Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2010-2014
  • 1965-1969  (2,082)
  • 1920-1924  (688)
  • Life and Medical Sciences  (2,714)
  • Physical Chemistry  (56)
Source
Material
Years
Year
Keywords
  • 101
    Electronic Resource
    Electronic Resource
    H3-leucine incorporation in antigenically stimulated rat popliteal lymph node cells (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 363-377 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The effect of antigenic stimulation with pertussis and sheep red blood cell antigens was studied in the rat popliteal lymph nodes. H3-leucine was used to assess protein metabolism in the various cell types of the reactive lymph nodes following both primary and secondary stimulation with these antigens. Radioautographs of tissue smears were used to make quantitative and qualitative assessments of the extent of intracellular protein synthesis. In addition, changes in the cellular populations of various lymphoid cell lines were determined utilizing differential cell counts and total cells present in the reacting nodes. These data were used principally to assess the role of the lymphocytic cells in the ontogeny of the immune response.Large and medium lymphocytes responded to antigenic stimuli by increasing intracellular protein synthesis. This newly synthesized protein most likely reflected the requirements of large and medium lymphocytes for growth, division and the production of immunoglobulins. The small lymphocytes, as a group, showed only minimal changes in intracellular protein synthesis following antigenic stimulation.The responses by large and medium lymphocytes and plasma cells were qualitatively similar following primary and secondary stimuli. The differences in these responses appeared to be reflected by the number of cells involved and by the temporal sequence in which the cells appeared.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650306
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 102
    Electronic Resource
    Electronic Resource
    Responses of fatty livers of mice to carbon tetrachlorideSupported by grant HE-07318 and HE-04052 from the National Institutes of Health, U.S.P.H.S. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 391-399 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Female mice of the Taconic Swiss stock were fed one of the three diets described below then injected subcutaneously with 0.035 cm3CCl4/100 gm body weight in a mineral oil solution. One group was fed an adequate commercial laboratory ration, then mice were killed 12, 24 and 48 hours after CCl4; another a cholinedeficient, high-fat, low-protein diet for 14 days, then injected with CCl4, and killed 12, 24 and 48 hours later; and another group, a choline-supplemented (2 gm choline chloride/100 gm diet), high-fat, low-protein diet for 14 days, then injected with CCl4 and killed 24 hours later.In the group fed the normal diet, the polyhalogen produced within 24 hours the expected centrolobular necrosis and glycogen depletion, involving one-third to one-half of the lobular areas. In fatty livers produced by feeding the choline-deficient diet, necrosis at 24 hours post injection was limited in a majority of instances to a zone one or two cells thick immediately surrounding the central vein. Despite this decreased necrosis in fatty livers centrolobular glycogen depletion still involved one-third to one-half of lobules and there was an infiltration of inflammatory cells immediately adjacent to the central vein. The hepatic necrosis at 12 and 48 hours paralleled that in the normal dietary group.Feeding of the choline-supplemented, high-fat, low-protein diet for two weeks produced an extremely limited parenchymal liposis. In such relatively non-fatty livers CCl4 produced hepatic necrosis comparable to that in mice receiving normal diets. The extent of protection from the necrogenic actions of CCl4 was clearly associated with extensive intracytoplasmic liposis of hepatic parenchyma.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650308
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 103
    Electronic Resource
    Electronic Resource
    Histoenzymology of the developing human spinal cord (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 59-65 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In the human fetal spinal cord, enzymatic activity is demonstrated in neurons of the anterior horn a few weeks before it appears in neurons of the posterior horn. This enzymatic activity is present first in the lumbar segment of the spinal cord and with advancing time gradually ascends cephalad. The presence of acetyl-cholinesterase activity in neuronal cytoplasm in the lumbar segment of the spinal cord coincides with the earliest detectable movement in the lower limbs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630107
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 104
    Electronic Resource
    Electronic Resource
    Observations on the distribution of intrarenal nervous tissue (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 81-88 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The distribution of intrarenal nervous tissue in a number of species has been examined using a cholinesterase technique. Particular attention has been paid to the relationships between the renal vessels and their nerves. Nerves were detected alongside the major intrinsic renal vessels and formed nerve networks on the external aspects of the arterial tunicae mediae. In all specimens, afferent arterioles were accompanied by nerves the majority of which terminated near the entrance of cortical afferent arterioles into their respective glomeruli; nerves along juxtamedullary afferent arterioles continued across glomerular hila. Relatively few nerves were demonstrated near cortical efferent arterioles while juxtamedullary efferent vessels possessed a rich innervation. Intramural smooth muscle was identified in juxtamedullary efferent arterioles, aglomerular vessels and arteriolae rectae and these vascular segments were accompanied by nervous tissue. Cholinesterase positive nerves could not be detected in the renal medulla.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630110
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 105
    Electronic Resource
    Electronic Resource
    Editorial (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 133-133 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630201
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 106
    Electronic Resource
    Electronic Resource
    American Association of Anatomists. Eighty-second annual session; Boston University School Of Medicine, Harvard Medical School, University of Massachusetts School of Medicine, Tufts University School Of Medicine, April 1, 2, 3, 4, 1969. Officers, abstracts, demonstrations (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 139-347 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 107
    Electronic Resource
    Electronic Resource
    A correlative investigation of the human rectovaginal septum (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 443-451 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Anatomists and gynecologists have debated the existence of a rectovaginal septum in the human female. In this investigation the connective tissue between the vagina and rectum has been reexamined by both dissection and light microscopy in four specimen types. Specimens studied and compared totaled 143 and represent an age range of from eight fetal weeks to 100 years. Included were specimens from patients with different degrees of parity and both normal and abnormal pelvic visceral support.It has been shown that a definite rectovaginal septum exists in the human female and it is probably the homologue of the male rectovesical septum. The septum is well formed by the fourteenth fetal week and consists of a thin vertical sheet of dense connective tissue which is translucent in the fresh state. In the coronal plane the septum parallels the sacral curvature. It also curves posterolaterally to become fused with the parietal endopelvic fascia. The septum extends inferiorly from the rectouterine peritoneal pouch to the perineal body. It is usually adherent to the posterior aspect of the vaginal connective tissue, capsule. This adherence, together with the difficulty in identifying it histologically may explain why the existence of the rectovaginal septum has been denied.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630307
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 108
    Electronic Resource
    Electronic Resource
    A quantitative study of the blood vessels of the pig's skin and the influence of environmental temperature (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 517-524 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The vascular supply to the skin of pigs was studied in animals perfused with the dye, monastral fast blue. The arrangement of the blood vessels in control animals was in three plexuses, similar to that in other mammals but with the middle plexus poorly developed.A litter of pigs was divided into two groups at the age of 12 days and one group was raised in a warm room and the other in a cold room. The pigs were killed at age three months when the warm room was 35°C and the cold room 5°C. A quantitative evaluation of the blood supply to the skin of the experimental animals revealed that the pigs from the warm room had more blood vessels in the skin than those raised in the cold; the difference was statistically significant (P 〈 0.01). In the case of pigs from a second litter reared at 35°C and 20°C, no significant difference in the number of blood vessels was detected.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630404
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 109
    Electronic Resource
    Electronic Resource
    Spontaneous calcification in hearts of DBA miceSupported by grant (HE 04052) from National Institutes of Health, U. S. Public Health Service. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 153-161 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Onset, frequency and characteristics of the spontaneous calcification which occurs in hearts of mice of the DBA strain have been studied. Calcified myocardial lesions developed as early as 25 days of age. A limited inflammatory response was associated with the fine mineral granules of early lesions. With age, sites of calcium deposition became larger and agranular. There was no evidence of inflammation at such loci and adjacent connective tissue did not increase significantly. In the oldest animals (older than 90 days), fibrous encapsulation of calcified sites was typical. Calcareous epicarditis appeared by 30 days; was minimal (8%) through 90 days, and then rose sharply in incidence (50%) in older animals. Epicardial calcification was restricted to the right ventricle. In general the calcified lesions increased with age and were not related to sex. Incidence of all lesions was 17% by 30 days of age, 80% within 90 days, and 94% in mice older than 90 days.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 110
    Electronic Resource
    Electronic Resource
    Introduction (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 107-108 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650113
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 111
    Electronic Resource
    Electronic Resource
    The The non-thymic origin of lymphocytes (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 109-112 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650114
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 112
    Electronic Resource
    Electronic Resource
    The role of lymphocytes in antibody formation and delayed-type hypersensitivity (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 117-119 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650116
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 113
    Electronic Resource
    Electronic Resource
    Masthead (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650201
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 114
    Electronic Resource
    Electronic Resource
    Ultrastructure of schwann and perineural sheaths at the mouse neuromuscular junction (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 379-390 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Intramuscular nerve branches are covered by a complex of epithelial sheaths which decrease in thickness and complexity as the nerves branch to reach ultimate termination of neuromuscular junctions. The outermost layer (epineurium) of intramuscular nerves is composed of thin processes of fibrocytes lacking basement lamina and associated with parallel bundles of collagen. Internal to this layer are two or three layers of interdigitating perineural cells covered with basement lamina. The innermost layer is frequently incompletely covered by basement lamina within the perineural sheath. Schwann cells covered with basement lamina enclose myelinated and unmyelinated axons.In the region of neuromuscular junctions, the basement lamina of Schwann cell processes merge with the myofiber basement lamina. Thin perineural cell processes form a bell-shaped covering which does not reach the muscle basement lamina. The relationships of myelin to the axon as the terminal axon emerges from the Schwann cell closely resembles the relationships of these structures in nodes of Ranvier.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640401
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 115
    Electronic Resource
