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  • 1985-1989  (2,642)
  • 1965-1969  (87)
  • Engineering General  (2,505)
  • Cat
  • 1
    ISSN: 1432-0568
    Keywords: Lateral reticular nucleus ; Cerebellar nuclei ; Retrograde transport of WGA-HRP ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cerebellar nuclear projection from the lateral reticular nucleus (NRL) was studied in 29 cats by means of retrograde axonal transport after implantation of the crystalline wheat germ agglutinin-horseradish peroxidase (WGA-HRP) complex in the cerebellar nuclei. It was confirmed that all the cerebellar nuclei receive afferent fibres from the NRL with the strongest termination in the ipsilateral interposed nuclei. In addition, these experiments give evidence of a previously unrecognized topical pattern in the projection to the interposed nuclei, arranged according to the same principle as in the projection to the immediately overlying cerebellar cortex. Thus, the anterior interposed nucleus receives fibres from all parts of the main NRL, its rostral part especially from laterally situated neurons, while subsequent more caudal parts from more medially situated neurons, while the posterior interposed nucleus receives fibres mainly from the dorsomedial part of the main NRL. The cerebellar nuclear projection to the NRL was investigated in 15 cats using retrograde transport after ventral microiontophoretical ejections of the WGA-HRP complex in the main NRL. The contralateral rostral fastigial nucleus was confirmed as the main origin of this projection, but projecting neurons were, in addition, discovered rostrally in the anterior interposed and dentate nuclei on the same side. No topical differences could be observed following ejections in different parts of the NRL; the majority of the projecting neurons were always concentrated along the ventral and lateral borders of the fastigial nucleus and in the adjacent medial part of the anterior interposed nucleus.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 79 (1989), S. 330-332 
    ISSN: 1432-0533
    Keywords: Sphingomyelinosis ; Neuropathology ; Histochemistry ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This report presents the clinical, morphological and biochemical findings on an 11-month-old female Siamese cat with neurovisceral sphingomyelinosis. Gross pathological features and histochemical findings are compared with the human disease counterpart and the previously described animal models. Hepatomegaly was observed while splenomegaly was not. Although sphingomyelin in liver and spleen was biochemically elevated, histochemical results in this case were slightly different from those previously recorded in human and feline Niemann-Pick disease. These results suggest that this feline case might be a different type of animal Niemann-Pick disease to that reported previously.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 76 (1989), S. 182-186 
    ISSN: 1432-1106
    Keywords: Retinal ganglion cells ; Orientation bias ; Receptive field centre ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary For cat retinal ganglion cells whose receptive field centres were distributed in specified sections of the left visual field, the deviations of the major axis from the radial, horizontal, and circumferential directions were determined. The percentage of cells with deviations within ± 20° from the radial, horizontal, and circumferential directions were, respectively, 33%, 68%, 16%. In addition, comparison between values of deviation from the horizontal direction for cells located at eccentricities of 10° and 20° from the area centralis showed a statistically significant trend: the bias for the horizontal increased with eccentricity.
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  • 4
    ISSN: 1432-1106
    Keywords: Somatosensory cortex ; Directional sensitivity ; GABA inhibition ; Picrotoxin ; Bicuculline ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The role of intracortical inhibitory processes in the formation of neuronal receptive fields in the vibrissal projection zone of the somatosensory cortex was studied. Iontophoretic application of picrotoxin and bicuculline blocks the inhibition and causes the loss of directional sensitivity in neurons. Activation of inhibition by distant glutamate application gives opposite results — neurons become direction sensitive. A dependence was found between spatial location of activated cells and the pattern of changes of their detector properties. Inhibitory processes caused by natural afferent stimulation lead to similar changes in the functional properties of neurons.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 78 (1989), S. 203-213 
    ISSN: 1432-1106
    Keywords: Corpus callosum ; Development ; Vision ; Dark rearing ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary It is now well established that during normal postnatal development there is a partial elimination of the callosal projections of cortical areas 17 and 18 in the cat and that visual experience early in life can modulate this process. In the present experiments, we quantitatively studied the influence of light, per se, by rearing cats in total darkness. Dark rearing exaggerates the normally occurring partial elimination of immature callosal projections: it causes a significant reduction in the total number of neurons in both the supra-and infragranular layers that send an axon through the corpus callosum and slightly narrows the distribution of these neurons across areas 17 and 18. These data demonstrate that visual stimulation is not necessary either to initiate the partial elimination of immature callosal projections or to stabilize a large fraction of the callosal projections present at birth. However, normal visual stimulation is necessary for the stabilization of the normal complement of callosal projections.
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  • 6
    ISSN: 1432-1106
    Keywords: Control of respiration ; Intercostal muscle afferents ; Phrenic nerve ; Abdominal muscle afferents ; Expiratory neurons ; Abdominal muscle control ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Our objective was to determine if caudal ventral respiratory group (VRG) expiratory (E) neurons that drive abdominal expiratory motoneurons in the lumbar cord respond to intercostal and lumbar nerve afferent stimulation. Results showed that 92% of medullary E-neurons that were antidromically activated from the upper lumbar cord reduced their activity in response to stimulation of external and internal intercostal and lumbar nerve afferents. We conclude that afferent information from intercostal and abdominal muscle tendon organs has an inhibitory effect on caudal VRG E-neurons that drive abdominal expiratory motoneurons.
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  • 7
    ISSN: 1432-1106
    Keywords: Lateral geniculate nucleus ; Optic tract ; Sustained cells ; Transient cells ; Temporal luminance modulation ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We recorded the response of sustained (X) and transient (Y) cells in the cat lateral geniculate nucleus (LGN) and optic tract to a stationary spot while the spot luminance was increased and decreased with a constant rate (linear luminance functions), or modulated sinusoidally. The spot filled the receptive field center, and was surrounded by an annulus of fixed luminance. The LGN X cells seemed to perform a differentiation-like operation in the time domain at slow temporal modulations, giving information about rate of luminance change. To the linear luminance functions the cells responded with a constant firing rate. The on-center cells were activated during increasing luminance, the off-center cells during decreasing luminance. This firing rate increased monotonically with rate of luminance change. To low-frequency sinusoidal modulations the cells had a marked negative phase shift. The response of the LGN Y cells had a transient component shortly after the luminance started to increase (on-center cells) or decrease (off-center cells), followed by a secondary, gradually changing component. The peak of the transient component occurred on average when the response of the X cells increased most rapidly. To low-frequency sinusoidal modulation the average negative phase shift of this peak was twice the average of the X cells. The Y system could accordingly provide information about rate of change in the response of the X system. In the optic tract the X fiber response resembled the LGN X cell response in most respects. The Y fibers had only a weak transient response component, so this component was accentuated in the thalamic relay. Also the sensitivity for rate of luminance change was increased in LGN.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 74 (1989), S. 131-138 
    ISSN: 1432-1106
    Keywords: Phrenic motoneurons ; Intracellular recording ; Interactions ; Recurrent EPSPs ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Intracellular recordings were made from 220 Phrenic Motoneurons (PM) in anaesthetized, spontaneously breathing cats, deafferented from C3 to C7, in order to look for somatic events related to the Recurrent Responses (RR) evoked in PM axons by repetitive stimulation of the phrenic nerve. RR appear sporadically at a constant latency, originate from a spinal nicotinic mechanism and can be evoked in a PM without the presence of an antidromic volley in its axon (Khatib et al. 1986). 2. Using stimuli effective for eliciting RR in axons, we failed to observe intracellularly somatic events corresponding to RR after the occurence of an antidromic action potential. RR were observed extracellularly in two cases, but in both cases the recording originated from axons. 3. We attempted to elicit somatic RR without a preceding antidromic action potential, using either parathreshold stimulation of the impaled PM, or suprathreshold stimulation of a phrenic strand which excluded the axon of the impaled PM. In both cases, RR-like events, with very stable latencies, appeared sporadically in 4/142 and 2/15 PMs respectively. 4. Parathreshold stimuli or stimulation of a strand were coupled with averaging of the synaptic noise in order to look for small events temporally related to the stimuli. Short latency small depolarizations, looking-like recurrent EPSPs, were revealed in 22/142 and 5/15 PMs respectively. 5. These results confirm the existence of interrelations between PMs, providing for re-excitation and coupling within the phrenic pool, in addition to centrally imposed synchronization.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 74 (1989), S. 220-226 
    ISSN: 1432-1106
    Keywords: Cat ; Medial geniculate body ; Hearing ; Tonotopic organization ; Single unit recording
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The tonotopic organization observed in the present study for the pars lateralis (LV) of the medial geniculate body (MGB) in nitrous oxide anesthetized cats is generally consistent with that previously reported under barbiturate anesthesia. The present data, however, provide evidence for local deviations in characteristic frequency (CF) using appropriate sampling procedures of single units. Although the majority of pairs of units recorded simultaneously with the same microelectrode showed comparable CFs, a few pairs of such neighbouring units displayed CF disparities of up to 1.5 octaves. In addition, some units characterized by an elevated threshold had a CF deviating significantly from the general CF progression observed for the majority of units having low thresholds. This study points out the influence of the sampling procedure on the quality of the tonotopic organization observed in the MGB in addition to a possible effect of the level of anesthesia.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 74 (1989), S. 272-278 
    ISSN: 1432-1106
    Keywords: Cat ; Corpus callosum ; Optic chiasm ; Stereoacuity ; Visual acuity ; Visual fields
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied the role of the transcallosal pathway in stereopsis by measuring binocular and monocular depth perception in two cats that had undergone section of the optic chiasm at the age of 21 d. To ensure that the surgery did not impair vision to the extent that depth perception could not be evaluated, visual acuity and visual fields were also measured. In both of the chiasm-sectioned animals the visual fields were reduced and the visual acuity was substantially lower than in normal cats, with a maximum of about 2 cyc deg-1. Binocular depth thresholds of the chiasm-sectioned cats were worse than those of the normal cat but were better than their own monocular thresholds. These results suggest that the chiasm-sectioned animals were still able to use binocular cues to judge depth and indicate that the indirect pathway through the corpus callosum is sufficient to mediate binocular depth perception.
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  • 11
    ISSN: 1432-1106
    Keywords: Cutaneous EPSPs ; Fictive locomotion ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We examined modulation of transmission in short-latency, distal hindlimb cutaneous reflex pathways during fictive locomotion in 19 decerebrate cats. Fictive stepping was produced either by electrical stimulation of the mesencephalic locomotor region (MLR) or by administration of Nialamide and 1-DOPA to acutely spinalized animals. Postsynaptic potentials (PSPs) produced by electrical stimulation of low threshold afferents (〈 2.5 times threshold) in the superficial peroneal (SP), sural, saphenous or medial plantar nerves were recorded intracellularly from various extensor (n = 28) and flexor (n = 24) motoneurons and averaged throughout the step cycle, together with voltage responses to intrasomatic constant current pulses (in order to monitor relative cell input resistance). Each motoneuron studied displayed rhythmic background oscillations in membrane potential and correlated variations in input resistance. The average input resistance of extensor motoneurons was lowest during mid-flexion, when the cells were relatively hyperpolarized and silent. Conversely, average input resistance of flexor motoneurons was highest during mid-flexion, when they were depolarized and active. The amplitude of the minimum-latency excitatory components of PSPs produced by cutaneous nerve stimulation were measured from computer averaged records representing six subdivisions of the fictive step cycle. Oligosynaptic EPSP components were consistently modulated only in the superficial peroneal responses in flexor motoneurons, which exhibited enhanced amplitude during the flexion phase. With the other skin nerves tested (sural, saphenous, and plantar), no consistent patterns of modulation were observed during fictive locomotion. We conclude that transmission through some, but not all, oligosynaptic excitatory cutaneous pathways is enhanced by premotoneuronal mechanisms during the flexion phase of fictive stepping in several cat hindlimb motor nuclei. The present results suggest that the patterns of interaction between the locomotor central pattern generator and excitatory cutaneous reflex pathways depend on the source of afferent input and on the identity of the target motoneuron population.
