is possible to estimate the crack arrest behaviour, usually characterized by the Robertson-Test or Double Tension Test. Tests on 16 steels show that the critical temperature for an instable fracture during the sharp-notch slow bend test corresponds largely with the crack arrest temperature determined in the Robertson-Test. A regression equation is given for the relation of the results of both tests. - A distinct relation between the crack arrest temperature of the Robertson-Test on the one side and the transition temperatures measured in the notched bar impact test, the Coheracy test and the drop-weight test on the other side was not observed.
    Notes: Es werden Versuche beschrieben, nach denen man das Rißauffangvermögen, das üblicherweise durch Robertson-Test oder Double Tension-Test gekennzeichnet wird, unter Verwendung von Proben mittlerer Abmessung abschätzen kann. Nach Untersuchungen an insgesamt 16 Stählen stimmt die kritische Temperatur für das Auftreten eines instabilen Bruches im Scharfkerbbiegeversuch mit der im Robertson-Test ermittelten Crack Arrest-Temperatur gut überein. Für die Beziehung beider Größen wird eine Regressionsgleichung angegeben. Ein strenger Zusammenhang zwischen Crack Arrest-Temperatur des Robertson-Testes einerseits und den in Kerbschlagbiegeversuch, Kohärazieprüfung und Drop Weigth-Test gemessenen Übergangstemperaturen andererseits konnte nicht beobachtet werden.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 57
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 58
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 211-222 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 59
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 222-222 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 60
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 222-223 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 61
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 235-238 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Glass-Balls for Technical Application. Description of methods of producing glass-balls with a diameter of 1 to about 1000 μm and their application for shot blasting, reflecting and for filling material
    Notes: Herstellungsmethoden von Glaskugeln mit einem Durchmesser von 1 bis ca 1000 μm und die Verwendung dieser Kugeln als Strahlmittel, Reflexperlen und als Füllstoff werden beschrieben.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 62
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 239-243 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Adhesion and Interfacial Reactions in the αAl2O3/Ni Composite System. Composite models consisting of a zylindrical sapphire rod surrounded by a sintered nickel ring are used to determine the influence of small amounts of titanium or zirconium (as alloying additions in the nickel) on the adhesion and compatibility between the composite components. Poor nickel gives temporally and thermally stable-shear strength values between 50 and 70 N/mm2. With nickel containing 0,05 at.-% Ti or Zr the shear strength increases to 250-280 N/mm2 by using favourable sintering conditions (i. e. 1300°C, 1 h). This increase is caused by an improvement of adhesion which can be explained by the formation of strong chemical bonds. These bonds are produced by chemical reactions between the sapphire surface and the alloyed active metals Ti or Zr in the nickel. With longer sintering times, higher sintering temperatures, and/or higher active metal concentrations, these reactions cause roughening of the sapphire surface and precipitation of active metal oxide phases at the interface or in the adjacent nickel zone. Those reactions-caused alterations of the interface region are changing the shear behaviour and can lead to a decrease of shear strength. The shear strength values of such specimens dont allow conclusions of the real adhesion between the components.