    Electronic Resource
    Stratified squamous metaplasia of the uterine epithelium in early androgen-treated rats and its inhibition by light deprivationSupported by grant HD-02937 U. S. P. H. S. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 479-487 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Rats, having been given a single subcutaneous injection of testosterone propionate at four days of age, exhibited polyfollicular ovaries, extensive stratified squamous uterine metaplasia and persistent vaginal cornification (90-95% of the smears contained cornified cells) after adulthood was attained. If early androgentreated rats were blinded at 22 days of age the number of vesicular follicles in the ovaries of adults was greatly diminished, the incidence and extent of stratified squamous metaplastic lesions were suppressed and the number of vaginal smears containing cornified cells was reduced by about 50%. The effects of blinding, however, were negated by pinealectomy illustrating that the suppressive influence of light deprivation on reproduction was mediated by way of the pineal gland.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640406
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 116
    Electronic Resource
    Electronic Resource
    Fine structure of the dermal luminescent organs, photophores, in the fish, Porichthys notatusThis investigation was supported by USPHS predoctoral fellowship number 5-F1-GM-29.402, and in part by USPHS training grant GM 136, and is a portion of the work submitted to the University of Washington Graduate School in partial fulfillment of the requirements for a Ph.D. degree. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 433-461 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Photophores in Porichthys notatus consist of a cellular lens, an underlying area of photogenic tissue and a deep ensheathing reflector. Lens cells exhibit a dense compacted filamentous cytoplasm. Their processes interdigitate and desmosomes exist along their borders. The photogenic tissue, richly supplied by blood vessels, consists of two main cell types: (1) a presumed “photogenic” cell; and (2) a supportive cell. Photogenic cells are characterized by a highly vesiculated cytoplasm and peripheral microvilli. Frequently, they exhibit lamellar membranous whorls. Some whorls display cytoplasmic cores with vesicles. Many of these vesicles communicate via pores with an extracellular channel that envelops the cells. Supportive cells contain cytoplasmic filaments and extend processes around the photogenic cells. Except for isolated desmosomal contact points, a wide extracellular channel intervenes between supportive and photogenic cells. A prominent basal lamina separates supportive cells from the surrounding connective tissue. The strongly birefringent reflector is composed primarily of cells containing guanine crystals. The crystals lie stacked in groups, each membrane-bounded crystal being separated from its neighbor by an intervening layer of cytoplasm. Such an arrangement produces constructive interference and accounts for the high reflectivity of this multilayered structure. Possible relationships of the above structural features and the production of light are discussed.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640404
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 117
    Electronic Resource
    Electronic Resource
    Nuclear and cytoplasmic annulate lamellae in trophoblast giant cells of rat placentaSupported by a Research Grant from the National Institutes of Health (HD-00569) (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 1-13 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Single stranded profiles of nuclear annulate lamellae were identified in giant cells of rat trophoblast from the day when the chorioallantoic placenta first becomes vascularized, viz., day 12 post coitum, until the day before term, viz., day 22. Cytoplasmic annulate lamellae were observed only in giant cells from placentas at day 12. Occasionally cytoplasmic annulate lamellae were found in parallel array. Often the lamellar membranes were continuous with both granular and agranular membranes of endoplasmic reticulum; they closely resembled doubled outer nuclear membrane. Nuclear annulate lamellae resembled doubled inner nuclear membrane; and often the two were found in continuity. In addition, at later gestational ages (17 and 22 days), nuclear lamellae often were related anatomically to the variety of nuclear inclusions which characterize giant trophoblast cells during late pregnancy. A possible relationship of annulate lamellae to the synthesis of DNA, RNA and protein is considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650102
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 118
    Electronic Resource
    Electronic Resource
    A quantitative study of the nucleus of the mesencephalic tract of the trigeminal nerve of the catSupported by U.S.P.H.S. grants GM 1084 and DE 02259. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 79-87 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The number of cells in the mesencephalic nuclei of 38 cats averaged 2015 and ranged from 1237 to 2946. The individual right and left nuclei averaged 980 cells and ranged from 581 to 1489. About 3% of the cells were chromatolytic in the control animals.Various nerves were sectioned and the animals were sacrificed 14 days later. After unilateral section of the nerve to the masseter muscle 18% of the cells in the ipsi- and 9.7% of the cells in the contralateral nuclei were chromatolytic. After simultaneous unilateral section of the nerves to both the masseter and temporalis muscles 3% of the ipsi- and 23% of the cells of the contralateral nuclei were chromatolytic. After unilateral section of the inferior alveolar nerves 13% of the cells of the ipsi- and 9% of the cells of the contralateral nuclei were chromatolytic. After unilateral section of the lingual nerves 9% of the cells of the ipsi- and 7% of the cells of the contralateral nuclei were chromatolytic. After unilateral section of the hypoglossal nerves 12% of the ipsi- and 10% of the cells of the contralateral nuclei were chromatolytic.These results provide anatomical evidence that the axons of the cells of the mesencephalic nuclei are distributed to both the ipsi- and contralateral peripheral nerves. These findings also confirm the presence of such axons in the lingual and inferior alveolar nerves and demonstrate their heretofore unsuspected presence in the hypoglossal nerve.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650109
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 119
    Electronic Resource
    Electronic Resource
    Ovarian morphological and functional changes in reproductively senescent hamstersThis work was supported by Atomic Energy Commission Grant AT45-1-1926 and Training Grant 2T1 GM336 from the N.I.H., U.S.P.H.S.; and is based on part of a dissertation submitted by I.H.T. in partial fulfillment of the requirements for the degree of Doctor of Philosophy in biology at the University of Oregon.Some preliminary results of this study have appeared in abstract form (Thorneycroft, I. H., and A. L. Soderwall 1968 Fed. Proc., 27; 739) (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 349-354 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Ovaries from young and senescent hamsters were examined morphologically on days 8, 12 and 14 of pregnancy to determine if there were any differences between the two age groups. The senescent hamsters had fewer follicles present than the young on all days of gestation. The senescent females' corpora lutea experienced the greatest growth between days 8 to 12, whereas corpora lutea from young animals grew the most between days 12 and 14. Corpora lutea in senescent females did not grow at all between days 12 and 14. The lower number of follicles in senescent females was not due to the lower rate of implantation. Superovulation with PMS revealed that the senescent ovary was refractory.It was concluded that there are quantitative not qualitative differences between ovaries from young and senescent hamsters during pregnancy. The refractory ovary of senescent females could be contributing to pregnancy wastage in this species by secreting less progesterone.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650304
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 120
    Electronic Resource
    Electronic Resource
    Electromyography of genioglossus and geniohyoid muscles during deglutitionSupported by grants from the Medical Research Council and Defence Research Board of Canada to J. V. Basmajian. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 401-409 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: An electromyographic investigation of the activity of the paired genioglossus and geniohyoid muscles of twenty-six human subjects during deglutition revealed a general pattern of muscular activity involving an initial build-up, gradual summation, and tapering of electrical potentials during swallowing of both saliva and water. There is an observable difference in the pattern of swallowing of individuals within a group and among the individual swallows of a single subject. There are longer periods of electrical activity during a saliva swallow than during a water swallow. The type of bolus also seems to affect the pattern of activity in the individual muscles as well as the length of time that they are working. The geniohyoid muscles do not appear to begin their activity with the genioglossus muscles but rather lag behind and they do not appear to be active for as long. Both pairs of muscles appear to remain active during and after the time that the bolus has passed the area of the laryngopharynx. A period of electrical silence occurs prior to the characteristic burst of activity associated with a swallow. This appears to be the result of an active inhibition.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650309
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 121
    Electronic Resource
    Electronic Resource
    The placenta of the four-eyed opossum (philander opossum)Philander opossum)Supported by grant 5 RO1 HD02613 from the National Institute of Child Health and Human Development. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 431-449 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The placental membranes of the four-eyed opossum were studied by light and electron microscopy. The individual fetuses in each uterus were surrounded by amnion, had allantoic sacs of approximately the same size as each fetus, and were situated in a common yolk sac cavity. The extent of the choriovitelline placenta was marked by a prominent sinus terminalis, and at this margin there was a region where the trophoblast cells penetrated folds of the endometrium. Elsewhere the choriovitelline placenta was closely applied to the uterine epithelium along most of its surface, but the microvilli of the two epithelia did not interdigitate. Numerous inclusion bodies were seen in the trophoblast of both the choriovitelline and bilaminar omphalopleure portions of the placenta, but the aggregates were larger in the latter. The endoderm cells of the choriovitelline placenta had extensive endoplasmic reticulum and numerous mitochondria, but did not have conspicuous absorption canaliculi.Placentation in the four-eyed opossum appears to represent a progressive advance over that of the Virginia opossum both in confluence of the yolk sacs of the fetuses and in having a region of penetration of the maternal endometrium by trophoblast.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650311
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 122
    Electronic Resource
    Electronic Resource
    Observations on the fine structure of peripheral nerve myelinSupported by grants AM 0943-03, AM-10628 National Institutes of Health, USPHS; and National Multiple Sclerosis Society 442.This paper has appeared in abstract form (Scallen, T. J. and L. M. Napolitano, 1968. A modified aldehyde fixative for electron microscopy: studies on myelin). Fed. Western Soc. Neurological Sc., Symposium on Neurochemistry, San Diego, Calif. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 1-6 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The incorporation of digitonin 0.2% w/v in cacodylate buffered glutaraldehyde reduces the amount of cholesterol extracted in the dehydrating (lipid extracting) solutions. The fixative enhances membrane structure and results in the preservation of a double minor period in peripheral myelin. The periodicity obtained is in agreement with those derived from x-ray diffraction studies.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630101
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 123
    Electronic Resource
    Electronic Resource
    Light and electron microscopic studies on cellular alterations in the normal bovine placentome (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 17-29 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Placentomes from 12 cows ranging from about 45 days of gestation to full term were studied with light and electron microscopy. The cryptal epithelium and the trophoblast both comprised uninucleate, binucleate and multinucleate cells. The uninucleate cryptal cells were provided with small mitochondria and essentially rough-surfaced endoplasmic reticulum of varying appearance. The uninucleate trophoblastic cells were characterized by an abundance of mitochondria and by morphological evidence of absorption (pinocytosis and phagocytosis). Mitotic figures and sites with cellular degeneration were frequent on the cryptal side but less so on the trophoblastic side. It is concluded that cell turnover is rapid, being confined mainly to the cryptal cells. This is a process in the continuous growth and remodelling of the placentome. There is morphological evidence that the degenerated cells are absorbed by the trophoblast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630103
