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  • 1980-1984  (4,935)
  • Analytical Chemistry and Spectroscopy  (4,318)
  • Rat  (616)
  • Nuclear reactions
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Years
Year
Keywords
  • 101
    Electronic Resource
    Electronic Resource
    Effects of carbamazepine and anti-depressant drugs on endogenous catecholamine levels in the cerebroventricular compartment of the rat (1984)
    Springer
    Psychopharmacology 83 (1984), S. 169-171 
    Details
    ISSN: 1432-2072
    Keywords: Catecholamines ; Cerebroventricular perfusion ; Carbamazepine ; Imipramine ; Desmethylimipramine ; Tranylcypromine ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Concentrations of endogenous norepinephrine, dopamine and epinephrine in cerebroventricular perfusates were used to evaluate the effects of drugs on the availability of extracellular catecholamines in the intact rat brain. Administration of the antidepressant drugs imipramine, desmethylimipramine or tranylcypromine resulted in marked increases of both norepinephrine and dopamine concentrations while epinephrine levels were not affected. Treatment with a similar dose of carbamazepine — an anticonvulsant drug with antidepressant activity — resulted in a significant increase in dopamine concentrations without apparent effect on either norepinephrine or epinephrine. It is suggested that at the applied dose, carbamazepine may act to modify the uptake, release or metabolism of dopamine in brain areas adjacent to the cerebroventricular space without affecting the other catecholamines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00429729
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  • 102
    Electronic Resource
    Electronic Resource
    DNA methylation in maternal, fetal and neonatal rat tissues following perinatal administration of procarbazine (1984)
    Springer
    Journal of cancer research and clinical oncology 108 (1984), S. 56-59 
    Details
    ISSN: 1432-1335
    Keywords: DNA methylation ; Rat ; Procarbazine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cytostatic drug procarbazine has previously been shown to be a potent transplacental neurotropic carcinogen in rats. Following a single IP administration of (14C-methylprocarbazine (110 mg/kg) on day 22 of gestation, methylation products with cellular DNA were determined in fetal and maternal rat organs. The concentration of the major adduct N7-methylguanine was highest in the maternal liver (224 μmol/mol guanine). Fetal and nonhepatic maternal tissues exhibited significantly lower levels, but differed little from each other. In brain, lung, intestines, and placenta the O 6-methylguanine/N7-methylguanine ratio was close to 0.11, indicating that procarbazine, like other methylating carcinogens, initiates malignant transformation via methyldiazonium hydroxide as the ultimate reactant. Following a single dose of (14C-methyl)procarbazine to newborn animals, methylpurine values were 30–60 times lower than after prenatal administration. This suggests that DNA alkylation in nonhepatic tissues occurs by systemic distribution of a proximate carcinogen formed in the adult rat liver.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00390973
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  • 103
    Electronic Resource
    Electronic Resource
    Tumors of the nasal cavities induced in rats by 2,2-dioxopropyl-N-Propylnitrosamine (1984)
    Springer
    Journal of cancer research and clinical oncology 108 (1984), S. 114-120 
    Details
    ISSN: 1432-1335
    Keywords: Nasal cavities ; Rat ; DOPN
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Weekly SC administration of 2,2-dioxopropylnitosamine to 88 Sprague-Dawley rats resulted in the induction of 76 separate neoplasms in the respiratory region of the nasal cavities. No tumors of the olfactory region were found. Histologically there were 37 squamous papillomas, 17 transitional papillomas, and 22 squamous cell carcinomas. These tumors were compared with a selected group of 53 related human tumors of the nasal and paranasal cavities, consisting of 11 squamous cell papillomas, 13 transitional papillomas, and 29 squamous cell carcinomas. While the experimental squamous cell papillomas showed a striking histological resemblance with the squamous papillomas observed in man, none of the experimental transitional papillomas had evidence of the characteristics inverted pattern seen in humans: nevertheless, the experimental tumors showed signs of incomplete squamous metaplasia and preservation of intraepithelial secretory glands, features commonly seen in transitional papillomas of man. The squamous cell carcinomas of this experiment were very similar to the corresponding human tumors in morphology and sex incidence. In both species a significant number of squamous cell carcinomas were keretinizing and of a high grade of histological malignancy. In addition, 69% of the human squamous cell carcinomas occurred in the male sex, and 72% of the experimental carcinomas developed in males. This comparative study suggests that further studies investigating the significance of nitrosamines as suspected etiologic factors of nasal carcinogenesis in man may be useful.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00390982
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  • 104
    Electronic Resource
    Electronic Resource
    Cerebellar histogenesis and synaptic maturation following pre- and postnatal alcohol administration (1984)
    Springer
    Acta neuropathologica 63 (1984), S. 57-65 
    Details
    ISSN: 1432-0533
    Keywords: Fetal alcohol syndrome ; Rat ; Cerebellum ; Purkinje cells ; Synaptic maturation ; Metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fetal alcohol syndrome was produced in rats by feeding an ethanol-enriched, vitamine-supplemented liquid diet over a period of 4 weeks before mating and throughout pregnancy. The amount of ethanol was equivalent to 38–40% of the daily calories; control animals were fed an isocaloric amount of sucrose. The offspring of experimental animals displayed a diminished birth weight. In contrast to previous experiments, the ethanol diet was also administered during the lactating period. On postnatal day 7, experimental animals and controls were killed by perfusion and the cerebella prepared for electron microscopy. Morphometric analysis showed a reduced number of Purkinje cells. On day 12, Purkinje cells of experimental animals displayed ultrastructurally fewer organelles. Furthermore, a delayed synaptogenesis in the molecular layer was demonstrated with osmiumzinc iodide and ethanolic phosphotungstic acid showing an immature appearance of the presynaptic grid and weaker stained synaptic cleft material. The following discussion deals with possible mechanisms underlying these alcohol-induced alterations of cerebellar synaptogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688471
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  • 105
    Electronic Resource
    Electronic Resource
    Microvascular permeability in induced astrocytomas and peritumor neuropil of rat brain (1984)
    Springer
    Acta neuropathologica 64 (1984), S. 192-202 
    Details
    ISSN: 1432-0533
    Keywords: Astrocytoma ; Blood-brain barrier ; HVEM ; Transendothelial channels ; Protein tracer ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Brain tumors, benign and malignant, are characteristically more permeable to various types of tracer molecules than the neuropil in which they are embedded. Impermeability of brain neuropil capillaries is imparted by the blood-brain barrier, the anatomic basis of which is the network of interendothelial zonulae occludentes that seal capillary endothelial cells. To explore both the vascular elements of brain neoplasms and the route of tracer extravasation from them, as well as the possible effects of brain tumors on the permeability of peritumoral neuropil capillaries, brain tumors were induced in newborn Wistar rats by intracerebral (i.c.) injection of C-6 astrocytoma cells. The protein tracer horseradish peroxidase (HRP) was injected systemically into both normal and tumorbearing rats to mark the pathway along which it flowed into the tumor parenchyma tissue spaces, and to signal any concomitant tracer loss from the tumor extracellular compartment or peritumoral brain capillaries, into the neuropil extracellular milieu. Electron-microscopic examination on thin plastic sections of tumor and peritumoral neuropil revealed massive extravasation of tracer into the tumor tissue spaces, but none was seen outside of the capillaries in the surrounding brain neuropil. Zonulae occludentes of both tumor capillary endothelium and brain capillary endothelium were devoid of tracer and judged tight (sealed). Tracer was seen in pinocytotic vesicles in the highly attenuated endothelium of tumor capillaries and also in cytoplasmic vesicles within the tumor cells. The peritumoral and contralateral neuropil capillary endothelium exhibited reaction product-filled pinocytotic vesicles and vesiculo-tubular conduits. Often, one end of a HRP-filled vesiculo-tubular channel appeared