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  • 1
    ISSN: 1432-1017
    Keywords: Fluorescence polarization degree ; Fusion ; Label migration ; Lipid migration ; Cell membrane ; Virus envelope
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The fluorescence depolarization of 1,6-diphenyl-hexatriene was used to study the dynamic properties of the hydrophobic regions of the lipid envelopes of ortho- and paramyxoviruses as well as of the Rous sarcoma virus and of the membrane lipids of susceptible and nonsusceptible cells. The systems investigated where active and inactive influenza viruses, and NDV virus acting on chick embryo fibroblasts and Rous sarcoma virus acting on susceptible (C/E) and nonsusceptible (C/B) chicken-cell. Polarization degrees and mean rotational correlation times of DPH embedded in viral lipids were significantly higher than those of DPH in the cell membranes, due to a higher rigidity of the virus envelopes. When suspensions of labelled viruses and unlabelled cells or unlabelled viruses and labelled cells were mixed, a characteristic change of the fluorescence polarization degrees with time was observed. This behaviour was ascribed to a label transfer from virus to cell membranes or vice versa. While the rate constants of label transfer from virus to cells and cells to virus were about the same for the penetrating viruses the rate constants of label release from inactive virus to cells were much larger than for the migration in the opposite direction.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 21 (1942), S. 255-256 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es werden die an der Basler Universitäts-Frauenklinik ausgeführten Versuche mit Heparin (Liquemin „Roche“) eingehend beschrieben. Die erhaltenen Resultate gestatten keinen Schluß auf eine sichere prophylaktische oder therapeutische Wirksamkeit des Heparins. Weitere Versuche mit Heparin sind vorgesehen.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 22 (1943), S. 344-345 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es werden die in dieser Wschr.1942, 11 angekündigten weiteren Versuche mit Liquemin „Roche“ mitgeteilt, die an der Basler Universitäts-Frauenklinik und der Chirurgischen Universitätsklinik durchgeführt wurden. Im Gegensatz zu den früheren Versuchen wurden größere Dosen Heparin verabreicht und die Behandlungsdauer verlängert. Angabe von 2 Schemata für die prophylaktische Behandlung. Die erhaltenen Resultate sind auch jetzt nicht eindeutig, die prophylaktische und therapeutische Wirksamkeit des Heparins bleibt unsicher.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Sozial- und Präventivmedizin 7 (1962), S. 537-546 
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Après 20 ans d'expérience nous avons constaté que la vasoligature est la meilleure méthode de la stérilisation pour un couple. Les risques sont très limités, et l'opéré ne doit cesser son travail que durant peu de temps. Nous avons eu l'occasion de revoir à deux reprises 212 hommes, de 4 à 10 ans après leur opération. L'âge du couple et le nombre d'enfants ne jouent pas un grand rôle, pourvu que l'entente conjugale soit bonne. Ce qui est contre-indiqué, c'est qu'on force l'époux à accepter une vasoligature à cause d'une interruption. L'inconvénient de la méthode est que la fertilité subsiste jusqu'à ce que les vésicules séminales soient entièrement vidées, ce qui n'est en général le cas que deux mois après l'opération. Il y a aussi des gravidités extramatrimoniales, mais rarement et surtout chez des débiles. Quelques-uns de nos hommes doivent prendre soin d'enfants du premier lit ou des enfants illégitimes.
