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  • 1995-1999  (196)
  • 1995  (196)
  • Magnetic resonance imaging  (196)
  • Nuclear reactions
  • 101
    ISSN: 1432-1920
    Keywords: Key words Astrocytoma ; Neural network ; Magnetic resonance imaging ; Brain neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Several MRI features of supratentorial astrocytomas are associated with high histologic grade by statistically significant p values. We sought to apply this information prospectively to a group of astrocytomas in the prediction of tumor grade. We used 10 MRI features of fibrillary astrocytomas from 52 patient studies to develop neural network and multiple linear regression models for practical use in predicting tumor grade. The models were tested prospectively on MR images from 29 patient studies. The performance of the models was compared against that of a radiologist. Neural network accuracy was 61 % in distinguishing between low and high grade tumors. Multiple linear regression achieved an accuracy of 59 %. Assessment of the images by a radiologist yielded 57 % accuracy. We conclude that while certain MRI parameters may be statistically related to astrocytoma histologic grade, neural network and linear regression models cannot reliably use them to predict tumor grade.
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  • 102
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 287-288 
    ISSN: 1432-1920
    Keywords: Key words Amyotrophic lateral sclerosis ; Magnetic resonance imaging ; Corpus callosum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abnormal high signal in the corticospinal tracts on MRI has been described in amyotrophic lateral sclerosis. We report a case with further high signal in fibres of the corpus callosum on proton density and T2-weighted spin-echo images, closely matching findings of earlier pathological reports.
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  • 103
    ISSN: 1432-1920
    Keywords: Trigeminal neuralgia ; Magnetic resonance imaging ; MR tomographic angiography ; Vascular compression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A combination of MRI, MR angiography and MR tomographic angiography (MRTA) was used to study the relationship to the root exit zone of the trigeminal nerve to surrounding vascular structures in seven patients with trigeminal neuralgia (TN) and ten patients with no evidence at a lesion in this region. MRTA is the technique for showing the relationship between vessels, cranial nerves and brain stem. MRTA clearly demonstrated the presence of a vessel at the root exit zone of the trigeminal nerve in all patients with TN. In the ten other patients, examination of 20 trigeminal nerves revealed that only one nerve (5%) was in contact with a vessel at the root exit zone. This study supports vascular compression of trigeminal nerves as a cause of TN, and demonstrates the value of MRTA as noninvasive technique for demonstrating compression.
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  • 104
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 356-361 
    ISSN: 1432-1920
    Keywords: Moyamoya disease ; Magnetic resonance imaging ; Cerebral angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our purpose was to evaluate the diagnostic accuracy of MRI in moyamoya disease. We studied 30 patients with this disease, comparing MRI and angiographic findings. The diagnostic value of MRI was evaluated for occlusive lesions, collateral vessels, and parenchymal lesions. In all patients bilateral occlusion or stenosis of the supraclinoid internal carotid artery and proximal anterior and middle cerebral arteries was clearly shown by MRI, and staging of the extent of occlusion agreed with angiographic staging in 44 (73%) of 60 arteries. MRI, particularly coronal images, clearly showed basal cerebral moyamoya vessels in 54 hemispheres, and 45 of a total of 71 large leptomeningeal and transdural collateral vessels were identified. MRI also showed parenchymal lesions in 48 (80%) hemispheres, and the extent of occlusion in the anterior and posterior circulations respectively correlated with white matter and cortical and/or subcortical infarcts.
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  • 105
    ISSN: 1432-1920
    Keywords: Corpus callosum ; Hydrocephalus ; Dementia ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate morphological changes in the corpus callosum in hydrocephalus and to correlate them with clinical findings we studied sagittal T2*-weighted cine MR images of 163 patients with hydrocephalus. The height, length and cross-sectional area of the corpus callosum were measured and related to the type of cerebrospinal fluid flow anomaly and to clinical features, especially dementia. With expansion of the lateral ventricles the corpus callosum showed mainly elevation of its body and, to a lesser degree, increase in length. Upward bowing was more pronounced in noncommunicating than in communicating hydrocephalus. Dorsal impingement on the corpus callosum by the free edge of the falx correlated with the height of the corpus callosum. Cross-sectional area did not correlate with either height, length or impingement; it was, however, the strongest anatomical discriminator between demented and nondemented patients. The area of the corpus callosum was significantly smaller in patients with white matter disease. Our findings suggest that, due to its plasticity, the corpus callosum can to some degree resist distortion in hydrocephalus. Dementia, although statistically related to atrophy of the corpus callosum, is possibly more directly related to white matter disease.
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  • 106
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 649-652 
    ISSN: 1432-1920
    Keywords: Carmofur ; 5-Fluorouracil ; Leukoencephalopathy ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Carmofur, a derivative of 5-fluorouracil, has recently been noted to have an infrequent but serious association with leukoencephalopathy. To our knowledge, there has been no report of early MRI findings in this leukoencephalopathy. We describe a case in which diffuse high signal intensity of the entire cerebral white matter, including the corpus callosum, was seen on T2-weighted magnetic resonance images. Although similar findings can be seen in many other diseases, carmofur-induced leukoencephalopathy should be suspected in a patient treated with carmofur. It is important to know the clinical and MRI characteristics of this condition, for early diagnosis and better prognosis.
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  • 107
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 331-333 
    ISSN: 1432-1920
    Keywords: Key words Mineralizing microangiopathy ; Chemotherapy ; Radiotherapy ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mineralizing microangiopathy, a distinctive histopathologic process involving the microvasculature of the central nervous system (CNS), is usually seen following combined radiation and chemotherapy for the treatment of CNS neoplasms in childhood. CT typically demonstrates calcification within the basal ganglia and subcortical white matter. The areas of calcification may give paradoxically increased signal on T1-weighted MRI due to a surface-relaxation mechanism, and decreased signal on T2-weighted images.
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  • 108
    ISSN: 1432-1920
    Keywords: Hyperhomocysteinaemia ; Premature arteriosclerosis ; Demyelination ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Severe or even mild hyperhomocysteinaemia can cause a wide range of neurological problems. In recent years its vascular complications, including cerebral stroke, in children and young adults have gained special interest, because hyperhomocysteinaemia is treatable and recurrence of vascular incidents may be preventable. Current knowledge about biochemical mechanisms leading to hyperhomocysteinaemia, the pathogenesis of vascular pathology and neurological disfunction, and the various patterns of cerebral damage are reviewed. The significance of MRI in diagnosis, follow-up and research on hyperhomocysteinaemia is discussed.
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  • 109
    ISSN: 1432-1920
    Keywords: Key words Children ; Chloral hydrate ; Magnetic resonance imaging ; Sedation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Orally administered chloral hydrate is the most widely used sedative in children undergoing MRI. We compared intermediate- and high-dose oral chloral hydrate in 97 consecutive children undergoing MRI in a prospective, controlled, double-blind, randomised clinical trial. There were 50 girls and 47 boys, mean weight (± SD) 14.7 ± 6.4 kg, and mean age 38 ± 31. The children were randomly allocated to receive chloral hydrate syrup either 70 mg/kg (group A, n = 50) or 100 mg/kg (group B, n = 47). These two groups were not significantly different in sex, weight, age, diagnosis or ambulatory medication. The mean initial dose (± SEM) was 64 ± 2 mg/kg for group A and 93 ± 2 mg/kg for group B. Because adequate sedation was not achieved, 14 patients in group A and 6 in group B required a second dose, giving a mean total dose of 70 ± 2 mg/kg for group A and 96 ± 2 mg/kg for group B. The percentage of successful examinations after the initial dose (A: 64 %, B: 87 %; p 〈 0.05) and the total dose (A: 92 %, B: 100 %; p = 0.14) was higher in group B. Significant differences were found for the time of onset of sedation (A: 28 ± 2 min, B: 21 ± 1 min; p 〈 0.05), but not for the time to spontaneous awakening after the completion of the examination. The rate of adverse reactions was similar (A: 20 %, B: 21 %; p = 1.00). We conclude that high-dose oral chloral hydrate improves the management of children undergoing MRI.
    Type of Medium: Electronic Resource
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  • 110
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 462-464 
    ISSN: 1432-1920
    Keywords: Epidural abscess ; Magnetic resonance imaging ; Gadolinium-DTPA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 10-year-old boy presented with a 7-day history of back pain and pyrexia. MRI showed an epidural abscess arising from septic arthritis in a lumbar facet joint. Whilst septic arthritis in a large joint is relatively common in children, epidural abscess is rare. This case illustrates how infection in a synovial joint may extend into the extradural space and might be the route of infection in more cases than has previously been recognised.
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  • 111
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 479-480 
    ISSN: 1432-1920
    Keywords: Meningioma ; Internal auditory meatus ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe an entirely intracanalicular meningioma in a 49-year-old woman, mimicking an acoustic neuroma on CT cisternography and MRI.
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  • 112
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 481-485 
    ISSN: 1432-1920
    Keywords: Brain neoplasms ; Gliofibroma ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe CT and MRI appearances in two children with pathologically proven gliofibromas, in the cerebrum and cerebellum. A striking finding was lack of high signal on T2-weighted MRI.
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  • 113
    ISSN: 1432-1920
    Keywords: Hereditary motor and sensory neuropathy type III ; Sural nerve ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated two patients with herediatary motor and sensory neuropathy type III, one with Déjérine-Sottas disease and the other with congenital hypomyelination neuropathy based on nerve pathology and MRI of the sciatic nerve. On biopsy of the sural nerve of the patient with Déjérine-Sottas disease, myelin debris, indicating demyelination, was observed in an onion-bulb pattern surrounding myelinated fibres. In the patient with congenital hypomyelination neuropathy, onion bulbs were formed of two parallel layers of basement membrane. There was no evidence of myelin breakdown. On axial T2-weighted MRI, a severely hypertropied sciatic nerve containing multiple rounded lesions, suggesting inflammation or demyelination, was observed in the patient with Déjérine-Sottas disease. In contrast, the sciatic nerve of the patient with congenital hypomyelination neuropathy showed slight hypertrophy without demyelination. MRI of the sciatic nerve may represent a useful tool for characterisation of demyelinating disease and its prognosis.
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  • 114
    ISSN: 1432-1920
    Keywords: Key words Spinal cord ; Infarction ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract WE report the MRI findings in two patients with presumed cervical spinal cord infarcts in the anterior spinal artery territory. MRI revealed abnormal signal intensities and/or band-like enhancement in the anterior two-thirds of the cervical spinal cord, corresponding to the vascular territory of the anterior spinal artery. Clinically there was an anterior spinal cord syndrome.
