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  • 1980-1984
  • 1970-1974  (1,683)
  • 1973  (929)
  • 1971  (754)
  • Organic Chemistry  (1,409)
  • Engineering General  (251)
  • pharmacokinetics
Material
Years
  • 1980-1984
  • 1970-1974  (1,683)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Diabetologia 9 (1973), S. 331-338 
    ISSN: 1432-0428
    Keywords: Diabetes mellitus ; sulphonylurea ; glipizide ; pharmacokinetics ; metabolism ; excretion ; renal insufficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Four subjects received 5 mg14C-glipizide orally and3 subjects1 mg intravenously. The average absorption of the oral dose was nearly 100% with peak plasma levels occurring between 90 and 360 min. The apparent half-life of plasma radioactivity was approximatively 3.7 h, the disappearance of radioactivity following complex kinetics due to metabolism of the drug. Extraction with CH2Cl2 and chromatography showed that in plasma 85% of the total radioactivity corresponded to unchanged glipizide, but in urine 98% to more polar and more readily excreted metabolites. The urinary excretion is 68% of the dose. The hypoglycaemic effect of glipizide is comparable to glibenclamide. The administration of14C-glipizide to two patients with renal insufficiency showed that the metabolism of the drug is independent of kidney function, that the rate of disappearance of the unchanged glipizide was approximately the same as in normals, but that the “halflife” of the metabolites was increased to 20 h and more.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0428
    Keywords: 14C-labelled glipizide ; pharmacokinetics ; pharmacodynamics ; metabolism ; protein-binding ; insulin concentration ; glucose determination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Peak serum concentrations are reached after about 2 h following oral administration of 5 mg radioactive glipizide, and in the case of intravenous administration of 1 mg radioactive substance they are reached immediately following the injection. The half-life amounts to 36 min (compartment 1) and 3.6 h (compartment 2) resp. The distribution volume of the substance is11, 100 ml. — 5 metabolites were detected in the urine; 2 of them remained unidentified; the same metabolites could partly be detected in the serum. — As regards the insulin levels, two peaks can be seen following oral as well as following intravenous administration; the first peak is reached after absorption or after the injection as the case may be, the second one is reached at midday postprandially. — Of the orally administered substance, the greatest share of total activity eliminated in the urine is observed during the first 24 h, 65.2% of the administered activity are renally eliminated during 48 h. The corresponding value for 120 h being 65.4% after oral and 64.8% after intravenous administration. — These data verify complete absorption following oral administration.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 5 (1973), S. 174-180 
    ISSN: 1432-1041
    Keywords: Tricyclic antidepressant ; nortriptyline ; metabolism ; urine ; pharmacokinetics ; twins ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The urinary excretion of nortriptyline (NT) and five of its metabolites was studied by quantitative gas chromatography in 22 twins and 7 unrelated healthy subjects after single (1 mg/kg) and multiple oral doses (0.4 mg/kg t.i.d.) of NT hydrochloride. A mean recovery of 62% of the dose was found after both single and multiple doses. The metabolite pattern in the urine was qualitatively and quantitatively identical in the two regimes, but there were marked variations in the pattern of metabolites between individuals. The disappearance rate of NT from the plasma was mainly determined by the metabolism of NT to 10-hydroxynortriptyline, which varied considerably between individuals. The data suggest that in certain rapid NT metabolizers, the upper limit for the overall clearance of NT from the plasma (if extrahepatic metabolism is assumed to be negligible) might be set by the blood flow through the liver.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 268-270 
    ISSN: 1432-1041
    Keywords: Diphenhydramine ; orphenadrine ; gas-liquid chromatography ; N-selective detector ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A method is described for the assay of nanogram quantities of diphenhydramine and orphenadrine in human plasma. The procedure employs gas-liquid chromatography and a high sensitivity nitrogen detector. It has been used to assay diphenhydramine in plasma after oral administration of therapeutic doses.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 234-238 
    ISSN: 1432-1041
    Keywords: Phenobarbital ; neonate ; maternal-fetal exchange ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Plasma concentrations of phenobarbital were measured in 18 newborn infants for one to two weeks after birth. The drug had been administered prenatally to the mothers as part of treatment for maternal hypertension or toxaemia. The plasma half-life of the drug in the infants (77–404 h) was inversely correlated with the extent of prenatal exposure to it. In three infants a bi-phasic plasma curve was found as there was a sudden change from slow to fast disappearance on the 5th to 7th day of life.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 44-53 
    ISSN: 1432-1041
    Keywords: Nortriptyline ; pharmacokinetics ; plasma clearance ; gas chromatography — mass spectrometry ; pharmacogenetics ; twins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Five identical (monozygotic) and 6 fraternal (dizygotic) sets of healthy twins between 47 and 53 years of age were given a single oral dose of nortriptyline (NT) hydrochloride 1 mg/kg. The plasma half-life, the apparent volume of distribution, and the plasma clearance of NT were estimated for each subject as well as the urinary excretion rate of conjugated and unconjugated 10-hydroxynortriptyline (10-OH-NT). “Steady-state” plasma levels predicted from the reciprocal single dose plasma clearance rate of NT agreed well with those observed in a previous study of the same twins 2 years previously. In the present study, there was a 5-fold range of the plasma half-lives and 2-fold variation in the apparent volume of distribution of NT (assuming complete availability on oral administration). No correlation was found between the plasma half-life and the apparent volume of distribution. Analysis of variance showed that most of the variability between persons in plasma half-life, apparent volume of distribution and conjugation of 10-OH-NT was genetically determined. The plasma half-life and apparent volume of distribution may contribute independently to the total interindividual variability of the “steady-state” plasma level of NT.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 181-186 