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 124
    Electronic Resource
    Electronic Resource
    Fenestrated cisternae in the Golgi apparatus of the epididymisSupported by a research grant from the American Cancer Society (E-500), program project HD-002282 of the National Institutes of Health, and Health Sciences Advancement Award (FR-06084) from the National Institutes of Health. The author is the recipient of a Research Career Development Award (1-K3-GM-28.214-01) from the National Institute of General Medical Sciences. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 39-53 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Attention is directed toward the occurrence of fenestrations or pores in Golgi cisternae of rat and mouse epididymis. There is a gradation in the degree of cisternal fenestration within a Golgi complex. Cisternae at the convex pole are highly flattened and contain few pores, but those near the concave side are distended and exhibit a large number of roughly circular fenestrations 300-600 Å in diameter. Cisternae in the middle of a stack often have an unperforated central portion that is surrounded by a fenestrated and expanded peripheral region. The structure of these Golgi complexes is compared with previous descriptions of Golgi cisternae, particularly the fenestrated cisternae reported in plant cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630105
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 125
    Electronic Resource
    Electronic Resource
    Alterations in blood vessels in X-irradiated spinal cords of young rats (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 89-99 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Administration of x-rays (4000 r) to lumbar spinal cords of three-day-old rats caused a loss of neuroglia with an inhibition of myelinogenesis, neuronal damage and necrosis. In contrast, the loss of neuroglia following administration of 2000 r is temporary, with myelinogenesis occurring later than normal. Preliminary observations suggested that differences in vascular responses to these two amounts of x-rays might account for these differing fates of the spinal cords; therefore, this investigation was designed to study further the reactions of the intramedullary vessels.Rats, irradiated when three days of age, were killed 1 to 27 days later. Some were killed by perfusion with Monolite Fast Blue BNVSA Paste, a substance retained in the vessels and readily visualized on microscopic examination. The remaining rats were decapitated, and spinal cords were stained by Gomori's method for alkaline phosphatase. The earliest consistent alteration, a decreased number of vessels, was noted seven days following irradiation with either dose. Rats receiving 4000 r had marked losses of blood vessels, vasodilatation and necrosis by 15 days post-irradiation; whereas, a decreased number of vessels was the only change noted in rats irradiated with 2000 r. Alterations in rats receiving 4000 r remained the same or became more severe throughout the study; spinal cords in rats receiving 2000 r returned to normal. These vascular alterations correlate well with the changes in other spinal cord components described previously by this investigator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630111
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 126
    Electronic Resource
    Electronic Resource
    Ultrastructure of uterine smooth muscle following progesterone or progesterone-estrogen treatmentSupported by USPHS grants AM-08029, HD-01357 avid HD-00606. The investigators are grateful to Dr. Norman Sulkin for making the electron microscope available. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 121-131 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrastructural effect of progesterone, alone and in combination with estrogen, on smooth muscle cells of the rat uterus was studied. Adult, bilaterally ovariectomized rats were untreated (controls) or treated with either progesterone (1 mg), estrogen (1 μg) or both on three consecutive days.Uterine muscle cells appeared larger and myofilaments more abundant in the progesterone-treated rats than in the other groups of animals. Many micropinocytotic vesicles and several dense bodies were present in muscle cells of control, progesterone and estrogen-progesterone-treated rats. In the progestrone-treated group, smooth muscle cells contained little granular endoplasmic reticulum and few ribosomes and glycogen particles, similar to the controls. Mitochondria were more numerous than in the control animals but similar to those seen in the estrogen or estrogen-progesterone-treated rats. Although an accumulation of granular endoplasmic reticulum, free ribosomes, glycogen particles and extensive Golgi complexes occurred in both estrogen and estrogen-progesterone-treated rats, they were more extensive in the former group.The observations indicate that progesterone alters the ultrastructure of the smooth muscle cells but not to the degree observed following estrogen stimulation. It does not markedly inhibit the effect of estrogen on the fine structure of the uterine smooth muscle cells. These observations support previous biochemical studies on glycogen concentration, RNA and protein synthesis in the rat uterus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630114
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 127
    Electronic Resource
    Electronic Resource
    Effects of X-irradiation of immature hamsters on growth and development of gonadsSupported by a grant (GM 14370) of NIH, P. H. S. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 353-358 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Hamsters were x-irradiated at 300 R on 1, 7, 14, 21 or 30 days after birth and sacrificed at the age of 33 days.The body weight, testicular weight and the development of seminiferous tubules were severely affected by irradiation on day 1. The ovarian weight and the number of oocytes were more affected by irradiation on day 7 or 14. Effects of irradiation of immature hamsters on their growth and development of gonads appears to be permanent as irradiation of males on day 1 destroyed all their germ cells by day 33 and irradiation of females on day 7 caused their permanent sterility up to four months of age.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630301
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 128
    Electronic Resource
    Electronic Resource
    Myofibrillogenesis and Z-band differentiation (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 403-425 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Developing myotubes in skeletal muscle tissue from the limbs of larval newts have been examined with respect to the ultrastructure and sequence of events accompanying myofibril formation. A population of filaments having a diameter of 100 Å is found to occur throughout and beyond the period of myofibrillogenesis. This population is in addition to developing actin and myosin filaments and probably does not contribute directly to myofibril formation. Rather it may represent a cytoskeletal network which ultimately becomes principally disposed around and at right angles to older myofibrils at the level of their Z-bands.Assembly of thick and thin filaments into myofibrils seems to occur, in this muscle, predominantly near the periphery of the cell with registration of these components into A-, I-, and Z-bands being accomplished as they assume progressively more internal locations. Z-bands appear to develop by coalescence of Z-bodies which in turn are earlier related to skeins of fine filamentous material which commonly occupy the most peripheral cytoplasm of these and other mesenchymally derived cells. Fine structural details of these skeins, Z-bodies, and Z-bands have been analyzed with regard to the several prevailing concepts of Z-band architecture. An hypothetical sequence for myofibril formation and Z-band differentiation is presented which takes into account several observations and relates them to the looping filament configuration previously proposed for mature Z-band structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630305
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 129
    Electronic Resource
    Electronic Resource
    The fine structure of rabbit platelets fixed in acetaldehydeThis work was supported by grants from the Medical Research Council of Canada (MA 2182) and the Ontario Heart Foundation. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 509-516 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The morphology of platelets fixed in acetaldehyde and postfixed in osmium tetroxide was compared with that of platelets fixed in glutaraldehyde followed by osmium tetroxide. Many platelets became rounded after acetaldhyde fixation. Membranes, granules and mitochondria were well preserved and cytoplasmic microfilaments became apparent. Very dense granules were obvious after acetaldehyde fixation alone and after acetaldehyde/glutaraldehyde/osmium tetroxide triple fixation, but not after acetaldehyde/osmium tetroxide double fixation. Microtubules were never seen. Intracytoplasmic vacuoles assumed exaggerated prominence. The authors relate the alterations in the vacuolar system and changes in platelet shape to a loss of cytoplasmic microtubules. They suggest that the changes are induced, in part by the low temperature of fixation, and in part by the weak fixative action of the aldehyde.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630403
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 130
    Electronic Resource
    Electronic Resource
    The subarachnoid angle: An area of transition in peripheral nerveSupported by HE 09041, United States Public Health Service. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 15-33 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The lateral limit of the subarachnoid space, where nerve roots enter and leave, forms the subarachnoid angle. This is an important site of transition for nerve sheaths. Here the perineurium of peripheral nerve leaves the surface of the nerve and extends between the dura mater and the arachnoid. The perineurium is therefore open-ended with respect to the subarachnoid space. The central perineurial extension is histologically the same as perineurium in some areas but in others forms a layer of hydrated cells without basement membranes. These lie in close apposition with the outermost cells of the arachnoid membrane. At the subarachnoid angle the arachnoid membrane may either reflect onto the root sheath or be attached to it by punctate junctions. The root sheath covers the nerve roots as they pass through the subarachnoid space. It is composed of loosely arranged cells bound by punctate junctions. Its intercellular spaces may contain connective tissue fibrils. A single basement membrane separates it from the endoneurium. The histological structure in the region of the subarachnoid angle is consistent with clinical evidence implicating the endoneurium of nerve trunks as a pathway for the transmission of infection from the periphery to the central nervous system.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640102
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 131
    Electronic Resource
    Electronic Resource
    The significance of intramedullary cancellous bone formation in the repair of bone marrow tissueThese studies were aided with funds from the Atomic Energy Commission contract AT (30-1) 3808 and U. S. Public Health Service grant AM 12444-01 from the National Institute of Arthritis and Metabolic Diseases. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 101-111 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The repair of hemopoietic bone marrow following evacuation of the tibial or femoral cavity of the rat was sequentially studied with the light microscope. A stereotyped train of histologic events occurred. These were capillary invasion of the cavity, appearance of primitive mesenchymal cells, osteoblastic proliferation, cancellous bone formation, development of sinusoids, reappearance of hemopoietic tissue and resorption of cancellous bone. The studies suggest that restoration of marrow sinusoids takes place only in the interstices of cancellous bone. Mechanical disruption of the sinusoidal system is one method of triggering cancellous bone formation. The cancellous bone which appeared after injury was thought to be produced by endosteal osteoblasts and osteoblasts derived from cells residing in normal hemopoietic tissue. Localized radiation of the tibia followed by mechanical disruption of hemopoietic tissue demonstrated that cancellous bone production and the repair process were unimpaired by 1,000 r but were completely blocked by 4,000 r. This would imply that the cell which can differentiate into an osteoblast is resistant to 1,000 r.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640107
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 132
    Electronic Resource
    Electronic Resource