continuous with either the luminal or abluminal plasmalemma. High-voltage electron microscopy of these conduits often showed them to be continuous with both luminal and abluminal surfaces of the endothelium, thus forming a continuum across the capillary wall. In addition, these transendothelial channels, clearly constituted as chains of fused vesicles, were often seen in close proximity to, or fused with, dense bodies in the endothelial cytoplasm. In spite of the presence of HRP-filled structures in the peritumoral neuropil capillary endothelium of tumor-bearing rats, no evidence of tracer extravasation from these vessels was apparent. These results suggest that although peritumoral and contralateral neuropil capillaries possess the machinery for extravasation of tracer, likely as a response to the presence of the neoplasm, tracer is not lost but, instead, is degraded by endothelial enzymes. The extensive flooding of the tumor extracellular compartment with tracer may be achieved by transport of HRP across the very thin walls of tumor capillaries by single cytoplasmic vesicles which structurally and functionally play the role of transendothelial channels. Based on the results of this study, it is unlikely that molecules delivered systemically to treat brain neoplasms, will leak into the peritumor or contralateral neuropil, either from their own capillaries, or from the extracellular compartment of the tumor parenchyma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688109
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  • 106
    Electronic Resource
    Electronic Resource
    Vulnerability to lead in protein-deprived suckling rats (1984)
    Springer
    Acta neuropathologica 62 (1984), S. 276-283 
    Details
    ISSN: 1432-0533
    Keywords: Rat ; Brain ; Lead intoxication ; Protein deprivation ; Growth and development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Most studies on lead toxicity in the suckling rat have been performed with doses leading to growth retardation. In a previous paper (Sundström et al. 1983), the effects of different lead doses on normal suckling rats were described. The dose of 10 mg/kg body weight daily given on days 1–15 pp produced minute hemorrhagic lesions on day 15 in the cerebellum, whereas rats given 5 mg/kg body weight daily lacked microscopically discernible pathologic changes in the brain. None of these groups exhibited growth retardation. To further elucidate the association between lead encephalopathy and malnutrition, lead was administered to protein-deprived suckling rats. Protein deprivation was achieved by a diet with 50% reduction of protein content. The móthers of the pups were fed this diet from 2 weeks before conception throughout the experiment. Experimental animals were injected i.p. with 5 mg or 10 mg lead nitrate/kg b.wt. daily. Littermates, injected with vehicle without lead nitrate served as controls. Protein-deprived rats without either treatment were “external” controls. Animals were killed at 10, 15, and 20 days age for determination of lead content in blood and brain and for light-microscopic examination. The protein-deprived rats given 10 mg/kg b.wt. daily were growth-retarded as compared to unexposed protein-deprived rats. The mortality was almost 100% at 15–20 days pp. At 15 days, the cerebellum of these rats showed abundant hemorrhages, and the cerebrum was also hemorrhagically discolored. Protein-deprived rats given 5 mg/kg b.wt. daily did not differ significantly from unexposed protein-deprived rats with regard to body weight gain. They presented a mortality of about 20% on days 15–20. At 15 days, cerebellar hemorrhages were a regular finding, though not as devastating as in the animals given 10 mg lead nitrate/kg b.wt. daily. The results imply an increased vulnerability to lead in protein-deprived rats as compared to normal rats. The severe encephalopathy in protein-deprived rats was associated with higher blood lead levels than in normal rats exposed to an equivalent lead burden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687609
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  • 107
    Electronic Resource
    Electronic Resource
    Delayed neuronal death in the rat hippocampus following transient forebrain ischemia (1984)
    Springer
    Acta neuropathologica 64 (1984), S. 139-147 
    Details
    ISSN: 1432-0533
    Keywords: Cerebral ischemia ; Cell death ; Endoplasmic reticulum ; Hippocampus ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An unusual, slowly progressing neuronal damage has been reported to occur in the gerbil hippocampus following ischemia (Kirino 1982). Delayed neuronal death following ischemia has also been noticed in the rat four-vessel occlusion model (Pulsinelli et al. 1982). By light microscopy this slow neuronal injury in the rat was not different from the previously known neuronal ischemic cell change. This report lead us to the question as to whether neurons in the rat hippocampus are damaged rapidly following an initial latent period or deteriorate slowly and progressively until they display overt changes. To clarify this point, observation was done on the hippocampal CA1 sector of the rat following ischemia. Rats were subjected to four-vessel occlusion, and those which developed ischemic symptoms were perfusion-fixed. Although the change appeared very slowly and lacked microvacuolation of the cytoplasm, neuronal alteration was practically not different from classical ischemic cell change. By electron microscopy, however, the change was detectable when the neurons still appeared intact by light microscopy. An increase in the membranous organelles and deposition of dark substances were the initial manifestations. It seemed that the CA1 neurons deteriorated very slowly and progressively, and that they retained partial viability in the initial phase of the change. In spite of the difference in light-microscopic findings, the mechanisms underlying delayed neuronal death in the rat and gerbil hippocampus seemed to be identical.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00695577
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  • 108
    Electronic Resource
    Electronic Resource
    Structure-activity relationship of stress-inducing odorants in the rat (1984)
    Springer
    Journal of chemical ecology 10 (1984), S. 1007-1018 
    Details
    ISSN: 1573-1561
    Keywords: Rat ; Rattus norvegicus sp. ; odorants ; stress ; behavior ; open field ; corticosterone ; fox dropping ; ketone ; sulfur ; compounds ; tans ; mercaptoketones ; repellent ; structure-activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The stress for 12 sulfur-containing synthetized volatiles was evaluated in male Wistar rats and compared to that for fox-dropping extract concentrate. Stress behavior was analyzed by quantifying various stress responses in a standard open field and measuring the increase in plasma corticosterone concentration. Nine compounds induced stress—a dihydrothiazole, two cyclic polysulfides, five mercaptoketones, and a mercaptan. For the mercaptoketones, the following structure-activity relationships were observed. Size can vary considerably; the mercapto group can be either alpha or beta and either secondary or tertiary. The keto group is not essential, since a structurally related mercaptan remains active. The mercapto group is essential for activity in mercaptoketones, since conversion to a methyl sulfide resulted in a neutral response. This type of odorant could function as an allomone and may have potential in rat control as an area repellent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00987509
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  • 109
    Electronic Resource
    Electronic Resource
    Wirkung der lokalen moderaten Hyperthermie in Kombination mit N-Nitroso-1,3-bis-(2-chlorethyl)-harnstoff (BCNU) und 5-Fluor-(tetrahydro-2-furyl)-uracil (Ftorafur) auf induzierte autochthone Coloncarcinome der Ratte (1984)
    Springer
    Langenbeck's archives of surgery 363 (1984), S. 5-15 
    Details
    ISSN: 1435-2451
    Keywords: Hyperthermia ; Induced colonic carcinoma ; Rat ; Chemotherapy ; BCNU ; Ftorafur
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Hyperthermie zur Behandlung von Tumoren wird seit längerem in In-vitro- und In-vivo-Versuchen und auch in der Klinik in verschiedenen Anwendungsformen erprobt. Bei der Kombination von Hyperthermie mit Chemotherapie wird eine überadditive cytostatische Wirkung beschrieben. In einem klinisch orientierten, kontrolliert durchgeführten Tierversuch wurde an einem durch N-Nitrosoacetoxymethylmethylamin (AMMN) induzierten autochthonen Coloncarcinom bei Sprague-Dawley-Ratten eine lokale, moderate Hyperthermie (43,5°C, 3 × 60 min) und eine Kombinationsbehandlung von Hyperthermie und Polychemotherapie (BCNU und Ftorafur) durchgeführt unter endoskopischer Diagnosestellung und Verlaufskontrolle. Es konnte keine Überlebenszeitverlängerung durch die angewendeten Therapien und keine additive Wirkung der lokalen moderaten Hyperthermie in Kombination mit der Chemotherapie bei diesem „harten”, d. h. relativ chemotherapieresistenten, Tumormodell gesehen werden.