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  • 115
    ISSN: 1432-1920
    Keywords: Key words Encephalitis ; Magnetic resonance imaging ; Follow-up examinations ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined 14 children aged 28 days to 12.7 years with encephalitis by CT or MRI. Of the patients examined by CT 58 % had a normal first scan, whereas all MRI investigations demonstrated abnormalities. The clinical features correlated with several MRI investigations. On MRI herpes (HSV) encephalitis started in the medial temporal lobe and encephalomalacia developed within a few weeks. All patients had a follow-up examination 0.5 to 6.5 years after the acute phase. MRI revealed abnormalities in 13 of the 14 children; one boy, with lesions in only the white matter, had a normal follow-up MRI. Even with immediate, optimal therapy the children demonstrated severe parenchymal abnormalities. Signal abnormalities seen in the acute phase of the disease were likely to persist. In children with HSV encephalitis atypical lesions in different areas were seen.
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  • 116
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 38 (1995), S. 84-86 
    ISSN: 1432-1920
    Keywords: Key words Oculodental digital dysplasia ; Magnetic resonance imaging ; Genetic disorder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Oculodental digital dysplasia (ODDD) is an uncommon inherited disorder with characteristic facial abnormalities, defects in dentition and syndactyly; previous reports have described neurologic dysfunction. We present neuroimaging features of a mother and daughter with ODDD; despite only the mother having neurologic dysfunction, the MRI findings in both are strikingly similar.
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  • 117
    ISSN: 1432-1920
    Keywords: Astrocytoma ; Neural network ; Magnetic resonance imaging ; Brain neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Several MRI features of supratentorial astrocytomas are associated with high histologic grade by statistically significant p values. We sought to apply this information prospectively to a group of astrocytomas in the prediction of tumor grade. We used 10 MRI features of fibrillary astrocytomas from 52 patient studies to develop neural network and multiple linear regression models for practical use in predicting tumor grade. The models were tested prospectively on MR images from 29 patient studies. The performance of the models was compared against that of a radiologist. Neural network accuracy was 61% in distinguishing between low and high grade tumors. Multiple linear regression achieved an accuracy of 59%. Assessment of the images by a radiologist yielded 57% accuracy. We conclude that while certain MRI parameters may be statistically related to astrocytoma histologic grade, neural network and linear regression models cannot reliably use them to predict tumor grade.
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  • 118
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging ; Surface anatomy scanning ; Brain tumours ; Cortical veins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We evaluated the usefulness of surface anatomy scanning (SAS) in intracranial tumours, comparing it with surgical findings. We examined 31 patients with brain tumours preoperatively. The tumours included 16 meningiomas, 8 gliomas, 4 metastases and 3 others. SAS clearly demonstrated the tumours, allowing them to be distinguished from the structures of the brain surface, including oedema, except in cases of metastasis. SAS clearly demonstrated large cortical veins. SAS is useful for three-dimensional delineation of the brain surface before surgery.
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  • 119
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 297-302 
    ISSN: 1432-1920
    Keywords: Angiographically occult malformation ; Spinal arteriovenous malformation ; Cavernous malformation ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We reviewed 11 cases of intramedullary cavernous haemangiomas (IMCH) studied by MRI, to assess its diagnostic value in these lesions. Follow-up MRI was obtained in five patients 7 days-2 years following the initial study. In one case a postoperative examination was obtained. The diagnosis was pathologically proven in ten cases, and supported in the last by a family and personal history of cavernous haemangiomas. A reticulate appearance with areas of mixed signal intensity in both T1-and T2-weighted images was the most common finding. Homogeneous high, low or intermediate signal intensity was each found in one case, Two small lesions gave low signal. A rim of low signal was less common than in cerebral cavernous haemangiomas. In one case, the brain showed more than 20 lesions with the MRI appearances of cavernous haemangiomas. In two of five patients, serial preoperative MRI showed progressive disappearance of high-signal areas on both T1-and T2-weighted images. To find a haemorrhagic intramedullary lesion on MRI is not rare. Although the appearances are not pathognomonic, an IMCH can be suggested. We suggest that the following characteristics may help: (1) a personal and/or family history of cavernous haemangiomas; (2) typical MRI appearances of mixed acute, subacute and chronic haemorrhage; (3) a tendency for signal intensity to decrease on follow-up; (4) normal spinal angiography; and (5) associated brain lesions.
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  • 120
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 326-327 
    ISSN: 1432-1920
    Keywords: Osteoblastoma ; Skull ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated a 27-year-old woman with a retroauricular tumour. MRI revealed a signal void on T1- and T2-weighted images, and irregular enhancement with gadolinium-DTPA. The underlying dura mater also enhanced. The tumour was resected completely, and histological examination showed a benign osteoblastoma.
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  • 121
    ISSN: 1432-1920
    Keywords: Lumbar disc herniation ; Conservative treatment ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using serial MRI, we studied 32 patients with herniated lumbar discs, treated conservatively, to clarify the natural history of this condition. MRI was performed in the acute stage, then 6 months and 1 year later. On axial images, the proportion of the cross-sectional area of the spinal canal occupied by the herniated disc was 31.9% on the average on the initial scan, 28.7% 6 months and 25.3% 1 year later. The size of the herniation decreased by more than 20% in 11 patients (34%), by 10–20 % in 8 (28%) and was unchaged in 12 (38%). The height of the disc slightly decreased with time, but there was no significant change in the angle of lordosis in the affected segment. The initial MRI revealed degeneration of all affected discs, and progressive degeneration was observed in 9 patients. The more degenerate the disc and the larger the initial herniation the more the size of the herniated fragment decreased.
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  • 122
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 374-377 
    ISSN: 1432-1920
    Keywords: Spinal cord ; Magnetic resonance imaging ; Myelopathy ; Radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using MRI we assessed the changes in signal, size, and contrast enhancement characteristics of the cervical spinal cord in radiation myelopathy developing after radio-therapy for nasopharyngeal carcinoma. We studied two men and five women, aged 40–77 years. The first MRI study was performed 1–4 months after the initial clinical manifestations of myelopathy, and follow-up MRI 2–22 months after the onset of symptoms. On the first study, all patients showed low signal intensity in a long segment of the cervical spinal cord on T1-weighted images, high signal on T2*-weighted images, and focal contrast enhancement at C1-2. In five patients there was also swelling of the spinal cord. The site of eccentric focal contrast enhancement correlated with the clinical manifestations. Follow-up imaging less than 10 months after the onset of symptoms showed no significant changes in signal intensity. Focal contrast enhancement at C1–2 remained the same in three patients, was more dense and larger in one, and less dense in another. Subsidence of swelling was seen in two patients. Atrophy of the spinal cord at C1–2, without abnormal signal and with faint contrast enhancement at C1–2 was revealed as early as 10 months after the onset of symptoms, but the contrast enhancement disappeared by 22 months. There was no correlation between clinical manifestations and spinal cord atrophy on MRI.
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  • 123
    ISSN: 1432-1920
    Keywords: Myelopathy ; Demyelinating disease ; Multiple sclerosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of cerebral and spinal cord MRI was investigated in 65 patients with myelopathy suspected of having demyelinating disease. Cerebral MRI demonstrated lesions compatible with demyelination in 80% and spinal cord MRI in 68.6%. In 28.5% of our patients brain lesions were present with normal spinal cord images, but in 17% spinal cord lesions were depicted with a normal brain MRI. The combination of the two examinations demonstrated lesions in 97% of the patients. The frequency of coexistent cerebral lesions in patients with spinal cord lesions was over 85% in patients with chronic disease but only 28.5% in patients with acute myelitis.
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  • 124
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 331-333 
    ISSN: 1432-1920
    Keywords: Mineralizing microangiopathy ; Chemotherapy R ; Radiotherapy ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mineralizing microangiopathy, a distinctive histopathologic process involving the microvasculature of the central nervous system (CNS), is usually seen following combined radiation and chemotherapy for the treatment of CNS neoplasms in childhood. CT typically demonstrates calcification within the basal ganglia and subcortical white matter. The areas of calcification may give paradoxically increased signal on T1-weighted MRI due to a surface-relaxation mechanism, and decreased signal on T2-weighted images.
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  • 125
    ISSN: 1432-1920
    Keywords: Sinus thrombosis ; Reperfusion ; Cerebral infarction ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 50-year-old woman with idiopathic deep cerebral sinus and vein thrombosis (DCVT) had cerebellar disturbance prior to impaired consciousness. CT and MRI revealed haemorrhagic infarction in the cerebellum and signal changes suggesting infarction in the thalamus and basal ganglia bilaterally. The straight sinus and internal cerebral vein (ICV) were dense on CT. On angiography, the vein of Galen (VG) and straight sinus were not seen. Following clinical recovery, CT and MRI became normal, and angiography showed recanalization of the VG and ICV. The relationship between cerebellar infarction and DCVT, and signal changes on CT and MRI are discussed.
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  • 126
    ISSN: 1432-1920
    Keywords: Leukoencephalopathy ; White matter swelling ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In children, several neurological disorders are characterised by spongiform leukoencephalopathy. MRI of the brain typically shows white matter swelling, but does not enable differentiation of the various underlying disorders. The aim of this article is optimisation of the diagnostic value of MRI in leukoencephalopathy accompanied by swelling. MRI-based inclusion criteria were met by 20 patients in our database. The images were analysed using a detailed scoring list. In 13 of the 20 patients the clinical diagnosis was known (11 definite and 2 probable diagnoses). Characteristic MRI abnormalities could be defined in these patients. Of the 7 patients without a diagnosis, 5 had identical MRI abnormalities: difuse hemisphere swelling and typical cysts in frontoparietal subcortical white matter and the tips of the temporal lobes. The clinical picture was also similar in these patients, suggesting a similar disease.
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  • 127
    ISSN: 1432-1920
    Keywords: Key words Trigeminal neuralgia ; Magnetic resonance imaging ; MR tomographic angiography ; Vascular compression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A combination of MRI, MR angiography and MR tomographic angiography (MRTA) was used to study the relationship of the root exit zone of the trigeminal nerve to surrounding vascular structures in seven patients with trigeminal neuralgia (TN) and ten patients with no evidence at a lesion in this region. MRTA is the technique for showing the relationship between vessels, cranial nerves and brain stem. MRTA clearly demonstrated the presence of a vessel at the root exit zone of the trigeminal nerve in all patients with TN. In the ten other patients, examination of 20 trigeminal nerves revealed that only one nerve (5 %) was in contact with a vessel at the root exit zone. This study supports vascular compression of trigeminal nerves as a cause of TN, and demonstrates the value of MRTA as noninvasive technique for demonstrating compression.