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 76 (1989), S. 307-314 
    ISSN: 1432-1106
    Keywords: Moving stimuli ; Orientation specificity ; Preferred axes ; Spot-response-axis ; Striate cortex ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The responses of 82 simple cells and 41 complex cells in area 17 of anesthetized and paralysed cats were examined with light bars of different length. For 84% of the simple cells and 66% of the complex cells the preferred axis of orientation of a stationary flashing long bar (orientational selectivity) and the preferred axis of movement of a small spot were parallel. As a consequence, the axis of maximal response to a moving light spot was mostly orthogonal to the optimal axis of a moving bar. Thus, a single cell responds to two perpendicular axes of preferred movement one for a long bar and one for a light spot, respectively. For both axes independent direction preferences could be distinguished. Additional preferred axes of movement between the two orthogonal extremes could be found with moving bars of intermediate lengths. This can be explained by the fact that cells with a pronounced response to a moving spot showed a strong tendency for intermediate bar length to elicit responses consisting of a superposition of both components. Therefore, decreasing bar length resulted in a gradual rotation of the preferred direction of movement from orthogonal to parallel with respect to the orientational axis, rather than to a mere widening of the tuning curve. Accordingly, the change in orientation selectivity with decreasing bar length is a regular transition from the orientation dependent response to a response type that depends only on the movement axis of the spot. Thus, in a simple model, the resulting response characteristic can be interpreted as an average of both components weighted according to the length of the stimulus.
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  • 13
    ISSN: 1432-1106
    Keywords: Motor cortex ; Conditioned movement ; Posture ; Balance control ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The role of the sensorimotor cortex in the postural adjustments associated with conditioned paw lifting movements was investigated in the cat. Cats were trained to stand quietly on four strain gauge equipped platforms and to perform a lift-off movement with one forelimb when a conditioned tone was presented. The parameters recorded were the vertical forces exerted by the paws on each platform, the lateral and antero-posterior displacements of rods implanted on the T2, T12, L5 vertebrae as well as their rotation, and the EMG of triceps and biceps of both forelimbs. Before lesion, the postural adjustment consisted of a “nondiagonal” pattern where the CG was displaced laterally inside the triangle formed by the three remaining supporting limbs. Here a lateral bending of the thoracic column toward the supporting forelimb could be observed. The associated EMG pattern consisted of an early activation of the triceps lateral head in the moving limb which was probably responsible for the body displacement toward the opposite side, and a late biceps activation associated with the lift. In the supporting forelimb, a coactivation of the biceps and triceps was usually present. After contralateral sensorimotor lesion, the conditioned lifting movements were lost for 4–15 days after the lesion, before being subsequently recovered. The same lateral CG displacement and bending of the back was seen after lesion as before, which indicates that the goal of postural adjustment was preserved. However, the means of reaching it were modified. In most of the intact animals, the CG displacement was achieved in one step, whereas in the animals with lesions, the displacement was made either according to a slow ramp mode or in a discontinuous manner involving several steps. The mechanisms responsible for this disturbance are discussed.
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 77 (1989), S. 577-584 
    ISSN: 1432-1106
    Keywords: Motoneuron pool ; Inhibition ; Monosynaptic reflex ; Recruitment level ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The motoneurons to the Soleus muscle in the decerebrate cat were activated by the crossed extensor reflex, elicited by stimulation of the contralateral common peroneal (CP) nerve. Monosynaptic reflexes were obtained from the Soleus motoneuron pool by stimulation of the cut L7-S1 dorsal roots. The amplitude of the reflex increased approximately linearly with the recruitment level of the motoneuron pool. Tonic postsynaptic inhibition was induced in the Soleus moto-neuron pool by repetitive antidromic stimulation of the Lateral Gastrocnemius (LG) and Medial Gastrocnemius (MG) nerves at a rate of 17–47 stimuli/s. This reduced the size of the monosynaptic reflex at rest by at least 40%. However, when the motoneurons were active, the amplitude of the monosynaptic reflex obtained during repetitive stimulation of the LG-MG nerve increased with the recruitment level along the same curve as the control reflexes. Thus, tonic postsynaptic inhibition of the motoneurons per se cannot control the amplitude of the monosynaptic reflex independently of the recruitment level of the motoneuron pool. These experimental results verify predictions from computer simulations and suggest by exclusion that presynaptic inhibition is needed to control the amplitude of the monosynaptic reflex independently of the recruitment level of the motor pool.
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  • 15
    ISSN: 1432-2072
    Keywords: Oro-facial dyskinesia ; Globus pallidus ; GABA ; Acetylcholine ; Behaviour ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The possible role of cholinergic mechanisms in the sub-commissural part of the globus pallidus (scGP) in the induction of oro-facial dyskinesia (OFD) was studied in cats. Local injections of the cholinergic agonist carbachol into the scGP elicited tongue protrusions in a dose dependent way (100–1000 ng/0.5 μl). The effect elicited by 1000 ng carbachol was selectively antagonized by the cholinergic antagonist scopolamine (10 μg/0.5 μl); this dose of scopolamine was ineffective when injected alone. The tongue protrusions resulted from both normal and abnormal movements: whereas normal movements simply consisted of protruding the flat tongue, abnormal movements implied a variety of movements, especially curling upwards the lateral side(s) or tip of the tongue inside or outside the oral cavity. The abnormal carbachol-induced tongue protrusions formed part of a syndrome marked by dyskinetic movements of the muscles of the eye, ear and cheek, and were identical to those seen previously after local injections of picrotoxin (250–500 ng). Intra-pallidal injections of the abovementioned dose of scopolamine had no effect on the tongue protrusions induced by local injections of 375 ng picrotoxin. However, local injections of 100 ng muscimol, which was previously found to attenuate significantly the effect of 375 ng picrotoxin and which was ineffective when injected alone, significantly attenuated the tongue protrusions induced by local injections of 1000 ng carbachol. These data suggest that the cholinergic effects are mediated via a GABAergic mechanism, but not vice versa. The results are discussed in view of GABAergic and anticholinergic therapies used in oro-facial dyskinesia.
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 414 (1989), S. 235-244 
    ISSN: 1432-2013
    Keywords: Cat ; Urinary bladder ; Parasympathetic ganglion neurone ; Postganglionic stimulation ; Synaptic potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intracellular recording techniques were used to examine and compare synaptic potentials evoked by stimulating pre- and postganglionic nerve trunks in cat bladder parasympathetic ganglia. In the 76 ganglion cells exammed, two types of responses were recorded on stimulating the postganglionic nerve: an antidromic action potential (type Post NS1;n=30) or a fast excitatory postsynaptic potential (f-EPSP; type PostNS2;n=46) which resulted in an orthodromic-like action potential. In some of the cells exhibiting a PostNS1 response (n=19), a fast depolarization was superimposed on the antidromic spike. This depolarization was due to the synaptic activation of nicotinic receptors. In many of the cells exhibiting either PostNS1 or PostNS2 responses, repetitive stimulation of the postganglionic nerve induced a slow hyperpolarization. Applying nicotinic (hexamethonium, methonium, 0.5–1 mM), muscarinic (atropine, 1 μM), alpha-adrenergic (phentolamine, 1 μM) and purinergic (caffeine, 0.5–1 mM) receptor antagonists completely inhibited the tetanus-induced slow hyperpolarization in some cells (n=5). In other cells (n=15), a slow hyperpolarization persisted in the presence of these antagonists. These results indicate that stimulation of the postganglionic nerve trunk of cat bladder parasympathetic ganglia can elicit not only an antidromic action potential, but also synaptic potentials which are mediated by the activation of cholinergic (nicotinic and muscarinic), noradrenergic and purinergic receptors, as well as a non-cholinergic, non-alpha-adrenergic and non-purinergic synaptic potential.
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  • 17
    ISSN: 1432-1912
    Keywords: 5-HT3 receptors ; Radioligand binding ; [3H]ICS 205-930 ; Cat ; Rabbit ; Vagus nerve ; Superior cervical ganglion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The binding characteristics of [3H]ICS 205-930, a 5-hydroxytryptamine 5-HT3 receptor antagonist, were investigated in membranes prepared from cat and rabbit vagus nerve (VN) and superior cervical ganglion (SCG). The autoradiographic localisation of 5-HT3 recognition sites was also assessed using [3H]ICS 205-930 in slices from cat medulla oblongata, nodose ganglion and vagus nerve. [3H]ICS 205-930 bound to a homogeneous population of high affinity recognition sites in cat VN: Bmax = 201 ± 43 fmol/mg protein, pKD = 9.26 ± 0.17 and SCG: Bmax = 291 ± 40 fmol/mg, pKD = 9.35 ± 0.80 (n = 3). Competition experiments performed in membranes from cat VN and SCG with agonists and antagonists suggested the presence of a homogeneous population of [3H]ICS 205-930 recognition sites. Competition curves were steep and monophasic and were best fitted by a 1 receptor site model. The following rank order of affinity for [3H]ICS 205-930 binding sites was observed with antagonists: SDZ 206-830 = ICS 205-930 〉 BRL 43694 〉 SDZ 206–792 〉 quipazine 〉 MDL 72222 〉 metoclopramide 〉 mCPP and agonists: 2-methyl-5-HT = 5-HT 〉 phenylbiguanide. A similar profile was observed for a limited series of compounds in rabbit membranes. Drugs acting at 5-HT1, 5-HT2 and dopamine receptors (domperidone, spiperone and metergoline) showed very low affinities for [3H]ICS 205-930 recognition sites. The sites labelled with [3H]ICS 205-930 in vagus nerve and superior cervical ganglion of both species displayed the pharmacological profile of a 5-HT3 receptor. There was a significant correlation between the rank order of affinity of the tested compounds for [3H]ICS 205-930 recognition sites in cat and rabbit membranes and their rank order of affinity for 5-HT3 receptors from neuroblastoma-glioma NG 108-15 cells. Autoradiographic studies suggest that [3H]ICS 205-930 binding sites are present over and around the nodose ganglion cell somata, along certain fibers of the vagus nerve and in the terminal areas of this nerve in the medullar nucleus of the vagus. The present data demonstrate that [3H]ICS 205-930 identifies 5-HT3 receptors in preparations of cat and rabbit vagus nerve and superior cervical ganglion.
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  • 18
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    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 340 (1989), S. 764-766 
    ISSN: 1432-1912
    Keywords: Nucleus of the solitary tract (NTS) ; GABA release ; Carotid occlusion ; Blood pressure ; Push-pull cannula ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized cats, the nucleus of the solitary tract was bilaterally superfused through push-pull cannulae with artificial cerebrospinal fluid (CSF) and the effect of carotid occlusion on the release of endogenous GABA was investigated. Bilateral carotid occlusion led to a rise in blood pressure which was associated with a very pronounced increase in the release rate of GABA in the nucleus of the solitary tract. The results demonstrate the hypertensive function of GABA in the nucleus of the solitary tract and the importance of GABAergic neurons of this nucleus for the central cardiovascular control.
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  • 19
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    Springer
    Experimental brain research 75 (1989), S. 639-643 
    ISSN: 1432-1106
    Keywords: Motor cortex ; Somaesthetic responses ; Spinothalamic system ; Intracellular recording ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Evidence is presented that in the cat, the spinothalamic system contributes to short latency somaesthetic responses in motor cortex efferent cells. Intracellular recordings performed on identified pyramidal tract cells and corticospinal cells show that these cells are still activated and/or inhibited from the periphery after a set of central nervous lesions leaving intact only the ventral half of the spinal cord. The responses were attributed to the spinothalamic system. The ascending system is activated through collaterals of afferent fibres running in the dorsal columns of the spinal cord. This peripheral link to the motor cortex might participate in updating the motor command on the basis of information feedback from the periphery.