    The ultrastructure of sympathetic ganglia of the lizard Cnemidophorus neomexicanusThis study was performed during the tenure of a post-doctoral fellowship to Gene L. Colborn supported by N.I.H. grant 1-RO1-GM14435-02. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 185-203 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Sympathetic ganglia of six Cnemidophorus neomexicanus lizards were fixed by immersion with glutaraldehyde or a combination of glutaraldehyde and paraformaldehyde. All ganglia were post-fixed in 1% osmium tetroxide and embedded in Epon.Neuronal somata and processes of stellate ganglia were ensheathed typically by capsular cell cytoplasm and membranes; however, parts of some processes were invested only by basement membrane. Axo-somatic, axo-dendritic and axo-axonal synapses were observed. Pre- and post-synaptic processes contained 200 Å neurotubules, 100 Å neurofilaments, 225-500 Å presumptive glycogen granules and occasional multivesicular bodies. Presynaptic endings contained 500-700 Å “clear” vesicles and a few dense-cored vesicles of 600-1100 Å.Aggregates composed of 225-500 Å granules, presumably glycogen, were frequently found in peripheral perikaryal positions in intimate association with lipid droplets. Clusters of particles within somata were also found which resembled ribosomes but were not associated with endoplasmic reticulum or vesicular membranous elements. These clusters, perhaps “areticular Nissl substance,” were associated in some instances with fibrillar material or lattice-like granular structures. Abundant and frequently large lipid droplets were observed in proximity to the ribosomal-like particulate material.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640206
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 133
    Electronic Resource
    Electronic Resource
    Lysosomes in uterine involution: Distribution of acid hydrolases in luminal epitheliumThis investigation was supported by grants HD 00042, National Institute of Child Health and Human Development, and CA 08518 from the National Cancer Institute, National Institutes of Health, U.S. Public Health Service. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 231-251 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The distribution of acid hydrolytic activities in rat uterine epithelial cells during post-partum involution was examined by light and electron microscopic cytochemistry. Acid phosphatase, β-glucuronidase, N-acetyl-β-glucosaminidase and E600-resistant esterase (cathepsin) increased during the period of involution and the electron cytochemical preparations revealed the lysosomal nature of the acid hydrolytic positive particles visualized by light microscopy.The newly formed particles included primary lysosomes, in the form of Golgi vesicles, vacuoles, and secondary lysosomes such as dense bodies and autophagic vacuoles. This apparent increase in lysosomal activity during uterine involution is in agreement with similar patterns observed in the course of tissue regression in general.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640209
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 134
    Electronic Resource
    Electronic Resource
    The effects of fluoride and low calcium on the physical properties of the rat femur (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 305-316 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The effect of fluoride on the physical properties of bone was investigated with the aid of an Instron materials tester. Two groups of weanling female rats, one on an adequate (0.6%) calcium diet and the other on a low (0.1%) diet were given the following dosage levels of fluoride (as NaF) in their deionized drinking water over a fifteen and one-half week period: 3.4 ppm, 10.0 ppm and 45.0 ppm. In the adequate calcium group a significant increase in flexibility in the rat femur was found only at the 45.0 ppm dosage level. This was not offset by a significant decrease in strength. In the low calcium group a similar significant increase in flexibility appeared at the 10.0 ppm dosage level as well as the 45.0 ppm, but a significant decrease in strength at the two dosage levels was observed. These were in direct relation to the amount of fluoride given.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640306
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 135
    Electronic Resource
    Electronic Resource
    Maintenance of gestation in hypophysectomized rats with highly purified pituitary hormones (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 291-303 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Pregnancy was maintained in Long-Evans rats hypophysectomized on day 1 and injected with ovine pituitary gonadotrophins from day 1 through day 11; and also in rats hypophysectomized on day 6 and injected from day 6 through day 11. For successful maintenance until term, no further injections were necessary after day 11. The combination of hormones considered close to optimal was; mammotrophin 2.5 mg; follicle-stimulating hormone 25 μg; and interstitial cell-stimulating hormone 5 μg injected daily, subcutaneously. Histological examination of ovaries after this regimen (on day 12) revealed interstitial and luteal tissue that was considered normal for this stage; and follicles that were in some cases larger than expected and occasionally with theca luteinization. The ovaries of the rats allowed to go to term and untreated after day 11 showed follicular and interstitial tissue that had regressed and well-stimulated corpora lutea. These findings showed no evidence of placental FSH or ICSH-like hormones; but confirmed earlier reports of a rat placental luteotrophic hormone.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640305
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 136
    Electronic Resource
    Electronic Resource
    Light and electron microscopy of the adrenal medulla of macaca mulata monkeyThis work was supported in part by a grant from the Vermont Heart Association. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 317-332 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of the adrenal medulla of Macaca mulata monkey was studied after double fixation with paraformaldehyde and OsO4; other fixations were employed for comparison. Only one cell type was seen. The cytoplasm contained an uneven distribution of chromaffin vesicles which were either spherical or elongated and 0.1-0.3 μ in diameter. There were two principle vesicle categories: dark and compact forms which comprised the majority (about 80%) and lighter, mostly larger, vesicles with a finely granulated appearance. The Golgi apparatus was often seen in relatively clear areas where few other organelles were present. Vesicles, 0.1-0.2 μ in diameter, which stained heterogeneously were also observed. They were few in number and always associated with the Golgi apparatus. The chromaffin cells lay in close proximity, but in no specific relationship, to thin-walled blood vessels. Nerve endings which were partially embraced by Schwann cells were in synaptic relation to the chromaffin cells.These findings are compared with previous observations in other mammals and the nature of the dark and light vesicles is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640307
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 137
    Electronic Resource
    Electronic Resource
    Hair growth cycles in subcutaneous implantsSupported in part by American Cancer Society grant E-392 to Massachusetts General Hospital and USPHS Research grant CA-00592-17 to Brown University. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 333-337 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Skin fragments implanted subcutaneously into syngeneic mice remained viable and showed cyclic hair growth over a period of months. Embryonic skin differentiated into the various layers of epidermis and corium, producing sebaceous glands and hair follicles. Implants from both embryos and newborn displayed normal hair pigmentation with appearance in metanagen of the yellow bands characteristic of the agouti hair for that genotype. Follicles were observed to pass through the various hair growth stages into a resting period and then later to re-enter the growth cycle. There were departures from normal hair growth, however, with some follicular disorganization, especially in the newborn implants, and with areas showing mixed growth stages instead of the follicular synchronization characteristic of the intact mouse.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640308
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 138
    Electronic Resource
    Electronic Resource
    The thymus as a lymphoid organThe work herein reported from this laboratory was supported in part by a grant from the Life Insurance Medical Research Fund _ G-68-11. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 113-115 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650115
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 139
    Electronic Resource
    Electronic Resource
    Masthead (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650301
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 140
    Electronic Resource
    Electronic Resource
    Age changes in the cranial base of the rabbit (Oryctolagus cuniculus) (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 355-361 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The growth changes in the cranial base of the rabbit between one and 20 weeks after birth have been investigated. The basicranial axis and its anterior extension completed some 50% of their growth during this period in contrast to the posterior extension which had completed 70% before one week. The sphenoethmoidal angle underwent no statistically significant changes despite a decrease in the spheno-maxillary angle indicating that the face became disposed below rather than directly anterior to the braincase. The foramino-basal angle decreased progressively during the period of investigation.The pattern of growth in the linear dimensions of the rabbit cranial base is essentially similar to that already established in man and subhuman primates. The angular changes, however, differ from those in primates where the spheno-ethmoidal and foramino-basal angles follow more closely the developmental patterns of the braincase and facial skeleton.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650305
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 141
    Electronic Resource
    Electronic Resource
    Changes in coronary arteries of mice fed a high-fat, low-protein diet followed by a normal dietSupported by grant from the National Institutes of Health, U.S.P.H.S., 5 RO1 HE04052. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 379-389 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Female mice of a Swiss albino stock were fed a high-fat, low-protein, hypolipotropic diet which produces rapid cardiovascular lesions in this stock of mice. Half of the animals were killed after 45 days and the others were placed back on a diet of normal laboratory chow and killed after one, two and three weeks of refeeding.In animals killed after receiving the experimental diet for 45 days small, focal deposits of hyalin in media of large coronary arteries of the right ventricle was the major change.During the first week of recovery (fed a normal diet) the incidence and severity of arterial lesions increased and within individual hearts arteries of all sizes and in both atria and both ventricles were involved. Following hyalinization an acute arteritis developed that involved all layers of the arterial wall and extended into the perivascular space.After two and three weeks recovery the coronary arteries were characterized by a periarterial fibrosis and by a decrease or absence of the leucocytic reaction. A subendothelial hyperplasia of smooth muscle, arranged longitudinally, was accompanied by an increase in reticular and collagenous fibers. Circular smooth muscle in the media was also hyperplastic.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650307
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 142
    Electronic Resource
    Electronic Resource
    Temporal and cytological aspects of fertilization and early development in the guinea pig, Cavia porcellus (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 411-429 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A study was made of 174 eggs recovered from 58 guinea pigs killed between the first and sixth days after mating, and the cytological details from the stage of sperm penetration to the pre-implantation blastocyst described. Eighty-nine percent of the expected number of eggs were recovered, and 97% of these were fertilized. Embryonic development proceeded from pronuclear and 2-cell eggs on day 1 to pre-implantation blastocysts on day 6, the duration of each of the early cleavage stages being of approximately 24 hours. No progressive loss of embryos was found over this period, all the eggs recovered on days 4, 5 and 6 being regarded as developing normally. Passage of embryos from the Fallopian tubes to the uterus commenced on the afternoon of day 3, and the majority of embryos entered the uterus shortly after this time at the stage of 8- to 16-cells. The tail of the fertilizing spermatozoon was detected in the cytoplasm of all eggs examined on day 1, in most of those examined on day 2, and frequently persisted up to the 8-cell stage. Three dispermic eggs, each containing two distinct cytoplasmic sperm tails, were found: one of these was at the pronuclear stage, the other two being considered of 4- and 6-cells respectively. Properties of adhesiveness were shown by blastocysts recovered shortly before implantation on day 6, but the characteristic “zona processes” were not seen.