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  • 128
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 649-652 
    ISSN: 1432-1920
    Keywords: Key words Carmofur ; 5-Fluorouracil ; Leukoencephalopathy ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Carmofur, a derivative of 5-fluorouracil, has recently been noted to have an infrequent but serious association with leukoencephalopathy. To our knowledge, there has been no report of early MRI findings in this leukoencephalopathy. We describe a case in which diffuse high signal intensity of the entire cerebral white matter, including the corpus callosum, was seen on T2-weighted magnetic resonance images. Although similar findings can be seen in many other diseases, carmofur-induced leukoencephalopathy should be suspected in a patient treated with carmofur. It is important to know the clinical and MRI characteristics of this condition, for early diagnosis and better prognosis.
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  • 129
    ISSN: 1432-1920
    Keywords: Key words Sinus thrombosis ; Reperfusion ; Cerebral infarction ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 50-year-old woman with idiopathic deep cerebral sinus and vein thrombosis (DCVT) had cerebellar disturbance prior to impaired consciousness. CT and MRI revealed haemorrhagic infarction in the cerebellum and signal changes suggesting infarction in the thalamus and basal ganglia bilaterally. The straight sinus and internal cerebral vein (ICV) were dense on CT. On angiography, the vein of Galen (VG) and straight sinus were not seen. Following clinical recovery, CT and MRI became normal, and angiography showed recanalization of the VG and ICV. The relationship between cerebellar infarction and DCVT, and signal changes on CT and MRI are discussed.
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  • 130
    ISSN: 1432-1920
    Keywords: Key words Laminectomy ; Adhesive arachnoradiculitis ; Magnetic resonance imaging ; Lumbar spine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Time-related changes of laminectomy-induced cauda equina adhesions were investigated by MRI in ten patients with degenerative spinal disease who underwent posterior surgery to the lumbar spine; seven had disc herniations and three spinal stenosis. Axial MRI was performed before and 3, 7, 21 and 42 days after surgery. Cauda equina adhesions were most severe at the laminectomised levels L3–4, L4–5 and L5–S1 (n = 16); partial adhesions were found in 9 of 16 levels at 6 weeks after surgery. At the L3–4 or L5–S1 levels (n = 14), the area of laminar exposure without laminectomy, the cauda equina adhesions continued 1 week after surgery, but thereafter resolved; only partial adhesions were seen at 5 of 14 levels 6 weeks after surgery. Shrinkage of the arachnoid sac was also found at the level of the laminectomy, but it re-expanded 3 weeks after surgery in all cases. Cauda equina adhesions and shrinkage of the sac were correlated closely with laminectomy, with or without discectomy, suggesting that an inflammatory process of deep wound healing may be involved in the mechanism of a laminectomy-induced arachnoradiculitis which may be correlated with postoperative leg symptoms.
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  • 131
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 453-455 
    ISSN: 1432-1920
    Keywords: Key words Cerebrospinal fluid ; Rhinorrhoea ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied two patients with spontaneous cerebrospinal fluid (CSF) rhinorrhoea with MRI and other imaging modalities. T2-weighted images proved most useful for the detection and localisation of the CSF leakage. MRI appeared to provide an accurate and noninvasive method for preoperative investigation of spontaneous CSF rhinorrhoea.
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  • 132
    ISSN: 1432-1920
    Keywords: Key words Idiopathic intracranial hypertension ; Visual loss ; Magnetic resonance imaging ; Blood-retinal barrier
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The case is reported of a patient with idiopathic intracranial hypertension examined with magnetic resonance imaging. Marked enhancement of the optic nerve heads was found, which might be related to blood-retinal barrier breakdown related to a sudden rise in intracranial cerebrospinal fluid pressure.
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  • 133
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    Neuroradiology 37 (1995), S. 465-467 
    ISSN: 1432-1920
    Keywords: Key words Leiomyosarcoma ; bone ; Spine ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present a 39-year-old man with tumour of the eighth thoracic vertebra, causing compression of the spinal cord. The tumour proved to be a primary leiomyosarcoma (LMS) of bone, an uncommon neoplasm; to our knowledge this is the first report of primary LMS in the spine. The lesion was documented by plain radiography, myelography, CT, MRI and digital subtraction angiography. These investigations did help to focus on the differential diagnosis and demonstrated the extent of the bony lesion, the findings were nonspecific, and the correct diagnosis was established by pathological examination.
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  • 134
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    Neuroradiology 37 (1995), S. 471-474 
    ISSN: 1432-1920
    Keywords: Key words Paranasal sinuses ; Incidental finding ; Interval change ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abnormal opacification of paranasal sinuses on brain MRI was studied in 178 consecutive adult patients who underwent two examinations separated by at least 4 months because of suspected neurological disease. Sinus abnormality was present in 79 (44 %) patients; in 60 % the abnormality involved two or more sinuses and it was bilateral in 51 %. The most frequently abnormal sinus was the maxillary (46 %), followed by the ethmoid (32 %), sphenoid (16 %), and frontal sinuses (6 %). Interval occurrence or complete resolution of abnormalities was observed in 52 % of patients (66 % of the sinuses). In the remaining 48 % of patients the abnormalities were present on two or more examinations, unchanged or of increased or decreased severity. The most frequent interval changing abnormalities were complete sinus opacification and fluid levels, followed by irregular mucoperiosteal thickening more than 4 mm thick. No polypoid abnormalities (polyps or mucosal cysts) decreased over time.
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  • 135
    ISSN: 1432-1920
    Keywords: Key words Idiopathic orbital inflammatory syndrome ; Orbital pseudotumour ; Fat saturation ; Gadolinium ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Idiopathic orbital inflammatory syndrome encompasses a group of inflammatory conditions for which no systemic or local cause can be found, and is commonly referred to as orbital pseudotumour. On conventional MRI sequences subtle areas of inflammation or enhancing tissue can easily be masked by the high signal intensity of orbital fat and involvement of the fat itself may not be appreciated. We describe the MRI features of three patients with idiopathic orbital inflammation using frequency-selective fat saturation and Gd-DTPA.
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  • 136
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    Neuroradiology 37 (1995), S. 481-485 
    ISSN: 1432-1920
    Keywords: Key words Brain ; neoplasms ; Gliofibroma ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe CT and MRI appearances in two children with pathologically proven gliofibromas, in the cerebrum and cerebellum. A striking finding was lack of high signal on T2-weighted MRI.
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  • 137
    ISSN: 1432-1920
    Keywords: Key words Hereditary motor and sensory neuropathy type III ; Sural nerve ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated two patients with hereditary motor and sensory neuropathy type III, one with Déjérine-Sottas disease and the other with congenital hypomyelination neuropathy based on nerve pathology and MRI of the sciatic nerve. On biopsy of the sural nerve of the patient with Déjérine-Sottas disease, myelin debris, indicating demyelination, was observed in an onion-bulb pattern surrounding myelinated fibres. In the patient with congenital hypomyelination neuropathy, onion bulbs were formed of two parallel layers of basement membrane. There was no evidence of myelin breakdown. On axial T2-weighted MRI, a severely hypertropied sciatic nerve containing multiple rounded lesions, suggesting inflammation or demyelination, was observed in the patient with Déjérine-Sottas disease. In contrast, the sciatic nerve of the patient with congenital hypomyelination neuropathy showed slight hypertrophy without demyelination. MRI of the sciatic nerve may represent a useful tool for characterisation of demyelinating disease and its prognosis.
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  • 138
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging ; Spatial autocorrelation ; Cerebral HIV disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study was carried out using MRI (proton density-and T2-weighted) on 16 HIV-negative controls, 9 symptom-free HIV-positive patients and 25 with CDC IV HIV disease. The studies from this last group had previously been allocated by a radiologist to the following categories: 8 with focal mass lesions and normal-appearing white matter; 9 with diffuse encephalopathy (high signal on T2-weighted images, affecting most or all of the white matter) and 8 with patchy encephalopathy (high signal affecting only one or two areas within the white matter). Moran'sI, a statistic of spatial autocorrelation, was calculated for the grey-scale values of a sampled pixel array from a central white matter region of each of the images. All values of Moran'sI calculated in this study showed a large positive excess over the expected value under randomisation, indicating highly significant positive autocorrelation in the spatial arrangement of the grey-scale values. On T2-weighted images a statistically significant increase in the mean value of Moran'sI, compared with controls, was found in the diffuse encephalopathy group, indicating that quantifiable changes in the spatial autocorrelation of pixel data can be related to recognised qualitative changes in the appearance of white matter in subjects with HIV disease. A lesser, but significant, rise in the mean value of Moran'sI was also found in the focal mass lesion group, suggesting that changes in spatial autocorrelation may indicate pathological change in advance of qualitative MRI changes.
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  • 139
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    Neuroradiology 37 (1995), S. 449-450 
    ISSN: 1432-1920
    Keywords: Pituitary Cryptococcosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe a rare pituitary cryptococcoma in an immunocompetent patient, with radiological features similar to those of a pituitary macroadenoma. Although unusual, it should be added to the list of differential diagnosis of pituitary masses. Contrast enhancement of adjacent meninges differentiated the lesion from an adenoma.
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  • 140
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    Neuroradiology 37 (1995), S. 438-439 
    ISSN: 1432-1920
    Keywords: Key words Progressive dysphasia ; Status epilepticus ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Status epilepticus is usually a straightforward diagnosis when a patient has two or more seizures without regaining consciousness. However, when status is nonconvulsive and, in particular, has a temporal lobe flavour the clinical presentation may be misleading. Presentation with automatic or psychic behaviour is well recorded. We report a patient with nonconvulsive status who presented with progressive dysphasia with widespread CT and MRI changes. The dysphasia and imaging changes led to a diagnosis of a probable neoplastic brain process but reversed with anticonvulsant treatment.
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  • 141
    ISSN: 1432-1920
    Keywords: Key words Acute disseminated encephalomyelitis ; Transplantation ; Magnetic resonance imaging ; FK-506 ; Rabbit antithymocyte globulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Acute disseminated encephalomyelitis (ADEM) is a white matter inflammatory disease which usually follows a viral infection or pharmaceutical intervention. We describe a case of presumed ADEM in a heart/lung transplant patient, the etiology of which cannot be elucidated. The fascinating aspect is the mode of clinical presentation and the rapid resolution of radiologic abnormalities. Histologic examination of the brain is provided in an attempt to elucidate the radiographic abnormalities.