    Notes: Summary The use of hyperthermia for the treatment of tumors has been tested in in vitro and in vivo experiments as well as clinically for a long time. Combination of hyperthermia with chemotherapy was reported to result in overadditive cytostatic effects. In a clinically adapted, controlled animal experiment, local moderate hyperthermia (43.5°C, 3 × 60 min) alone and in combination with polychemotherapy (BCNU and Ftorafur) was used for the treatment of AMMN-(N-nitrosoacetoxymethyl-methylamine) induced autochthonous colonic carcinomas in Sprague-Dawley rats. Diagnosis and follow-up inspections were carried out endoscopically. The applied therapies did not result in prolonged survival times, nor was an additive effect seen after combined hyperthermia and chemotherapy in this “hard”, i. e. relatively chemotherapy-resistent, tumor model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01255773
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  • 110
    Electronic Resource
    Electronic Resource
    Wirkung der lokalen moderaten Hyperthermie in Kombination mit einer Chemotherapie durch N-Nitroso-1,3-bis-(2-chloroethyl)-harnstoff (BCNU) auf das in das Colon descendens der Ratte transplantierte Yoshida-Sarkom (1984)
    Springer
    Langenbeck's archives of surgery 362 (1984), S. 253-261 
    Details
    ISSN: 1435-2451
    Keywords: Hyperthermia ; Yoshida sarcoma ; Chemotherapy ; BCNU ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Hyperthermie zur Cytostase von Malignomen ist in zahlreichen In-vitro- und In-vivo-Untersuchungen beschrieben worden. Die Kombination von Chemotherapie mit Hyperthermie soll zur Potenzierung der therapeutischen Wirkung führen. Ein Forschungsgegenstand ist der zeitliche Abstand zwischen beiden Therapiemodalitäten. Anhand eines Yoshida-ColonModells bei Sprague-Dawley-Ratten wurde eine lokale Hyperthermie (43°C, 60 min) im Abstand von 0, 3, 6, 9, 12 und 24 h nach einer Chemotherapie mit BCNU durchgeführt. Die Ergebnisse zeigten keine signifikante Steigerung der Heilungsrate durch die Hyperthermie. Angesichts unserer Ergebnisse sollten z.B. die mit groben Hoffnungen propagierten hyperthermen Peritoneallavagen erst im Tierexperiment einer kontrollierten Untersuchung unterzogen werden.
    Notes: Summary There are numerous reports on in vitro and in vivo investigations of hyperthermia for cytostasis of malignant tumors. Combination of chemotherapy and hyperthermia is to potentiate the therapeutic effect. The time interval between the two types of therapy was the main subject of the present investigation. Local hyperthermia (43°C, 60 min) following BCNU chemotherapy at intervals of 0, 3, 6, 9, 12, and 24 h, respectively, was studied in a colonic Yoshida sarcoma model in Sprague-Dawley rats. No significant increase in the curing rate resulted from hyperthermic treatment. The results suggest that the highly anticipated hyperthermic peritoneal lavages should be investigated in controlled animal experiments prior to clinical use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01254653
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  • 111
    Electronic Resource
    Electronic Resource
    Collagen of slow twitch and fast twitch muscle fibres in different types of rat skeletal muscle (1984)
    Springer
    European journal of applied physiology 52 (1984), S. 235-242 
    Details
    ISSN: 1439-6327
    Keywords: Collagen ; Fast and slow twitch fibres ; Skeletal muscle ; Rat ; Endurance training
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The appearance of collagen around individual fast twitch (FT) and slow twitch (ST) muscle fibres was investigated in skeletal muscles with different contractile properties using endurance trained and untrained rats as experimental animals. The collagenous connective tissue was analyzed by measuring hydroxyproline biochemically and by staining collagenous material histochemically in M. soleus (MS), M. rectus femoris (MRF), and M. gastrocnemius (MG). The concentration of hydroxyproline in the ST fibres dissected from MS (2.72±0.35 Μg·mg−1 d.w.) was significantly higher than that of the FT fibres dissected from MRF (1.52±0.33 Μg·mg−1 d.w.). Similarly, the concentration of hydroxyproline was higher in ST (2.54±0.51 ⧎g·mg−1 d.w.) than in FT fibres (1.60±0.43 Μg·mg−1 d.w.), when the fibres were dissected from the same muscle, MG. Histochemical staining of collagenous material agreed with the biochemical evidence that MS and the slow twitch area of MG are more collagenous than MRF and the fast twitch area of MG both at the level of perimysium and endomysium. The variables were not affected by endurance training. When discussing the role of collagen in the function of skeletal muscle it is suggested that the different functional demands of different skeletal muscles are also reflected in the structure of intramuscular connective tissue, even at the level of endomysial collagen. It is supposed that the known differences in the elastic properties of fast tetanic muscle compared to slow tonic muscle as, e.g., the higher compliance of fast muscle could at least partly be explained in terms of the amount, type, and structure of intramuscular collagen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433399
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  • 112
    Electronic Resource
    Electronic Resource
    Immunocytochemical demonstration of caldesmon (a calmodulin-binding, F-actin-interacting protein) in smooth muscle fibers and absorptive epithelial cells in the small intestine of the rat (1984)
    Springer
    Cell & tissue research 235 (1984), S. 207-209 
    Details
    ISSN: 1432-0878
    Keywords: Caldesmon ; Actin ; Immunocytochemistry ; Small intestine ; Smooth muscle ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of caldesmon (a calmodulin-binding, F-actin-interacting protein) (Sobue et al. 1982) and of actin was studied in the rat's small intestine by means of light-microscopic immunocytochemistry. Positive immunostaining for caldesmon was seen in smooth muscle cells of the intestinal wall, and of blood vessels, and in the apical portion of the absorptive epithelial cells. The immunoreactivity in goblet cells was difficult to recognize. The positive reaction to immunostaining for actin showed almost the same pattern as that for caldesmon. These results suggest that this calmodulin-binding protein may play an important role in the control of actin-myosin interaction in smooth muscle cells and in non-muscle cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00213742
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  • 113
    Electronic Resource
    Electronic Resource
    Alteration by estrogen of the nucleoli in nerve cells of the rat hypothalamus (1984)
    Springer
    Cell & tissue research 235 (1984), S. 485-489 
    Details
    ISSN: 1432-0878
    Keywords: Ventromedial nucleus ; Hypothalamus ; Ultra-structure ; Nucleoli ; Estrogen effects ; Chromatin ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Estrogen is accumulated from the blood by nerve cells in the ventromedial nucleus of the hypothalamus and can facilitate female reproductive behavior by acting on this region of the brain. This cell group was examined in ovariectomized female rats, given estrogen or control treatment, by use of light and electron microscopy. A significantly greater portion of the nerve cells in the estrogen-treated animals had protuberances on their nucleolar surfaces, apparent under the light microscope. The fine structure of such protuberances included dense, aggregated material, which is shown to contain DNA by the sodium tungstate staining technique. Because increased numbers of such protuberances were found in nuclei of cells of the experimental group where previous studies demonstrated a significant increase in ultrastructural signs of biosynthetic activity, they may be associated with increased RNA synthesis. Thus, they could indicate, ultrastructurally, increased synthetic rates for RNA in nerve cells through which estrogen promotes reproductive behavior.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226943
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  • 114
    Electronic Resource
    Electronic Resource
    Karyometry of nuclei in liver cells (1984)
    Springer
    Cell & tissue research 235 (1984), S. 669-673 
    Details
    ISSN: 1432-0878
    Keywords: Liver-cell heterogeneity ; Hepatic venous branches ; Karyometry ; Binucleate cells ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In untreated adult male albino rats nuclear volume and the percentage of binucleate cells were determined in the first layer of hepatocytes adjacent to hepatic venous branches of varying diameters (〈40 μm, 40 μm–80 μm, 80 μm–120μm, 120 μm–160 μm, 〉160 μm), and in the third and fourth layer of hepatocytes in the remainder of the perivenous parenchyma. In the first layer of hepatocytes adjacent to the vascular structures means of nuclear volume are significantly lower and percentage of binucleate cells significantly higher than in the cells of the remainder of the perivenous parenchyma. Within each area measured distribution curves of nuclear volume classes were homogeneous but showed heterogeneity in comparison with each other. The morphometric data presented in this study strongly support the opinion of the heterogeneity of liver cells in the perivenous zone, as previously postulated on the basis of histochemical investigations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226967