    ISSN: 1432-1041
    Keywords: Phenothiazines ; thioridazine ; serum levels ; pharmacokinetics ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The rate of absorption of thioridazine varied greatly in ten healthy volunteers who took 100 mg in the morning after an overnight fast. The peak level in blood was also variable and it was reached 1 1/4 to 4 h after dosing. Maximal concentrations in the blood varied widely from 0.13 µg/ml to 0.52 µg/ml. No relation was found between the weight or sex of the subjects and the pharmacokinetics of the drug. The serum half life of thioridazine in three healthy volunteers was 9, 10 and 10 h respectively. In a group of 22 patients receiving less than 5 mg/kg body weight a day, there was a strong correlation between the dose and the morning or evening concentration of thioridazine in the blood. A positive correlation was also observed between the age of the patient and the serum level in those who received doses of less than 5 mg/kg body weight.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 88-92 
    ISSN: 1432-1041
    Keywords: Noradrenaline pools ; 7-3H-noradrenaline ; neuro-effector junction kinetics ; pharmacokinetics ; sympathoadrenergic activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A two-compartment model of 73HNA distribution has been developed for studying sympatho-adrenergic activity in intact man. After infusion of 73HNA at constant speed in resting normal subjects, the decay curves of the plasma concentration and urinary excretion of 73HNA were plotted against time. Analysis of the curves yielded constants and indirect indications about noradrenaline exchange processes in the extracellular environment. Complete evaluation of the neuronal pools and of the pathways of biosynthesis and metabolism was impossible, but it seemed likely that 73HNA entered small neuronal pools that underwent rapid exchange with the extracellular environment, a point of some interest in clinical and pharmacologic investigations.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 137-140 
    ISSN: 1432-1041
    Keywords: Urography ; Hypaque® ; Urovist® ; pharmacokinetics ; renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Comparative tests were carried out, using a radioactive tracer method, on the pharmacokinetics of sodium and methylglucamine diatrizoate. A biological model was simulated using an analogue computer; and the rate and elimination constants, the elimination half life, and the ratio of tissue entry to tissue elimination constants were calculated. Over the period of time required for X-ray diagnosis, the two salts of the contrast medium acid which were tested did not alter the pharmacokinetics of the contrast medium itself.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 245-250 
    ISSN: 1432-1041
    Keywords: Procaine amide ; N-acetylprocaine amide ; sustained-release ; pharmacokinetics ; ventricular arrhythmia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Ten patients with acute myocardial infarction were studied during treatment with either a conventional or a new sustained-release preparation of procaine amide in order to compare fluctuations in plasma concentration and urinary excretion of the drug during “steady state” conditions. Procaine amide in plasma was measured by spectrofluorimetry and the urine concentration of it and its major metabolite, N-acetylprocaine amide, by gas chromatography. The average fluctuation of plasma concentrations was 3.5±0.1 µg/ml during treatment with sustained-release tablets (dosage interval 8 h) and 4.2±0.4 µg/ml during treatment with ordinary tablets (dosage interval 4 h), i. e. it was 20% greater during treatment with the conventional preparation. There was no difference between the two preparations in recovery of the drug from urine (sustained-release tablets 85.4±3.0%; and conventional tablets 90.3±5.4%). Thus, the new sustained-release preparation of procaine amide administered 3 times daily produced the same range of plasma levels as the identical dose of conventional tablets given 6 times a day.
    Type of Medium: Electronic Resource
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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 6 (1973), S. 261-267 
    ISSN: 1432-1041
    Keywords: Alclofenac ; antiphlogistic ; man ; pharmacokinetics ; dosage regimes ; plasma levels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A one compartment open model has been found to fit plasma concentration data previously obtained in man after single oral doses of alclofenac; the parameters of the model are: $${\text{t}}_{\tfrac{{\text{1}}}{{\text{2}}}} $$ abs=1.3±0.7h, $${\text{t}}_{\tfrac{{\text{1}}}{{\text{2}}}} $$ el=3.5±1.2h, Vd/F=17±6. The model has been used successfully to predict steady-state plasma levels of alclofenac after multiple oral doses. One treatment schedule (initial dose 500 mg, maintenance dose 250 mg five times a day) was administered to two volunteers for five days and the plasma levels of alclofenac determined daily. The latter were in good agreement with computer predictions based on the model. It is now possible, therefore, to select the most suitable dosage regimes for this drug.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 51-68 
    ISSN: 1573-8744
    Keywords: pharmacokinetics ; cancer chemotherapy ; cell kinetics ; mathematical model ; cell cycle specific drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Predictive models have been developed to simulate cancer cell populations under treatment with cytotoxic drugs, with both direct-acting and cell cycle specific drugs being considered. Models of cell growth kinetics have been combined with simple pharmacokinetic models to complete the cell-drug interaction system. The models depend on knowing the distribution of generation time in the cell population, the cell-drug interaction, and the local concentration of the drug at the effective site. All of the quantities can be obtained, in principle, from separate experiments and combined to form a model describing several aspects of the cell-drug response system.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 497-520 