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  • 142
    ISSN: 1432-1920
    Keywords: Creutzfeldt-Jacob disease ; Magnetic resonance imaging ; Prion protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a 66-year-old woman with histologically diagnosed Creutzfeldt-Jacob disease (CJD), followed with MRI from an early clinical stage. MRI demonstrated expansion of the high cortical signal on T2-weighted images, which differs from previous MRI reports of CJD. This patient followed an atypical clinical course: 16 months had passed before she developed akinetic mutism, and periodic sharp waves had not been detected on EEG after 2 years in spite of her akinetic mutism. Brain biopsy showed primary spongiform changes in the grey matter, and a point mutation of the prion protein gene at codon 180 was discovered using polymerase chain reaction direct sequencing and Tth 111 I cutting. This is the first case with the point mutation of the codon 180 variant with an atypical clinical course and characteristic MRI findings.
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  • 143
    ISSN: 1432-1920
    Keywords: Cholesterol granuloma ; Magnetic resonance imaging ; Middle cranial fossa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two cases of cholesterol granuloma in the middle cranial fossa. On CT the lesions appeared as a nonspecific, nonenhancing soft-tissue mass with bone erosion. On MRI they were seen as areas of high signal intensity surrounded by a low-intensity peripheral zone on both T1- and T2-weighted images. Cholesterol granuloma is thought to occur when pneumatised cellsin the temporal bone become obstructed. Although this lesion usually occurs in the petrous bone, it can extend to the middle cranial fossa. The diagnosis and surgical management are discussed.
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  • 144
    ISSN: 1432-1920
    Keywords: Lyme disease ; Magnetic resonance imaging ; Gadopentetate dimeglumine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the cranial CT and MRI findings in three children with Lyme disease (neuroborreliosis). The neuroimaging findings in children have been rarely reported. We found cranial MRI far superior to cranial CT. Ring-enhancing lesions have been described in acute disseminating encephalomyelitis and multiple sclerosis but not in neuroborreliosis. Although orther infectious and inflammatory diseases cannot be excluded, Lyme disease should be included in the differential diagnosis and put forward as being the most likely diagnosis in the appropriate clinical setting. Gadopentetate dimeglumine is helpful in assessing the response to antibiotic treatment.
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  • 145
    ISSN: 1432-1920
    Keywords: Key words Meninges ; Contrast enhancement ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe thickening and contrast enhancement of the intracranial pachymeninges, revealed by MRI in a patient with presumed low-pressure headache following dural puncture and a blood patch. The clinical and radiological abnormalities resolved within 2 weeks.
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  • 146
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    Neuroradiology 37 (1995), S. 559-560 
    ISSN: 1432-1920
    Keywords: Key words Cervical spine ; Spondylolysis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a case of cervical spondylolysis, unusual in that it was associated with spinal cord compression.
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  • 147
    ISSN: 1432-1920
    Keywords: Key words Cholesterol granuloma ; Magnetic resonance imaging ; Middle cranial fossa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two cases of cholesterol granuloma in the middle cranial fossa. On CT the lesions appeared as a nonspecific, nonenhancing soft-tissue mass with bone erosion. On MRI they were seen as areas of high signal intensity surrounded by a low-intensity peripheral zone on both T1- and T2-weighted images. Cholesterol granuloma is thought to occur when pneumatised cells in the temporal bone become obstructed. Although this lesion usually occurs in the petrous bone, it can extend to the middle cranial fossa. The diagnosis and surgical management are discussed.
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  • 148
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    Neuroradiology 38 (1995), S. 44-46 
    ISSN: 1432-1920
    Keywords: Key words Skull amyloidoma ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Amyloidomas involving bone are rare. The 67-year-old man reported here had a large amyloidoma of the left frontal, parietal, sphenoid (greater wing) and temporal bones causing neural compression. Plain radiographs CT and MRI are shown.
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  • 149
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    Neuroradiology 38 (1995), S. 41-43 
    ISSN: 1432-1920
    Keywords: Key words Osteochondroma ; Skull base ; Computed tomography ; Magnetic resonance imaging ; Fat suppression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A skull base osteochondroma (benign exostosis) in a 38-year-old man is reported. MRI was not only very useful for determining the extent of the tumour, but also showed its fat content and, on contrast-enhanced fat-suppressed images, its vascularity.
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  • 150
    ISSN: 1432-1920
    Keywords: Key words Internal auditory canal ; Acoustic schwannoma ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Prospective baseline MRI was obtained on 31 patients who had “total” removal of acoustic schwannoma 6 months to 9 years previously. Follow-up MRI was performed after 1–2 years on patients with questionable abnormalities. We found four patterns (1) internal auditory canals (IAC) with nonenhancing soft-tissue strands, possibly scars or distorted residual nerves (8); (2) IAC with marginal enhancement-reactive dura mater (16); (3) IAC with contrast-enhancing globular tissues suggesting residual or recurrent tumour (5); (4) high-signal intensity in the IAC before contrast medium administration, probably related to graft with fat/fascia/muscle (2). Prospective 1- to 2-year follow-up studies were available in 8, 5, and 1 patients in groups 2, 3, and 4 respectively. In group 2, dural enhancement remained unchanged in 5 patients and decreased in 3. In group 3 follow-up showed 1 tumor recurrence (surgically confirmed) and 4 stable abnormalities. In group 4, follow-up in 1 of the 2 patients was stable. In groups 1 and 2, the MRI features correlate well with complete tumor removal. Whether follow-up in these groups is indicated needs to be determined. In group 3 residual or recurrent tumor cannot be excluded. In group 4, grafts may prevent adequate visualization of the IAC.
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  • 151
    ISSN: 1432-1920
    Keywords: Laminectomy ; Adhesive arachnoradiculitis ; Magnetic resonance imaging ; Lumbar spine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Time-related changes of laminectomy-induced cauda equina adhesions were investigated by MRI in ten patients with degenerative spinal disease who underwent posterior surgery to the lumbar spine; seven had disc herniations and three spinal stenosis. Axial MRI was performed before and 3, 7, 21 and 42 days after surgery. Cauda equina adhesions were most severe at the laminectomised levels L3-4, L4-5 and L5-S1 (n=16); partial adhesions were found in 9 of 16 levels at 6 weeks after surgery. At the L3-4 or L5-S1 levels (n=14), the area of laminar exposure without laminectomy, the cauda equina adhesions continued 1 week after surgery, but thereafter resolved; only partial adhesions were seen at 5 of 14 levels 6 weeks after surgery. Shrinkage of the arachnoid sac was also found at the level of the laminectomy, but it re-expanded 3 weeks after surgery in all cases. Cauda equina adhesions and shrinkage of the sac were correlated closely with laminectomy, with or without discectomy, suggesting that an inflammatory process of deep wound healing may be involved in the mechanism of a laminectomy-induced arachnoradiculitis which may be correlated with post-operative leg symptoms.
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  • 152
    ISSN: 1432-1920
    Keywords: Key words Pineal region tumours ; Magnetic resonance imaging ; Germ cell tumours ; Pineal cell tumours ; Meningiomas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A variety of tumours may arise in the pineal region; accurate diagnosis is important in the selection of treatment and prognosis. A retrospective analysis of the MRI studies of 25 patients with pathologically proven pineal region tumours was performed, focused on the relationship between the tumour and neighbouring structures. Compression of the tectal plate was classified as expansive or invasive, and compression of the corpus callosum as inferior, anterior or posterior. In 10 of the 14 patients (71 %) with germ cell tumours tectal compression was of the invasive type; 8 patients (57 %) had multiple tumours and in 13 (93 %) the tumour margins were irregular. Teratomas were readily diagnosed because of characteristic heterogeneous signal intensity. Pineal cell tumours were differentiated from germ cell tumours by their rounded shape, solid nature, sharp margins, and expansive type of tectal compression. Meningiomas were characterised by their falcotentorial attachments, posterior callosal compression, and a low-intensity rim on T2-weighted images. Gd-DTPA injection enabled clear demonstration of the site and extent of tumour spread and was useful in differentiating cystic and solid components. The appearances described, while not pathognomonic, are helpful in the differential diagnosis of pineal region tumours, and valuable in planning appropriate treatment.
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  • 153
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    Neuroradiology 37 (1995), S. 631-635 
    ISSN: 1432-1920
    Keywords: Key words Tissue characterisation ; Carotid artery ; Atheromatous plaque ; Intramural haemorrhage ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Carotid artery plaques with intraplaque haemorrhage or atheromatous debris have been found to be associated with an increased risk of embolic stroke. Other methods have failed to detect plaque morphology, and it is not clear whether MRI allows differentiation between prognostically and therapeutically relevant plaque types. We examined 17 carotid bifurcation plaques which had been removed in toto by MRI. For quantifying MR signal intensities (I) the contrast-to-noise ratio (CNR) was used: (ITissue– IRef) / SDRef, with normal saline (0.9 %) as reference (Ref) and the standard deviation (SD) of the noise. Measurements were correlated with the histopathological appearance of “simple plaques”, consisting of fibrous intimal thickening, lipid deposits and/or atheromatous tissue with cholesterol crystals, largely calcified plaques, and “complicated plaques”, containing recent intramural haemorrhage or friable atheromatous debris. Significantly different mean CNR could be measured in the three plaque types on T1- and T2-weighted sequences (p 〈 0.00001) and using the FLASH pulse sequence with a flip angle of 15 ° (p 〈 0.001). With the T1-weighted sequence simple plaques showed a CNR of 4.4 ± 2.3, calcified plaques −4.8 ± 2.6 and complicated plaques 15.1 ± 4.3. Using this technique, each single plaque could be correctly classified, an unalterable prerequisite for a clinical application. To date, motion artefacts due to patient movement or insufficiently triggerable vessel pulsation in combination with relative long acquisition times (6–7 min) have limited in vivo investigations. If these problems could be overcome, MRI might become a valuable technique for studying carotid plaque morphology.
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  • 154
    ISSN: 1432-1920
    Keywords: Key words Myelopathy ; Demyelinating disease ; Multiple sclerosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of cerebral and spinal cord MRI was investigated in 65 patients with myelopathy suspected of having demyelinating disease. Cerebral MRI demonstrated lesions compatible with demyelination in 80 % and spinal cord MRI in 68.6 %. In 28.5 % of our patients brain lesions were present with normal spinal cord images, but in 17 % spinal cord lesions were depicted with a normal brain MRI. The combination of the two examinations demonstrated lesions in 97 % of the patients. The frequency of coexistent cerebral lesions in patients with spinal cord lesions was over 85 % in patients with chronic disease but only 28.5 % in patients with acute myelitis.