    Additional Material: 7 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650310
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 143
    Electronic Resource
    Electronic Resource
    Reconstitution of the external granular layer of the cerebellar cortex in infant rats after low-level X-irradiation (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 453-471 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The heads of three-day old rats were irradiated with a single dose of 200 r x-ray and the animals were killed afterwards at intervals ranging from ten minutes to five days. Necrosis in the external granular layer of the cerebellum was evident by the fourth hour and the pyknotic cells increased in number up to 12 hours after irradiation. Between 24 to 48 hours all the pyknotic cells disappeared and the width of the layer was drastically reduced. By the third day after irradiation the external granular layer began to increase in width, and by the fourth day it was indistinguishable from normal. In adults of this group the cerebellum appeared structurally normal. In another experiment the cerebellum of rats was exposed from birth onward to 200 r on five successive days. In the animals killed immediately or one day after the last radiation session the external granular layer was totally or subtotally eradicated. In the animals surviving for four days the external granular layer reappeared over many regions of the cerebellum, and by the sixth day after irradiation it was present over its entire surface. In the latter group in animals that survived to 30 and 90 days of age the cerebellum contained a large, though subnormal, population of granule cells, indicating that the reconstituted cells were able to differentiate. These results suggested that the proliferative matrix of the postnatally developing cerebellum may be endowed with regenerative capacity.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630308
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 144
    Electronic Resource
    Electronic Resource
    Effect of age on alkaline phosphomonoesterase activity in the adrenals of male miceThis research was supported by National Institutes of Health grant NB-03021. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 473-482 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This investigation was undertaken to examine the effects of aging on alkaline phosphomonoesterase (Alk Pase) activity in the adrenals of a highly inbred strain of C57BL/10 male mice. A total of 140 male mice were assigned to seven main groups and sacrificed at 1, 4, 8, 12, 16, 20 and 24 months of age for biochemical and morphologic evaluations of adrenal Alk Pase activity. The biochemical findings indicated that while aging may result in a decrease of serum and liver Alk Pase activity, enzyme activity in the adrenals of male mice increases to a maximum level at approximately eight months of age and subsequently decreases at each successive age level. The histochemical findings revealed that the highest concentrations of enzyme activity occurred in the fascicular and reticular zones of sexually mature male mice. There were no major variations in zonal distribution with advancing age. Electron microscopy showed Alk Pase activity along membranes of cortical cells and within the subendothelial space.The progressive increase in Alk Pase enzyme activity up to eight months of age, and the subsequent fall in activity during senescence as well as its absence in the adrenals of female mice provides further support for a role of androgen in mobilizing cortical alkaline phosphomonoesterase activity.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630309
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 145
    Electronic Resource
    Electronic Resource
    A comparison of alveolar macrophages and pulmonary surfactant(?) Obtained from the lungs of human smokers and nonsmokers by endobronchial lavageSupported by research grants from NIH (HE 09491-03, HE 12571-01 and I-ROI-GM-14435-02) and from the Council for Tobacco Research U.S.A. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 497-507 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Endobronchial lavage was performed on eight smokers and eight nonsmokers. Centrifugation of lavage fluid produces a sediment consisting of two layers, a lower compact brown layer containing cells and an upper flocculent white layer. The brown layers from the smokers were greater in volume than those from the nonsmokers. Macrophages constituted about 93% of the cells from the smokers and about 63% of the cells from the nonsmokers. These data suggest that more free macrophages occur in the lungs of smokers than nonsmokers. In addition, many of the macrophages obtained from the smokers were filled with cytoplasmic inclusions. The volumes of white layers from the smokers were smaller than those from the non-smokers. One white layer obtained from a nonsmoker was examined in a Wilhelmy balance and proved to be surface-active. This may suggest that surface-active material, pulmonary surfactant, is reduced in lavage fluids from smokers.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630402
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 146
    Electronic Resource
    Electronic Resource
    Deciduomal response of the golden hamster uterus (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 563-573 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The deciduomal response to uterine trauma in pesudopregnant hamsters has been studied. Trauma was effected in one uterine horn by leaving a sterile silk thread in the lumen, pulling a thread through the lumen, injecting oil or air into the lumen or crushing the horn with a hemostat. At autopsy the traumatized and untraumatized horns were weighed separately and examined histologically for a deciduomal reaction. The day of greatest uterine sensitivity was found to be day 4 of pseudopregnancy, and maximal deciduomal growth (mean uterine weight ± S.E. = 2582 ± 279 mg) occurred by day 8. No significant further increase in uterine weight was seen by day 9, and by day 10 separation of the deciduoma from the myometrium had begun. Leaving a thread in the uterine lumen produced a significantly greater uterine weight by day 8 than with any other stimulus, but good deciduomal responses (uterine weights of 1679 ± 245, 1255 ± 156 and 1192 ± 219 mg) were induced by oil injection, pulling a thead through the uterus and crushing the uterus respectively. A poor reponse was produced by air injection. At no particular time during day 4 of pseudopregnancy was it possible to demonstrate a peak of uterine sensitivity using as a traumatic stimulus either oil injection or pulling a thread through the lumen. In this respect hamsters differ from both rats and mice, which have well defined peaks of maximal uterine sensitivity.