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  • 20
    ISSN: 1432-1106
    Keywords: Precerebellar nuclei ; Cerebellar cortex and nuclei ; Fluoro-Gold ; Rhodamine-B-isothiocyanate (RITC) ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The projections from certain brain stem precerebellar nuclei to the cerebellar cortex and nuclei have been examined in the cat by using the retrograde fluorescent double-labelling technique. Crystalline Fluoro-Gold was implanted into the left cerebellar nuclei from the contralateral side and rhodamine-B-isothiocyanate was injected into the overlying cerebellar cortex. The inferior olive, the lateral reticular nucleus, and the reticular tegmental pontine nucleus all contained double- as well as single-labelled neurons, and it was concluded that these nuclei have a high number of neurons whose axons branch to both the cerebellar cortex and nuclei. The neurons in the paramedian reticular nucleus and the pontine nuclei proper appear to project only to the cerebellar cortex.
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  • 21
    Electronic Resource
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    Springer
    Experimental brain research 78 (1989), S. 374-379 
    ISSN: 1432-1106
    Keywords: Thermosensitivity ; Spinal cord ; Ascending pathways ; Behaviour ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The behavioural thermosensitivity of six cats was measured before and after single stage, symmetrical, bilateral, surgical lesions of the cervical spinal cord. The lesions were aimed at an area in the most ventral parts of the dorsal halves of the lateral funiculi. Unilateral lesions of that area have previously been found to cause reproducible, although subtotal, contralateral thermosensory defects, which were attributed to interruption of the thermosensory spinothalamic pathway. The lesions of three of the present cats were found to be incomplete, and those animals showed no postoperative thermosensory deficiency. Two of the cats with complete lesions showed marked post-operative defects, especially immediately after the operations, but the third cat with a complete lesion showed no postoperative thermosensory defect at all. The differences between the last three animals have been compared to the irregularity of previous reports about thermosensitivity after spinal cord lesions in man and animals, and may depend on the testing technique, rather than differences of thermosensitivity per se.
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  • 22
    ISSN: 1432-1106
    Keywords: Bicuculline ; Inhibition ; Latency ; Receptive field profile ; Somatosensory cortex ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In cortical area 3b of cats, responses of 76 single neurons to punctate indentations were recorded before and during iontophoretic administration of bicuculline methiodide (BMI), a GABAergic antagonist, at levels that did not affect spontaneous activity. Constant amplitude indentations were applied to selected sites along distalproximal and radial-ulnar axes that intersected the most sensitive area in the receptive field. Profiles of response magnitudes were used to measure receptive field dimensions before and during antagonism of GABAergic inhibition. Blockade of GABAergic transmission caused receptive field dimensions of 48 rapidly-adapting neurons to increase an average 141%, or nearly 2.5 times their original size. Analysis of the spatial distribution of inhibition indicated that in-field inhibition was larger than surround inhibition. During BMI administration, response latency was significantly longer for response elicited from the expanded territory than for responses elicited from within the original receptive field, suggesting that receptive field expansion might be mediated by multisynaptic intracortical connections. The magnitude of receptive field expansion was independent of receptive field size or peripheral location. In a substantial number of neurons, however, BMI produced asymmetric expansions that extended only in the proximal direction. For 9 slowly-adapting neurons, BMI produced measureable increases in receptive field dimensions, but these changes were significantly smaller than the changes in rapidly-adapting neurons.
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  • 23
    ISSN: 1432-1106
    Keywords: NMDA receptor ; Visual cortex ; Excitatory amino acid ; Slice ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Actions of excitatory amino acid (EAA) antagonists on the responses of cells in layers II/III and IV of the cat's visual cortex to stimulation of layer VI and the underlying white matter were studied in slice preparations. Antagonists used were 2-amino-5-phosphonovalerate (APV), a selective antagonist for the N-methyl-D-aspartate (NMDA) type of EAA receptors, and kynurenate, a broadspectrum antagonist for the three types of EAA receptors. In extracellular recordings it was demonstrated that most of the layer II/III cells were sensitive to APV, while the great majority of the layer IV cells were not, By contrast, kynurenate suppressed the responses completely in both layers. Excitatory post-synaptic potentials (EPSPs) evoked by stimulation of layer VI and the while matter were recorded intracellularly from layer II/III neurons. To determine whether the EPSPs were elicited mono- or polysynaptically, the synaptic delay for each EPSP was calculated from a pair of onset latencies of EPSPs evoked by stimulation of the two sites. Forty-two percent of the layer II/III cells were classified as having monosynaptic EPSPs. In 60% of these monosynaptic cells, the rising slope of the EPSPs was reduced by APV while in the other 40%, it was not. In the former (APV-sensitive cells), subtraction of the APV-sensitive component from the total EPSP indicated that the onset latency of the NMDA receptor-mediated component was roughly equal to that of the non-NMDA component. In the latter (APV-resistant cells), only the slowly-decaying component was in part mediated by NMDA receptors. The conduction velocities of the afferent fibers innervating APV-resistant cells were slower than those of the APV-sensitive cells, suggesting that both types of cells are innervated by different types of afferents. The polysynaptic EPSPs of almost all layer II/III cells were sensitive to APV. The subtraction method indicated that the NMDA component had about the same magnitude as the non-NMDA components. When the slices were superfused by a Mg2+-free solution, the EPSPs were potentiated dramatically, but this potentiation was reduced to the control level during the administration of APV. Similarly, APV-sensitive components were potentiated during the administration of bicuculline, a selective antagonist for gamma-aminobutyric acid receptors of A type. These results suggest that NMDA receptors participate, at varying degrees, in excitatory synaptic transmission at most layer II/III cells in the cat's visual cortex, and their actions appear to be regulated by intracortical inhibition.
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  • 24
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    Experimental brain research 77 (1989), S. 94-102 
    ISSN: 1432-1106
    Keywords: Eye movement ; Brainstem ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study maps the eye movements evoked by microstimulations in the medulla of 9 alert cats. Trains of square waves (20 μA amplitude, 0.2 msec duration, 200 Hz) were delivered through glass-covered tungsten microelectrodes (0.5–1 MΩ). Movements of both eyes were recorded by the magnetic field/eye coil technique. Stimulation of the prepositus hypoglossi nucleus (PH) evoked nystagmus with ipsilaterally-directed slow phases followed by after-nystagmus with contralaterally-directed slow phases. Stimulation of the medial vestibular nucleus (MVN) induced nystagmus whose slow phases were more often ipsilaterally-directed but at time contralaterally-directed. At nearly all sites where we stimulated the reticular formation underlying prepositus and vestibular nuclei (from P4.5 to P12), we recorded versional conjugate movements. They were most often ipsilaterally-directed. Some microstimulations in the region of the medial longitudinal fasciculus evoked recentering eye movements: regardless of the initial position of the gaze (to the left as well as to the right), microstimulations given at the same place induced a movement of both eyes toward their neutral position. The amplitude of this movement was proportional to the eccentricity of the pre-stimulation position of the gaze.
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  • 25
    ISSN: 1432-1106
    Keywords: Pharyngeal vagus nerve ; Pharyngeal glossopharyngeal nerve ; Nucleus ambiguus ; Retrofacial nucleus ; Lateral reticular formation ; Nucleus of solitary tract ; Alaminar spinal trigeminal nucleus ; Horseradish peroxidase ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The central distributions of efferent and afferent components of the pharyngeal branches of the vagus (PH-X) and glossopharyngeal (PH-IX) nerves in the cat were studied by soaking their central cut ends in a horseradish peroxidase (HRP) solution. HRP-labelled PH-X neurones were distributed ipsilaterally in the rostral part of the nucleus ambiguus (NA) and the retrofacial nucleus (RFN); HRP-labelled PH-IX neurones were found in the ipsilateral RFN and the bulbopontine lateral reticular formation (RF). Vagal pharyngeal neurones constituted a large population of brainstem motoneurones. The population of HRP-labelled glossopharyngeal neurones was divided into two components. Indeed, on the basis of their location and somal morphology, the most ventral cells were identified as cranial motoneurones and those scattered in the lateral RF as parasympathetic preganglionic neurones. Application of HRP to the PH-IX nerve resulted also in the labelling of fibres and terminals in the alaminar spinal trigeminal nucleus and the nucleus of the solitary tract (NTS). The afferent fibres entered the lateral medulla with the glossopharyngeal roots, ran dorsomedially, then turned caudally toward the NTS and the caudal part of the alaminar spinal trigeminal motor (V) nucleus. In the NTS, labelled fibres ran mainly along the solitary tract, projecting to terminals in the dorsal and dorsolateral nuclei of the NTS.
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  • 26
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    Experimental brain research 78 (1989), S. 336-344 
    ISSN: 1432-1106
    Keywords: Vagal pharyngeal nerve ; Glossopharyngeal nerve ; Single fibre recordings ; Respiratory-related units ; Superior laryngeal nerve ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In decerebrate, paralyzed and artificially ventilated cats, we recorded the discharge of 64 motor axons supplying the pharyngeal muscles. Filaments containing motor axons, with discharges related to the respiratory cycle (phrenic nerve activity), were teased from the pharyngeal branches of the vagus and glossopharyngeal nerves. Most units (n = 41) fired only during expiration and exhibited a steady, a decreasing or a late augmenting discharge pattern. These units were found only in vagal filaments. Twenty three units discharged during inspiration and exhibited a steady, a late augmenting or a tonic discharge pattern. The inspiratory-related units were present in both the vagus (n=13) and glossopharyngeal (n=10) nerves. Nineteen of 20 pharyngeal inspiratoryrelated units tested were activated at short latency (range 3.4 to 8.0 ms) by stimulation of afferents in the superior laryngeal nerve (SLN). In 13 of these, such stimulation also suppressed their spontaneous activity. SLN stimulation elicited in all 17 pharyngeal expiratory-related units tested a short latency (range 0 to 8 ms) reduction of activity, followed in 7 units by an increase in activity. SLN stimulation occasionally evoked single or rhythmic multifibre bursts in the vagal pharyngeal filaments. These bursts, involving expiratory-related units, likely correspond to the buccopharyngeal stage of swallowing.
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  • 27
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    Experimental brain research 78 (1989), S. 501-513 
    ISSN: 1432-1106
    Keywords: Somatosensory cortex ; Interlaminar ; Corticortical ; SI ; Area 3b ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The morphology of single neurons in area 3b of cat primary somatosensory (SI) cortex was examined after horseradish peroxidase (HRP) injections. Neurons were labeled either by intracellular injection of HRP following intracellular recording or by small extracellular iontophoretic HRP injections. Both pyramidal and nonpyramidal neurons were labeled and reconstructed from serial sections. Their axons had local, interlaminar and interareal patterns of termination. Most neurons formed local axonal fields around their cell bodies and dendrites. Pyramidal neurons in cortical layer IV sent axons up into layers II and III, neurons in layers II and III sent axons down to layer V, and layer V neurons sent axons to layer VI as well as back to the upper layers. Layer VI neurons sent axons back to the upper cortical layers in a unique bowl-shaped pattern. The horizontal distribution of axons of pyramidal cells in layer III was extremely widespread. Axons of layer III neurons in area 3b terminated within 3b and area 1, but not in other areas of SI. Layer III neurons in area 1 distributed axon collaterals to all fields of SI as well as projecting a main axon to motor cortex. In general, the axon collaterals of area 3b pyramidal cells outside layer III remained confined to area 3b. Most of the nonpyramidal neurons labeled were basket cells in layers III and VI. These neurons formed dense axonal fields around their cell bodies, and none of their axons could be followed into the underlying white matter. The results of the present study demonstrate that area 3b somatosensory cortical neurons and their axons are vertically organized in a manner similar to that reported for other sensory cortical areas. They also show that widespread horizontal connections are formed by pyramidal neurons of layer III, and that these horizontal axons can travel for great distances in the cortical grey matter.