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  • 155
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    Neuroradiology 37 (1995), S. 443-444 
    ISSN: 1432-1920
    Keywords: Key words Chronic thinner intoxication ; Magnetic resonance imaging ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied a 19-year-old man with thinner and toluene poisoning for 5 years by CT and MRI. Symmetrical lesions were seen in the basal ganglia and cingulate gyri.
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  • 156
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    Neuroradiology 37 (1995), S. 449-450 
    ISSN: 1432-1920
    Keywords: Key words Pituitary ; Cryptococcosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe a rare pituitary cryptococcoma in an immunocompetent patient, with radiological features similar to those of a pituitary macroadenoma. Although unusual, it should be added to the list of differential diagnosis of pituitary masses. Contrast enhancement of adjacent meninges differentiated the lesion from an adenoma.
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  • 157
    ISSN: 1432-1920
    Keywords: Key words Leukoencephalopathy ; White matter swelling ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In children, several neurological disorders are characterised by spongiform leukoencephalopathy. MRI of the brain typically shows white matter swelling, but does not enable differentiation of the various underlying disorders. The aim of this article is optimisation of the diagnostic value of MRI in leukoencephalopathy accompanied by swelling. MRI-based inclusion criteria were met by 20 patients in our database. The images were analysed using a detailed scoring list. In 13 of the 20 patients the clinical diagnosis was known (11 definite and 2 probable diagnoses). Characteristic MRI abnormalities could be defined in these patients. Of the 7 patients without a diagnosis, 5 had identical MRI abnormalities: diffuse hemisphere swelling and typical cysts in frontoparietal subcortical white matter and the tips of the temporal lobes. The clinical picture was also similar in these patients, suggesting a similar disease.
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  • 158
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    Neuroradiology 38 (1995), S. 47-49 
    ISSN: 1432-1920
    Keywords: Key words Nelson's syndrome ; Cavernous sinus ; Infarct ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the MRI appearances of an infarcted cavernous sinus tumor in a patient with Nelson's syndrome. Invasive tumors of the pituitary extending to the cavernous sinus are discussed and the role of MRI in preoperative investigation is highlighted.
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  • 159
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    Neuroradiology 38 (1995), S. 38-40 
    ISSN: 1432-1920
    Keywords: Key words Cerebellopontine ; angle ; Choroid plexus papilloma ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present a cerebellopontine angle choroid plexus papilloma that originated from the tuft of choroid plexus of the fourth ventricle protruding from the foramen of Luschka. MRI and CT did not establish the diagnosis, but the tumor was shown histopathologically to be a choroid plexus papilloma. Distinct features of the tumor on MRI are described and the differential diagnosis of other cerebellopontine angle tumors is discussed.
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  • 160
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    Pediatric cardiology 16 (1995), S. 48-50 
    ISSN: 1432-1971
    Keywords: Cardiac tumor ; Hemangiopericytoma ; Infant ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A male infant with benign hemangiopericytoma of the right atrium is reported. His chief complaint was acute respiratory distress secondary to bloody pericardial effusion. Although the entire mass could not be removed surgically, there was no recurrence of cardiac tamponade or growth of the residual mass during a follow-up period of 3 years. This patient is, to our knowledge, the youngest one with primary cardiac hemangiopericytoma so far reported.
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  • 161
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    Pediatric nephrology 9 (1995), S. 247-249 
    ISSN: 1432-198X
    Keywords: Nephrotic syndrome ; Cerebral venous thrombosis ; Diagnosis ; Treatment ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
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  • 162
    ISSN: 1432-1920
    Keywords: Key words Meningioangioma-tosis ; Magnetic resonance imaging ; Malignant meningioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Meningioangiomatosis (MA) is a rare benign intracranial tumour of uncertain pathogenesis, with only 33 cases reported in the literature. Imaging features have been described in 21 cases, only 3 with contrast-enhanced MRI. We present two cases of MA with MRI and/or CT findings and gross, ultrastructural, and immunohistochemical characteristics. MRI is particularly helpful for establishing the origin of the lesion and its anatomical location, while CT shows calcification, if present. The pathological characteristics establish the diagnosis and underline the differences from other entities such as malignant meningioma, one of the most important differential diagnostic considerations.
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  • 163
    ISSN: 1432-1920
    Keywords: Ependymoma ; Posterior cranial fossa ; Children ; Magnetic resonance imaging ; Computed tomography ; Brain tumours
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied nine children with posterior cranial fossa ependymomas to identify specific neuroradiological features. Patients were studied preoperatively with CT and MRI; T1-, T2-and proton-density (PD)-weighted images were obtained. All children underwent surgery and a definite histopathological diagnosis was made. All the tumours grew into the fourth ventricle and caused dilatation of its upper part, which resembled a cap. All but one were separated from the vermis by a cleavage plane. In eight cases there was desmoplastic development through the foramina of the fourth ventricle, and five were heterogeneous due to necrosis and cystic change; one had a haemorrhagic area. In most cases the solid portion was isointense with grey matter on T1-weighted images, hyperintense on PD weighting, and isointense on T2-weighted images. On CT the tumour was isodense in six cases and calcification was detected in four. The presence of both desmoplastic development and a tumour/vermis cleavage plane in a posterior cranial fossa tumour isodense on CT is highly suggestive of ependymoma.
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  • 164
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    Pediatric cardiology 16 (1995), S. 291-293 
    ISSN: 1432-1971
    Keywords: Innominate vein ; Brachiocephalic artery anomaly ; Angiocardiography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An unique case of left innominate vein compression by a leftward origin of a brachiocephalic artery in conjunction with an aberrant right subclavian artery anomaly occurred in a young patient. Aortography and magnetic resonance imaging were invaluable in arriving at a diagnosis.
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  • 165
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    European archives of psychiatry and clinical neuroscience 245 (1995), S. 142-144 
    ISSN: 1433-8491
    Keywords: Magnetic resonance imaging ; Schizophrenia ; Asymmetry of the lateral ventricle ; Age at the onset of illness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationship between lateral ventricular size or its asymmetry and age at the onset of schizophrenia was investigated in 20 schizophrenic patients diagnosed according to DSM-III-R criteria. The ventriclebrain ratio (VBR) was determined using three transaxial slices of magnetic resonance image (MRI) and asymmetry of the lateral ventricle was evaluated from the laterality index of the lateral ventricular area: (left-right/lef+right)×100. Each age at the onset of the prodromal and active phase according to DSM-III-R criteria was determined for each patient. The results showed that asymmetry of the ventricle, but not VBR, was significantly correlated inversely with age at the onset of both the prodromal phase and active phase. Neither asymmetry nor VBR correlated with the duration of illness, age at MRI scanning, or severity of clinical symptoms. It would thus appear that greater asymmetry of the ventricle is associated with earlier onset of schizophrenia.
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  • 166
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    Child's nervous system 11 (1995), S. 112-114 
    ISSN: 1433-0350
    Keywords: Menkes' disease ; Copper deficiency ; Pili torti ; Magnetic resonance imaging ; Skeletal roentgenography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Menkes' disease, a neurodegenerative progressive X-linked disorder, was diagnosed in a 4-month-old child. The diagnosis was made on the combination of clinical features with laboratory and radiological findings. The pathogenesis of the skeletal findings in Menkes' disease is as yet unclear. Because of the severity of the prognosis and in order to plan treatment, the correct diagnosis has to be reached quickly. Typical manifestations of the syndrome are likely to develop after 3 months of age, with a pleiotropic appearance. In the present case, on the basis of the clinical investigation the patient underwent retrograde cystourethrography, roentgenographic examination of the skeleton, and magnetic resonance imaging of the brain. On analysis of the magnetic resonance imaging, we detected one-sided involvement of both subcortical and cortical parenchyma resembling a unilateral ischemic lesion such as, to our knowledge, has not yet been reported.
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  • 167
    ISSN: 1433-0350
    Keywords: Magnetic resonance imaging ; Cerebellitis ; Ataxia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present a sequence of magnetic resonance images (MRI) of a patient with cerebellitis, taken from the onset of symptoms until their disappearance 9 months later. The need to perform MRI rather than computed tomography in all patients suspected of having cerebellitis or other posterior fossa lesions is suggested
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  • 168
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    Child's nervous system 11 (1995), S. 227-230 
    ISSN: 1433-0350
    Keywords: Cerebrospinal fluid ; Magnetic resonance imaging ; Bulk flow ; To-and-fro movement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Analysis of cerebrospinal fluid (CSF) flow and motion at the craniospinal junction was conducted by magnetic resonance velocity imaging with phase encoding followed by motion velocity intergration. Thirteen normal subjects classified into two groups were studied: an infant group with open sutures and fontanel, and a noninfant group with closed sutures and fontanel. Predominance in CSF to-and-fro motion was recognized in the ventral subarachnoid space, and a maximum caudad motion velocityof 7.5±2.4 mm/s was recorded in the infant group and one of 14.9±6.2 mm/s in the noninfant group. The average bulk flow velocity in all cases was 86.7±81.6 (means±SD) mm/min. The difference in flow velocity between the infant group (19.7±28.2 mm/min) and the noninfant group (116.5±80 mm/min) suggested that the CSF circulation around the cervical spine may vary at different ages.
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  • 169
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    Child's nervous system 11 (1995), S. 242-245 
    ISSN: 1433-0350
    Keywords: Cranial fasciitis ; Nodular fasciitis ; Childhood ; Intracranial involvement ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The case of a 10-monthold boy with cranial fasciitis is described. The patient had a rapidly growing subcutaneous mass in the left frontotemporal region. Computed tomography and magnetic resonance imaging clearly demonstrated a mass in the left temporoparietal bone extending both intra-and extracranially. The tumor seemed to originate from the calvarium, being located between the periosteum and the dura mater. Total resection of the tumor was performed, and the tumor was histologically identified as cranial fasciitis. A brief review of the literature is included that emphasizes the need for further investigation of this benign lesion that is frequently confused with a malignant neoplasm.