    Additional Material: 6 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630408
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 147
    Electronic Resource
    Electronic Resource
    Fine structure of the resorptive cells in the teeth of frogsThis investigation was supported by Public Health Service Research grant DE 02201 from the National Institute of Dental Research. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 1-13 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Teeth undergoing resorption were dissected from the maxillae of frogs and prepared for electron microscopy using standard methods and methods designed to minimize demineralization. The resorptive cells overlapped one another, forming palisades. A central ruffled border was surrounded by a relatively structureless cytoplasmic “seal.” Crystals of mineral were present in the folds of the ruffled borders, and demineralized collagen fibrils were seen in the adjacent matrix in sections treated to prevent demineralization. The surfaces of the cells opposite the ruffled borders displayed numerous small villi.The cytoplasm of the resorptive cells contained a variety of lysosomes in various stages of development, mitochondria, scattered vesicles of endoplasmic reticulum and free ribosomes. Well developed Golgi zones were frequently seen, and occasional sections passed through centrioles. Two centrioles were commonly seen in such sections, but never more. Occasional patches of cytoplasm contained mitochondria and rough-surfaced endoplasmic reticulum, resembling “blast” cell cytoplasm.We concluded that the resorptive cells of several mineralized tissues of various vertebrates are morphologically, indistinguishable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640101
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 148
    Electronic Resource
    Electronic Resource
    Eruption pathway formation in the presence of experimental tooth impaction in puppiesSupported by USPHS grant 1 SO 1 FR 5417-04-5. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 67-77 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Eruption of permanent premolars in puppies was studied by implanting stainless steel wires through the mandible to stop eruptive movement well before the teeth were to appear in the oral cavity. Histologic and radiologic comparisons of operated with normal (unoperated) sides disclosed that the eruptive pathway forms for the impacted teeth although their eruptive movements were effectively prevented. This clearly shows that the mechanism of eruption pathway formation is not dependent upon direct and continual pressure on the bone from the erupting teeth. The genesis of pathway formation appeared to be the same for the impacted teeth as for the controls i.e., through continued ostetoclasis in the margin of the stalk of the dental follicle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640105
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 149
    Electronic Resource
    Electronic Resource
    Electron microscope observations on the shell gland mucosa of calcium-deficient hens (Gallus domesticus) (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 127-139 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Calcium-deprivation of three weeks duration causes marked degenerative changes in the shell gland mucosa of the laying hen. The height of the columnar epithelium decreases, but the secretory granules in the columnar epithelial cells and the cilia on the apical cells of the columnar epithelium are preserved. The tubular glands decrease in size and number. The microvilli surrounding the tubular gland lumen disappear. The cytoplasm of the tubular gland cell contains autophagic vacuoles (cytolysomes) and large pigment accumulations, presumably lipofuscin. The changes are due to dietary calcium deficiency, apparently mediated by decreased sex steroid secretion and decreased stimulation of the oviduct. These changes are totally reversible, since the fine structure of the shell gland mucosa of calcium-deprived hens returned to a normal laying diet does not show any signs of degeneration and is identical with the fine structure of the shell gland mucosa of the laying control birds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640201
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 150
    Electronic Resource
    Electronic Resource
    The cilium on mammalian vestibular hair cellsResearch supported in part by USPHS grant RG-06729 and in part by the William F. Milton Fund of Harvard University. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 253-258 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The mammalian vestibular cilium is described. It is shown to be comprised of nine dense outer fibers and an intermittent central density; this stands in contradistinction to vestibular cilia of non-mammalian species that have been shown to be comprised of nine outer doublet tubules surrounding two central tubules. The possible functional meaning of these observations is discussed.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640301
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 151
    Electronic Resource
    Electronic Resource
    Uniformity of structural characteristics throughout the length of skeletal muscle fibersContribution no. 50, Neuromuscular Laboratory, Department of Physiological Sciences, College of Veterinary Medicine KSAES, KSU, Manhattan.Supported by USPHS, NIH grant NB-05786. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 219-229 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Fresh-frozen, serial cross-sections of the transversus abdominis muscle of four mature chickens (98 fibers) were examined to determine structural and histochemical characteristics throughout the entire length of skeletal muscle fibers. Fiber diameter and nicotinamide adenine dinucleotide diaphorase (NAD-D) and myosin adenosine triphosphatase (ATPase) activities were used as criteria to classify fibers as Type I or II. Measurements were made at 10 to 22 locations along the length of the fibers. An unimodal distribution of mean fiber diameters ranging from 48 μ to 86 μ was found. Fibers did not appear larger in the belly of the muscle than near the ends. Although small fluctuations in fiber diameter occurred through the length of a fiber, large and small fibers tended to remain relatively large or small at each location. NAD-D activity was either consistently high or low throughout the length of a fiber. Likewise, myosin ATPase activity was either high or low for an entire fiber. It is concluded that skeletal muscle fibers maintain rather uniform structural and histochemical characteristics along their entire length.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640208
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 152
    Electronic Resource
    Electronic Resource
    The role of the thymus in development of lympho-hemopoietic tissues. The effect of thymectomy on development of blood cells, bone-marrow, spleen, and lymph nodesAided by grants from The National Foundation, USPHS (AI-08677, NB-02042, AI-00292), American Heart Association and American Cancer Society. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 267-281 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The effect of thymectomy at different ages in C3H mice on development of circulating leukocytes and cells of marrow, spleen and lymph nodes has been analyzed. Regardless of the age at which thymectomy is performed depression of numbers of circulating lymphocytes is produced. Thymectomy at birth did not affect significantly the relative number of lymphocytes in the marrow during the first few weeks of life, later they fell to low levels. Thymectomy at four weeks was followed by prompt reduction in relative numbers of lymphocytes in the marrow.After reaching six weeks of age, neonatally thymectomized mice showed a high proportion of monocytes in the marrow. Neonatal thymectomy and thymectomy at two weeks of age reduced the number of eosinophils in the marrow.Neonatal thymectomy inhibited development of lymphocytes in the spleen, whereas thymectomy later in life produced only transient depression of lymphocytes in this organ. In addition, neontal thymectomy decreased the relative numbers of small lymphocytes in the lymph nodes. This was associated with drastic depletion of lymphocytes in the deep cortical regions of the nodes.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640303
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 153
    Electronic Resource
    Electronic Resource
    The pelvis of the free-tailed bat: Sexual dimorphism and pregnancy changesThis investigation was supported in whole by Public Health Service Research grant AM 09499-14 from the National Institute of Arthritis and Metabolic Diseases. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 349-357 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: There are constant morphological differences between the bony pelves of adult males and females that constitute a sexual dimorphism. A convexity along the caudal border of the ischiopubic ramus and a bony projection bordering the pubic joint are present only in the male. The pubic joint in the male is a typical symphysis, whereas in the female it consists of an interpubic ligament interconnecting the coxal bones. The ligament contains an abundance of elastic fibers interspersed among collagenous fibers. The disparity between the size of the pelvic birth canal of the pregnant bat and the single full-term fetus is so great that during parturition the interpubic ligament stretches to more than 15 times its original length.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640310
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 154
    Electronic Resource
    Electronic Resource
    The fine structure of autonomic nerves after vital staining with methylene blue (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 359-377 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Autonomic nerves in the rat, mouse, guinea-pig and cat were vitally stained with methylene blue and examined electron-microscopically after fixation in potassium permanganate. Dense patches in the axoplasm and swelling of mitochondria were found in the stained axons. By controlling the pH and saturating with oxygen, only cholinergic axons were stained at pH 6.5-7.0 whereas at pH 5.0-5.3 both cholinergic and adrenergic axons stained. Similar results were obtained by immersion in a bath at controlled temperature as with close arterial perfusion of dye into pelvic viscera. The intermediate pH at which adrenergic axons begin to stain could not be determined. However, as a means of identifying cholinergic axons, particularly those sectioned at a level where no agranular vesicles occur, M B staining is unreliable because not all cholinergic axons respond. In sympathectomized rat iris lacking adrenergic axons altogether, some of the persisting cholinergic axons remained unstained. Experiments with M B thiocyanate and M B chloride in phosphate-citrate or succinate-HCl buffer indicated that purity of dyestuff was less important than pH control. Methods for electron-microscopical demonstration of acetylcholinesterase are more useful for distinguishing cholinergic axons especially if adrenergic nerve vesicles are I reserved in the same preparation by the initial fixation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640311
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 155
    Electronic Resource
    Electronic Resource
    The paranucleolar structure, accessory body of cajal, sex chromatin, and related structures in nuclei of rat trigeminal neurons: A cytochemical and ultrastructural studySupported by grants 10956 and 11028 from National Institutes of Health and the National Cystic Fibrosis Research Foundation. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 403-431 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Comparative light and electron microscopic study of nuclei in rat trigeminal neurons identified two structures which are the ultrastructural equivalent of the paranucloelar structure and the accessory body of Cajal, two nucleoplasmic structures previously demonstrated in other neurons by light microscope silver staining methods. Ultrastructural evidence indicates that the dense component of the nucleolus is converted into the paranucleolar structure, which then detaches from the nucleolar surface to lie free in the nucleoplasm as the accessory body of Cajal. The cytochemistry, ultrastructure, and antimonate reactivity of the paranucleolar structure and accessory body were identical. Both structures lacked cytochemically demonstrable DNA, RNA, or basic protein.The neuronal nuclei also contained Feulgen-positive sex chromatin bodies that adhered to the nucleolus, the nuclear membrane, or to both of these structures in specimens of female but not male rats. The ultrastructure and antimonate reactivity of these bodies closely resembled that of heterochromatin clumps but differed markedly from that of the paranucleolar structures and accessory bodies.Additional structures characterized ultrastructurally included patches, granular bodies, and flakes. These structures, like the paranucleolar structure and the accessory body of Cajal, are apparently unique to nuclei of neurons. Cytochemical methods showed that the patches contained basic protein but no nucleic acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640403
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 156
    Electronic Resource
    Electronic Resource