    ISSN: 1573-8744
    Keywords: tissue distribution ; plasma protein binding ; tissue protein binding ; fat/water partition coefficient ; volumes of distribution ; corticosterone ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The concentration of a drug at its site of action will be affected by the ability of the drug to distribute to and pass through various membranes and tissues. Mechanisms of drug distribution are summarized in this paper and include the differences between intracellular and extracellular pH,active transport systems for drugs, distribution of drugs between fat and water in adipose tissues, the reversible binding of drugs to phospholipids and to various macromolecules including proteins, nucleic acid, and melanin. These mechanisms usually tend to decrease the concentration of unbound drugs at their sites of action, but usually not to the extent one would predict on the basis of in vitrobinding studies. The effects of drug distribution in altering the biological half-lives of drugs in the body are discussed as well as the interrelationship between the kinetic volumes of distribution for drugs and blood flow rates through the organs that eliminate these drugs. These concepts are illustrated for corticosterone levels following intravenous bolus injections and infusions into rats.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 341-361 
    ISSN: 1573-8744
    Keywords: pharmacokinetics ; pharmacokinetic models ; bioavailability ; clinical metabolic profile ; chronic dosing regimens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The present status of pharmacokinetics is reviewed. Pharmacokinetic models and the basic concepts involved in applying models to blood, urine, bile, and tissue levels of drugs and metabolites are discussed. An outline of methods for pharmacokinetic analyses is proposed. Special emphasis is given to the determination of bioavailability of a drug from various dosage forms. Uses of pharmaco-kinetics in determining sites of drug action and in determining a clinical metabolic profile are suggested. The perturbations of magnitudes of pharmacokinetic parameters among individuals challenged with the drug can be used as a diagnostic tool in evaluating the state of dynamic processes, the presence of metabolic diseases and genetic abnormalities, and the failure of physiological functions. The use of pharmacokinetics and the prediction of chronic dosing regimens are reviewed. Typical curves depicting predicted blood levels on repetitive dosing are presented.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 521-540 
    ISSN: 1573-8744
    Keywords: pharmacokinetics ; polygenically controlled disease states ; pharmacokinetic twin studies ; pharmacokinetic heritability ; ethanol ; antipyrine ; phenylbutazone ; bishydroxycoumarin.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The application of pharmacokinetics to the elucidation of polygenic factors involved in drug disposition is discussed in the context of three questions: (a)How extensive is the variation among individuals in rate of plasma clearance for commonly used drugs? (b)If appreciable variation occurs, what are the relative contributions of genetic and environmental factors to its maintenance? (c) What role is played by polygenic factors in maintaining this variation?Large variance in plasma decay rates for phenylbutazone, ethyl biscoumacetate, antipyrine, isoniazid, and nortriptyline is noted throughout the general population. However, these large variations appear to be controlled predominately by genetic rather than by environmental factors on the basis of studies run on identical and fraternal twins. At the present time, an individual's capacity to metabolize drugs and the effects of various conditions in altering that basal, genetically determined capacity seem to be best indicated by measurements of the plasma antipyrine half-life. While the theoretical advantages of obtaining blood concentrations of drugs as a guide to their more rational administration are evident, several practical problems are discussed in this paper.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 137-163 
    ISSN: 1573-8744
    Keywords: pharmacokinetics ; nonlinear regression ; drug distribution ; compartmental models ; computer program ; BASIC ; time sharing ; spectinomycin ; naloxone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract COMPT, a computer program for optimizing the solution of integral compartmental models of drug distribution by nonlinear regression analysis, is written in extended BASIC for use in time-sharing computer systems. It is based on Hartley's modification of the Gauss-Newton gradient method. The characteristics and features of the program are indicated, and the program source listing is presented. This version of COMPT is designed to solve the two-compartment open model of intravenous drug administration. Examples of the results of the operational program are presented. The program is modifiable to permit analytical solutions for other types of systems described by nonlinear equations.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 175-200 
    ISSN: 1573-8744
    Keywords: pharmacokinetics ; cancer chemotherapy ; pharmacodynamics ; cell kinetics ; vincristine ; vinblastine ; arabinosylcytosine ; cyclophosphamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A pharmacodynamic model is proposed and equations are developed for the quantitative analysis of dose-time-cell-survival curves produced by the administration of cell-cycle-specific chemo-therapeutic agents. The essential feature of the model is an irreversible, bimolecular mechanism of drug-receptor interaction which serves as the interface between the pharmacokinetics of the drug and the cell-cycle-cell-proliferation kinetics of the normal and neoplastic cells. A preliminary cell system which allows adequate characterization of the experimental data is a two-compartment model where cells are assumed to exist in their proliferative and nonproliferative phases. The chemotherapeutic model was used to analyze dose-time-cell-survival curves found in the literature for the effects of vincristine, vinblastine, arabinosylcytosine, and cyclophosphamide on lymphoma and hematopoietic cells in the mouse femur. Similarity in the values of the “cell-kill” constants for these drugs on the two cell types indicates that, in the cell systems studied, the proliferative state of the cells is the primary in vivodeterminant of selective chemotherapy.