    Notes: An Verbundwerkstoffmodellen aus zylindrischen Saphirstäben mit aufgesintertem Nickelring wird der Einfluß geringer Mengen von Titan oder Zirkon als Legierungsbestandteil im Nickel auf die Haftung und Verträglichkeit zwischen den Partnern unter-sucht. Mit unlegiertem Nickel werden zeitlich und thermisch stabile Scherfestigkeitswerte zwischen 50 und 70 N/mm2 erzielt. Enthält das Nickel 0,05 At-% Titan oder Zirkon, steigt bei günstigen Sinterbedingungen (z. B. 1300°C, 1 h) die Scherfestigkeit auf 250-280 N/mm2 an. Dieser Anstieg ist auf eine, Verbesserung der Haftung zwischen den Partnern zurückzuführen, die sich mit der Ausbildung chemischer Haftkräfte als Folge von Reaktionen zwischen der Saphiroberfläche und den im Nickel enthaltenen aktiven Legierungselementen Titan oder Zirkon erklären lassen. Bei längeren Haltezeiten, höheren Sintertemperaturen und/oder höheren Aktivmetallkonzentrationen führen diese Reaktionen zur Aufrauhung des Saphir und zur Ausscheidung von Oxidphasen der im Nickel enthaltenen aktiven Elemente in der Grenzfläche oder in einer grenzflächennahen Zone des Nickels. Diese reaktionsbedingten Grenzflächenveränderungen bewirken eine Änderung des Scherverhaltens, die sich in einer Verringerung der Scherfestigkeit äußern kann. Die an solchen Proben gemessenen Scherfestigkeitswerte lassen keine Rückschlüsse auf die tatsächliche Haftung zwischen den Partnern mehr zu.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 63
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 64
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 65
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 279-279 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 66
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 280-280 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 67
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 316-318 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 68
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 322-322 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 69
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 70
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 71
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 336-336 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 72
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 345-352 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Springs in precision mechanics and their materials. Springs of different types are important components for mechanical and electronic instruments. The properties required of the material follow as a result of the different problems for which the springs are designed. After a short classification of the field of task and uses the properties, their importance for function of the spring and the possibilities of testing are described. A Summary of materials for springs today in use is presented.
    Notes: Federn der verschiedensten Art bilden wichtige Bestandteile feinmechanischer und elektrotechnischer Geräte. Aus den unterschiedlichen Aufgaben, die diese Federn zu erfüllen haben, ergeben sich die Eigenschaften, die vom Federwerkstoff gefordert werden müssen. Nach einer Kurzen Klassifizierung der Aufgaben- und Anwendungsgebiete von Federn werden als Übersicht, Werkstoff-Eigenschaften, ihre Bedeutung für die Funktion der Feder, die Möglichkeiten der Prüfung und die heute gebräuchlichen Federwerkstoffe besprochen.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 73
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 280-280 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 74
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 282-286 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Recent Development in the Field of Welding Technique. Because of important advantages as soundness of gap, no overlapping and possibility of mechanization the welding procedure takes a considerable plave in the wide field of joint techniques. Often the mechanical properties of the weld metal exceed the values of the base metal.The following report describes recent welding techniques: welding with cored-wire electrodes, the narrow-gap-welding and electron-beam welding at atmosphere. This procedures are often used for the welding of new grades of materials.
    Notes: Im vorliegenden Beitrag sind anhand von ausgewählten Beispielen neue Entwicklungen auf einigen Gebieten der Schweißtechnik beschrieben. Diese Entwicklung wird durch wirtschaftliche Gesichtspunkte wesentlich beschleunigt und ist noch nicht an ihrem Ende angelangt.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 75
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 281-281 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 76
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 383-385 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 77
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 368-376 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Changes of the state of aggregation of metals due to the passage of strong shock waves. The heating of metals due to the passage of a shock wave is, in general, small because of the low compressibility of solids. Under the action of extremely strong shock waves, for instance in the applications of high explosives, the increase of temperature may however, be so high that after pressure release the metal is in the liquid state. This prediction is based mainly on theoretical calculations as the direct determination of temperature, and hence of the state of aggregation, is difficult because of the rapid rate of the processes involved.The investigation discussed here was aimed at demonstrating the possible melting of metals under shock loading by looking for specific phenomena characteristic of the state of aggregation. To do this, shock waves of different intensities produced by means of high explosives were passed through samples of partly metallic, partly nonmetallic, material. The state of aggregation after pressure release was determined by X-ray flash photography and by investigations of recovered parts of the samples. The investigations show in accordance with the theoretical predictions that only low-melting metals, such as lead or tin, are in the liquid state after pressure release, and even these only when high explosives with shock pressures of several hundred kilobars are applied. Apart from these cases shock loaded metals are in the solid state after pressure release, with a maximum increase in temperature of a few hundred degrees.