    Notes: Zusammenfassung Auf Grund einer zwanzigjährigen Erfahrung sind wir der Ansicht, daß bei einer operativen Sterilisation der Ehe, der Vasoligatur der Vorzug gegeben werden sollte. Das Risiko postoperativer Komplikationen ist gering, ebenso der Ausfall an Arbeitszeit. Wir konnten unter zwei Malen insgesamt 212 Männer nachuntersuchen, die vier bis zehn Jahre vorher operiert worden waren. Nur drei davon berenen heute den Eingriff. Alter und Kinderzahl spielen keine große Rolle, dagegen sollte die Ehe gut sein. Ungünstig wirkt sich aus, wenn die Zustimmung zu einer Interruptio von einer vorausgehenden Vasoligatur des Ehemannes abhängig gemacht wird, so daß er in eine Zwangslage versetzt wird. Nachteil der Methode ist das Andauern der Fertilität bis zur Entleerung der Samenblasen, was durchschnittlich zwei Monate dauert. Es sind auch extramatrimonale Schwangerschaften, namentlich bei Debilen, vorgekommen. Einzelne unserer Männer haben aber auch für Kinder aus erster Ehe und uneheliche Kinder zu sorgen.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Sozial- und Präventivmedizin 12 (1967), S. 313-314 
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Sozial- und Präventivmedizin 13 (1968), S. 187-190 
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 111 (1999), S. 3349-3356 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We revisit the far from equilibrium escape problem across a fluctuating potential barrier that is driven by asymmetric, unbiased dichotomous noise. Our closed analytical solution for arbitrary noise strengths reveals new aspects of the so-called "resonant-activation" effect and leads to interesting implications regarding far from equilibrium or externally controlled chemical reaction processes. Specifically, a genuine asymmetry-induced variant of resonant activation within the constant intensity scaling scheme is discovered, and a new possibility to manipulate reaction rates and yields, as well as the balance between reactants and products, is put forward. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 7186-7192 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Internal strains in cluster-compacted nanocrystalline Pd (crystallite size 10–20 nm) were studied by means of wide-angle x-ray scattering. The strain- and size-induced broadening of the Bragg diffraction peaks was determined by Hall or Warren–Averbach analyses. The Warren–Averbach analysis indicates a spatial confinement of internal strain fields. This result supports theoretical models according to which the sources of the stresses are located in the interfaces between the crystallites. Indirect further evidence for a stress localization is derived from recent findings on the variation of internal strains and atomic displacements with the crystallite size. In addition, an anisotropy of the line broadening was observed which cannot entirely be attributed to planar defects (maximum concentration 0.04) but indicates enhanced microstrains in the crystallographic 〈100〉 directions compared to the 〈111〉 directions. Based on this strain anisotropy, various distributions of microstresses are discussed taking into account the substantial elastic anisotropy of Pd. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 4897-4899 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: With two-photon excitation into the longitudinal exciton or into the excitonic continuum copper halides show laser emission at wavelengths of 413.3 nm (CuI), 422.5 nm (CuBr), and 391.9 nm (CuCl). The linewidth of the emission is very narrow in CuI and CuBr (below 0.004 nm) and much broader in CuCl (0.4 nm). The laser transition occurs between the bottleneck of the exciton polariton and the longitudinal optical phonon.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 112 (2000), S. 1844-1858 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Laser spectroscopy, i.e., resonant two-photon ionization (R2PI), IR/R2PI ion depletion and hole burning spectroscopy have been applied in an experimental study of heterogenous clusters consisting of fluorobenzene (FB) or p-difluorobenzene (pDFB), respectively, microsolvated by up to three methanol molecules. Their infrared ion depletion spectra were taken in the region of the OH and CH stretches of methanol. In these complexes the methanol molecules form subclusters, which are weakly hydrogen bonded to either the aromatic π-system (πOH) or to the fluorine substituent (σF) and a CH group (σCH). In FB⋅(MeOH)1, pDFB⋅(MeOH)1, pDFB⋅(MeOH)2 and one isomer of FB⋅(MeOH)2 the methanol subunits exclusively exhibit σF and σCH H-bonds. A further isomer of FB⋅(MeOH)2 exhibits a πOH type interaction. For FB⋅(MeOH)3 and pDFB⋅(MeOH)3 (1:3) complexes the methanol subcluster may take on either a chainlike or a ringlike conformation. In the chainlike isomer of FB⋅(MeOH)3 the methanol trimer interacts with the chromophore via a πOH H-bond while with the corresponding pDFB cluster a σF H-bond is formed. High level ab initio calculations, still feasible for molecular clusters of this size, have also been carried out to supplement the experimental investigations. These calculations include complete geometry optimizations of FB⋅(MeOH)n (n=1–2) and pDFB⋅(MeOH)1 at the MP2/6-31+G* and B3LYP/6-31+G* levels of theory. The minimum energy structures of the microsolvates together with their harmonic vibrational spectra allow a reliable assignment of the experimentally observed spectra and the determination of structure of the complexes. © 2000 American Institute of Physics.
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