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  • 28
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    Experimental brain research 77 (1989), S. 271-282 
    ISSN: 1432-1106
    Keywords: Red nucleus ; Motor initiation ; Single-unit activity ; Reaction time ; Delayed movement ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The activity of 98 Red Nucleus neurons was recorded in 3 cats operantly conditioned to perform a ballistic forelimb flexion movement triggered after a brief sound in a simple Reaction Time condition, or Delayed after the same sound in the presence of a tone cue. Fifty-eight task related neurons presented changes of activity in either one or both conditions. Forty-four of them were studied quantitatively and classified in 3 categories: 1) only 16% of the units presented similar changes of firing preceding the triggered or delayed movement; 2) most units (55%) presented different changes of activity in the two conditions: in the Delayed condition, the activation occurred earlier before the movement, and/or the change in magnitude was reduced or the pattern of activity was modified; 3) moreover, for 29% of the units, the change of activity observed before movement in the Reaction Time condition was severely reduced or even absent in the Delayed condition. For some of these neurons a building-up of activity was observed very early in the Reaction Time condition, during the preparatory period, well before the occurrence of the conditioned stimulus. These results show that the Red Nucleus activity preceding a movement is clearly dependent on its initiation conditions. The distinct patterns of unit firing observed in the Reaction Time condition and in the Delayed condition are tentatively related to the different preparation and initiation constraints determined by the behavioral conditions.
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  • 29
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    Experimental brain research 76 (1989), S. 519-529 
    ISSN: 1432-1106
    Keywords: Pontine tegmentum ; Cholinergic neurons ; Single units ; Sleep-waking states ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A total of 260 neurons were recorded in the rostral pontine tegmentum of freely moving cats during the sleep-waking cycle. Of these, 207 neurons (80%) were located in the dorsal pontine tegmentum containing monoaminergic and choline acetyltransferase (ChAT)-immunoreactive, or cholinergic neurons. In addition to presumably monoaminergic PS-off cells (n = 51) showing a cessation of discharge during paradoxical sleep (PS) and presumably cholinergic PGO-on cells (n = 40) exhibiting a burst of discharge just prior to and during ponto-geniculo-occipital (PGO) waves, we observed tonic (n = 108) and phasic (n = 61) neurons exhibiting, respectively, tonic and phasic patterns of discharge during wakefulness and/or paradoxical sleep. Of 87 tonic cells histologically localized in the dorsal pontine tegmentum rich in cholinergic neurons, 46 cells (53%) were identified as giving rise to ascending projections either to the intralaminar thalamic complex (n = 26) or to the ventrolateral posterior hypothalamus (n = 13) or to both (n = 9). Two types of tonic neurons were distinguished: 1) tonic type I neurons (n = 28), showing a tonic pattern and high rates of discharge during both waking and paradoxical sleep as compaired with slow wave sleep; and 2) tonic type II neurons (n = 20), exhibiting a tonic pattern of discharge highly specific to the periods of paradoxical sleep. Tonic type I neurons were further divided into two subclasses on the basis of discharge rates during waking: a) rapid (Type I-R; n = 17); and b) slow (Type I-S; n = 11) units with a discharge frequency of more than 12 spikes/s or less than 5 spikes/s, respectively. Like monoaminergic PS-off and cholinergic PGO-on cells, both tonic type II and type I-S cells were characterized by a long spike duration (median: 3.3 and 3.5 ms), as well as by a slow conduction velocity (median: 1.8 and 1.7 m/s). In the light of these data, we discuss the possible cholinergic nature and functional significance of these ascending tonic neurons in the generation of neocortical electroencephalographic desynchronization occurring during waking and paradoxical sleep.
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  • 30
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    Experimental brain research 75 (1989), S. 265-279 
    ISSN: 1432-1106
    Keywords: Rostral interstitial nucleus of the MLF ; Interstitial nucleus of Cajal ; Spinal cord ; Motoneurons ; Neck muscles ; Axial muscles ; Vertical eye and head movements ; Autoradiography ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Eye and head movements are strongly interconnected, because they both play an important role in accurately determining the direction of the visual field. The rostral brainstem includes two areas which contain neurons that participate in the control of both movement and position of the head and eyes. These regions are the caudal third of Field H of Forel, including the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF) and the interstitial nucleus of Cajal with adjacent reticular formation (INC-RF). Lesions in the caudal Field H of Forel in monkey and man result in vertical gaze paralysis. Head tilt to the opposite side and inability to maintain vertical eye position follow lesions in the INC-RF in cat and monkey. Projections from these areas to extraocular motoneurons has previously been observed. We reported a study of the location of neurons in Field H of Forel and INC-RF that project to spinal cord in cat. The distribution of these fiber projections to the spinal cord are described. The results indicate that: 1. Unlike the neurons projecting to the extra-ocular muscle motoneurons, the major portion of the spinally projecting neurons are not located in the riMLF or INC proper but in adjacent areas, i.e. the ventral and lateral parts of the caudal third of the Field H of Forel and in the INCRF. A few neurons were also found in the nucleus of the posterior commissure and ventrally adjoining reticular formation. 2. Neurons in caudal Field H of Forel project, via the ventral part of the ventral funiculus, to the lateral part of the upper cervical ventral horn. This area includes the laterally located motoneuronal cell groups, innervating cleidomastoid, clavotrapezius and splenius motoneurons. At lower cervical levels labeled fibers are distributed to the medial part of the ventral horn. Projections from the caudal Field H of Forel to thoracic or more caudal spinal levels are sparse. 3. Neurons in the INC-RF, together with a few neurons in the area of the nucleus of the posterior commissure, project bilaterally to the medial part of the upper cervical ventral horn, via the dorsal part of the ventral funiculus. This area includes motoneurons innervating prevertebral flexor muscles and some of the motoneurons of the biventer cervicis and complexus muscles. Further caudally, labeled fibers are distributed to the medial part of the ventral horn (laminae VIII and adjoining VII) similar to the projections of Field H of Forel. A few INC-RF projections were observed to low thoracic and lumbosacral levels. It is argued that the neurons in the caudal Field H of Forel, which project to the spinal cord are especially involved in the control of those fast vertical head movements which occur in conjunction with saccadic eye movements. In contrast the INC-RF projections to the spinal cord are responsible for slower, smaller movements controlling the position of the head in the vertical plane.
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  • 31
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    Annals of hematology 58 (1989), S. 195-199 
    ISSN: 1432-0584
    Keywords: Cytochemistry ; Blood ; Bone marrow ; Leukocytes ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Blood and bone marrow cells of ten clinically healthy cats were stained for alkaline phosphatase (ALP), peroxidase (PO), chloroacetate esterase (CAE), alpha-naphthyl butyrate esterase (NBE), sudanophilia, and periodic acid-Schiff (PAS) reaction. Mature neutrophils in blood and bone marrow were devoid of ALP and NBE, but exhibited modest to strong PO, CAE, sudanophilia, and PAS reaction. In bone marrow, sudanophilia, PO, and CAE were prominent at the promyelocyte stage and diminished with cellular differentiation and maturation, while PAS reactivity increased with cell maturation usually from the myelocyte stage onwards. Myeloblasts were negative for all cytochemical reactions, but some large unidentifiable cells reacted strongly for ALP. Eosinophils were slightly reactive for ALP, CAE, and PAS, but not for PO, sudanophilia, and NBE. Basophil granules stained strongly for CAE, revealed PAS positivity, and stained negatively for PO, NBE, ALP, and sudanophilia. Slight ALP activity was detected in the intergranular cytoplasm of basophils. Lymphocytes and monocytes, with few exceptions, stained negatively. An occasional lymphocyte revealed slight globular NBE activity (NaF-resistant) and diffuse PAS reaction, while an occasional monocyte contained a few PO-positive and sudanophilic granules. Monocytes reacted modestly, whereas bone marrow macrophages reacted strongly for NBE (NaF-sensitive). Cells of the erythroid series stained negatively for all cytochemical reactions, megakaryocytes were PAS-positive, and platelets gave positive reactions for PAS and CAE.
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  • 32
    ISSN: 1573-0832
    Keywords: Sporotrichosis ; Sporothrix schenckii ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The isolation of Sporothrix schenckii from a female European cat it is described. The cat showed lengthened alopecic areas, with prominent nodules in the external surface of the thighs and abdomen. A mycological and histopathological studies of the lesions were carried out. The lesions resolved under treatment with 20% potassium iodide in doses of 0'1 ml/kg oral route in a 8 weeks period.
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  • 33
    ISSN: 1573-9686
    Keywords: Electrical stimulation ; Neural damage ; Peripheral nerve electrode ; Peroneal nerve ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Helical electrodes were implanted around the left and right common peroneal nerves of cats. Three weeks after implantation one nerve was stimulated for 4–16 hours using charge-balanced, biphasic, constant current pulses. Compound action potentials (CAP) evoked by the stimulus were recorded from over the cauda equina before, during and after the stimulation. Light and electron microscopy evaluations were conducted at various times following the stimulation. The mere presence of the electrode invariably resulted in thickened epineurium and in some cases increased peripheral endoneurial connective tissue beneath the electrodes. Physiologic changes during stimulation included elevation of the electrical threshold of the large axons in the nerve. This was reversed within one week after stimulation at a frequency of 20 Hz, but often was not reversed following stimulation at 50–100 Hz. Continuous stimulation at 50 Hz for 8–16 hours at 400 μA or more resulted in neural damage characterized by endoneurial edema beginning within 48 hours after stimulation, and early axonal degeneration (EAD) of the large myelinated fibers, beginning by 1 week after stimulation. Neural damage due to electrical stimulation was decreased or abolished by reduction of the duration of stimulation, by stimulating at 20 Hz (vs. 50 Hz) or by use of an intermittent duty cycle. These results demonstrate that axons in peripheral nerves can be irreversely damaged by 8–16 hours of continuous stimulation at 50 Hz. However, the extent to which these axons may subsequently regenerate is uncertain. Therefore, protocols for functional electrical stimulation in human patients probably should be evaluated individually in animal studies.
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  • 34
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    Cell & tissue research 258 (1989), S. 611-616 
    ISSN: 1432-0878
    Keywords: Cell communication ; Dye-coupling ; Odontoblasts ; Gap junctions ; Dentin sensitivity ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cell communication between odontoblasts was investigated with the use of fluorescent-dye tracers; Lucifer Yellow CH (molecular weight = 457.3), and dextran-Lucifer Yellow CH (average molecular weight = 10000). Dyes were injected into cell bodies of individual odontoblasts via an intracellular microelectrode or into a group of cells through their processes, and passage to adjacent cells was examined with a fluorescence microscope. Lucifer Yellow CH appeared to diffuse very easily among odontoblasts, while dextran-Lucifer Yellow remained within the injected cell or cells. This efficient migration of Lucifer Yellow CH can be considered a functional manifestation of gap junctions between odontoblasts.