    Photophores of Porichthys notatus: Ultrastructure of innervationThis investigation was supported by USPHS predoctoral fellowship number 5-F1-GM-29,402 and is a portion of the work submitted to the University of Washington Graduate School in partial fulfillment of the requirements for a Ph.D. degree. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 463-477 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Photophores in Porichthys notatus are bioluminescent organs composed of a lens, photogenic tissue, and an underlying reflector. Nerves penetrate through the reflector and branch, free of their Schwann cells, among the photogenic tissue elements. The tortuous pathways of axons have been followed by electron microscopical serial sections. After giving off occasional terminal branches, the axons continue into pockets of connective tissue which penetrate among the photogenic, supportive, and lens cells. There they form tuft-like clusters of nerve endings, some of which contain dense-cored vesicles. None of these endings was seen to penetrate the basal lamina and make direct intercellular contact with either a supportive cell or a photogenic cell. From these observations, it is concluded that the nerves end outside of the basal lamina surrounding photogenic, supportive, and lens cells. Adhesion sites, which may indicate chemical synaptic contact, were occasionally observed among these neural components.The photophores of the California Porichthys notatus often bioluminesce following intraperitoneal injection of the fish with epinephrine. It therefore appears from experimental, anatomical and fine structural evidence, that these luminescent organs are innervated and controlled by the sympathetic nervous system.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640405
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 157
    Electronic Resource
    Electronic Resource
    Masthead (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650101
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 158
    Electronic Resource
    Electronic Resource
    Ultrastructure of the placenta and fetal membranes of the dog I. The placental labyrinthSupported by national institutes of health grant HD-00277. A part of this material was presented at the annual meetings of the American Association of Anatomists (Anderson, '66) (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 15-35 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrastucture of the canine placental labyrinth has been studied at 40 to 60 days of gestation. Cytotrophoblasts persist in an undifferentiated state throughout gestation, with numerous polyribosomes and little rough endoplasmic reticulum, with expanded cisterns containing flocculent precipitate. Fetal capillaries progressively invade the syncytium, without, however, penetrating the basal lamina. Maternal decidual cells are reported here for the first time in this species. The maternal endothelium is considerably hypertrophied, with many profiles of membranous organelles; but there is consideriable thinning of this endothelium between 50 and 60 days. The interstitial membrane intervenes between trophoblast and maternal endothelium, often forming the thickest part of te barrier at 60 days. the definitive endotheliochorial condition is confirmed; and the thinnest barrier is about 1 μ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650103
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 159
    Electronic Resource
    Electronic Resource
    Structural luteolysis of induced corpora lutea in “androgen-sterilized” ratsJournal paper no. 3487, Purdue University Agricultural Experiment Station. Supported in part by grant HD-2423 from the U. S. Public Health Service. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 55-60 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Five-day-old female rats were made anovulatory by injection of 50 μg testosterone propionate. When the animals were at least 120 days old, corpora lutea (CL) were induced by injection of human chorionic gonadotrophin (HCG). Various treatments were initiated 15 days after HCG and the morphological regression of induced CL was examined 30 days after HCG. Structural luteolysis was very slight in control animals, suggesting that prolactin secretion was minimal. Exogenous prolactin hastened the rate of luteal regression. Daily injections of estradiol or reserpine also caused rapid structural luteolysis. Destruction of the arcuate nucleus of the hypothalamus also induced morphological regression at a more rapid rate than in controls. In conclusion, exogenous prolactin or three different treatments known to promote secretion of endogenous prolactin accelerated the rate of luteal regression in induced CL.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650106
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 160
    Electronic Resource
    Electronic Resource
    Insertions of intrafusal fibers in muscle spindles of the cat and other mammalsSupported by NSF grant GB-6936 and USPHS grant NB 03019. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 391-401 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The manner of insertion of intrafusal (IF) fibers of muscle spindles has been studied in serial histological sections of spindles from hindlimb muscle of the cat, opossum, mouse, rat, bat and gibbon. Four basic types of IF terminations in relation to the capsule were recognized: (A) direct insertion into the capsule; (B) strong lateral attachments to the capsule, though the fiber may continue beyond the capsule; (C) termination in the connective tissue beyond the limits of the capsule; (D) free extension of the fiber beyond the capsule. Bag fibers in all species generally extended beyond the capsule. The pattern of chain fiber insertion, however, varied with the species. Most rat spindles, for example, followed the D pattern, those in the cat pattern A, and the gibbon chiefly A and B. The bearing of these findings upon a postulated mechanism by which spindles may detect intramuscular pressures, as changes in length, is discussed.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640402
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 161
    Electronic Resource
    Electronic Resource
    Rauber-kopsch: Lehrbuch und atlas der anatomie des menschen. Edited by Wolfgang Bargmann, Helmut Leohardt and Gian Töndury. 20th Edition 1968 Vol. I: Bewegungsapparat (bones, joints, muscles) by Gian Tondury. Xii + 569 pages, 675 figures. Georg Thieme Verlag, Stuttgart (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 489-490 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640407
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 162
    Electronic Resource
    Electronic Resource
    Book received (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 490-491 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640408
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 163
    Electronic Resource
    Electronic Resource
    The distribution of valves in rat kidney arteriesSupported in part by grants HE-5690 and AM-08746 from the National Institutes of Health. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 37-39 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Serial sections of rat kidneys were studied for the presence of valves. Intimal valves were found in interlobular arteries at sites where arteriolar branches went directly to juxtamedullary glomeruli. Arteriolar branches to glomeruli which are not juxtamedullary glomeruli did not possess valves at their origins. This location suggests that these valves may be important as regulators of blood flow to the vasa recta spuria which supply the medulla.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650104
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 164
    Electronic Resource
    Electronic Resource
    The ultrastructure of granulosa cells in the newborn rabbit ovary (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 67-77 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In the first two weeks of life the pregranulosa cells located in the sex cords of the rabbit ovary become increasingly flattened and elongated to isolate and encircle individual oocytes. During this period there is a marked increase in the amount of intracytoplasmic lipid in the pregranulosa cells. The lipid is associated in clusters with adjacent mitochondria. The accumulation of lipid deposits within the pregranulosa cells suggests that the newborn rabbit ovary may be capable of steroid synthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650108
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 165
    Electronic Resource
    Electronic Resource
    The human skull. A cultural history. By Folke Henschen, translated from Swedish by Stanley Thomas, with an Introduction by Kenneth P. Oakley. 168 pages, 22 figures, and 76 plates. $7.95. Frederick A. Praeger, Publisher, New York (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 103-104 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650111
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 166
    Electronic Resource
    Electronic Resource
    The occurrence of tubular intramitochondrial inclusions in the post-mortem zona fasciculata of the rat adrenalSupported by grant HD-02494 from the National Institutes of Health, U.S.P.H.S., D.H.E.W. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 41-54 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Adult male albino rats are decapitated and the mitochondria in one adrenal gland are examined at increasing post-mortem time intervals in the electron microscope. The contralateral adrenal gland is excised rapidly, immersed in aldehyde fixative, diced, and used as the control. As early as 15 minutes postmortem, tightly packed sheaves of tubules (each tubule measuring 140 AR in outside diameter) appear as inclusions in the matrix of mitochondria within the zona fasciculata. These inclusions occur in increasing numbers of mitochondria during the first hour postmortem, until 10-25% of the mitochondria examined contain at least one sheaf of tubules. Observations at two and three hours post-mortem reveal no significant increase in inclusion-containing mitochondria. At these late time intervals additional post-mortem alterations are evident: (1) a decrease in mitochondrial matrix density; (2) swelling of mitochondrial cristae; and (3) vesiculation of the smooth reticulum. Kjaerheim ('67), Wheatley ('68), and Magalhaes and Magalhaes ('68) have described tubular inclusions in the matrix of “normal” rat adrenal mitochondria which are identical to the post-mortem inclusions described in this study. The presence of such inclusions in control mitochondria has been observed by the author on one occasion: within a degenerate mitochondrion enclosed inside a cytoplasmic membrane-limited vacuole. The possible significance of this post-mortem mitochondrial alteration in the rat adrenal cortex is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650105
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 167
    Electronic Resource
    Electronic Resource
    Histochemical observation on the phosphatase activities of the differentiating taste bud (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 61-66 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Adenosine triphosphatase, alkaline phosphatase and acid phosphatase activities of the developing taste buds were observed histochemically in the rat circumvallate papilla.Adenosine triphosphatase activity was already demonstrable in a cluster of cells in the epithelium of the papilla on the first day of birth, when taste buds could not yet be morphologically identified. The cells with the activity are certainly considered as the differentiating taste bud cells. These cells took the form of a bud similar to the adult one about the fourth day of life.Alkaline phosphatase activity was demonstrated first on the superficial cell layers of the epithelium of its apical surface as well as on that of the epithelium in the gutter of circumvallate papilla just after birth. The activity in the gutter then rapidly increased, while the activity of the apical surface abruptly decreased and disappeared on the second day of life.Acid phosphatase was demonstrable only in some cells of the taste bud on the fourth day of life. The final pattern of the activity, which is found in the supranuclear cytoplasm of taste bud cells, was established after the eighth day of life.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650107
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 168
    Electronic Resource
    Electronic Resource
    Symposium on: The life history of lymphocytes1 held April, 1969 at the eighty-second annual meeting of the American Association of Anatomists in Boston, MassachusettsThe contributions of the Chairman and the investigative efforts of Everett, Caffrey and Rieke, which are referred to in this Symposium, have been supported by USPHS Research Grants AI07509, GM06309 and AEC Contract AT (45-1)1377. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 105-105 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650112
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 169
    Electronic Resource
    Electronic Resource
    The role of the lymphocyte in transplantation immunity (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 121-124 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650117
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 170
    Electronic Resource
    Electronic Resource
    Closing remarks (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 125-125 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650118
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 171
    Electronic Resource
    Electronic Resource
    A study of the cardiac innervation in domestic animals: Cattle (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 141-151 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The cardiac innervation of cattle was morphologically dissected and described. Descriptions of the ganglia of origin as well as the course and distribution are presented. Sympathetic nerves arose from the thoracic and cervicothoracic ganglia, but unlike those of the horse, dog and cat did not arise from the more cranial situated cervical ganglia. Most left thoracic and some cervicothoracic cardiac nerves passed through a cardiac ganglion of the left intervascular triangle before being distributed to the heart. Parasympathetic cardiac innervation arose from the vagi, both cranial and caudal to the origin of the recurrent laryngeal nerve, and from the recurrent laryngeal nerves themselves. Left heart nerves primarily supplied the area along the coronary groove caudally and on the right side. This included the area of the coronary sinus and atrioventricular node. Left cardiac nerves also extended along the right coronary artery. Both left and right cardiac nerves passed to the cardiac plexus and also along the descending and circumflex branches of the left coronary artery on the left side. Right cardiac nerves extended primarily between the venae cavae or between the caudal vena cava and left atrium to the area of the sinoatrial node but also into the area of the coronary sinus and atrioventricular node.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 172