    Type of Medium: Electronic Resource
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  • 18
    ISSN: 1573-8744
    Keywords: absorption ; amphetamine ; bioavailability ; elimination ; pharmacokinetics ; phentermine ; resin-bound drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Plasma levels of amphetamine and phentermine have been measured in man in a crossover study of the pharmacokinetics of these agents following oral administration of resin-bound and soluble salt formulations. The one-compartment open model with first-order drug absorption was fitted to the data from each subject by nonlinear regression methods and provided an excellent fit. Relative bioavailability of the two salts did not differ for either drug. In both cases the rate constant for absorption was significantly lower and less variable for the resinated compound.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 295-305 
    ISSN: 1573-8744
    Keywords: diazoxide ; pharmacokinetics ; stable-isotope dilution ; GC-mass fragmentography ; solubility ; excretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A specific, sensitive, and accurate assay for diazoxide in human plasma and urine samples was developed utilizing stable-isotope dilution-GC-mass fragmentography. 3-Trideuterodiazoxide (d 3-diazoxide) served as internal standard, and diazoxide was N-methylated with diazomethane prior to GC. Plasma elimination half-lives of diazoxide ranged within 20–53 hr in four severely hypertensive patients, which did not correlate with endogenous plasma creatinine levels. A rapid infusion over 10–15 sec of an antihypertensive dose presumably resulted in a very transient precipitation of diazoxide due to its limited solubility of approximately 380 Μg/ml plasma. Urinary excretion accounted for 4–6% of the dose within 24 hr after administration in the four patients studied and totalled 19% and 22% in two patients. Renal clearance of diazoxide was below 1 ml/min on the first day following administration and increased to 2–3 ml/min on consecutive days. It was concluded that renal excretion of diazoxide is self-limited by antihypertensive doses in severely hypertensive patients. The major route of elimination in these patients may be due to metabolism.
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  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Journal of pharmacokinetics and pharmacodynamics 1 (1973), S. 89-98 
    ISSN: 1573-8744
    Keywords: clindamycin ; clindamycin-2-palmitate ; clindamycin-2-hexadecylcarbonate ; bioavailability ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract To determine the bioavailability of clindamycin from the microbiologically inactive clindamycin-2-palmitate and clindamycin-2-hexadecylcarbonate in man, a three-way crossover study was conducted with oral administration of the two esters and clindamycin hydrochloride. In each case, serum clindamycin bioactivity concentrations were fitted to a one-compartment open model with an initial lag time. Analysis of variance of measured quantities (serum concentrations and urinary excretion) and of derived pharmacokinetic parameters showed that for every comparison except maximum serum concentrations clindamycin-2-palmitate was not significantly different (at p=0.05) from clindamycin hydrochloride. Clindamycin-2-hexadecylcarbonate gave significantly different values from those for the hydrochloride in all cases except the rate constant and half-life for elimination from the serum. The palmitate was the superior ester and was bioequivalent to the hydrochloride in man.
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  • 21
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 395-411 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The design and implementation of software for real-time spectral analysis on an IBM 1130 with 8k core is described. The procedures for estimation of coherence and cross-spectra are discussed in detail.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 22
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 381-394 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The Fast Fourier Transform is employed as a method of Laplace transform inversion to solve problems in the civil engineering fields of visco-elasticity and hydrology. When these problems are accurately represented by a linear time-invariant model, it is shown that the Fast Fourier Transform inversion procedure is often more accurate than standard convolution and inversion techniques. The speed and accuracy of solution resulting from this application of the Fast Fourier Transform is illustrated by referring to case studies solved on an IBM 1130 computer, model 3D processor with 32K memory.
    Additional Material: 13 Ill.
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  • 23
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 427-439 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Stress fields near crack tips in an elastic body can be specified by the stress intensity factors which are closely related to the stress singularities arising from the crack tips. These singularities, however, cannot be represented exactly by conventional finite element models. A new method for the analysis of stresses around cracks is proposed in this paper on the basis of the superposition of analytical and finite element solutions. This method is applied to several two-dimensional problems whose solutions are obtained analytically, and it is shown that their numerical results are in excellent agreement with analytical ones. Sufficiently accurate results can be obtained by the conventional finite element analysis with rather coarse mesh subdivision. Computational efforts are then considerably reduced compared with other methods.
    Additional Material: 8 Ill.
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  • 24
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 447-447 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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  • 25
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 454-456 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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  • 26
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 456-456 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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  • 27
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 467-473 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A generalized variational principle is presented, which leads to a modified finite element approach for three-dimensional field problems. Both, potential function and velocity field, are approximated by expansions which are continuous across the inter-element boundaries. The rapid convergence of this mixed model is shown by two examples.
    Additional Material: 7 Ill.
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  • 28
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 497-509 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A computer program for the in-core solution of large, sparse, unsymmetric systems of linear equations is presented in this paper. The program employs elimination techniques for solution of systems of linear equations. A limited number of zeros is stored and trivial arithmetic is by-passed to preserve computer storage and to reduce the time required for solution. Several techniques for selecting the pivotal elements are discussed and their effect on accuracy and computational time are examined.
    Additional Material: 1 Ill.
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  • 29
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 6 (1973), S. 521-527 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Numerical methods are used to investigate the two-dimensional motion of a viscous incompressible fluid impulsively started past a flat plate of finite breadth at zero incidence to the uniform motion of the fluid at large distances from the plate. A step by step integration in time of Helmholtz's vorticity equation is used for Reynolds numbers 10-500.The magnetohydrodynamic case is also considered with the applied magnetic field at infinity parallel to the uniform stream and the non-conducting plate. Results for the Magnetic Reynolds number 50 and infinite, Viscous Reynolds number 50 and 0≤β≤2, where β is the ratio of the square of the Alfvén speed to the square of the main stream velocity, are presented.
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  • 30
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 608-608 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 31
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 43-55 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: A new family of triangular finite elements is described, useful for solving the axisymmetric vector Helmholtz equation, and a variety of scalar Helmholtz equation problems which lead to generalized Bessel equations of some order m. This family is similar in principle to the scalar axisymmetric Helmholtz elements derived earlier, but requires both reformulation of its describing equations and corresponding new universal element matrices, for successful computational implementation. The necessary formulation is given in this paper. Matrix elements to the sixth-order inclusive have been calculated and extensively tested computationally.