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  • 170
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    Child's nervous system 11 (1995), S. 329-334 
    ISSN: 1433-0350
    Keywords: Moyamoya disease ; Magnetic resonance imaging ; Magnetic resonance angiography ; Cerebral angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Spontaneous occlusion of the circle of Willis, i.e., moyamoya disease (MMD), is a clinical disease entity angiographically characterized by progressive and bilateral stenosis of the carotid bifurcation, with a hazy collateral network at the base or convexity of the brain. Although the importance of computed tomography (CT) and conventional magnetic resonance (MR) imaging in diagnosing MMD has already been determined, conventional arteriography is still regarded as necessary for definitive diagnosis. Magnetic resonance angiography (MR-A) is a very recent vascular imaging technique which allows noninvasive and direct imaging of vessels without the use of contrast medium. We present four pediatric cases of MMD, evaluated by conventional angiography, CT, MR imaging, and MR-A. Our data demonstrate thatMR-A is successful both in allowing detection of occlusive disease of the basal portion of the internal carotid artery and large branch basal cerebral vessels and demonstrating the collateral vessels at the base of the brain. As a noninvasive procedure, MR-A promises to become a valuable alternative to classical angiography in the diagnosis of MMD.
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  • 171
    ISSN: 1432-2161
    Keywords: Arthritis ; Rat ; Knee ; Magnetic resonance imaging ; Radiography ; Histology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract High-resolution magnetic resonance imaging (MRI) was used to investigate antigen-induced monoarticular arthritis (AIMA) in the rat. In sagittal, spin-echo images of the knee, characteristic parallel bands, in the order dark-light-dark, were consistently observed 5–8 days after arthritis induction; the bands ran concentric with, and just beneath, the femoral and tibial articular surfaces. Concurrent radiology, histology and MRI (chemical shift-selective imaging and contrast enhancement with magnetisation transfer and gadolinium) established that the phenomenon reflected subchondral erosion, not artefact. The outer hypointense band corresponded to calcified cartilage underlying the articular surface. The central hyperintense band reflected inflammatory matrix displacing normal haematopoietic tissue immediately subchondrally; here, trabecular bone had mostly disappeared, but adjacent articular cartilage, although under attack and lacking proteoglycan, appeared structurally normal. The inner hypointense band reflected deeper, truncated trabeculae within inflammatory matrix, layered with pallisading osteoblast-like cells. This study exemplifies the power of MRI for revealing localised joint pathology non-invasively, and shows that rat AIMA shares many pathological features with arthritis in human beings.
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  • 172
    ISSN: 1432-2161
    Keywords: Magnetic resonance imaging ; Gd-DTPA ; Contrast medium enhancement ; Rheumatoid arthritis ; Seronegative spondyloarthritis ; Differential diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A series of patients with clinically early inflammatory joint disease due to rheumatoid arthritis, psoriatic arthritis and Reiter's syndrome were examined by plain film radiography and magnetic resonance imaging (MRI). The spin echo T1-weighted precontrast, T2-weighted, and, especially, T1-weighted postcontrast images demonstrated distinct differences in the distribution of inflamatory changes, both within and adjacent to involved small hand joints. Two major subtypes of inflammatory arthritis were shown, thus providing a specific differential diagnosis between rheumatoid arthritis and some patients with seronegative spondyloarthritis. In particular, all the patients with Reiter's syndrome who were studied, and half of those with psoriatic arthritis, had a distinctive pattern of extra-articular disease involvement. The need for a new classification of clinical subsets in psoriatic arthritis has been recently suggested. The present findings suggest that magnetic resonance imaging could be useful in such a reclassification of seronegative spondyloarthritis, as well as offering considerable potential for a reappraisal of pathogenesis and therapy. In this series, it was also noted that juxta-articular osteoporosis on plain film did not correlate with bone marrow oedema on MRI. Hence the aetiology of this common radiographic finding also merits further consideration.
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  • 173
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    Skeletal radiology 24 (1995), S. 601-604 
    ISSN: 1432-2161
    Keywords: Muscle hernias ; Peroneus longus ; Fascial defects ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Herniation of the left peroneus longus muscle was present in three male members of the same family, being the first reported case of this condition in a familial setting. The hernias were differentiated from other mass lesions and varices by magnetic resonance imaging. The images demonstrated a fascial defect originating in the area where vessels and nerves penetrate the fascia, suggesting that the three men had a congenital weakness in the fascia.
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  • 174
    ISSN: 1432-2161
    Keywords: Vascular lesions ; Hemangioma ; Synovial hemangioma ; Soft tissue tumors ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective This study was undertaken to describe the imaging characteristics of synovial hemangioma, with the goal of improving the disappointing rate (22%) of clinical diagnosis of this condition. A review of the literature and the differential diagnosis of intra-articular lesions, including synovial osteochondromatosis and pigmented villonodular synovitis, are also presented. Patients The subjects of the study were 8 patients (4 males, 4 females; age range: 5–47 years; mean age: 19 years) with histologically confirmed synovial hemangioma involving the knee (n=7) or wrist (n=1). We retrospectively examined the imaging studies performed in these patients, including plain radiography (n=8), magnetic resonance imaging (MRI; n=4), angiography (n=3), arthrography (n=2), and contrast-enhanced computed tomography (CT; n=2). Results Plain radiographs showed a soft tissue density suggesting either joint effusion or a mass in all patients. Phleboliths and bone erosions on plain films in four patients with extra-articular soft tissue involvement pointed to the correct diagnosis. Angiography, showing fine-caliber, smooth-walled vessels, contrast pooling in dilated vascular spaces, and early visualization of venous structures, was diagnostic in two patients. Neither arthrography nor CT yielded specific enough findings. MRI was consistently effective in allowing the correct diagnosis to be made preoperatively, showing an intra-articular or juxta-articular mass of intermediate signal intensity on T1-weighted images and of high signal intensity on T2or T2*-weighted images with low-signal channels or septa within it. A fluid-fluid level was found in two patients with a cavernous-type lesion. Conclusion Despite the limited nature of this study, it shows clearly that MRI is the procedure of choice whenever an intra-articular vascular lesion such as synovial hemangioma is suspected. Nonetheless, phleboliths and evidence of extra-articular extension on plain radiographs point to angiography as an effective procedure of first resort because it can be combined with embolotherapy.
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  • 175
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    Skeletal radiology 24 (1995), S. 37-41 
    ISSN: 1432-2161
    Keywords: Intraosseous lipoma ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Four patients with intraosseous lipomas were studied with magnetic resonance imaging. The imaging features and histology of each tumor were compared. Magnetic resonance imaging was very helpful in establishing a pathologic diagnosis. If a severe degree of involution was present, then the magnetic resonance findings could be ambiguous, making diagnosis more difficult.
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  • 176
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    Skeletal radiology 24 (1995), S. 123-126 
    ISSN: 1432-2161
    Keywords: Patellar tendon ; Magnetic resonance imaging ; Gradient echo (GRE) sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thickening of the patellar tendon and foci of increased signal intensity have been described as characteristic features of “jumper's knee” (chronic patellar tendinitis) on magnetic resonance imaging (MRI). It was our impression that such appearances may be seen in the patellar tendons of patients without symptoms referable to the anterior part of the knee when using gradient echo images. The appearances of the asymptomatic patellar tendon on three-dimensional gradient echo sequences were studied by retrospectively reviewing the images of 60 patients, none of whom had symptoms related to the anterior part of the knee. The anteroposterior width of the patellar tendon was measured at three levels (superior, middle and inferior) on the central sagittal image of a gradient echo sequence. The relative signal intensities at the same levels were recorded. In 97% of subjects the superior part of the tendon was wider than the midpoint, and in 97% the inferior part was wider than the midpoint. The range of widths was wide, and there was no significant difference between sexes. Focal increased signal intensity in the superior part was shown in 75%, and in the inferior part in 43%. The asymptomatic patellar tendon shows uniform thickness throughout most of its length, but there are focal expansions at the proximal and distal ends. It usually demonstrates low signal on MRI, but may contain foci of increased signal intensity at either or both ends when imaged on gradient-echo sequences.
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  • 177
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    Skeletal radiology 24 (1995), S. 399-408 
    ISSN: 1432-2161
    Keywords: Spondyloarthropathy ; Juvenile ankylosing spondylitis ; Juvenile psoriatic arthritis ; Arthritis with IBD ; Reiter's syndrome ; Reactive arthritis ; Enthesitis ; Sacroiliitis ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The spondyloarthropathies comprise four distinct entities — ankylosing spondylitis, psoriatic arthritis, the arthritis associated with inflammatory bowel disease, and Reiter's syndrome and other related forms of reactive arthritis. Although these are distinct diseases, they have a number of clinical, radiologie, and genetic characteristics in common which permit them to be classified under the unifying term “spondyloarthropathy”. They are diseases of young adults, and when they present in patients under 16 years of age we refer to them as the “juvenile” spondyloarthropathies. They must be distinguished from juvenile rheumatoid arthritis, which is a totally separate entity; however the distinction may not always be obvious. Involvement of peripheral and sacroiliac joints commonly occurs in the juvenile spondyloarthropathies. The peripheral arthritis may be erosive and associated with bone apposition at the joint margins. Axial involvement is usually a late finding. Dactylitis and tenosynovitis are frequently present early on. Enthesitis, a highly specific feature, occurs much more often in the juvenile spondyloarthropathies than in the adult forms and it may be the only presenting feature. The plain radiograph is the primary and most important imaging modality for the assessment of these diseases. However, an expanding role of magnetic resonance imaging is evident.
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  • 178
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    Skeletal radiology 24 (1995), S. 579-581 
    ISSN: 1432-2161
    Keywords: Magnetic resonance imaging ; Knee ; Synovial hemangioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The findings in two patients with histologically proven synovial hemangioma of the knee are described. Both cases emphasize the typical appearance of this unusual tumor on magnetic resonance imaging. Additional radiologic findings, such as adjacent osseous involvement, are discussed.
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  • 179
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    Skeletal radiology 24 (1995), S. 543-545 
    ISSN: 1432-2161
    Keywords: Meniscus ; Meniscal ossicle ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the MR appearance of a meniscal ossicle, which is an unusual etiology for knee pain. The role of MR in differentiating a meniscal ossicle from a loose body is presented. The MR images also demonstrated associated tibial cartilage thinning and a possible meniscal tear. These MR findings led to arthroscopic treatment rather than conservative management. A review of the literature on meniscal ossicles is also presented.
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  • 180
    ISSN: 1432-2161
    Keywords: Alveolar soft part sarcoma ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective The objective of this study was to analyze the characteristics of alveolar soft part sarcoma using magnetic resonance imaging (MRI). Design MRI studies of pathologically proven alveolar soft part sarcomas (ASPS) in ten patients were reviewed and compared with computed tomographic (CT) studies and angiograms. Patients Ten patients presented with a soft tissue mass of the extremities, neck, axilla, or buttocks. MR images were obtained in all patients prior to surgical intervention, chemotherapy, or irradiation. Results and Conclusion Although most soft tissue sarcomas are isointense relative to muscle on MRI T1-weighted images (T1WI), nine of the ten alveolar ASPS in the present study demonstrated high signal intensity on both T2 and T1WI. Flow voids were observed both at the core and at the margins of the tumors studied. Recognition of these characteristic MRI findings may lead to the early diagnosis of ASPS, especially when the clinical presentation is that of a slow-growing soft tissue mass in a young adult patient.