    Notes: Die Aufheizung von Metallen beim Durchgang von Stoßwellen ist wegen der kleinen Kompressibilität fester Körper im allgemeinen gering. Im Fall extrem starker Stoßwellen, beispielsweise bei der Anwendung von Sprengstoffen, kann der Temperaturanstieg jedoch so groß sein, daß das Metall nach der Druckentlastung flüssig ist. Diese Aussage stützt sich allerdings fast ausschließlich auf theoretische Berechnungen, da die direkte Bestimmung der Temperatur und damit des Aggregatzustands wegen der Kurzzeitigkeit der Vorgänge schwierig ist.Die vorliegende Arbeit hatte das Ziel, unter Verzicht auf direkte Temperaturmessung das mögliche Schmelzen von Metallen unter Stoßbelastung durch Untersuchung bestimmter, für den jeweiligen Aggregatzustand charakteristischer Erscheinungen nachzuweisen. Hierzu wurden durch Proben aus teils metallischen, teils nichtmetallischen Materialien mit Hilfe von Sprengstoffen Stoßwellen unterschiedlicher Stärke geschickt. Der Aggregatzustand nach der Druckentlastung wurde durch Röntgenblitzaufnahmen und Untersuchungen am aufgefangenen Material ermittelt. Es zeigte sich in Übereinstimmung mit der theoretischen Vorhersage, daß nur niedrigschmelzende Metalle wie Blei oder Zinn nach der Druckentlastung im flüssigen Zustand vorliegen und auch diese nur bei Anwendung hochenergetischer Sprengstoffe mit Stoßwellendrücken von einigen hundert Kilobar. Von diesen Fällen abgesehen sind stoßbelastete Metalle nach dem Stoßwellendurchgang im festen Zustand, mit einer Temperaturerhöhung von höchstens wenigen hundert Grad.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 78
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 392-392 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 79
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 415-419 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Hardenable Sintered Nickel-Molybdenum Alloy Steel. From all the posible alloying elements to be used for high-strength Powder-Metal-Steels, Nickel and Molybdenum should be preferred, particularly when heat treatment is required. As an example a P/M-Steel with 2,0% Ni and 0,5% Mo is being presented. The pros and cons of blends and prealloyed powders are being displayed as well as the physical properties as-sintered and as-heat treated.In general, high-strength sintered steels loose their ability to be calibrated because of their high yield strength and poor deformability. It is therefore very difficult to calibrate them to close tolerances, hence they cannot very often compete with other metal working procedures which would permit to achieve the required tolerance.The author describes the careful selection of the carbon concentration. Despite a tensile strength figure in the order of 80-90 kp/mm2 the material retained its ability to be manufactured to very close tolerances. The method by which the samples were prepared are described.The materials obtained from blends and prealloyed powders exhibit different structures; their influences on the physical properties are being explained.
    Notes: Aus sinterspezifischen Gründen ist den Legierungselementen Nickel und Molybdän bei der Herstellung eines hochfesten Vergütungssinterstahls mit ausreichender Durchhärtbarkeit der Vorzug zu geben. Am Beispiel eines Stahls mit 2% Nickel und 0,5% Molybdän werden das Prinzip des Mischlegierens und der Fertiglegierung vergleichend untersucht und die technologischen Eigenschaften im gesinterten und vergüteten Zustand mitgeteilt.Hochfeste Sinterstähle verlieren im allgemeinen wegen ihrer hohen Streckgrenze und der geringen Zähigkeit ihre Kalibrierbarkeit, so daß die gegenüber anderen konkurrierenden Fertigungsverfahren engen Maßtoleranzen nicht mehr einhaltbar sind. Durch eine genaue Auswahl des Kohlenstoffgehaltes ist es jedoch möglich, den vorliegenden Sinterstahl trotz des Festigkeitsniveaus von 80 bis 90 kp/mm2 mit hoher Maßgenauigkeit zu fertigen, wofür eine entsprechende Anleitung gegeben wird.Die unterschiedliche Gefügestruktur der Stähle aus dem Mischpulver und dem fertiglegierten Pulver werden aufgezeigt und ihr Einfluß auf die technologischen Eigenschaften beschrieben.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 80
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 420-424 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Hot Forged Materials from Steel Powders. Two types of materials are available: one type is derived from compositions of sintered steels with Cu, Ni, Mo as alloying elements where no comparisons with wrought steels are possible. The other one comprehend alloys with assimilated compositions of wrought heat treatable steels. Preference had been given first to alloying elements, which do not oxidize under neutral or slightly reducing atmosphere, e. g. steels of AISI 4600 serie.  -  In the mean time also cheaper raw materials e. g. low Cr.—Ni—Mn—Mo alloyed powders are used. The carbon content is adjusted by additions of graphite powder.  -  Differences in compositions in comparison to wrought steels exist in the silicon content, which is less than 0,10 % in opposite to 0,10 to 0,35 % in structural and heat treatable steels.  -  Yield-, tensile- and fatigue strength of powder forged materials are quite comparable with those of wrought steel of similar composition, while ductility, is a little bit less. Attention must be drawn, however, to the fact that the obtained values for elongation and impact strength are isotropical in the finished part, whereas the corresponding values of wrought steel will decrease rectangular to the forging direction, resp. to the direction of materials flow.