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  • 32
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 57-67 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: The criteria for stability of the explicit finite difference solution of the one-dimensional, transient, conduction heat transfer problem with both radiant and convection heat transfer at the boundaries are considered in this paper. These criteria are governed by an inequality set from a functional relationship between the newly calculated and the old temperature at each node.From the node with the most stringent criteria, it is shown that setting the coefficient of the old temperature equal to zero in the governing difference equation is not sufficient for a general criterion. On the other hand, setting the derivative of the new temperature with respect to the old temperature equal to zero in the governing difference equation presents a simple, straightforward technique for obtaining a sufficient condition for a stable system. It is further shown that the second law of thermodynamics, written in explicit finite difference form, does present a necessary criterion for stability. However, the second law, because it is in the form of an inequality, does not present as simple a criterion as the derivative method does.The specific problem studied is a finite thickness slab, initially at a uniform temperature, but instantaneously subjected to both radiation and convection on its two surfaces. Temperature profiles were calculated on a digital computer and are presented in dimensionless graphical form over a range of five dimensionless parameters. A plot that relates stability to the maximum time-step size for the entire range of practical conditions of radiation numbers is also presented.
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    International Journal for Numerical Methods in Engineering 7 (1973) 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 117-124 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: A theorem expressing geometric conditions necessary and sufficient for the stiff stability of a linear multistep method is obtained. A corollary to this theorem provides sufficient conditions for stiff stability, for the class of algorithms characterized by a single essential root. By applying the Schur-Cohn criterion and employing a computerized algebraic manipulation program, the result provides a first step towards an exhaustive search technique for determining a continuum of members of this class.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 175-183 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: A method is described for the solution of large sets of sparse equations arising in structural analysis. This method, called partial elimination, combines the concepts of elimination and iteration in such a way that good convergence rates can be obtained using a computer storage space not much greater than that required for other iterative methods.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 211-223 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A survey of recent developments in sparse matrix technology is presented. Two fundamental areas are reviewed: 1.Sorting and reordering techniques by which the non-zero elements of a given sparse matrix can be rearranged to obtain a form which leads to more efficient computations.2.Direct methods for solving systems of linear equations and computing inverses.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 240-240 
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  • 38
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 155-173 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: The present investigation examines the multibar truss optimization problem in the context of a general class of unconstrained optimization procedures in conjunction with various types of penalty function transformations. Specifically, the problem is transformed into a series of unconstrained minimization problems using the penalty function techniques of Heaviside and SUMT. These are solved using the methods of Rosenbrock (orthogonal directions), Powell (conjugate directions) and Nelder-Mead (Simplex). This resulted in many cases in substantial improvements being recorded over previously reported data. The paper includes a comparative study of the synthesis based on these procedures.
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  • 39
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 461-477 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: Computer-oriented mesh generators, which serve as pre-processors to finite element programs, have recently been developed by several investigators to alleviate the frustration and to reduce the amount of time involved in the tedious manual subdividing of a complex structure into finite elements. Our purpose here is to describe how the techniques of bivariate ‘blending-function’ interpolation, which were originally developed for, and applied to, geometric problems of computer-aided design and numerically controlled machining of free-form surfaces such as automobile exterior panels, can be adapted and applied to the problems of mesh generation for finite element analyses. We concentrate attention on the problem of curvilinearly co-ordinating simply connected planar domains R by constructing invertible maps of the unit square S ≡[0, 1] × [0, 1] onto R. Extensions of the methods described herein to shells in 3-space is straightforward and is illustrated by a practical example taken from the automobile industry. Analogous mesh generators for three-dimensional solids can be developed on the basis of the trivariate ‘blending-function’ formulae found at the end of the second section.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 309-323 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: Various solutions of laminated plates by the finite element method are analysed. An efficient solution of skew (or rectangular) laminated plates with small effect of σz and ∊z stress and strain components is developed. It can be used with an arbitrary number of layer elements (sub-elements) in different plate elements. Some remarks to the possible modification of solution are presented. Numerical examples with a short discussion and conclusions complete the paper.
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    Notes: The hybrid-element concept and the complex variable technique have been adopted for constructing a special super-element to be used jointly with conventional finite elements for the analysis of elastic stress intensity factors for plane cracks. The use of the complex variable technique permits the proper consideration of the stress intensity at the crack tip, and it also leads to very efficient programming. The use of such a super-element in the finite element solution has been shown to be highly accurate when only a very coarse element mesh is used near the crack.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 345-355 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: Consider a solid heat conductor with a non-linear constitutive equation for the heat flux. If the material is anisotropic and inhomogeneous, the heat conduction equation to be satisfied by the temperature field θ(x, t) is, \documentclass{article}\pagestyle{empty}\begin{document}$$ \rho c\frac{{\partial \theta }}{{\partial t}} = {\rm div}({\rm L}(\theta,{\rm x})[{\rm grad}\theta]) + q $$\end{document} Here L(θ, x) [grad θ] is a vector-valued function of θ, x, grad θ which is linear in grad θ, In the present paper, the application of the finite element method to the solution of this class of problems is demonstrated. General discrete models are developed which enable approximate solutions to be obtained for arbitrary three-dimensional regions and the following boundary and initial conditions: (a) prescribed surface temperature, (b) prescribed heat flux at the surface and (c) linear heat transfer at the surface. Numerical examples involve a homogeneous solid with a dimensionless temperature-diffusivity curve of the form κ = κ0(l + σT). The resulting system of non-linear differential equations is integrated numerically.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 405-408 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: Several formulas are presented for the numerical integration of a function over a triangular area. The formulas are of the Gaussian type and are fully symmetric with respect to the three vertices of the triangle.