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  • 35
    ISSN: 1432-0878
    Keywords: Autonomic ganglia ; Spinal ganglia ; Sensory neurons ; Neurotransmitters ; Sweat glands ; Blood vessels ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The neuronal subpopulations in the cat stellate, lower lumbar and sacral sympathetic ganglia were studied with regard to the cellular distribution of immunoreactivity to tyrosine hydroxylase (TH), acetylcholinesterase (AChE) and various neuronal peptides. Coexistence of neuropeptide Y (NPY)- and galanin (GAL)-like immunoreactivity (LI) was found in a high proportion of the neuronal cell bodies; these cells also contained immunoreactivity to TH, confirming their presumably noradrenergic nature. Some TH- and GAL-immunoreactive principal ganglion cells lacked NPY-LI. Two populations (scattered and clustered) of vasoactive intestinal polypeptide (VIP)- and peptide histidine isoleucine (PHI)-positive cell bodies were found in the sympathetic ganglia studied. The scattered VIP/PHI neurons also contained AChE-LI, calcitonin gene-related peptide (CGRP)-and, following culture, substance P (SP)-LI. The clustered type only contained AChE-LI. In the submandibular and sphenopalatine ganglia, neurons were AChE- and VIP/ PHI-immunoreactive but lacked CGRP- and SP-LI. Many GAL- and occasional TH-positive neurons were found in these ganglia. In the spinal ganglia, single NPY-immunoreactive sensory neuronal cells were observed, in addition to CGRP- and SP-positive neurons. The present results show that there are at least two populations of sympathetic cholinergic neurons in the cat. Retrograde tracing experiments indicate that the scattered type of cholinergic neurons contains four vasodilator peptides (VIP, PHI, CGRP, SP) and provides an important input to sweat glands, whereas the clustered type (containing VIP and PHI) mainly innervates blood vessels in muscles.
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  • 36
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    Cell & tissue research 257 (1989), S. 549-554 
    ISSN: 1432-0878
    Keywords: Salivary secretion ; Parotid gland ; Exocytosis ; Secretory granules ; Autonomic nerve-stimulation ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electron microscopy of cat parotid glands revealed great heterogeneity in the secretory granules of normal unstimulated acinar cells. Electrical stimulation of the parasympathetic nerve to the gland evoked a copious flow of parotid saliva which was accompanied by an extensive depletion of the secretory granules from the acinar cells. Exocytosis was captured as it was occurring by means of perfusion-fixation, and showed that the events occur in a conventional manner. Stimulation of the sympathetic nerve caused only a very small flow of saliva, and no acinar degranulation was detected. It can be concluded that the parasympathetic secretomotor axons provide the main drive for parotid acinar degranulation in the cat. This contrasts with the rat in which sympathetic impulses provide the main stimulus for parotid acinar degranulation. These dissimilarities serve to emphasise how extensively species differences may influence autonomic responses in salivary glands.
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  • 37
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    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989), S. 275-287 
    ISSN: 0271-2091
    Keywords: Curved pipe flow ; Entrance flow ; Finite element method ; Penalty function method ; Experimental validation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A standard Galerkin finite element penalty function method is used to approximate the solution of the three-dimensional Navier-Stokes equations for steady incompressible Newtonian entrance flow in a 90° curved tube (curvature ratio δ = 1/6) for a triple of Dean numbers (κ = 41, 122 and 204). The computational results for the intermediate Dean number (κ = 122) are compared with the results of laser-Doppler velocity measurements in an equivalent experimental model. For both the axial and secondary velocity components, fair agreement between the computational and experimental results is found.
    Additional Material: 7 Ill.
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  • 38
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    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989) 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 39
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    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989), S. 127-150 
    ISSN: 0271-2091
    Keywords: Iterative solution ; Viscous flow ; Generalized conjugate gradient ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We consider the use of accelerated gradient-type iterative methods for solution of Newtonian and certain non-Newtonian (power-law and Bingham models) viscous flow problems. The formulations are based on penalty and mixed finite element methods, and such factors as the effect of the penalty parameter, asymmetry, continuation and preconditioning are examined.
    Additional Material: 19 Ill.
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  • 40
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    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989), S. 151-165 
    ISSN: 0271-2091
    Keywords: Numerical analysis ; Fluid flow ; Rotating circular duct ; Finite cell method ; Finite element method ; Swirl ; Inlet boundary conditions ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A numerical analysis of the flow pattern in the inlet region of a circular pipe rotating steadily about an axis parallel to its own is presented. Both finite cell and finite element methods are used to analyse the problem and they give qualitatively similar results which show that a swirling fluid motion is induced in the pipe inlet region. The analyses show that the direction of swirl is opposite to that of the pipe rotation when viewed along the flow axis and that its magnitude depends on the speed of pipe rotation and throughflow Reynolds number. Neither numerical analysis predicts the marked upturn in friction factor (or pressure drop) which has been observed experimentally. However, a dependence on the pipe inlet boundary conditions is demonstrated.
    Additional Material: 9 Ill.
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  • 41
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 185-191 
    ISSN: 0271-2091
    Keywords: Stokes equations ; Boundary elements ; Quadrature ; Triangular co-ordinates ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A collocation-type boundary element method based on bilinear B-splines is used for the numerical solution of the Stokes Dirichlet problem in bounded domains D ⊂ R3. The computation of the influence matrix requires the numerical evaluation of weakly singular integrals on the domain boundary if the usual double-layer potential ansatz is chosen. Here mostly standard methods with disjoint grids for collocation and integration are used. We develop a special integration scheme based on triangular co-ordinates near the singularity and show its efficiency compared with the method mentioned above.
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  • 42
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    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989), S. 193-212 
    ISSN: 0271-2091
    Keywords: Navier-Stokes ; Staggered grid ; Primitive variable formulation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Nine finite difference schemes using primitive variables on various grid arrangements were systematically tested on a benchmark problem of two-dimensional incompressible Navier-Stokes flows. The chosen problem is similar to the classical lid-driven cavity flow, but has a known exact solution. Also, it offers the reader an opportunity to thoroughly evaluate accuracies of various conceptual grid arrangements.Compared to the exact solution, the non-staggered grid scheme with higher-order accuracy was found to yield an accuracy significantly better than others. In terms of ‘overall performance’, the so-called 4/1 staggered grid scheme proved to be the best. The simplicity of this scheme is the primary benefit. Furthermore, the scheme can be changed into a non-staggered grid if the pressure is replaced by the pressure gradient as a field variable.Finally, the conventional staggered grid scheme developed by Harlow and Welch also yields relatively high accuracy and demonstrates satisfactory overall performance.
    Additional Material: 5 Ill.
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  • 43
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 251-262 
    ISSN: 0271-2091
    Keywords: Theodorsen's method ; Incompressible flow ; Aerofoil theory ; Thickness ratio ; Camber ratio ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Theodorsen's method for calculating the incompressible potential flow past an aerofoil is viewed afresh. It is found that some simple modifications to the computational process make the computations relatively faster, easier and more accurate. The new modifications are applicable to the analysis of conventional aerofoils with up to moderate thickness and camber ratios. Several examples are presented to show the effectiveness of the modifications.
    Additional Material: 2 Ill.
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  • 44
    ISSN: 0271-2091
    Keywords: Navier-Stokes equations ; Euler equations ; Finite element ; Hypersonic laminar-viscous flow ; Time marching ; Shock wave interactions ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An upwind finite element technique that uses cell-centred quantities and implicit and/or explicit time marching has been developed for computing hypersonic laminar viscous flows using adaptive triangular grids. The approach is an extension to unstructured grids of the LAURA algorithm due to Gnoffo. A structured grid of quadrilaterals is laid out near a solid surface. For inviscid flows the method is stable at Courant numbers of over 100000. A first-order basic scheme and a higher-order flux-corrected transport (FCT) scheme have been implemented. This technique has been applied to the problem of predicting type III and IV shock wave interactions on a cylinder, with a view to simulating the pressure and heating rate augmentation caused by an impinging shock on the leading edge of a cowl lip of an engine inlet. The predictions of wall pressure and heating rates compare very well with experimental data. The flow features are distinctly captured with a sequence of adaptively generated grids.
    Additional Material: 12 Ill.
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  • 45
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 623-650 
    ISSN: 0271-2091
    Keywords: Numerical analysis ; Wave propagation ; Hyperbolic equations ; Quantum mechanics ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The analysis of wave propagation in computing domains where hyperbolic equations are approximated with finite differences has revealed surprising analogies between this subject and quantum mechanics. The first part of this paper consists of a review of the corresponding phenomena and of their description with known results from numerical analysis and wave propagation theory. We then introduce a new formalism, containing a finite difference analogue of the classical Schrodinger equation, which describes the ensemble of those phenomena. The validity of the new formalism is verified by its agreement with known theoretical results in numerical wave propagation (it contains in fact many of those results) as well as with new data obtained in numerical experiments with monochromatic waves which display properties similar to those of Schrödinger's wavefunction for the quantum mechanics description of the equivalent experiments with physical particles. While the results of this paper are derived in the context of wave propagation in computing domains, they remain applicable to similar aspects of wave propagation in other (physical) periodic structures.
    Additional Material: 16 Ill.
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  • 46
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    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989), S. 689-712 
    ISSN: 0271-2091
    Keywords: Rotating spheres ; Viscous flow ; Incompressible fluid ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The research reported herein involved the study of the transient motion of a system consisting of an incompressible Newtonian fluid in an annulus between two concentric, rotating, rigid spheres. The primary purpose of the research was to study the use of a numerical method for analysing the transient motion that results from the interaction between the fluid in the annulus and the spheres which are started suddenly by the action of prescribed torques. The problems considered in this research included cases where: (a) one or both spheres rotate with prescribed constant angular velocities and (b) one sphere rotates due to the action of an applied constant or impulsive t̰orque.In this research the coupled solid and fluid equations were solved numerically by employing the finite difference technique. With the approach adopted in this research, only the derivatives with respect to spatial variables were approximated with the use of the finite difference formulae. The steady state problem was also solved as a separate problem (for verification purposes), and the results were compared with those obtained from the solution of the transient problem. Newton's algorithm was employed to solve the algebraic equations which resulted from the steady state problem, and the Adams fourth-order predictor-corrector method was employed to solve the ordinary differential equations for the transient problem. Results were obtained for the streamfunction, circumferential function, angular velocity of the spheres and viscous torques acting on the spheres as a function of time for various values of the system dimensionless parameters.
    Additional Material: 22 Ill.
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  • 47
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 747-761 
    ISSN: 0271-2091
    Keywords: Navier-Stokes solutions ; Shock wave/boundary layer interactions ; Newton's iteration ; Upwind differencings ; Symmetric line relaxation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The objective of the paper is twofold. First we describe an upwind/central differencing method for solving the steady Navier-Stokes equations. The symmetric line relaxation method is used to solve the resulting algebraic system to achieve high computational efficiency. The grid spacings used in the calculations are determined from the triple-deck theory, in terms of Mach and Reynolds numbers and other flow parameters. Thus the accuracy of the numerical solutions is improved by comparing them with experimental, analytical and other computational results. Secondly we proceed to study numerically the shock wave/boundary layer interactions in detail, with special attention given to the flow separation. The concept of free interaction is confirmed. Although the separated region varies with Mach and Reynolds numbers, we find that the transverse velocity component behind the incident shock, which has not been identified heretofore, is also an important parameter. A small change of this quantity is sufficient to eliminate the flow separation entirely.
    Additional Material: 12 Ill.