    Notes: Auf dem Werkstoffgebiet der Sinterschmiedestähle zeichnen sich zwei Entwicklungslinien ab; die eine baut auf den herkömmlichen Legierungen der Sinterstähle auf unter bevorzugter Verwendung der Legierungselemente Cu, Ni, Mo und C. Hier sind keine vergleichbaren Zusammensetzungen in der Schmelzmetallurgie vorhanden. Die andere lehnt sich an Zusammensetzungen der Bau- und Vergütungsstähle der Schmelzmetallurgie an. Hier wurden zunächst ebenfalls Legierungselemente bevorzugt, deren Oxidation unter neutraler oder leicht reduzierender Atmosphäre vermieden werden kann, wie z. B. Zusammensetzungen des Stahltyps AISI 4600. -  Mittlerweile ist man jedoch auch zu billigeren Rohstoffen, d. h. niedrig Cr—Mn—Ni—Mo—legierten Pulvern, denen Kohlenstoff in Form von Grafit zugegeben wird, übergegangen.  -  Unterschiede in der chemischen Zusammensetzung gegenüber schmelz metallurgisch hergestellten Stählen bestehen nur im Siliziumgehalt (max. 0,10% gegenüber 0,10-0,35 % bei den Bau- und Vergütungsstählen).Streckgrenzen-, Zug-und Dauerfestigkeitswerte der sintergeschmiedeten Werkstoffe stimmen gut mit den schmelzmetallurgisch hergestellten gleicher Zusammensetzung überein. Lediglich die Zähigkeitseigenschaften sind niedriger. Hierbei muß jedoch beachtet werden, daß diese etwas geringeren Zähigkeitseigenschaften am sintergeschmiedeten Bauteil in jeder Richtung erhalten werden, während die besseren Zähigkeitseigenschaften des erschmolzenen und dann umgeformten Bauteiles nur parallel zur Verformungsrichtung vorliegen. Das isotrope Eigenschaftsverhalten der sintergeschmiedeten Werkstoffe könnte für manche Bauteile von großem Interesse sein.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 81
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 436-437 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Radiographic equivalence factors for several common plastic materials were determined experimentally. The factors were calculated in relation to steel in an energy range from 50 to 150 keV.
    Notes: Für eine Reihe technisch wichtiger Kunststoffe wurden die Umrechnungsfaktoren auf gleichwertige Stahlwanddicke im Strahlenenergiebereich 50-150 keV experimentell ermittelt.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 82
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 83
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 13-17 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Diffusion in the contact zone of explosion-welded titanium-clad steel plates. After diffusion heat treatment, the intermetallic compounds Fe2Ti and FeTi were found to exist in the contact zone of titanium  -  Clad steel plates. The bond strength of these clad plates may possibly be impaired by the segregation of titanium carbide in the FeTi layer. In addition, cavities form adjacent to the intermetallic phases in the titanium after prolonged heat treatment. Titanium concentration in the fusion zones was found to be 55 ± 2 w/o (balance iron). After heat treatment of this specimen, FeTi was found to be predominant.