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  • 115
    Electronic Resource
    Electronic Resource
    A morphometric study of the variations in subcellular structures of rat hepatocytes during 24 hours (1984)
    Springer
    Cell & tissue research 236 (1984), S. 305-315 
    Details
    ISSN: 1432-0878
    Keywords: Hepatocytes ; Rat ; Liver ; Circadian rhythm ; Morphometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Subcellular structures of hepatocytes in periportal and perivenous zones were examined during 24 h. The volume, surface and numerical profile densities of cytoplasmic organelles were analysed morphometrically. Most subcellular structures in periportal and perivenous hepatocytes were subject to strong circadian variations. In hepatocytes from both zones, the volume densities of smooth endoplasmic reticulum (sER), mitochondria, lysosomes, peroxisomes, polysomes and lipid droplets demonstrated peak values at 16.00 h, 20.00 h or 00.00 h; trough values were at 04.00 h, 08.00 h, or 12.00 h, except for peroxisomes (16.00 h). However, the volume densities of glycogen granules and rough endoplasmic reticulum (rER) in periportal and perivenous hepatocytes exhibited maximal values at 04.00 h, 08.00 h or 12.00 h and minimal values at 20.00 h. The surface densities of sER, mitochondria, lysosomes and peroxisomes, and the numerical profile densities of mitochondria, lysosomes and peroxisomes in periportal and perivenous hepatocytes showed similar trends. These events suggest that membranes of the rER show a partial correlation with the sER, mitochondrial and lysosomal membranes during the 24-h span. This may involve the interaction between ribosomes and rER. Almost all cytoplasmic organelles examined displayed significant differences between periportal and perivenous hepatocytes, morphometrically and in fine structure, indicating that the morphofunctional variability of hepatocytes differs depending on the location in the liver acinus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214231
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  • 116
    Electronic Resource
    Electronic Resource
    Mitochondrial binding of triiodothyronine (T3) (1984)
    Springer
    Cell & tissue research 236 (1984), S. 321-325 
    Details
    ISSN: 1432-0878
    Keywords: Triiodothyronine ; Radioautography ; Mitochondria ; Liver ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary To assess the distribution of the thyroid hormone triiodothyronine (T3) within intact living cells, freshly prepared dispersed rat hepatocytes were incubated with [125I]-T3 for periods of 5 min and 30 min. Lightand electron-microscopic (EM) radioautography was carried out to determine the distribution of grains over the isolated cells. Both procedures showed the grains distributed almost entirely over the cytoplasmic matrix rather than the nucleus. Grain counts under the EM were compared with expectation based on established quantitative methods. Only the mitochondria showed obvious and statistically significant grain counts, whereas the nucleus failed to accumulate grains in excess of expectations by chance alone based on area. The findings support the existence of mitochondrial binding of T3, presumably a prerequisite for its action in direct stimulation of the mitochondria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214233
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  • 117
    Electronic Resource
    Electronic Resource
    Intercellular junctions between macrophages in the regional lymph node of the rat after injection of large doses of steroids (1984)
    Springer
    Cell & tissue research 236 (1984), S. 351-355 
    Details
    ISSN: 1432-0878
    Keywords: Lymph node ; Steroids ; Macrophages ; Intercellular junctions ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Intercellular junctions were often found between macrophages in sinuses of regional lymph nodes of the rat after injection of large doses of cholesterol, cortisone acetate, and estrone at the footpad. They were identified by subplasmalemmal densities, 20–50 nm in width, beneath the plasma membranes of apposed macrophages. No distinct filamentous structures were visible in those dense regions. Electron-dense amorphous materials are lined up at the center of the intercellular space in the junctional regions. Some macrophages form clusters with intercellular junctions. No significant difference in the effect of cholesterol, cortisone acetate, and estrone on the number of intercellular junctions betwene macrophages was found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214238
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  • 118
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    Electronic Resource
    Enantiomer separation of some aromatic carboxylic acids by HPLC on a chemically bonded β-cyclodextrin stationary phase (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 147-148 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography ; HPLC ; Racemate separation ; β-Cyclodextrin stationary phase ; Cyclohexylphenylglycolic acid ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070311
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  • 119
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    Electronic Resource
    Multi-mode liquid chromatography of polystyrenes on phenyl-bonded phase (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 158-159 
    Details
    ISSN: 0935-6304
    Keywords: Multi-mode liquid chromatography ; Adsorption chromatography ; Size exclusion chromatography ; Phenyl-bonded phase ; Styrene oligomers ; Polystyrene polymers ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070317
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    Electronic Resource
    Masthead (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984) 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070401
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  • 121
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    Electronic Resource
    HPLC on 3,5-dinitrobenzamidopropyl silica gel (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 160-161 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography HPLC ; Bonded phases ; 3,5-Dinitrobenzamidopropyl silica gel ; Charge transfer interaction ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070318
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  • 122
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    Electronic Resource
    Open tubular column gas chromatography: Theory and practice. Milton L. Lee, Frank J. Yang Keith D. Bartle John Wiley & Sons, New York, 1984, X + 445 pp., US $ 48.00. (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 327-327 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070607
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  • 123
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    Electronic Resource
    Deactivation of fused silica capillary columns with polymethylhydrosiloxanes (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 329-332 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Fused silica capillary columns ; Deactivation ; Polymethylhydrosiloxanes ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070608
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  • 124
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    Electronic Resource
    Multidetection of pesticides in capillary gas chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 338-339 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Pesticides ; Multidetection ; ECD-NPSD-SSD ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070613
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  • 125
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    Electronic Resource
    Clean-up of polynuclear aromatic hydrocarbons and 3-ring azaarenes and their GC-analysis on whisker-walled open tubular columns (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 301-305 
    Details
    ISSN: 0935-6304
    Keywords: Capillary gas chromatography ; Whisker-walled open tubular columns ; PNA-hydrocarbons ; XAD-2 ; Azaarenes ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A modified clean-up of polynuclear aromatic (PNA) hydrocarbons on XAD-2 is described. n-Alkanes (C16—C28) are separated quantitatively from the PNA hydrocarbons and are eluted in one fraction. The distribution of 17 PNA hydrocarbons and four of their alkyl derivatives, two S-heterocyclic compounds and two azaarenes between the different fractions is reported. Azaarenes containing three rings are separated from PNA hydrocarbons and S-heterocyclic compounds. Whisker-walled open tubular columns coated with OV-215 and OV-25 were used in the separation of isomeric azaarenes and in PNA hydrocarbon profile analysis, respectively. The preparation of such columns is described in detail. Rinsing of capillary columns with cold, concentrated HCI after whisker growth removes much larger amounts of boron and sodium than subsequent leaching with HCI at 180°C. Whisker-walled open tubular columns are successfully applied to the characterization of isomeric benzofluoranthenes and other PNA hydrocarbons isolated from air particulate matter.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070603
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  • 126