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  • 48
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 921-941 
    ISSN: 0271-2091
    Keywords: Blade design ; Compressors ; Turbines ; Navier-Stokes ; Quasi-3D and 3D systems ; Through-flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The paper describes the basic components of a turbomachinery blade design system in use within Rolls-Royce. A number of modelling aspects of the advanced computational methods in use and under development are reviewed together with areas for future research and development.A quasi-3D blade design system which is used for both compressors and turbines is described covering through-flow and blade-to-blade analysis. Various features of blade-to-blade analysis are discussed including the use of compatible design and analysis modes and coupled boundary layer analysis capable of handling attached and separated flow; examples are included to show capabilities. Advances being made in the development and application of Reynolds-averaged Navier-Stokes models are covered showing capabilities with regard to loss and heat transfer prediction.A fully coupled quasi-3D through-flow and blade-to-blade analysis system is described and results presented to show basic capabilities.The need for 3D flow analysis is discussed and the elements of a 3D blade design system presented showing how this links to the traditional quasi-3D system. Examples are given showing basic capabilities of the methods available and under development.Finally areas for future development are presented indicating the mathematical and numerical modelling problems to be addressed.
    Additional Material: 22 Ill.
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  • 49
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1011-1024 
    ISSN: 0271-2091
    Keywords: Inviscid flow ; TVD difference scheme ; Shock wave ; Expansion wave ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An improved treatment for the Harten-Yee and Chakravarthy-Osher TVD numerical flux functions in general co-ordinates is presented. The proposed formulation is demonstrated by a series of numerical experiments for three-dimensional flows around the ONERA-M6 wing. The numerical results indicate that it is important to use a suitable artificial compression parameter in order to obtain more accurate solutions around the leading edge of the wing. The two TVD numerical fluxes give excellent results: they capture the shock wave without numerical oscillations, they capture the rapid expansion around the leading edge sharply, they have self-adjusting mechanisms regarding numerical viscosity and they also have robustness.
    Additional Material: 7 Ill.
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  • 50
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1025-1050 
    ISSN: 0271-2091
    Keywords: Unsteady Navier-Stokes equations ; Direct solution method ; Block Gaussian elimination ; Backstep channel ; Incompressible separated flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The unsteady incompressible Navier-Stokes equations are formulated in terms of vorticity and stream-function in generalized curvilinear orthogonal co-ordinates to facilitate analysis of flow configurations with general geometries. The numerical method developed solves the conservative form of the vorticity transport equation using the alternating direction implicit method, whereas the streamfunction equation is solved by direct block Gaussian elimination. The method is applied to a model problem of flow over a backstep in a doubly infinite channel, using clustered conformal co-ordinates. One-dimensional stretching functions, dependent on the Reynolds number and the asymptotic behaviour of the flow, are used to provide suitable grid distribution in the separation and reattachment regions, as well as in the inflow and outflow regions. The optimum grid distribution selected attempts to honour the multiple length scales of the separated flow model problem. The asymptotic behaviour of the finite differenced transport equation near infinity is examined and the numerical method is carefully developed so as to lead to spatially second-order-accurate wiggle-free solutions, i.e. with minimum dispersive error. Results have been obtained in the entire laminar range for the backstep channel and are in good agreement with the available experimental data for this flow problem, prior to the onset of three-dimensionality in the experiment.
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  • 51
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1073-1086 
    ISSN: 0271-2091
    Keywords: k-∊ turbulence model ; Compressible flow ; Bulk dilatation ; Reciprocating engine flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper is concerned with simulation of the mean flow and turbulence evolution in a model engine and comparison of the behaviour of certain important turbulence parameters, namely the intensity, length scale and dissipation time scale, as predicted by three variants of the k-∊ model developed for application to strongly compressible flows. The predictions pertain to the axisymmetric, disc-chamber, four-stroke, Imperial College model engine operating at 200 rpm and compression ratios of 3·5 and 6·7. The paper analyses the predicted variations of these parameters during the induction, compression and expansion strokes and identifies the versions that produce the most consistent and physically plausible variations. The significance, to the turbulence evolution, of the ratio of the turbulence dissipation time scale to the time scale of compression/expansion is also discussed. It is concluded that on these grounds the Morel-Mansour and El Tahry versions are, and the Watkins version is not, suitable for engine applications.
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  • 52
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1121-1143 
    ISSN: 0271-2091
    Keywords: Turbulence ; High-speed flows ; Unstructured grids ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The incorporation of algebraic turbulence models in a solver for the 2D compressible Navier-Stokes equations using triangular grids is described. A practical way to use the Cebeci-Smith model and to modify it in separated regions is proposed. The ability of the model to predict high-speed perfect-gas boundary layers is investigated from a numerical point of view.
    Additional Material: 22 Ill.
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  • 53
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1179-1182 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 54
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1195-1206 
    ISSN: 0271-2091
    Keywords: Free boundary problem ; Potential flow ; Wave resistance ; BEM ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this paper a numerical method to compute the wave resistance of a body submerged in a free stream of finite and infinite depth is presented. Non-linear effects on the free surface are taken into account by an iterative procedure; the solution is in the form of a single-layer potential. For the 2D problem, results are shown for both the cases of finite and infinite depth of the fluid domain, with special emphasis on the supercritical flow in which the consistency of the scheme is pointed out. The method is also extended to the 3D case of a spheroid submerged in deep water. All the results presented are compared with experimental data and analytical solutions available in the literature.
    Additional Material: 7 Ill.
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  • 55
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1235-1267 
    ISSN: 0271-2091
    Keywords: Pseudospectral ; Non-periodic ; Incompressible flows ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The reduction-to-periodicity method using the pseudospectral fast Fourier transform (FFT) technique is applied to the solution of non-periodic problems, including the two-dimensional incompressible Navier-Stokes equations. The accuracy of the method is explored by calculating the derivatives of given functions, one- and two-dimensional convective-diffusive problems, and by comparing the relative errors due to the FFT method with a second-order finite difference (FD) method. Finally, the two-dimensional Navier-Stokes equations are solved by a fractional step procedure using both the FFT and the FD methods for the driven cavity flow and the backward-facing step problems. Comparisons of these solutions provide a realistic assessment of the FFT method.
    Additional Material: 26 Ill.
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  • 56
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1269-1283 
    ISSN: 0271-2091
    Keywords: Euler equations ; Real gases ; Local parametrization of the equation of state ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An efficient algorithm is presented for the solution of the Euler equations of gas dynamics with a general convex equation of state. The scheme is based on solving linearized Riemann problems approximately, and in more than one dimension incorporates operator splitting. In particular, only one function evaluation in each computational cell is required by using a local parametrization of the equation of state. The scheme is applied to two standard test problems in gas dynamics for some specimen equations of state.
    Additional Material: 7 Ill.
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  • 57
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1145-1164 
    ISSN: 0271-2091
    Keywords: Riemann problem ; Covolume ; Random choice ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The Riemann problem for the unsteady one-dimensional Euler equations together with the constant-covolume equation of state is solved exactly. The solution is then applied to the random choice method to solve the general initial-boundary value problem for the Euler equations. The iterative procedure to find p*, the pressure between the acoustic waves, involves a single algebraic (non-linear) equation, all other quantities follow directly throughout the x-t plane, except within rarefaction fans where an extra iterative procedure is required. The solution is validated against existing exact results both directly and in conjunction with the random choice method.
    Additional Material: 11 Ill.
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  • 58
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    International Journal for Numerical Methods in Fluids 9 (1989) 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 59
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1207-1219 
    ISSN: 0271-2091
    Keywords: Centre implicit method ; Pressure transients ; Two-phase pipe flow ; Bubbly pipe flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper presents a two-dimensional model for the analysis of the pressure transient of a two-phase homogeneous bubbly mixture flowing in a pipeline and the numerical integration using the centre implicit method (CIM). Experiments were conducted to confirm the proposed sonic speed equation of an air-water mixture for an air concentration of less than 1%. The 2D CIM model is compared with the method of characteristics (MoC) for a two-phase bubbly flow in a pipeline. The comparisons show that the proposed 2D CIM model generally gives good agreement with the method of characteristics.
    Additional Material: 7 Ill.
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  • 60
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1299-1301 
    ISSN: 0271-2091
    Keywords: Navier-Stokes equation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In a recent paper a generalized potential flow theory and its application to the solution of the Navier-Stokes equation are developed.1 The purpose of this comment is to show that the analysis presented in that paper is in general not correct. We note that the theoretical development of Reference 1 is in fact an extension - although not cited - of some work first done by Hawthorne for steady inviscid flow.2 Hawthorne's solution is correct, and his analysis, which we briefly describe, provides a useful introduction to this note.
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  • 61
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    International Journal for Numerical Methods in Fluids 9 (1989) 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 62
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1395-1411 
    ISSN: 0271-2091
    Keywords: Reduced Navier-Stokes computations ; Flow separation ; Laminar instability ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The convergence properties of an iterative solution technique for the Reduced Navier-Stokes equations are examined for two-dimensional steady subsonic flow over bump and trough geometries. Techniques for decreasing the sensitivity to the initial pressure approximation, for fine meshes in particular, are investigated. They are shown to improve the robustness of the relaxation process and to decrease the computational work required to obtain a converged solution. A semi-coarsening multigrid technique that has previously been found to be particularly advantageous for high-Reynolds-number (Re) flows with flow separation and with highly stretched surface-normal grids is applied herein to further accelerate convergence. Solutions are obtained for the laminar flow over a trough that is more severe than has been considered to date. Sufficient axial grid refinement in this case leads to a shock-like reattachment and, for sufficiently large Re, to a local ‘divergence’ of the numerical computations. This ‘laminar flow breakdown’ appears to be related to an instability associated with high-frequency fine-grid modes that are not resolvable with the present modelling. This behaviour may be indicative of dynamic stall or of incipient transition. The breakdown or instability is shown to be controllable by suitable introduction of transition turbulence models or by laminar flow control, i.e. small amounts of wall suction. This lends further support to the hypothesis that the instability is of a physical rather than numerical character and suggests that full three-dimensional analysis is required to properly capture the flow behaviour. Another inference drawn from this investigation is that there is a need for careful grid refinement studies in high-Re flow computations, since coarser grids may yield oscillation-free solutions that cannot be obtained on finer grids.
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  • 63
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1453-1467 
    ISSN: 0271-2091
    Keywords: Fourier wave theory ; Limit wave ; Stream function ; Truncation order ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A review of the analytical and numerical background of Fourier wave theory establishes the commonality of existing formulations and identifies a number of analytical and numerical assumptions that are unnecessary. Some formulations in particular lack flexibility in excluding the possibility of Stokes' second definition of phase speed. A generalized formulation is introduced for comparative purposes and it is shown that published solutions differ only in the approach to the limit wave. Detailed consideration of truncation order confirms that it is the crucial parameter, especially at extreme wave heights. All formulations considered are shown to provide acceptable solutions for small to moderately extreme waves.
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  • 64
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1487-1501 
    ISSN: 0271-2091
    Keywords: Viscoelastic fluid ; Polymer flow ; Velocity correction method ; Two-step explicit scheme ; Pressure boundary condition ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The effects of non-Newtonian behaviour of a fluid and unsteadiness on flow in a channel with non-uniform cross-section have been investigated. The rheological behaviour of the fluid is assumed to be described by the constitutive equation of a viscoelastic fluid obeying the Oldroyd-B model. The finite element method is used to analyse the flow. The novel features of the present method are the adoption of the velocity correction technique for the momentum equations and of the two-step explicit scheme for the extra stress equations. This approach makes the computational scheme simple in algorithmic structure, which therefore implies that the present technique is capable of handling large-scale problems. The scheme is completed by the introduction of balancing tensor diffusivity (wherever necessary) in the momentum equations. It is important to mention that the proper boundary condition for pressure (at the outlet) has been developed to solve the pressure Poisson equation, and then the results for velocity, pressure and extra stress fields have been computed for different values of the Weissenberg number, viscosity due to elasticity, etc. Finally, it is pertinent to point out that the present numerical scheme, along with the proper boundary condition for pressure developed here, demonstrates its versatility and suitability for analysing the unsteady flow of viscoelastic fluid through a channel with non-uniform cross-section.
