ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The dried roots of Vincetoxicum hirundinaria MEDIKUS, collected in the lake of Garda area, yielded ca. 6% of a crude glycoside mixture, of which 5,16% consisted of relatively weakly polar material. After mild acid hydrolysis of the latter, 7 sugars could be identified through paper and thin layer chromatography, and paper electrophoresis. Of these D-cymarose, L-diginose, D-digitoxose, and a small amount of lilacinobiose could be isolated in crystalline form. Of the other three sugars, D-oleandrose was characterised as a crystalline derivative, whereas boivinose and canarose could only be identified through paper and thin layer chromatography, and paper electrophoresis.Four crystalline genins (B, D, E, G) and a glycoside (F) were isolated from the genin extract. Of these, D was very unstable and therefore thus was not further investigated. B, E, and F were shown to be 15-oxasteroids, a type of steroids so far not found in nature. Very probably, G also represents a 15-oxasteroid. The four substances B, E, G, and F were given the following trivial names: B = anhydrohirundigenin, E = hirundigenin, G = vincetogenin, and F = hirundoside-A. F is an oleandroside of anhydrohirundigenin. The structures of hirundigenin and anhydrohirundigenin have already been elucidated [35].
Additional Material:
20 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19690520504
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