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    Electronic Resource
    Length of the flooded zone in the column inlet and evaluation of different retention gaps for capillary gas chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 319-326 
    Details
    ISSN: 0935-6304
    Keywords: Capillary GC ; Band broadening in space ; Flooded column inlet ; Retention gap ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In on-column or in splitless injection with recondensation of the solvent, the length of the flooded zone in the column inlet depends primarily on the wettability of the internal wall of the inlet. For columns with a coated inlet this explains why peak distortion due to band broadening in space by a certain sample volume is pronounced in one case and hardly observable in another. Glass or fused silica capillaries silylated with diphenyltetramethyldisilazane were found to give optimal retention gaps. They combine thorough and thermostable deactivation with good wettability and low retention power. On the other hand it is very easy to deactivate fused silica capillaries with Carbowax. The resulting retention gaps are suitable for a wide range of applications and are particularly attractive for the analysis of dirty samples which require frequent replacement of the inlet.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070606
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  • 127
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    Electronic Resource
    On the stability of polarity mixtures used in CGC (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 332-333 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Capillary columns ; Polarity mixtures ; Reaction products ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070609
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  • 128
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    Electronic Resource
    Multidimensional column ion chromatographic determination of tetrafluoroborate and phosphate (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 336-337 
    Details
    ISSN: 0935-6304
    Keywords: Ion chromatography ; Multidimensional column ; Borophosphosilicate glass (BPSG) film ; VLS ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070612
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  • 129
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    Electronic Resource
    Modified equation for the calculation of theoretical plate number and sorbent selection on the basis of retention indices (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 342-343 
    Details
    ISSN: 0935-6304
    Keywords: Gas-liquid chromatography ; Logarithmic retention index ; Equation for the calculation of column efficiency ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070615
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  • 130
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    Electronic Resource
    Masthead (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984) 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070701
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  • 131
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    Electronic Resource
    Chromatography calendar (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 433-435 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070717
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  • 132
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    Electronic Resource
    Direct gas chromatographic analysis of halogenated hydrocarbons at the part-per-trillion level (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 370-374 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Trace analysis ; On-column injection ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Large sample volume on-column injection (up to 250 μL) of n-pentane solutions of halogenated hydrocarbons has been employed for the direct measurement of both low-boiling and high-boiling compounds in what is essentially a single run. Two-bonded phase, fused-silica capillary columns are joined in series, through which the low-boiling compounds are first chromatographed and detected with an electron capture detector. High-boiling compounds are then trapped in a section joining the two columns, and subsequently chromatographed in the second column, using the same detector. This procedure permits analysis at the ppt level.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070706
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  • 133
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    Electronic Resource
    Multidimensional capillary gas chromatography-enantiomeric separations of selected cuts using a chiral second column (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 404-410 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Multidimensional capillary columns ; Enantiomeric separations ; Intermediate trapping ; Mixed polarities ; Terpene alcohols ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070711
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  • 134
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    Determination of nitrated-polyaromatic hydrocarbons (nitro-PAHs) in environmental samples by high resolution chromatographic techniques (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 389-397 
    Details
    ISSN: 0935-6304
    Keywords: Low and high resolution liquid chromatography ; Gas chromatography ; Capillary columns ; Alkali flame detection ; Chemical ionization mass spectrometry ; Nitro-PAHs ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: An analytical procedure is described for the fractionation of organic compounds present in environmental samples and the determination of nitro polyaromatic hydrocarbons (nitro-PAHs). Both low and high resolution liquid chromatography are employed for the prefractionation of the soluble organic fraction (SOF) extracted from particulate matter or gaseous pollutants collected on adsorption traps. High resolution gas chromatography is used to analyze four fractions containing alkanes, PAHs, nitro-PAHs, and other polar PAHs. Nitrogen-containing species are separated by GC and detected specifically using an alkali flame (NPD) detector. Flame ionization (FID) detection, GC-MS of positive ions, and negative ion chemical ionization MS of the whole fraction is used for the identification and quantitation of the various components. The composition of SOF extracted from particulate matter emitted from diesel exhausts is elucidated and a large number of nitro-PAHs identified by the combination of the various techniques.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070709
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  • 135
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    Electronic Resource
    Masthead (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984) 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070901
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  • 136
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    Characterization of OV-1/FFAP-mixture coated glass capillary columns used for the separation of free fatty acids (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 509-514 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; OV-1/FFAP mixed phase, high-temperature ; silylated glass capillary ; Polar phase-coated HTS capillary ; Golay curves of mixed phases ; Thermal and long-term stability of OV-1/FFAP ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: As an alternative to acid pretreated UCON and FFAP capillaries for the analysis of wide-boiling free fatty acid mixtures, OV-1 : FFAP phase mixtures were used on high-temperature silylated inert glass capillary columns. The HETP-carrier gas velocity curves, peak asymmetry factors, coating efficiency, gas phase and stationary phase contributions to the mass transfer resistance were determined for various OV-1 : FFAP ratios. Mixed-phase capillaries showed optimum performance at a 2 : 1 OV-1 : FFAP ratio. The thermal and long-term stability of OV-1-stabilized FFAP columns surpassed those of the UCON and pure FFAP reference column used.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070903
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  • 137
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    Electronic Resource
    The length of the zone flooded by the injection of large volumes onto retention gaps in capillary GC (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 531-532 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Capillary columns ; Retention gaps ; Large sample volumes ; Flooded zone ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070908
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  • 138
    Electronic Resource
    Electronic Resource
    High speed zone electrophoresis in open-tubular fused silica capillaries (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 529-531 
    Details
    ISSN: 0935-6304
    Keywords: Capillary electrophoresis ; High resolution separation ; High speed analysis ; Dansyl amino acids ; Fluorescamine labeled peptides ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070907
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  • 139
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    Electronic Resource