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  • 44
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 413-425 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: A limitation of most plate and shell discrete elements now in use is the shape of their undeformed geometry. Typically, the plan form of these elements is a straight-sided triangle or quadrilateral that linearly approximates the undeformed geometry while often using higher-order polynomials to approximate the deformed geometry. This modelling difference leads to inefficiencies that can be eliminated, as demonstrated by a new parametric discrete element based entirely on bicubic Hermite polynomials. This representation of element geometry corresponds to the bicubic Coon's surface patch widely used in design, which allows a common mathematical model for design and analysis. Consideration is given to automating the generation of these patches. Solutions are presented for several plate bending and plate stretching problems. The solutions are in good agreement with closed-form solutions and photoelastic results in the case of a stress-concentration problem. These data demonstrate that the new parametric discrete element maintains solution accuracy for plates with curved boundaries.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 443-446 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: This paper compares the results obtained by the finite element method with ‘exact’ solutions to a given set of problems. These are the stresses on the boundary of a hole in an infinite plate, the plate being subjected to three different types of loading. Two types of element are used for these plane stress problems, triangular elements with constant strains and tri- angular elements with linearly varying strains. The problems are solved for two different meshes and the results shown are stresses along a radial section and the values derived for stress concentrations against the number of unknowns in each mesh.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 446-447 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 450-451 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 456-456 
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  • 49
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 459-466 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: This paper is concerned with developments in mathematical modelling of turbo-generator units for use in the dynamic analysis of electrical power systems. Emphasis is placed on an over-all reduction in computing time, whilst retaining a high order of accuracy of transient response. Accurate linear models are then derived and provide an alternative to the piecemeal formulations hitherto employed in small signal analysis. These equations form a practical basis for the synthesis of optimal control systems for large alternators.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 475-487 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: An essential feature of finite element methods of analysis for symmetrically loaded shells of revolution is the setting up of equations representing the response of a short ‘ring’ element to edge loading.In this paper the axisymmetric behaviour of a short elastic cylindrical shell element under edge loading is described in a new way by means of a matrix which is a combination of stiffness, flexibility and ‘neutral’ sub-matrices. The coefficients of the matrix are derived direct from the equations of the problem, which involves a trivial amount of work in comparison with conventional methods.The corresponding matrix for a short section of an arbitrary shell of revolution is set up with little additional effort, and its use is described for calculation of edge response coefficients for portions of spherical shells.Finally, the method is used to study by iteration the behaviour of a thin spherical shell of viscous material containing a rigid boss which is loaded radially inwards: changes in meridional profile are followed as deformation proceeds. Results are presented for both linear and non-linear viscous material.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 511-519 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: The matrix eigenvalue problem Hui = λi ui is considered. It is shown that when a new approximate vector v(n+1) to u1 (the eigenvector of the lowest eigenvalue) is computed from the present one v(n) by the relation v(n+1) = (1- αH + βH2) v(n) or v(n+1) = (1- αH + βH2 - γH3) v(n), the convergence rate is at least double that of the gradient method which corresponds to set β = γ = 0. Moreover, by choosing parameters α, β, or γ properly, one can get about three to five times faster convergence rate than that of the latter method, for H having very small γ2-γ1 and very large λN (the largest eigenvalue), further modifications are suggested. The relation with the Richardson method is also discussed.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 553-563 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: Three sector elements, two for plane stress problems (PSL and PSN) and one for plate bending problems (BSN), have been developed. Of the three elements, two are based on the natural mode technique. The elements have been applied to typical problems to test their performance.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 577-585 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: The one-dimensional diffusion-convection equation is formulated with the finite element representation employing the Galerkin approach. A linear shape function and two-dimensional triangular and rectangular elements in space and time were used in solving the problem. The results are compared with finite difference solutions as well as the exact solution. As another example, the convective term is set equal to zero and these techniques are applied to the resulting heat equation and similar comparisons are made.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 595-598 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 602-602 
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 94-98 
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 98-100 
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 125-136 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: The problem of optimizing the prestressing force and the tendon configuration for an indeterminate prestressed structure with prescribed cross-sectional dimensions is formulated in linear programming form, The structure is subjected to multiple load conditions and constraints are related to the structural behaviour and to the tendon configuration.It is shown that the number of behaviour constraints at each point in the structure can be reduced, as they represent parallel hyperplanes in the design space. Necessary conditions for feasible solutions are derived. The method based on transformation of the design variables, is suitable for beams, frames, grids and plates. Its application is illustrated for the case of a prestressed bridge.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 242-242 
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 287-295 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: This paper presents a triangular finite element for the solution of two-dimensional field problems in orthotropic media. The element has nine degrees of freedom, these being the potential and its two derivatives at each node.The ‘stiffness’ matrix is derived analytically so that no further integration is required when computations are performed using the element.The results obtained using the element are compared with the exact mathematical solution of both a temperature distribution and a torsion problem.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 273-286 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: In using the finite element method to compute a transient response, two choices must be made. First, some form of mass matrix must be decided upon. Either the consistent mass matrix prescribed by the finite element method can be employed or some form of diagonal mass matrix may be introduced. Secondly, some particular time integration procedure must be adopted. The procedures available divide themselves into two classes: the conditionally stable explicit schemes and the unconditionally or conditionally stable implicit schemes. The choices should be guided by both economy and accuracy. Using exact discrete solutions compared to the exact solutions of the differential equations, the results of these choices are displayed. Concrete examples of well-matched methods, as well as ill-matched methods, are identified and demonstrated. In particular, the diagonal mass matrix and the explicit central difference time integration method are shown to be a good combination in terms of accuracy and economy.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 337-344 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: A curved cubic triangular element which has as nodal parameters the value of the function and its two derivatives is derived by use of a transformation similar to that used for quadrilateral isoparametric elements. A special form of the element which may be used to satisfy the condition that the function is constant along a boundary is also presented.