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  • 181
    ISSN: 1432-2161
    Keywords: Elbow ; Osteonecrosis ; Osteochondritis dissecans ; Magnetic resonance imaging ; Gadopentetate dimeglumine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetic resonance imaging (MRI) was performed on seven patients with aseptic osteonecrosis (n=4) and osteochondritis dissecans (OCD;n=3) of the elbow. Precontrast MRI was superior to plain radiographs, which did not show any abnormality in three cases of osteonecrosis. On gadopentetate-dimeglumine-enhanced T1-weighted images, which were obtained in three patients with osteonecrosis and three patients with OCD, all cases of osteonecrosis demonstrated homogeneous enhancement of the lesions. All cases of OCD were diagnosed on plain radiographs. On MRI one showed significant enhancement of the loose body. In another case an incompletely enhancing loose body was surrounded by a diffusely enhancing region. In the third patient only a small marginal enhancement of the defect was observed. Our results suggest that MRI can improve the accuracy in diagnosis of aseptic osteonecrosis of the elbow. The use of gadopentetate dimeglumine allows the viability of the lesions or the loose bodies to be demonstrated and reparative tissue to be detected.
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  • 182
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    Skeletal radiology 24 (1995), S. 117-121 
    ISSN: 1432-2161
    Keywords: Glenoid labrum ; Magnetic resonance imaging ; Three-dimensional volume scan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of this study was to assess the accuracy of three-dimensional (3D) magnetic resonance imaging (MRI) reformation in the evaluation of tears of the glenoid labrum complex (GLC). Fifty-five shoulders were evaluated by MRI using standard spin-echo sequences. Gradient-refocused-echo axial projections were used to assess the GLC on the two-dimensional (2D) studies. Three-dimensional Fourier transform multiplanar gradient-recalled imaging with a resolution of 0.7 mm was also performed in all patients. Independent analyses of the anterior and posterior labra were performed in a blinded manner for both the 2D and 3D studies by three experienced musculoskeletal radiologists. Observations of the imaging studies were compared with the videoarthroscopic findings. The appearance of the GLC was rated on a scale of 0 to 4 (0–2=normal, 3, 4=abnormal or torn). The diagnostic confidence was averaged from the three reader's scores. Anterior labral tears were effectively detected with sensitivities of 89% and 96% and specificities of 96% and 100% (P〈0.0001) for the 2D and 3D studies, respectively. For posterior labral tears, the sensitivity and specificity of the 2D method were 47% and 98%, respectively. The sensitivity and specificity of the 3D volume sequence were 53% and 98%, respectively. The lower sensitivity of both imaging methods for detecting posterior labral tears may be influenced by the smaller number (n=5) of arthroscopically confirmed cases in our study and reflects the difficulty of viusalizing the posteroinferior borders of the GLC with present MRI techniques.
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  • 183
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    Skeletal radiology 24 (1995), S. 437-440 
    ISSN: 1432-2161
    Keywords: Cat scratch disease ; Infectious lymphaden ; opathy ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cat scratch disease is an infectious lymphadenitis frequently occurring in children and adolescents. We present the magnetic resonance imaging findings of two patients with this disease. In both cases, lymphadenopathy was characterized by extensive stranding of the surrounding soft tissues, consistent with the inflammatory nature of this condition. Magnetic resonance imaging can be diagnostic and may obviate the need for invasive means of evaluation in patients suspected of having cat scratch disease.
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  • 184
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    Skeletal radiology 24 (1995), S. 511-514 
    ISSN: 1432-2161
    Keywords: Magnetic resonance imaging ; Injuries ; Tendons ; Muscles ; Popliteus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective. Popliteal muscle and tendon injuries are thought to be unusual. This report describes the magnetic resonance (MR) appearances of popliteus muscle and tendon injuries. Design and patients. The study included 24 patients where the diagnoses of popliteal injuries were prospectively made based on MR appearances. The study group was taken from 2412 consecutive knee MRIs. The injuries were characterized as to involving the muscular or tendinous portions of the popliteus apparatus. Results. In 95.8% (23/24) of patients, the tears of the popliteus involved the muscular portion. The injuries were either partial and interstitial or complete. Three patients had tears of both the muscular and tendinous portions or the tendon alone. The anterior and posterior cruciate ligaments were torn in 16.7% (4/24) and 29.2% (7/24) of patients, respectively. There were medial and lateral meniscal tears in 45.8% (11/24) and 25% (6/24) of patients, respectively. There were injuries of the medial and lateral collateral ligaments in 8.3% (2/24) and 4.2% (1/24) of patients, respectively. Bone bruises and/or fractures were seen in 33.3% (8/24) patients. In 8.3% (2/24) of patients, the popliteus injury was an isolated finding. Conclusion. Popliteus muscle and tendon injuries are not uncommon. They usually occur in conjunction with other significant injuries of the knee and can be characterized with MR imaging.
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  • 185
    ISSN: 1435-2451
    Keywords: Hyperextension injury ; Lower cervical spine ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Kasuistik beinhaltet 5 Patienten mit Hyperextensionsverletzungen der unteren Halswirbelsäule (HWS). Die dorsale Instabilität in einem Bewegungssegment war im HWS-Röntgen nicht eindeutig zu verifizieren. Die Funktionsaufnahmen zeigten 4mal eine leichte Retrospondylolisthesis von 2 mm and 1mal eine mäßige Erweiterung des Zwischenwirbelraums. Die Mangnetresonanztomographie (MRT) erbrachte bei allen 5 Patienten durch den Nachweis eines ausgeprägten Diskusprolapes, zusätzlich bei 2 Patienten durch die Darstellung eines intramyelären Hämatoms and bei 1 Patienten durch das Auftreten eines Rückenmark(RM)-Ödems, indirekte Hinweise auf ein dorsal instabiles Bewegungssegment.
    Notes: Abstract Five patients with hyperextension injuries and dorsally instable motion segments are presented. In the diagnosis of posterior instabilities plain roentgenograms demonstrated no characteristic signs of an injured cervical spine. Flexion and extension views detected a mild degree (2 mm) of retrospondylolisthesis in four cases and a widened disc space in one case. In all five patients the MR findings that made use suspect a posterior unstable motion segment were disc protrusions; in addition, in two patients these was hemorrhage in the spinal cord and in one patient cord edema.
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  • 186
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    Langenbeck's archives of surgery 380 (1995), S. 203-206 
    ISSN: 1435-2451
    Keywords: Magnetic resonance imaging ; Cervical spine ; Titanium implant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Vorstellung von 10 Patienten, von denen sich 8 Rückenmarkschädigungen und 2 radikuläre Beeinträchtigungen im Rahmen von Dislokationsverletzungen der HWS zuzogen und die nach Stabilisierungsoperationen im Zeitraum von 2 Tagen bis 8 Monaten mittels MRT abgekldrt werden, verfolgt das Ziel, die Einsatz-und Aussagembglichkeiten dieser nicht-invasiven Methode darzustellen. Bei 2 Patienten mit schwerem Schädelhirntrauma konnte die Ursache für die Querschnittsläsion eindeutig einer Rückenmarkschädigung zugeordnet werden. Ebenso korrelierten schwere Binnenschäden des Rückenmarks, wie intramyeläre Hämatome oder Transsektionen, mit kompletten Querschnittsläsionen. Alleinige Rückenmarködeme traten mit einer inkompletten Querschnittsläsion auf. Die Beurteilung des Ruckenmarks nach postoperativer neurologischer Verschlechterung ermöglicht den Ausschluß einer Rückenmarkkompression als Ursache. Die MRT eignet sich auch zur lebenslangen Beurteilung von Rückenmark- und HWS-Veränderungen. Somit kann das Rückenmark mit der postoperativen MRT in Problemfällen und zur Prognoseerstellung herangezogen werden.
    Notes: Abstract We present the cases of ten patients who underwent postoperative magnetic resonance assessment after dislocation injuries of the cervical spine and treatment with anterior interbody fusion and titanium implants. Eight patients had spinal cord injuries and two had nerve root disorders. In two patients who had intracranial haematomas and dislocation fractures of the cervical spine, MRI proved useful for identification of parenchymal spinal cord injuries as the reason for transverse lesions. Severe MR findings of the parenchymal spinal cord injuries (haematoma or transection) correlated with complete transverse lesions (4 patients) and oedema of the spinal cord, with incomplete transverse lesions (3 patients). MR enables us to examine the spinal cord after operations to ensure that correct spinal cord decompression has been achieved (3 patients). MRI is useful for detecting disc protrusion or chronic spinal stenosis in patients with titanium implants. All in all, MRI is an important modality in the evaluation of the posttraumatic cervical spine.
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  • 187
    ISSN: 1432-0533
    Keywords: Pes cavus ; Magnetic resonance imaging ; Pathology ; Morphometry ; Peroneus longus hypertrophy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Enlargement of the peroneus longus muscle is a common occurrence in patients with forefoot pes cavus, and may contribute to the cavus deformity. The present study compares the morphology of up to five lower leg muscles from 17 patients with forefoot pes cavus with those of normal muscles. Eight cases had an identifiable neurogenic cause for the cavus. In four cases of hereditary motor-sensory neuropathy, the tibialis anterior showed more severe damage than the peroneus longus. In two cases of cerebral palsy, fibre atrophy and increased oxidative enzyme activity were observed. In nine clinically idiopathic cases, the histological appearances ranged from normal to generalised fibre atrophy or hypertrophy in individual muscles. There was a trend for the mean fibre area to be greater in peroneus longus than in tibialis anterior in six of the idiopathic group of patients. The muscle cross-sectional area on magnetic resonance imaging was correlated closely with the mean fibre area measured on tissue sections. In idiopathic forefoot pes cavus, fibre hypertrophy in peroneus longus (relative to tibialis anterior) may contribute to the cavus deformity. Muscle fibre hyperplasia may contribute to the peroneal muscle enlargement in Friedreich's ataxia. In none of the cases was peroneus longus enlargement due to fat or fibrous tissue replacement.