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  • 65
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 23-41 
    ISSN: 0271-2091
    Keywords: Momentum transport ; Turbulent mixing layers ; Discrete vortex method ; Time-dependent momentum fluctuations ; Comparison with experiments ; Large-scale structures ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The turbulent momentum transport phenomena in a two-dimensional mixing layer are investigated numerically by a discrete vortex method. The numerical model and calculations are verified through a comparison with existing numerical simulations and experimental measurements. The main emphasis is placed on the exploration of the detailed time-dependent instantaneous local momentum fluctuations and on the comparison of numerical results with available experimental measurements. The current simulations confirm qualitatively the various trends in the turbulent momentum flux and fluctuating components of the velocity in the mixing layer found with several experimental results. The study shows that similarity exists in turbulent momentum quantities along the axial direction of the mixing layer. The calculations also show a definite correlation between the passage of a large-scale structure and a burst in the turbulent momentum flux. The probability density functions of the fluctuating quantities are shown to be mostly Gaussian-like, with only a few exceptions.
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  • 66
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 9-22 
    ISSN: 0271-2091
    Keywords: Shock capturing ; Shock tube ; TVD scheme ; Compressible flow ; Fluid dynamics ; Comparison with experiment ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Harten's second-order-accurate total-variation-diminishing (TVD) scheme is applied to calculation of flow from the open end of a shock tube. Comparison of numerical results with available experimental data for overpressure at selected points around the shock tube exit shows good agreement. Numerically indicated positions of the moving shock front and Mach stem also compare well with flow shadowgraph data. Where the problem geometry is sufficiently simple and rectangular gridding can be used, Harten's method affords a good choice for blast wave calculations.
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  • 67
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 59-73 
    ISSN: 0271-2091
    Keywords: Steady Euler equations ; Transonic flows ; Multigrid methods ; Boundary conditions ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Steady 2D Euler flow computations have been performed for a wind tunnel section, designed for research on transonic shock wave-boundary layer interaction. For the discretization of the steady Euler equations, an upwind finite volume technique has been applied. The solution method used is collective, symmetric point Gauss-Seidel relaxation, accelerated by non-linear multigrid. Initial finest grid solutions have been obtained by nested iteration. Automatic grid adaptation has been applied for obtaining sharp shocks. An indication is given of the mathematical quality of four different boundary conditions for the outlet flow. Two transonic flow solutions with shock are presented: a choked and a non-choked flow. Both flow solutions show good shock capturing. A comparison is made with experimental results.
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  • 68
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 113-120 
    ISSN: 0271-2091
    Keywords: Steady Navier-Stokes equations ; Partial flux splitting ; Multigrid methods ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Flux splitting is applied to the convective part of the steady Navier-Stokes equations for incompressible flow. Partial upwind differences are introduced in the split first-order part, while central differences are used in the second-order part. The discrete set of equations obtained is positive, so that it can be solved by collective variants of relaxation methods. The partial upwinding is optimized in the same way as for a scalar convection-diffusion equation, but involving several Peclet numbers. It is shown that with the optimum partial upwinding accurate results can be obtained. A full multigrid method in W-cycle form, using red-black successive under-relaxation, injection and bilinear interpolation, is described. The efficiency of this method is demonstrated.
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  • 69
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 167-183 
    ISSN: 0271-2091
    Keywords: Axisymmetric turbulent flow ; Combustors ; Diffusers ; Navier-Stokes equations k-∊ model ; Zonal grid ; Finite differences ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Numerical studies of turbulent flow in an axisymmetric 45° expansion combustor and bifurcated diffuser are presented. The Navier-Stokes equations incorporating a k-∊ model were solved in a non-orthogonal curvillinear co-ordinate system. A zonal grid method, wherein the flow field was divided into several subsections, was developed. This approach permitted different computational schemes to be used in the various zones. In addition, grid generation was made a more simple task. However, treatment of the zonal boundaries required special handling. Boundary overlap and interpolating techniques were used and an adjustment of the flow variables was required to assure conservation of mass flux. Three finite differencing methods - hybrid, quadratic upwind and skew upwind - were used to represent the convection terms. Results were compared with existing experimental data. In general, good agreement between predicted and measured values was obtained.
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  • 70
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 235-244 
    ISSN: 0271-2091
    Keywords: Process splitting ; Advection-dispersion equation ; Boundary conditions ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Rational strategies are considered for the specification of the intermediate boundary condition at an inflow boundary where process splitting (fractional steps) is adopted in solving the advection-dispersion equation. Three lowest-order methods are initially considered and evaluation is based on comparisons with an analytical solution. For flow and dispersion parameter ranges typical of rivers and estuaries, the given boundary condition for the complete advection-dispersion equation at the end of the complete time step provides a satisfactory estimate of the intermediate boundary value. This was further confirmed by the development and evaluation of two higher-order methods. These required non-centred discrete approximations for spatial derivatives, which offset any special advantages from the higher truncation error order.
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  • 71
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 250-250 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 72
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 263-273 
    ISSN: 0271-2091
    Keywords: Low-Reynolds-number flow ; Sedimentation ; Hydrodynamic interactions ; Two-phase flows ; Suspensions ; Boundary element method ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A new method for the simulation of the translational and rotational motions of a system containing a sedimenting particle interacting with a neutrally buoyant particle has been developed. The method is based on coupling the quasi-static Stokes equations for the fluid with the rigid body equations of motion for the particles. The Stokes equations are solved at each time step with the boundary element method. The stresses are then integrated over the surface of each particle to determine the resultant forces and moments. These forces and moments are inserted into the rigid body equations of motion to determine the translational and rotational motions of the particles. Unlike many other simulation techniques, no restrictions are placed on the shape of the particles. Superparametric boundary elements are employed to achieve accurate geometric representations of the particles. The simulation method is able to predict the local fluid velocity, resolve the forces and moments exerted on the particles, and track the particle trajectories and orientations.
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  • 73
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 369-373 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 74
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 363-368 
    ISSN: 0271-2091
    Keywords: Silencers ; Noise attenuation ; Shock flow ; Numerical simulation ; Gas dynamics ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The problem of attenuating the noise from weapons firing is studied experimentally and numerically. As a possible method of attenuating the noise significantly, a silencer with no internal baffles is attached to the M242 cannon. The internal pressures inside the muffler are measured. The near-field overpressures outside the muffler at various polar angles are also measured. A numerical simulation of the flow through the muffler is performed, using Harten's shock-capturing method to solve the Euler equations of ideal compressible flow. The numerical simulation yields a detailed picture of the flow field as displayed by the pressure and Mach contours. Pressure-time curves at selected locations are obtained and compared with experimental data. There is good agreement, except that the numerical simulation generates more vigorous oscillations.
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  • 75
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 341-362 
    ISSN: 0271-2091
    Keywords: Unsteady ; Fluid flow ; Navier-Stokes ; Simulation ; SIMPLE ; PRIME ; QUICK ; ICCG ; MG ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This work builds on a SIMPLE-type code to produce two numerical codes of greatly improved speed and accuracy for solution of the Navier-Stokes equations. Both implicit and explicit codes employ an improved QUICK (quadratic upstream interpolation for convective kinematics) scheme to finite difference convective terms for non-uniform grids. The PRIME (update pressure implicit, momentum explicit) algorithm is used as the computational procedure for the implicit code. Use of both the ICCG (incomplete Cholesky decomposition, conjugate gradient) method and the MG (multigrid) technique to enhance solution execution speed is illustrated. While the implicit code is first-order in time, the explicit is second-order accurate. Two- and three-dimensional forced convection and sidewall-heated natural convection flows in a cavity are chosen as test cases. Predictions with the new schemes show substantial computational savings and very good agreement when compared to previous simulations and experimental data.
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  • 76
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 374-374 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 77
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1087-1098 
    ISSN: 0271-2091
    Keywords: RNS ; Separation ; Direct solver ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The reduced Navier-Stokes and thin layer approximations to the Navier-Stokes equations are used to obtain solutions for viscous subsonic three-dimensional flows. A spatial marching method is combined with a direct sparse matrix solver to obtain successive solutions in a global relaxation process. Results have been obtained for flow fields with and without regions of flow reversal.
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  • 78
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1113-1119 
    ISSN: 0271-2091
    Keywords: Finite element ; Free streamlines ; Wakes ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A model having velocity components as basic unknowns is presented for calculation of two-dimensional flow past a symmetric profile with a wake in a channel. A modified least squares functional is used for the finite element solution of velocities. The determination of the position of the free streamline is treated as an optimum design problem. The concepts of cost function, geometry parameter and sensitivity derivative are employed. Numerical results are compared with published results obtained with streamfunction formulations.
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  • 79
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1165-1177 
    ISSN: 0271-2091
    Keywords: Laminar flow ; Triangular step ; FEM ; Velocity correction ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The velocity correction algorithm is used in the finite element method to solve forced convection problems between parallel plates with a triangular step, for Reynolds numbers up to 1000. Equal-order interpolation functions for velocity, pressure and temperature are used. The solutions show a smooth variation of pressure. The streamfunction, isotherms, isobars and velocity profiles are presented for a typical Reynolds number of 500. The skin friction and heat transfer results are presented for Reynolds numbers up to 1000.
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  • 80
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1183-1193 
    ISSN: 0271-2091
    Keywords: CFD ; Transonics ; Streamfunction co-ordinates ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A new method has been developed for the computation of steady two-dimensional full-potential transonic flow past symmetric aerofoils. This method utilizes von Mises variables (x, ψ), where ψ is taken as the streamfunction for the flow. The flow equations and appropriate boundary conditions are formulated in terms of the von Mises variables (x, ψ) for symmetric aerofoils at zero incidence. This yields a system of two equations for unknowns ρ(x, ψ) and y(x, ψ). Finite difference solutions have been computed using SLOR at subcritical and supercritical Mach numbers. The results are compared with available data and are in excellent agreement.
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  • 81
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1221-1234 
    ISSN: 0271-2091
    Keywords: Biharmonic equation ; Stokes flow ; Simple layer potential ; Method of fundamental solutions ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A novel formulation of the method of fundamental solutions for the numerical solution of plane biharmonic problems, based on the simple layer potential representation of Fichera, is presented. The applicability and accuracy of the method are demonstrated by examining its performance on a set of practical problems arising in Stokes fluid flow.
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  • 82
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1285-1298 
    ISSN: 0271-2091
    Keywords: Navier-Stokes equations ; Vorticity-velocity ; Multiconnected domains ; Pressure single-valuedness ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The thermofluid dynamic fields in two-dimensional multiconnected domains are analysed by solving the Navier-Stokes equations with the Boussinesq approximation in the vorticity-velocity formulation. The need of an integral condition for the pressure to be single-valued on each independent irreducible loop, in analogy with the ω-Ψ formulation, is demonstrated. The field equations are discretized by a finite difference technique and solved at the steady state via an alternating direction implicit method of a scalar type. Two test cases at low Reynolds and Rayleigh numbers are considered: the multiconnected driven cavity and an annulus with isothermal walls and stationary or rotating inner cylinder.
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  • 83
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1302-1304 
    ISSN: 0271-2091
    Keywords: Incompressible flow ; Clebsch potentials ; Three-dimensional ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A recent paper by W. Zijl, which reformulated the Navier-Stokes and Boussinesq equations in terms of Clebsch potentials, has an error that greatly reduces the generality of the results. Some other recent efforts to use such potentials in fluid and plasma dynamics are briefly discussed.