    Advantages and limits of the quantitative determination of α-ferrocenyl carbinols with capillary GC (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 536-537 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Capillary column ; On-Column injection ; Vaporizing injection ; Decomposition ; α-Ferrocenyl carbinols ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070910
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  • 140
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    Electronic Resource
    Non-suppressed ion chromatography of carbonate and nitrite on steel surfaces (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 580-581 
    Details
    ISSN: 0935-6304
    Keywords: Ion chromatography, IC ; Steel surface analysis ; Carbonate, chloride, nitrite ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071008
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  • 141
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    Electronic Resource
    Immobilization of stationary phase films by gamma radiation. Part 1. Nonpolar phases, regular and thick-film capillaries (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 620-624 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Glass capillary columns ; Immobilization ; Gamma radiation ; Very thick films ; Nonpolar stationary phases ; OV-1, OV-101, SE-54 ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Borosilicate glass capillaries, silylated and coated with OV-1 or SE-54, were irradiated by a 60Co gamma source. The effect of radiation on chromatographic performance was determined for a series of dosages and was evaluated before and after rinsing with solvent. Results for both regular and thick films were obtained.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071104
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  • 142
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    Trace Enrichment of marine algal pigments for use with HPLC-diode array spectroscopy (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 632-635 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Diode array spectroscopy ; Trace enrichment ; Algal pigments ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071107
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  • 143
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    Rapid determination of major congeners in distilled spirits by direct analysis on bonded capillary columns (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 641-643 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Fused silica capillary columns ; Bonded stationary phase ; Distilled beverages ; Direct analysis ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071111
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  • 144
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    Chromatography calendar (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 649-652 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071115
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  • 145
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    Separation of isomers of nitro-polycyclic aromatic hydrocarbons (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 671-678 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Isomer separation ; Mutagenic compounds ; Nitropolycyclic aromatic hydrocarbons ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Since positional isomers of several nitro-polycyclic aromatic hydrocarbons (nitro-PAH) contain widely different mutagenic properties, methods for separating the isomers were investigated. High performance liquid chromatography with dichloromethane in hexane on silica gave the best resolution for the majority of the compounds. A few groups of isomers were better resolved with other modifiers or with reversed phases. Of the reversed phase systems, methanol-water gave better resolution than acetonitrile-water. With dichloromethane/hexane on silica, the retention was found to depend on the presence of a bay nitro group (first), the number of H atoms peri to the nitro group (second), and the length/breadth ratio of the molecule (third).Front electron density calculations were combined with the structure-retention relations in making tentative structure assignments of minor isomers of nitro-PAH.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071203
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  • 146
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    Immobilization of stationary phase films by gamma radiation. Part 2 medium-polarity OV-1701-Vi phase (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 700-701 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Glass capillary columns ; Immobilization ; 60Co gamma radiation ; Medium-polarity phase ; OV-1701-Vi ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071207
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  • 147
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    Changes in peak width and concentration at the inlet and outlet of a chromatographic column (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 615-619 
    Details
    ISSN: 0935-6304
    Keywords: Theory ; Sorption ; Plate model ; Band widths ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The original plate model of chromatography is extended to the sorption process occurring at the column inlet and the desorption process at the column exit. At the column inlet it is shown that sufficiently wide feed bands undergo no change in concentration but a fall in band width, i.e., the volume of mobile phase occupied by the solute band is reduced. The reduction factor is (1 + k) where k is the mass distribution ratio (capacity factor). Narrower bands suffer partial reduction in both band width and concentration. On desorption at the outlet, however, the change is always in band width and not concentration. A perfect detector registers the true concentration-time profile of the band in the column if the solute mass fraction in the stationary phase is below 10-3 at the column outlet. The risks of stripping the stationary phase at high solute concentrations in analytical and preparative or production gas chromatography are compared.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071103
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    Resolution of gossypol: Analytical and preparative HPLC (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 629-631 
    Details
    ISSN: 0935-6304
    Keywords: Preparative liquid chromatography, HPLC ; Chiral HPLC columns ; (-)-Gossypol ; Resolution of enatiomers ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071106
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  • 149
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    Effluent stream splitting to two different detectors (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 639-640 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Flame ionization detector, FID ; Electron capture detector, ECD ; Effluent splitting ; Pesticides ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071110
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  • 150
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    Errata (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 647-647 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071114
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  • 151
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    HPTLC separation of PGF2α, PGE1, PGE2, PGA1 prostaglandins and quantitative determination in situ by induced fluorescence (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 593-595 
    Details
    ISSN: 0935-6304
    Keywords: High performance thin layer chromatography, HPTLC ; Fluorescence ; Prostaglandins ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071013
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  • 152
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    Product news (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 601-604 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071017
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  • 153
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    Reaction gas chromatography/mass spectrometry. Part IXFor Part VIII, see [1].: Post-column hydrodesulfurization in capillary GC/MS as an aid in structure elucidation of cyclic sulfides within mixtures (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 625-628 
    Details
    ISSN: 0935-6304
    Keywords: Reaction gas chromatography/mass spectrometry, GC/MS ; Capillary columns ; Post-column hydrodesulfurization ; Cyclic sulfides ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: This article describes a method that assists in structure determination of cyclic sulfides mixtures by GC/MS. The method involves the use of a gas-phase hydrodesulfurization microreactor (AP-56 catalyst, reaction temperture 300-315°C, hydrogen as a carrier and reagent gas) located between the capillary column (OV-17) and the mass spectrometer. The presence of a microreactor in such a position does not essentially affect the chromatographic separation achieved by using the capillary column. Combined analysis of the mass spectra registered for the original sulfides and the hydrodesulfurization products permits the structure determination of each effluent to be made more reliably. This is illustrated by the investigation of a reaction mixture containing the structural and geometric isomers of methyl-substituted thiabicyclononanes.
    Additional Material: 6 Ill.