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 137-154 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: This paper shows how analytic surfaces can be used to define the vanes of an impeller of a centrifugal compressor. The analysis has been given of a cubic-linear patch for representing three-dimensional geometries. An example has shown how this type of patch can be successfully used to model the geometry of centrifugal or mixed flow impellers having 'swept back vanes at the outlet.The analysis has been programmed for the Atlas computer at the Computer Aided Design Centre (CADC), Cambridge and set up in such a way that the designer can examine systematically a range of impeller shapes.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 185-194 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: The method of lowering the order of a matrix equation which describes the dynamics of a finite element model is presented. The finite element with a ‘truncated’ mass matrix is obtained for calculating thin plate vibrations. Such an element has one vibrational degree of freedom at each nodal point. In the case of uniform systems the accuracy provided by the suggested element is no less than that provided by the non-conforming elements, which have three vibrational degrees of freedom at each nodal point, and in some cases it is greater. The finite elements with a ‘truncated’ mass matrix have essential advantages in the study of non-uniform systems.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 395-400 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: An outline is given of a method for dealing with curved boundaries in finite difference calculations (relaxation or other similar techniques) where the gradient normal to the boundary is specified. Fluid flow calculations using the velocity potential are typical of such problems and the flow round a circular cylinder is computed as an example. The method makes no approximation which is not made in the usual finite difference techniques, therefore accuracy at the boundary is as good as in the remainder of the field.
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  • 66
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 410-410 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 67
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    International Journal for Numerical Methods in Engineering 7 (1973) 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 68
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 255-271 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A finite element method is presented for the transient analysis of large-displacement, small-strain problems with material non-linearities. The method employs a convected co-ordinate technique and a direct nodal force computational scheme of considerable efficiency. Detailed formulations are given for a plane, constant strain triangular element and a Euler-Bernoulli beam element. Results are presented for several example problems and compared with experimental data and other numerical solutions.
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  • 69
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 554-556 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 70
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 560-563 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 71
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 566-568 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 72
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    International Journal for Numerical Methods in Engineering 6 (1973) 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 73
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    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 74
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 543-552 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A relationship is developed between mass condensation and simultaneous iteration when used to determine the natural frequencies and vibration modes of large structural systems. A significant factor in the comparison between the methods is the extra versatility and reliability of simultaneous iteration.
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  • 75
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 565-576 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Interpolation techniques are reviewed in the context of the approximation of the solution of boundary value problems. From the variational formulation, the approximation error norm is related to the interpolation error norm.Among global interpolation techniques, bicubic splines and spline-blended are reviewed; among local, Hermite's and ‘serendipity’ polynomials. The corresponding interpolation error norms are computed numerically on two test functions. The methods are compared for accuracy and for number of operations required in the solution of boundary value problems. The conclusion is that spline interpolation is most convenient for regular hyper-elements, while high precision finite elements become convenient for very fine or irregular partition.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 591-594 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 77
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 601-602 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 78
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 606-607 
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    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 79
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 529-542 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: For one-, two- and three-dimensional co-ordinate systems finite element matrices for the wave or Helmholtz equation are used to produce a single difference equation holding at any point of a regular mesh. Under homogeneous Dirichlet or Neumann boundary conditions, these equations are solved exactly. The eigenfunctions are the discrete form of sine or cosine functions and the eigenvalues are shown to be in error by a term of + O(h2n) where n is the order of the polynomial approximation of the wave function. The solutions provide the means of testing computer programs against the exact solutions and allow comparison with other difference schemes.
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  • 80
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 587-591 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The finite element method provides a powerful new instrument in the solving of problems of flow in the subsoil by means of a numerical processor. This new technique may be reinforced, without complicating its numerical aspect, by an appropriate choice of the sub-regions into which the original region is divided.In two-dimensional confined flows particular types of triangular meshes may be adopted which ensure the final matrices to be diagonally dominant both in steady-state and transient conditions, in heterogeneous and anisotropic fields. This will allow the utilization of rapidly converging iterative processes in the solution of the final linear systems with a notable saving of processing time.
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 598-601 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 82
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 603-606 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 83
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 608-608 
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  • 84
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 1-15 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Turbulent boundary-layer flows of non-reacting gases are predicted for both internal (nozzle) and external flows. Effects of favourable pressure gradients on two eddy viscosity models were studied in rocket and hypervelocity wind tunnel flows. Nozzle flows of equilibrium air with stagnation temperatures up to 10,000°K were computed. Predictions of equilibrium nitrogen flows through hypervelocity nozzles were compared with experimental data. A slender spherically blunted cone was studied at 70,000 ft altitude and 19,000 ft/sec in the earth's atmosphere. Comparisons with available experimental data showed good agreement. A computer program was developed and fully documented during this investigation for use by interested individuals.
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  • 85
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 69-83 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A convergence technique for use with the streamline curvature method of cascade and channel flow is presented which produces stable and rapid convergence for subsonic, transonic and supersonic flow and also in the downstream region where the Kutta-Joukowski condition is applied to a cascade flow. The convergence method is fully two-dimensional in nature, the iterative changes being determined via a model which takes into account the actual streamwise error distribution and the real normal changes in the grid.