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  • 84
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 569-582 
    ISSN: 0271-2091
    Keywords: Flow analysis ; Free surface problem ; Finite element method ; Blast furnace ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A sharp interface problem arising in the flow of two immiscible fluids, slag and molten metal in a blast furnace, is formulated using a two-dimensional model and solved numerically. This problem is a transient two-phase free or moving boundary problem, the slag surface and the slag-metal interface being the free boundaries. At each time step the hydraulic potential of each fluid satisfies the Laplace equation which is solved by the finite element method. The ordinary differential equations determining the motion of the free boundaries are treated using an implicit time-stepping scheme. The systems of linear equations obtained by discretization of the Laplace equations and the equations of motion of the free boundaries are incorporated into a large system of linear equations. At each time step the hydraulic potential in the interior domain and its derivatives on the free boundaries are obtained simultaneously by solving this linear system of equations. In addition, this solution directly gives the shape of the free boundaries at the next time step. The implicit scheme mentioned above enables us to get the solution without handling normal derivatives, which results in a good numerical solution of the present problem. A numerical example that simulates the flow in a blast furnace is given.
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  • 85
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 943-962 
    ISSN: 0271-2091
    Keywords: Navier-Stokes solver ; Vortex motion ; Finite volume method ; Viscous flow ; Delta wing ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A 3D Navier-Stokes solver has been developed to simulate laminar compressible flow over quadrilateral wings. The finite volume technique is employed for spatial discretization with a novel variant for the viscous fluxes. An explicit three-stage Runge-Kutta scheme is used for time integration, taking local time steps according to the linear stability condition derived for application to the Navier-Stokes equations. The code is applied to compute primary and secondary separation vortices at transonic speeds over a 65° swept delta wing with round leading edges and cropped tips. The results are compared with experimental data and Euler solutions, and Reynolds number effects are investigated.
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  • 86
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1059-1072 
    ISSN: 0271-2091
    Keywords: Viscoelastic flow ; Leonov model ; Convective integration ; Finite element method ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The finite element method is used to find the elastic strain (and thus the stress) for given velocity fields of the Leonov model fluid. With a simple linearization technique and the Galerkin formulation, the quasi-linear coupled first-order hyperbolic differential equations together with a non-linear equality constraint are solved over the entire domain based on a weighted residual scheme. The proposed numerical scheme has yielded efficient and accurate convective integrations for both the planar channel and the diverging radial flows for the Leonov model fluid. Only the strain in the inflow plane is required to be prescribed as the boundary conditions. In application, it can be conveniently incorporated in an existing finite element algorithm to simulate the Leonov viscoelastic fluid flow with more complex geometry in which the velocity field is not known a priori and an iterative procedure is needed.
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  • 87
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1321-1329 
    ISSN: 0271-2091
    Keywords: Peaceman-Rachford ADI method ; Method of sweeps ; Central differences of o(h2; k2) ; Rotating viscous fluid ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The flow of steady incompressible viscous fluid rotating about the z-axis with angular velocity ω and moving with velocity u past a sphere of radius a which is kept fixed at the origin is investigated by means of a numerical method for small values of the Reynolds number Reω. The Navier-Stokes equations governing the axisymmetric flow can be written as three coupled non-linear partial differential equations for the streamfunction, vorticity and rotational velocity component. Central differences are applied to the partial differential equations for solution by the Peaceman-Rachford ADI method, and the resulting algebraic equations are solved by the ‘method of sweeps’.The results obtained by solving the non-linear partial differential equations are compared with the results obtained by linearizing the equations for very small values of Reω. Streamlines are plotted for Ψ = 0·05, 0·2, 0·5 for both linear and non-linear cases. The magnitude of the vorticity vector near the body, i.e. at z = 0·2, is plotted for Reω = 0·05, 0·24, 0·5. The correction to the Stokes drag as a result of rotation of the fluid is calculated.
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  • 88
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1413-1426 
    ISSN: 0271-2091
    Keywords: Impinging jet ; MacCormack implicit scheme ; Implicit bidiagonal numerical method ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Two-dimensional normal impinging jet flowfields, with or without an upper plate, were analysed by employing an implicit bidiagonal numerical method developed by Lavante and Thompkins Jr. The Jones-Launder K-∊ two-equation turbulent model was employed to study the turbulent effects of the impinging jet flowfield. The upper plate surface pressure, the ground plane pressure and other physical parameters of the momentum flowfield were calculated at various jet exit height and jet inlet Reynolds numbers. These results were compared with those of Beam and Warming's numerical method, Hsiao and Chuang, and others, along with experimental data. The potential core length of the impinging jet without an upper plate is longer than that of the free jet because of the effects of the ground plane, while the potential core length of the impinging jet with an upper plate is shorter than that of the free jet because of the effects of the upper plate. This phenomenon in the present analysis provides a fundamental numerical study of an impinging jet and a basis for further analysis of impinging jet flowfields on a variable angle plate.
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  • 89
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    International Journal for Numerical Methods in Fluids 9 (1989) 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 90
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1431-1451 
    ISSN: 0271-2091
    Keywords: Probabilistic diffusion-convection equation ; Gaussian field approach ; Random walk method ; Fluctuation Peclet number ; Porous media ; Two-phase system ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The channels formed between individual particles in porous media have variable dimensions and orientations. The porosity, permeability and its anisotropy exhibit random spatial distributions. The probabilistic approach can effectively describe the transport of contaminants through porous media and is analysed in this paper. Numerical results are obtained by considering (I) random dispersion coefficients without and with spatial structure, (II) random time distribution of concentration at the inlet boundary, (III) random velocity distribution in the flow field without and (IV) with variable dispersion coefficient, (V) non-linearity of the governing equation and (VI) anisotropy of the dispersion coefficient. Two methods are used for probabilistic predictions: (1) Gaussian field approach in conjunction with Monte Carlo method and (2) random walk method. The input random parameters are assumed to have normal and log-normal distributions according to available experimental data. The probability distribution functions of the contaminant concentration at different locations within the flow domain are calculated and compared with the input distributions as a function of the mean and fluctuation Peclet numbers. The one-dimensional case is analysed in detail and the illustrative numerical predictions are compared with analytical and experimental results. The extension to a two-dimensional domain is discussed in the last part of this paper.
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  • 91
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    International Journal for Numerical Methods in Fluids 9 (1989), S. 1539-1542 
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 92
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    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 459-476 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: A closed-form analysis for elastic - plastic response of a circular hole in an infinite Mohr - Coulomb medium under axisymmetric loading shows the effect of repeated loading on the stress and displacement fields around the hole. Examples show how repeat-load closure increment is affected by working load, internal pressure, material compressive strength and internal friction. The solution is used to predict results of a laboratory test performed on a rock simulant specimen that contained a reinforced hole. Analytical and laboratory results are similar: at small closures (a few per cent, but well into the plastic response range), the closure increment from an unload - reload cycle is small compared with the initial closure. Closure increments for each of several cycles are comparable and cumulative.
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  • 93
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    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 531-550 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: A new semi-analytical solution for the transport of a conservative contaminant species in a fractured medium having a regular two- or three-dimensional fracture network is presented. The application of the technique and some of the practical implications arising from an examination of contaminant migration in fractured systems is discussed. Particular consideration is given to the effects of Darcy velocity, fracture spacing, matrix porosity, dispersivity and the mass of contaminant available for transport. The implications of uncertainty with respect to fracture opening size and ground-water velocity is also discussed and it is shown that provided one can obtain a reasonable estimate of the hydraulic gradient and hydraulic conductivity for the rock mass, uncertainty regarding the magnitude of the opening size and the groundwater velocity does not have a significant effect on predicted contaminant migration for the class of problems being considered.
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  • 94
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    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 551-564 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: A numerical technique has been implemented to perform strain path analyses for arbitrary three-dimensional (3D) penetrometers. The technique is based on that developed in aeronautical engineering for the calculation of incompressible potential flows about arbitrary 3D, non-lifting bodies. It uses a source-density distribution on the surface of the body and solves for the distribution necessary to make the normal component of fluid velocity zero on the boundary. The surface of a 3D body is approximated by a series of plane quadrilaterals, and the integral equation for the source density is replaced by a set of linear algebraic equations which are then solved for the source densities on the quadrilaterals. The displacements and strains are eventually derived based on these source densities. A series of strain-path analyses have been performed for cone and flat dilatometer penetrations. Results show that the soil responses to these two types of penetrometers are fundamentally different.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 95
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    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 575-598 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: There are many expressions proposed for the permeability of isotropic media based on flow channel and pore size distribution concepts, but there are no such expressions for anisotropic media. In this paper an expression for the permeability of an anisotropic medium is proposed, which has been verified in the laboratory.The mechanism behind fluid flow through soil was investigated using microscopic computer simulations to propose an expression for macroscopic permeability. The soil was assumed to be a spatially periodic porous medium, and the Navier-Stokes equation was solved using the FEM with appropriate boundary conditions for several different arrangements of the porous medium. The basic variables influencing flow through soil at the microscopic level were identified as specific surface area, void ratio, particle shape, material heterogeneity and the arrangement of particles in a porous medium. A sensitivity analysis was carried out to obtain an expression for the permeability in terms of the above variables.The corresponding macroscopic variables for the above microscopic variables are average specific surface area, average void ratio, anisotropy, tortuosity due to material heterogeneity, and the arrangement of particles respectively. An expression for the directional permeability is proposed in terms of these variables for the most common occurrence of particles in a porous medium.For the verification of the proposed equation, the permeability values of a fine-grained sand were measured at different void ratios and were compared with those predicted by the proposed equation. The results show that the predicted permeability values from the proposed equation are very close to the measured values.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 96
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    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 675-675 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Type of Medium: Electronic Resource
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  • 97
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    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 629-644 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: The stiffness characteristics of a packing of granules are influenced by the particle interactions at contacts, the void ratio, the co-ordination number and the packing structure. A stress-strain relationship for the packings of spheres is presented. The relationship explicitly includes the contact force-displacement law and the parameters characterizing the packing structure. The initial moduli computed using this relationship are compared with experimental measurements and empirical equations for sands. The theoretical results are also compared with experimental results on packings of glass balls. Closed-form solutions are derived for statistically isotropic packings under initial isotropic stress conditions. Numerical solutions for the stiffness properties are obtained for anisotropic initial stress conditions and anisotropic packing structures.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 98
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    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 677-680 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Type of Medium: Electronic Resource
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  • 99
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 645-664 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: A boundary element approach for time harmonic axisymmetric problems using the complete space point load fundamental solution is presented. The fundamental solution is integrated numerically along the azimuthal co-ordinate of each axisymmetric element. To increase the accuracy of the numerical integration a simple co-ordinate transformation is proposed. The approach is applied to the computation of the dynamic stiffness functions of rigid circular foundations on layered viscoelastic soils. Three different sites are considered: a uniform half-space, a soil layer on a half-space, and a soil consisting of four horizontal layers and a compliant half-space. The numerical results obtained by the proposed approach for surface circular foundations are very close to corresponding published results obtained by different procedures.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 100
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 13 (1989), S. 511-529 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: A simple model for compaction of a sand, that may be useful in various geotechnical applications is presented. The model has been formulated in terms of the cyclic stress and strain amplitudes. The compaction properties of a dry sand are characterized by a common compaction curve described by two coefficients.The second aim of this paper is to show some applications of the theory proposed. The attention has been restricted to the two extreme cases of practical importance, namely to the behaviour of a dry sand (or a saturated sand but in free draining conditions), and to the behaviour of saturated sand in undrained conditions. Some numerical algorithms showing how to deal with those problems are presented and illustrated on the following examples: settlement and pore pressure generation in a soil stratum subjected to an earthquake, settlement of a foundation, pore pressure generation and liquefaction in a sea-bed.The results obtained suggest that the model proposed, as well as a method of dealing with boundary value problems can serve as a useful tool for the analysis of a sandy subsoil subjected to cyclic loadings.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
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