    Notes: Nach Diffusionsglühungen konnten in der Kontaktzone von Fe/Ti-Plattierungen die intermetallischen Verbindungen Fe2Ti und FeTi nachgewiesen werden. Die Haftfestigkeit dieser Plattierungen kann möglicherweise durch Ausscheidung von Titan-Karbid in der FeTi-Zone beeinträchtigt werden. Bei längerer Glühzeit bilden sich zusätzlich Löcher neben den intermetallischen Phasen im Titan aus. Die Titan-Konzentration in den Aufschmelzzonen konnte mit 55 ± 2 Gew.-% Titan (Rest Eisen) bestimmt werden. Nach einer Wärmebehandlung dieser Probe wurde überwiegend FeTi nachgewiesen.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 84
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 55-55 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 85
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 56-56 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 86
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 56-56 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 87
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 88
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 57-57 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 89
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 58-64 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Wear and wear Testing. The following six different wear mechanisms are briefly discussed: adhesive wear, abrasive wear, fatique wear, mechano-chemical wear and thermal wear. As to wear testing it is concluded that for obtaining a priori information on materials, laboratory testing can be quite useful, provided that the environmental conditions that prevail in practice are successfully reproduced in the laboratory. Further, it is always advisable to include in a test programme some reference materials on which practical information is available.
    Notes: Es wird eine Übersicht über die Grundprozesse, die beim Auftreten praktischer Verschleißfälle eine Rolle spielen können, gegeben. Unterschieden wird in: adhäsiven Verschleiß, Furchungsverschleiß und abrasive Erosion, Verschleiß durch Oberflächenermüdung, mechanochemischer Verschleiß und Schmelzverschleiß. Der Verlauf dieser verschiedenen Prozesse und der Einfluß verschiedener Prozeßparameter werden erörtert. Hinsichtlich der Verschleißprüfung wird darauf hingewiesen, daß man bei der Übertragung von Unterlagen aus dem Labor auf die Praxis mit Überlegung vorgehen muß. Im allgemeinen kann man nur eine sinnvolle Information über die relative Qualität von Materialien erwarten. Eine Grundbedingung hierzu ist aber noch, daß die Prüftemperatur und die Zusammensetzung der Umgebung in Übereinstimmung mit denen der Praxis gewählt werden. Außerdem empfiehlt es sich, eine Anzahl Referenzmaterialien, von denen Praxisunterlagen bekannt sind, in die Untersuchung mit einzubeziehen.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 90
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 91
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 167-167 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 92
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 168-168 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 93
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 168-168 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 94
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972) 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 95
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 197-203 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Refractory metals and alloys. The application of refractory metals such as niobium, tantalum, molybdenum, tungsten, chromium and rhenium at high temperatures is discussed on the basis of a compilation of their physical, chemical and technological properties. The present state of knowledge in this field indicates, that the high temperature strength needed can be obtained with some of the refractory alloys also at temperatures much higher than 1000°C. However, at present, the oxydation resistance has not yet been improved far enough to allow the use of these materials in air.
    Notes: Ausgehend von einer Übersicht über die physikalischen, chemischen und technologischen Eigenschaften der hochschmelzenden Metalle Niob, Tantal, Molybdän, Wolfram, Chrom und Rhenium sowie deren Legierungen werden die Anwendungsmöglichkeiten dieser Stoffgruppe als Hochtemperaturwerkstoffe besprochen.Der derzeitige Stand der Forschungs- und Entwicklungsarbeiten auf diesem Gebiet läßt erkennen, daß die von der Technik geforderten Warmfestigkeitswerte von einigen Legierungen auch bei Temperaturen oberhalb von 1000°C erreicht werden. Die Oxydationsbeständigkeit konnte dagegen bisher noch nicht so weit verbessert werden, daß eine Anwendung in Luft möglich erscheint.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 96
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 223-223 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 97
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 223-224 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 98
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 99
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 223-223 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 100
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 3 (1972), S. 223-223 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...