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  • 188
    ISSN: 1432-0584
    Keywords: Myelodysplasic syndrome ; Leukemia ; Magnetic resonance imaging ; Bone marrow biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 47-year-old male patient with myelodysplasia showed increasing values of serum lactate dehydrogenase (up to 3500 units/l) and an increasing blast count. Several biopsies (taken from the posterior iliac crest) revealed marked hypocellularity. In contrast, magnetic resonance imaging of the marrow demonstrated an inhomogeneous distribution of marrow with hypocellular and also large hypercellular areas not detected by cytological and histological analysis. A location for biopsy of hypercellular marrow was provided by T1-weighted and water-selective magnetic resonance imaging. The findings in the patient were compared with those in a matched healthy volunteer.
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  • 189
    ISSN: 1432-0584
    Keywords: Key words Myelodysplasic syndrome ; Leukemia ; Magnetic resonance imaging ; Bone marrow biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A 47-year-old male patient with myelodysplasia showed increasing values of serum lactate dehydrogenase (up to 3500 units/l) and an increasing blast count. Several biopsies (taken from the posterior iliac crest) revealed marked hypocellularity. In contrast, magnetic resonance imaging of the marrow demonstrated an inhomogeneous distribution of marrow with hypocellular and also large hypercellular areas not detected by cytological and histological analysis. A location for biopsy of hypercellular marrow was provided by T1-weighted and water-selective magnetic resonance imaging. The findings in the patient were compared with those in a matched healthy volunteer.
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  • 190
    ISSN: 1432-0533
    Keywords: Key words Pes cavus ; Magnetic resonance imaging ; Pathology ; Morphometry ; Peroneus longus hypertrophy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Enlargement of the peroneus longus muscle is a common occurrence in patients with forefoot pes cavus, and may contribute to the cavus deformity. The present study compares the morphology of up to five lower leg muscles from 17 patients with forefoot pes cavus with those of normal muscles. Eight cases had an identifiable neurogenic cause for the cavus. In four cases of hereditary motor-sensory neuropathy, the tibialis anterior showed more severe damage than the peroneus longus. In two cases of cerebral palsy, fibre atrophy and increased oxidative enzyme activity were observed. In nine clinically idiopathic cases, the histological appearances ranged from normal to generalised fibre atrophy or hypertrophy in individual muscles. There was a trend for the mean fibre area to be greater in peroneus longus than in tibialis anterior in six of the idiopathic group of patients. The muscle cross-sectional area on magnetic resonance imaging was correlated closely with the mean fibre area measured on tissue sections. In idiopathic forefoot pes cavus, fibre hypertrophy in peroneus longus (relative to tibialis anterior) may contribute to the cavus deformity. Muscle fibre hyperplasia may contribute to the peroneal muscle enlargement in Friedreich's ataxia. In none of the cases was peroneus longus enlargement due to fat or fibrous tissue replacement.
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  • 191
    ISSN: 1433-7347
    Keywords: Hill-Sachs lesion ; Magnetic resonance imaging ; Arthroscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Sports Science
    Notes: Abstract A double-blind prospective study was done with 15 patients with anterior shoulder instability to determine the diagnostic efficacy of magnetic resonance (MR) imaging versus arthroscopy in the evaluation of chondral or osteochondral lesions of the humeral head. MR produced 6 true positives, 5 true negatives and 4 false negatives, and its accuracy and sensitivity were 60% and 87%, respectively, whereas arthroscopy gave 8 true positives, 5 true negatives and 2 false negatives, with a sensitivity of 80% and an accuracy of 87%. All lesions diagnosed with either method were regarded as positive by definition, with the result that the specificity was always 100%. The differences in diagnosis sprang from the false negatives. The 40% discrepancy between the two methods was probbly due to our distinction in MR between intra- and extraarticular osteochondral lesions. In the first group (the 4 MR false negatives), there were three instances of firstdegree intra-articular lesion and one diagnostic error (third-degree lesion). In the second (the 2 arthroscopy false negatives), the lesions were of the extra-articular type. It is thus advisable to employ both of these methods to ensure the correct diagnosis of a Hill-Sachs lesion, and hence the correct choice of treatment.
    Type of Medium: Electronic Resource
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  • 192
    ISSN: 1573-2622
    Keywords: Cerebral dyschromatopsia ; Color pattern visual evoked cortical potentials ; Color vision ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined a 74-year-old man because of difficulty seeing green and the presence of prosopagnosia. His visual acuity was 0.8 in both eyes. He was not congenitally color blind, and there was no family history of color blindness. A left superior homonymous quadrantanopsia was found. The dyschromatopsia was identical in both eyes. The patient showed red-green deficiency on testing with Ishihara plates a deutan defect with Tokyo Medical College plates, strong blue-yellow defects and medium red-green defects with Standard Pseudochromatic Plates II and a tritan defect with the Panel D-15. He failed the New Color separation test with scores of 160 and could not carry out the Farnsworth-Munsell 100-hue test, but his color naming test results were normal. Visual evoked cortical potentials to black-and-white checkerboard and color pattern reversal (Red and Blue-Green, Green and Red-Purple, Purple and Yellow-Green: isochromatic paired checks) stimuli were normal. Bilateral inferior occipital lesions were found by computed tomography and T2-weighted magnetic resonance imaging. Our findings suggested that luminance and color channels up to area 17 in our patient were intact. We believe that our patient's acquired cerebral dyschromatopsia is rare.
    Type of Medium: Electronic Resource
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  • 193
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 23 (1995), S. 637-665 
    ISSN: 1573-9686
    Keywords: Image enhancement ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract We present two applications of wavelet and related techniques to problems arising in medical imaging. Both make considerable use of the edge detection and classification properties of wavelet-type representations. First we describe simple and effective techniques for image denoising and contrast enhancement based on the multiscale edge representation of images. These techniques are sufficiently flexible to successfully address the varying requirements posed by several different medical imaging modalities in common use today. Experimental results are presented to illustrate the application of these techniques to various types of medical images. Next we describe adapted waveform encoding, a technique for magnetic resonance imaging. One advantage of this technique istthat it can be used to efficiently encode edge features of the object being imaged. This has a particular diagnostic application in tracking heart wall thickness during the cardiac cycle, which we present along with some experimental results along this line. We also present an analysis of the signal-to-noise ratios of images formed with this technique, as this is a factor of paramount importance in MRI. The fact that wavelet schemes tend to concentrate energy near edge features makes the result rather different than that found in standard Fourier based approaches. We indicate an exciting potential application of our technique: reducing spectral leakage in phosphorus spectroscopy.
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  • 194
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 242 (1995), S. 278-288 
    ISSN: 0003-276X
    Keywords: Human jaw muscle ; Muscle insertions ; 3D movements ; Jaw tracking ; Magnetic resonance imaging ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Background: The craniomandibular muscles control jaw position and forces at the teeth and temporomandibular joints, but little is known regarding their biomechanical behaviour during dynamic function. The objective of this study was to determine how jaw muscle insertions alter position during different jaw movements in living subjects.Methods: Computer 3D reconstruction of MR images and jaw-tracking were combined to permit the examination of movement with six degrees of freedom. Maximum mandibular opening, protrusive and laterotrusive positions were recorded in four subjects, and the translation and rotation of the putative insertions of masseter, temporal, medial, and lateral pterygoid muscles were measured.Results: The sizes and shapes of regional attachments varied markedly among subjects, and their displacement patterns were different in specific muscles. For instance, when the jaw closed to the dental intercuspal position from maximum gape, the region near the superior insertion site of the masseter moved backward and upward, whereas the region near the inferior insertion site displaced mainly forward. In three subjects, the jaw's rotational center during this act was ∼26-34 mm below the mandibular condyles.Conclusions: Since the movements of each muscle part differ according to variations in the size and shape of insertion areas, individual musculoskeletal form, and patterns of jaw motion during function, the prediction of motion-related muscle mechanics in any one subject is unlikely to be possible without direct measurement of the motion of visualized muscle parts. The present study shows that this information can be obtained. © 1995 Wiley-Liss. Inc.
    Additional Material: 9 Ill.
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  • 195
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 242 (1995), S. 132-135 
    ISSN: 0003-276X
    Keywords: Magnetic resonance imaging ; MR microscopy ; Hamster ; Olfactory bulb ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Background: Magnetic Resonance Imaging (MRI) has been widely used as a noninvasive diagnostic tool for obtaining morphological, metabolic, and functional information from tissue. However, its potential application in observing detailed structure comparable to that of the light microscope has not yet been fully explored. In order to evaluate the usefulness of MR microscopy, a high resolution three-dimensional (3-D) technique was applied to observe the laminar structure of the mammalian olfactory bulb (OB).Methods: Adult male hamsters (Mesocrecitus auratus) were used as an animal model. Hamster OB and the attached anterior olfactory nucleus were removed from the skull for the MRI examinations. The images were performed with a Bruker AMX-400 system equipped with microimaging accessories. T2 weighted 3-D spin echo sequence was used with a field of view of 9 mm and data matrix of 128*128*128. The in-plane resolution was 70*70*70 μm. Histological preparation, including vibratome sectioning at 40 μm and Nissl staining, were used for light microscopic evaluations and comparisons.Results: Five distinct layers from the superficial to the center of the OB were distinguished in the MR images of coronal, sagittal and horizontal slices. As compared to the histological sections at the corresponding cutting planes, the laminar structure of the OB displayed in the MR microscopic images correlated well with its counterparts.Conclusions: MR microscopy is capable of detecting cellular variation of unsectioned and unstained tissue. It can also be easily applied to obtain spatial information with good resolution. It appears to provide a great potential for diagnostic pathology. © 1995 Wiley-Liss, Inc.
    Additional Material: 3 Ill.
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  • 196
    ISSN: 1439-6327
    Keywords: Brain ; Altitude ; Hypoxia ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of the present study was to look for anatomical changes in climbers' brains, using magnetic resonance imaging (MRI), after extremely high-altitude climbs and to relate them to possible associated risk factors. Clinical history, neurological examinations and MRI were carried out on a group of nine climbers before and after climbing to over 7500 m without the use of supplementary oxygen. None of the subjects showed any neurological dysfunctions. In five climbers MRI abnormalities (high signal areas, cortical atrophy) were observed before the expedition. After the descent, two of them showed new high intensity signal areas recorded by MRI. Both subjects suffered severe neurological symptoms during the climb. The present study suggested that the brain changes observed by MRI could be related to the severity of clinical events at high altitude. However, we do not know the exact meaning of such MRI findings or the reason for their location, predominantly in posterior regions of the brain. The new evidence that a high percentage of climbers show MRI brain abnormalities, and especially the appearance of changes after the ascent, reinforces the possibility of a potential neurological risk in high-altitude climbing.
    Type of Medium: Electronic Resource
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