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  • 86
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    International Journal for Numerical Methods in Engineering 6 (1973), S. 607-608 
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  • 87
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    International Journal for Numerical Methods in Engineering 7 (1973) 
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  • 88
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    Notes: This article presents an efficient and numerically stable algorithm, along with a complete listing of the associated computer program, developed for the accurate computation of specified roots and associated vectors of the eigenvalue problem Aq = λBq with band symmetric A and B, B being also positive definite. The desired roots are first isolated by the Sturm sequence procedure; then a special variant of the inverse iteration technique is applied for the individual determination of each root along with its vector. The algorithm fully exploits the banded form of relevant matrices, and the associated program written in FORTRAN V for the JPL UNIVAC 1108 computer proves to be most significantly economical in comparison to similar existing procedures.The program may be conveniently utilized for the efficient solution of practical engineering problems including free vibration and buckling analysis of structures. Results of such analyses are presented for representative structures.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 85-93 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: It is well known that the finite element method leads to large square symmetric matrices which are highly banded. Even if only the half bandwidth is stored it is easy to saturate the computer storage; this is because the half bandwidth contains a large amount of zeros. This paper discusses an alternative approach where a small rectangular section of the full bandwidth is stored, this method leading to a significant reduction in storage requirements.
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  • 90
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 103-116 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The numerical solution of non-linear diffusion problems is considered from the computational view- point. The advantage of various aspects of the problem solution are considered toward enhancing the computational understanding of the system. First is the analytical solution to the reduced linear case which acts as an error check on the numerical solutions as well as providing a base for a perturbation theory approach. Next are two different numerical solutions which are utilized to generate solution redundancy. These are based upon the method of differential quadrature and the method of finite differences.The application to non-linear transient slab diffusion with a general reservoir boundary condition is shown as an example of the various methods.
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  • 91
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 357-378 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A procedure is described for solving plane strain rigid perfect-plasticity problems which lead to linear integral equations. The problem of finding the initial characteristic (slip-line), from which the complete field can be constructed, is reduced to a simple matrix inversion. Although the form of this matrix will depend on the particular problem concerned, it will be expressible in terms of a few fundamental matrices which occur in all problems of this type. The properties of these basic matrices and FORTRAN subroutines for assimilating them and for performing the corresponding linear transformations are given in detail. In illustration the procedure is applied to a drawing and to a strip rolling problem.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 325-336 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The Kantorovich theorem is virtually the only known sufficiency condition for convergence of Newton's method on a set of non-linear equations. The theorem gives very conservative bounds and is difficult to apply. In this paper the power system load flow problem is solved by Newton's method, and a sufficiency condition for the convergence of the iterations on this particular problem is given. The criterion relates to a condition number defined on the Jacobian matrix associated with the non-linear equations. Computational feasibility is considered and the merits of its use are discussed.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 379-394 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 227-228 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 95
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 228-232 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Mr. Bruce Irons recently1 proposed a modification of the Conjugate Gradient Method. This note shows that if the matrix of the original set of equations is symmetric this method will have the same terminal property as the usual Conjugate Gradient Method except for a particular case when it will not converge at all. If the matrix is not symmetric we cannot deduce the usual terminal property.
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    International Journal for Numerical Methods in Engineering 7 (1973) 
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  • 97
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 441-459 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Based on a variational principle due to Gurtin, for linear elastodynamics, a finite element method in terms of stresses is developed for wave propagation problems. The finite element equations are simultaneous integral equations in time, with the peculiarity that they are equivalent to simultaneous linear differential equations with zero initial conditions. Written as differential equations, the finite element equations are of the form \documentclass{article}\pagestyle{empty}\begin{document}$$ [H]\{ s\} + [Q]\{ \mathop s\limits^{..} \} = \{ q(t)\} $$\end{document} where [H] is a symmetric positive-semidefinite matrix, [Q] is a symmetric positive-definite matrix and the stresses are represented by {s̈}. This is, of course, the same form as the equations for the displacement formulation.As a demonstration of the validity of the formulation numerical results are compared with a solution for a triangular-shaped strip load applied to an elastic half-space as a ramp function of time. This solution is obtained by numerical integration of the exact solution for Lamb's problem of a line load suddenly applied to a half-space. The agreement is found to be generally very good. As a further example, the case of a plate subject to uniform tension on two ends and containing a hole in the centre is presented. The results are found to be reasonable in that the characteristic stress concentration occurs near the hole, and away from the hole the results are similar to the solution for an infinitely wide plate.
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    Source: Wiley InterScience Backfile Collection 1832-2000
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    Notes: This paper describes an efficient numerical algorithm for the accurate computation of specific eigenvalues and related vectors of spinning structures. The Sturm sequence technique is first applied to isolate the required roots, which are then individually located by an inverse iteration technique adopting an efficient matrix formulation specially developed for this purpose. The associated digital computer procedure is numerically stable, which also fully exploits the banded form of relevant matrices. Furthermore, the algorithm proves to be much faster than other related existing procedures.A computer program, based on the current algorithm, has been developed in FORTRAN V for the JPL UNIVAC 1108 computer. Numerical results for representative structures, computed by the program, are also presented in detail. Extensive applications of the program are envisaged in the attitude control of spacecraft and in the natural frequency analysis of spinning structures, discretized by the finite element method.
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 553-554 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    International Journal for Numerical Methods in Engineering 7 (1973), S. 568-570 
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    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
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    Additional Material: 1 Ill.
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