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    URL: http://dx.doi.org/10.1002/jhrc.1240071105
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  • 154
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    Separation of 3- to 6-ring polycyclic aromatic hydrocarbons by capillary gas chromatography with a liquid crystal as stationary phase (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 637-638 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Glass capillary columns ; Liquid crystal ; Polycyclic aromatic hydrocarbons (PAH) ; N,N′-Bis(p-butoxybenzylidene)-α,α′-bi-p-toluidine (BBBT) ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071109
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  • 155
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    Masthead (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984) 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071201
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  • 156
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    Rapid and reproducible injection onto microbore columns (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 703-706 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Fused silica microbore columns ; Automated injection ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071209
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  • 157
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    Solute focusing using the solvent effect  -  A mass spectrometric investigation of packed bed inlets (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 142-143 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Solute focussing ; Solvent effect ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070309
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  • 158
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    Determination of silanol groups on surface of sorbents for HPLC (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 153-154 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Silanized silica for HPLC ; Surface silanol groups ; Dimethylzinc tetrahydrofuranate ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070314
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  • 159
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    High performance liquid chromatography profiling of prostaglandins (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 156-157 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; HPLC profiling ; Prostaglandins ; High speed HPLC ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070316
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  • 160
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    Application of a multichannel photodiode array UV-visible detector to the analysis of components of a medicine by micro high-performance liquid chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 151-152 
    Details
    ISSN: 0935-6304
    Keywords: Micro HPLC ; Multichannel photodiode array detector ; Components in a medicine ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070313
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  • 161
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    High performance thin layer chromatography - densitometric method for content uniformity test of lanatoside C tablets (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 161-164 
    Details
    ISSN: 0935-6304
    Keywords: High-performance-thin layer chromatography, HPTLC ; Zirconium oxychloride ; Backside fluorodensitometric detection on TLC plate ; Content uniformity test for lanatoside C tablets ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070319
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  • 162
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    Developments in pyrolysis capillary GC (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 172-184 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070402
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  • 163
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    The use of coupled columns for the capillary gas chromatographic separation of water pollutants (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 215-217 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Capillary, fused silica ; Coupled columns ; Halogenated organic pollutants ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070410
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  • 164
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    Tswett medals 1984 (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 225-226 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070414
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  • 165
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    Separation of distearoylphosphatidylcholine, dipalmitoylphosphatidylcholine, and dioleylphosphatidylcholine by thin-layer chromatography using new modified plates (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 211-212 
    Details
    ISSN: 0935-6304
    Keywords: Thin layer chromatography, TLC ; Alkylchlorosilanes ; Phosphatidylcholines ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070408
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  • 166
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    High-speed micro-HPLC for analysis of polycaclic aromatic hydrocarbons in environmental samples (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 218-219 
    Details
    ISSN: 0935-6304
    Keywords: High-speed micro-HPLC ; Rapid Identification ; Polycyclic aromatic hydrocarbons ; Environmental sample ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070411
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  • 167
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    Chromatographic mechanisms of coated porous polymers: Chromosorb 102 coated with squalane (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 222-224 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Interface ; Partition ; Adsorption ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070413
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  • 168
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    Contemporary capillary columns for gas chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 232-244 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070502
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  • 169
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    The role of column technology in capillary gas chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 252-257 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: After having witnessed, over a period of more than 20 years, the extremely difficult early development of capillary gas chromatography, the growth of scientific understandign, and finally its sudden blossoming into a commonly accepted technique, the author is confronted with a dichotomy. On the one hand, there are the dramatic advances in the fields of column preparation, and of sampling techniques. Implementation of these advances should logically result in correspondingly drastic progress in the average quality of application work in drastic progress in the average quality of application work in capillary gas chromatography. On the other hand, however, such progress is lacking. The greater the practical potential, the smaller the fractionm of that potential which is practically exploited. The reason is that most users interpret te recent advances as exempting them from their obligation to know and think about the many details of practical work, and to attempt standardized work with standard columns and techniques. Standardization of routine work is beneficial, provided the standards are optimized-a condition which all too often remains unfulfilled. Research work, performed in a realm of ever new and unknown conditions, is of poor quality when done by standardized means. Since the most critical part of optimization is column selection, the capillary column must be mastered as a familiar tool in the hands of the investigator. This is hardly possible in the absence of any direct contact with column technology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070504
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  • 170
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    Determination of flurazepam and its hydroxyethyl and dealkyl metabolites by some packed and capillary ECD-GLC methods: Application to pharmacokinetic studies (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 258-264 
    Details
    ISSN: 0935-6304
    Keywords: Gas-liquid chromatography ; Packed and capillary columns ; Plasma anaysis ; Pharmacokinetic studies ; Benzodiazepines ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A sensitive gas-liquid chromatographic assay was developed for plasma determinations of flurazepam (F), N1-desalkylflurazepam (DF), and N1-hydroxyethylflurazepam (HF). The internal standards used were delorazepam for F and DF and 1 ã-hydroxymidazolam for HF. Following extraction and derivatization for HF, these compounds were analyzed by ECD-GLC, using either glass packed columns (poly A 103 for F and DF, OV 225 for HF) or CP-Sil 5 capillary columns for DF and HF. The detection limit of the packed-column assay was approximately 3ng/ml for HF and DF, and 5ng/ml for F; with capillary GLC analysis, the sensitivity limit for HF and DF was lower than 1 ng/ml. These methods were used for pharmacokinetic investigations after i. v. administration of these compunds.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070505
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  • 171
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    HPLC in packed microbore flexible silica capillaries. Part 2: Estimation and calculation of extra-column band broadening (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 276-278 
    Details
    ISSN: 0935-6304
    Keywords: HPLC, Packed microbore columns ; Band broadening and flow rate ; Calculated van Deemter plot ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070510
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  • 172
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    Activated carbon fiber as stationary phase in gas chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 282-283 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Gas analysis ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070513
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  • 173
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    Product news (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 286-288 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070515
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  • 174
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    Citation of books on chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 296-300 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 9 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070602
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  • 175
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    Large sample injection method (≥ 100 μL) for capillary GC using a commercial thermodesorption unit as injection device (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 306-311 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Capillary columns ; Thermodesorption ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A commercial thermodesorption and cold trap unit can be used as a large sample volume injection device in high resolution gas chromatography. Volumes of more than 100 μl can be injected. More than 97% of solvents, such as hexane, can be removed by a Tenax TA precolumn without any loss of compounds with volatilities comparable to naphthalene. Experimental conditions, recovery rates of polycyclic aromatic hydrocarbons, and the reproducibility of the method are described in detail. The method was successfully applied for the determination of PAH in air particulate matter extracts.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070604
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  • 176
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    Supplementary comment on the paper “On the stability of polarity mixtures used in CGC” (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 333-333 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070610
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  • 177
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    Stability of dibenzothiophene oxides under gas chromatographic conditions (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 334-335 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Fused-Silica columns ; Thermal stability ; Dibenzothiophene oxides ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070611
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  • 178
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    A miniature gradient elution system for liquid chromatography with packed capillary columns (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 411-413 
    Details
    ISSN: 0935-6304
    Keywords: Packed capillary columns ; Miniaturized gradient elution ; Polynuclear aromatic hydrocarbons ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A miniaturized continuous gradient elution system was designed for work with packed capillary columns. The retention reproducibility achieved is adequate for many practical applications.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070712
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  • 179
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    Peak broadening in isothermal runs due to large retention gaps in capillary GC? (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 461-465 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Capillary columns ; Retention gaps ; Peak broadening ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A simple formula is derived which allows estimation of the band broadening due to longitudinal diffusion in retention gaps for isothermal runs with the column held at the injection temperature. The broadening is strongly dependent on the linear gas velocity in the retention gap. If the internal diameters of the retention gap and the separation column are similar, the retention gap may have a length exceeding 100 m, even if the separation column is only 10 m long. A 0.5 mm I.D. retention gap attached to a 0.3 mm I.D. separation column (of interest for automatic on-column injection) may be several meters long. Retention gaps of 0.3 mm I.D. may be used for on-column injections into separation columns with I.D's. down to about 0.1 mm.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070803
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  • 180
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    Electronic Resource
    Device for injection of absorbent-trapped compounds on to a WCOT column (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 477-479 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Glass capillary column ; Adsorbent ; Cold trapping ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070806
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  • 181
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    Increased speed of steroid analysis by capillary GC and GC-MS; effects of sample pretreatment and sample introdution (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 414-422 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Capillary columns ; Steroid analysis ; Sample pretreatment ; Sample introduction ; Separation speed ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Quantitative analysis of steroids and their metabolites in urine samples calls for increased speed of sample clean-up, of the derivatization procedure, and of separation. A fast procedure for sample pretreatment, which can be performed within 8 hours, is introduced and evaluated. It is shown that use of fast pretreatment in combination with narrow bore columns, which are compatible with existing instrumentation, can considerably increase, laboratory throughput. The effect of different sample introduction techniques (e.g. splitless, on-column, and moving needle) on column efficiency and resolution is demonstrated and discussed.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070713
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  • 182
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    Electronic Resource
    Liquid chromatography in environmental analysis. James F. Lawrence, editor. Humana Press, XVI + 374 pp., U.S. $55.00 (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 435-435 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070718
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  • 183
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    HPLC of nucleotides. II. General methods and their development for analysis and preparative separation. An approach to selectivity controlThis review was presented at the Budapest Chromatography Conference, June 1983, as a report and two posters. Part of it was included in [1]. Abbreviations: r - denotes ribonucleotides; d - (deoxy) is omitted; p - denotes terminal phosphate groups; internucleotide phosphate groups also are omitted. (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 442-460 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; General methods of nucleotide HPLC ; Molecular and ionic basis of separation ; Two-dimensional separation ; Stationary phase; selectivity to nucleotide size and composition, selectivity control ; Mobile phase (solvent, salt, pH), influence on retention and selectivity ; Guard-column functions ; Column loadability and packing, consolidation of bed particles ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In order to develop efficient separation methods for nucleotides according to their size and heterocyclic composition, the application of ion-exchange, reverse-phase, and normal-phase adsorption HPLC has been studied. The comparative investigation of retention power and selectivity of various packings (non-polar bonded-phase and amino silicas) in relation to nucleotide length and composition yields data which enable suitable packings to be selected and a method of preparing the new packing for a particular separation problem to be formulated. Thus a new anion exchanger with high selectivity and dynamic mass transfer has been prepared for fractionation of large oligonucleotides. The effect of the eluent pH and composition (organic modifier, salt) on retention, selectivity, and resolution in ion-exchange and reverse-phase HPLC has been studied. The optimum separation conditions comprise elution with oppositely directed gradients of the salt and the modifier, use of a precolumn packing that provides the best protection for the main column without loss of its efficiency, and the optimum gradient program for the desired retention of the component of interest. The relation between loading and sample concentration has been studied and the system for gradient elution improved. Our work shows that two-dimensional separation is the most reliable and informative method for preparation of homogeneous oligonucleotides. The hydrophobic-pair ion-exchange mechanism is proposed for ion-pair chromatography. Protected and partially deblocked oligonucleotides, chemically synthesized for genetic engineering studies, have been separated with high selectivity by adsorption (normal-phase) HPLC which is efficient for gradient elution with isohydric eluents. The analysis of a monomeric composition of nano-(pico-) molar amounts of oligonucleotides has been developed; the procedure involves microcolumn digestion of the oligonucleotides with immobilized enzymes followed by microcolumn separation of the nucleoside-mononucleotide mixture. Also, a new slurry method for packing stable HPLC columns with a tightly consolidated, nonshrinkable bed of particles has been developed.
    Additional Material: 31 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070802
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  • 184
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    Electronic Resource
    Filter extraction in closed loop stripping analysis (CLSA) (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 492-494 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Capillary, glass ; Closed loop stripping analysis ; Filter extraction ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070811
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  • 185
    Electronic Resource
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    Gas chromatographic determination of residual ethylene oxide in gas-sterilized, medical-grade plastics (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 587-589 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Packed glass columns ; Solvent extraction ; Plastics ; Ethylene oxide ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071011
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  • 186
    Electronic Resource
    Electronic Resource
    Comment on the paper “large sample injection method (≥ 100 μL) for capillary GC using a commercial thermodesorption unit as injection device” (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 597-598 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071015
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  • 187
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    Electronic Resource
    Separation of arachidonic acid metabolites by thin-layer chromatography using new silicone-bonded plates (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 538-539 
    Details
    ISSN: 0935-6304
    Keywords: Thin-layer chromatography, TLC ; Alkylchlorosilanes ; Prostaglandins ; Hydroxyelcosatetraenoic acids ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070911
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  • 188
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    Product news (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 549-552 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070915
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  • 189
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    Determination of tetraiodothyronine in serum by HPLC and electrochemical detection (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 566-569 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Electrochemical detection ; Serum ; Tetraiodothyronine ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Tetraiodo-L-thyronine (T4) in human serum was determined by HPLC using a nonphysiological internal standard. For sample preparation, a cation exchange resin, RP-chromatography on C-18 or phenylphase, and electrochemical detection (Metrohm 656 or BAS-LC 4 A) were employed. The mobile phase (0.8 ml/min) was 10 mM H3PO4/CH3OH (40/60 v/v) or 10 mM H3PO4/CH3CN (70/30 v/v, 1.5 ml/min), the voltage applied 800 mV. The coefficient of variation (day to day) was 6.8% (N = 40); concentrations of T4 found were 11 to 20% lower than those obtained by two different commercially available immunoassays.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071004
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  • 190
    Electronic Resource
    Electronic Resource
    Flexible capillary effluent splitter of the “all-glass” type (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 578-579 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Capillary columns ; Effluent splitter, all glass type ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071007
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  • 191
    Electronic Resource
    Electronic Resource
    Pressure and temperature dependent chromatographic behavior of n-pentane (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 590-592 
    Details
    ISSN: 0935-6304
    Keywords: Pressurized gas ; Supercritical fluid ; Elution and resolution behavior ; n-Pentane ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071012
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  • 192
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    Andrey Vladimirovich Kiselev (1908-1984) (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 599-599 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071016
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  • 193
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    Electronic Resource
    Pesticide residue analysis by open tubular column gas chromatography: Trials, tribulations, and trends (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 660-670 
    Details
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071202
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  • 194
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    Electronic Resource
    On-column injection technique for use with 100 μm I.D. capillary columns (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 697-699 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Capillary columns, 100 μm I.D. ; On-column injector ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071206
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  • 195
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    Electronic Resource
    Supercritical fluid chromatography/diffuse reflectance Fourier transform infrared spectrometry (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 707-709 
    Details
    ISSN: 0935-6304
    Keywords: Supercritical fluid chromatography, SFC ; Diffuse reflectance infrared spectrometry ; Fourier transform infrared spectrometry ; Spectrometry/chromatography interface ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071210
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  • 196
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    Electronic Resource
    Valveless flow switching using constant flow controllers (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 577-577 
    Details
    ISSN: 0935-6304
    Keywords: Multidimensional gas chromatography, MGC ; Deans System ; Temperature programming ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071006
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  • 197
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    Electronic Resource
    HPLC analysis of steroid esters (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 584-586 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Normal and reversed phases ; Steroid esters ; Long-acting contraceptive ; Injectable contraceptives ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071010
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  • 198
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    Electronic Resource
    HPLC on n-propyl picryl ether silica gel (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 714-715 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Bonded phases ; Charge-transfer interaction ; n-Propyl picryl ether ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071213
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  • 199
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    High performance liquid chromatographic determination of phenylenediamines in process wastewaters using electrochemical detection (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 709-711 
    Details
    ISSN: 0935-6304
    Keywords: Liquid chromatography, HPLC ; Electrochemical detection ; Phenylenediamines ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240071211
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  • 200
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    Electronic Resource
    Improved capillary GC/MS interface (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 137-139 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Deactivated fused silica tubing ; Zero dead volume union ; Capillary column GC/MS interface ; Test mixture for non-polar columns ; Test mixture of phenols ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240070307
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