    Electronic Resource
    Electronic Resource
    The double nature of the intermediate dense line in peripheral nerve myelinSupported by USPHS grant RG-06729, by the William F. Milton Fund of Harvard University and by USPHS grant GM11380-05. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 7-15 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In myelin of peripheral nerves it is shown that the intermediate dense line is split after aldehyde fixation (with uranium post-treatment) with a 20 Å gap intervening between the apposed outer leaflets of the Schwann cell membrane. This gap is permeable to colloidal lanthanum, which indicates that it is continuous with the extracellular space. Our observations are discussed in light of data of other investigators.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630102
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 173
    Electronic Resource
    Electronic Resource
    Determination of the red blood cell count and haemoglobin content of urodele blood (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 55-57 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Red blood cell count and haemoglobin content for blood of normal adult salamanders, Taricha granulosa, are presented. The RBC count is some 4 × 104/mm3 blood and the haemoglobin level some 4.5 gm/100 ml blood. Some evidence suggesting transient changes in these levels for a brief period immediately following hibernation is discussed.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630106
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 174
    Electronic Resource
    Electronic Resource
    The presence of fenestrated capillaries in the papillary layer of the enamel organ (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 71-79 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The capillary network of the papillary layer of the enamel organ was studied with the electron microscope. Mandibular incisor teeth of ten-day old Swiss albino mice were fixed in formaldehyde-glutaraldehyde, postfixed in osmium tetroxide and prestained with 0.5% uranyl acetate prior to being embedded in Epon. Examination of ultrathin sections revealed the presence of fenestrations approximately 500 Å to 700 Å in diameter within the most attenuated regions of the capillary walls. In most instances the fenestrations appeared to be closed by diaphragms usually consisting of a thin membrane with a thicker centrally located button of electron opaque material.The presence of fenestrated capillaries within the papillary region of the enamel organ lends further support to the concept that papillary cells are engaged in transport functions during the maturation of enamel.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630109
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 175
    Electronic Resource
    Electronic Resource
    Changes in the fine structure of satellite cells surrounding chromatolytic neurons (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 101-109 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of satellite cells surrounding neurons in the superior cervical ganglia of the rabbit is described. These observations form a basis for the interpretation of fine structural changes which occur in the satellite cells after post-ganglionic section. Early changes consist of an increased number of micropinocytotic vesicles indicating an enhanced uptake of extracellular materials. The mitochondria increase in length and lie close to the plasma membranes, reflecting the increased energy requirement of these cells. Many develop intramitochondrial granules which may be concerned with the transport of water or ions. Later, at the height of chromatolysis, the satellite cells increase their quantity of granular reticulum and many possess agranular sub-surface cisternae whose function may be to direct material synthesised in the satellite cells to the nerve cell surface. Individual layers of satellite cell cytoplasm may slide over one another to accommodate the increased size of the neurons during chromatolysis. The satellite cell processes appear thickened and contain large numbers of fine filaments which may be formed by the breakdown of microtubules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630112
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 176
    Electronic Resource
    Electronic Resource
    Galen on the usefulness of the parts of the body. Translated from the Greek with an Introduction and Commentary. By Margaret Talladge May. 1968. xv + 802 pages in 2 volumes. $25.00. Cornell University Press, Ithaca, New York (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 135-137 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630202
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 177
    Electronic Resource
    Electronic Resource
    Ovarian activity in the intact or hypophysectomized pregnant mouse (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 359-372 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Various parameters of ovarian activity were determined for the intact or hypophysectomized pregnant mouse, as a baseline to establish the nature of luteotropic hormones in this species.Seventeen per cent of White Swiss mice with a vaginal plug were not pregnant at subsequent stages of gestation. The greatest number of failures occurred between days 12 and 15 of pregnancy, coinciding with the temporary absence of antral follicles and regressive changes in the vaginal epithelium. This suggests that there is a period of transient hormonal imbalance before full placental function is established, which is responsible at this time for the peak in embryonic mortality.Two periods of luteal growth were apparent between days 1 and 4 and 10 to 14 of pregnancy. The first histologic evidence of luteal regression occurred at day 16, correlating with renewed squamous cell proliferation of the vaginal mucosa.There were no significant differences in the number of ova shed on day 1 of pregnancy (11.0 ∓ 0.5 ova) and the subsequent number of embryonic swellings at any stage. Gestation in intact pregnant mice lasted 18 days (n = 2) or 19 days (n = 36). The number of young counted late on day 1 post partum (9.1 ± 0.5) was significantly less than the number of embryonic swellings as a result of maternal cannibalism.Hypophysectomy on day 1 of pregnancy led to rapid histologic degeneration of the corpus luteum. In this feature, the mouse resembled the hamster rather than the rat. Day 10 of pregnancy represented the earliest time at which, at least in some animals the pituitary could be removed and pregnancy continue. Following hypophysectomy from day 11 on, luteal activity, continuation of pregnancy, fetal and placental weight and vaginal histology were comparable to intact, pregnant mice. This is similar to the hypophysectomized rat in the latter half of pregnancy but differs from the situation in the hamster.On the basis of the present findings and results in the following paper, it appears likely that the mouse placenta, in addition to secreting a prolactin-like hormone, also produces other gonadotropins.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630302
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 178
    Electronic Resource
    Electronic Resource
    Electron microscopic studies on granulocytopoiesis in the slender salamanderThis investigation was supported by U. S. Public Health Service grant 1 RO1 AM11784-01 through the National Institute of Arthritis and Metabolic Diseases. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 427-441 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The morphology of differentiating heterophils and eosinophils of the slender salamander, Batrachoseps attenuatus, was studied with electron microscopy. Enzymes of the granules of both cell types appear to arise from the Golgi cisternae. An agranular stem cell was not observed and the least differentiated cell type encountered was an “early” promyelocyte having small granules which are morphologically distinct from mature granules of either the heterophil or eosinophil series. Heterophil myelocytes and later stages contain only one population of granule which is fibrous in content. Eosinophils likewise possess but one type of granule; the granules are larger than those of heterophils, have a homogeneous content, and lack the crystallin core so characteristic of mammalian eosinophils.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630306
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 179
    Electronic Resource
    Electronic Resource
    Fine structure of canine Kupffer cells and their microtubule-containing cytosomesThis investigation was supported by United States Public Health Service research grants HE09311, 2T1 GM382-06, and HE06943. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 483-496 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrastructure of Kupffer cells of canine liver has been studied and described. Kupffer cell nuclei were elongated and irregular in shape having a prominent double nuclear envelope containing scattered ribosomes on the outer membrane. Mitochondria were small, relatively scarce, and contained few mitochondrial granules. Elements of endoplasmic reticulum were scarce and highly irregular in form. In general, the cytoplasm was less dense than hepatocytes and contained fewer organelles which were less compactly arranged than in hepatocytes. Microbodies were not observed in any of the Kupffer cells studied. The cytoplasm contained various numbers of large phagosomes but consistently contained numerous dense cytosomes of various sizes. The most striking finding was that many cytosomes and phagosomes contained large numbers of short microtubules approximately 350 Å in diameter which were arranged in clusters and were associated with membanes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630401
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 180
    Electronic Resource
    Electronic Resource
    Inclusion bodies of type II alveolar cells: Species differences and morphogenesisSupported by Research grant HD-02459 from National Institute of Health, U. S. Public Health Service and U-1880 from Health Research Council of the City of New York. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 525-541 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In order to evaluate pathological alterations of the inclusion bodies of Type II cells in the mammalian lung, normal morphology of inclusions has been studied in rabbit, sheep, rat, mouse, dog, hamster and guinea pig. In rabbit, and sheep the fetal development of the inclusions has also been investigated.After a standard method of fixation, three different types of inclusions have been found in the species studied. The first type of inclusion is seen in the fetal rabbit, fetal sheep, dog, rat and mouse. In these species the inclusions contain heavily osmiophilic, coarsely lamellar material. In all of these species, the inclusions seem to form from an interaction between tubulo-vesicular bodies, located near the Golgi apparatus, and multivesicular bodies. These are certain variations in the appearance of the inclusions among these species.The second type of inclusion is seen in the hamster and guinea pig, in which lightly osmiophilic material accumulates during the maturation of the inclusions. In these species, a granular dense body seems to occupy an important role in the formation of the inclusion bodies.In the third group, the postnatal rabbit and sheep, the inclusions appear vacuolated.It is postulated that the seemingly inconsistent results of the acid phosphatase activity of inclusions in several species may indeed be a reflection of species differences in the mode of formation of inclusion bodies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630405
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 181
    Electronic Resource
    Electronic Resource
    Fine structure of neuromuscular relationships in mouse heartThis investigation was supported by Research grants HE-07605 and NB-07299 from the National Institutes of Health, U.S.P.H.S., Bethesda, Md. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 575-585 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Hearts of mice were fixed in osmium tetroxide, embedded in Epon, sectioned for electron miscroscopy and stained with uranyl acetate. Various regions of these hearts were examined for neuromuscular relationships. Unmyelinated nerve bundles with partial Schwann cell investment, frequently are present within the perivascular spaces of capillaries and arterioles in the myocardium of all regions studied. Neuromuscular junctions are located in the myocardium of the right atrium, the inter-ventricular septum and the outer ventricular walls. Neuromuscular junctions seem to be absent from the myocardium of the apex. Previously reported neuro-effector relationships within various tissues are discussed in relation to the findings of this study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630409
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 182
    Electronic Resource
    Electronic Resource
    Structure and evolutionary implications of the musculi arrectores pilorum in chiroptera (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 587-593 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Skin samples from 16 genera and 19 species of bats were studied histologically. These and review of the literature revealed musculi arrectores pilorum composed of smooth muscle present only in Megachiroptera and complex cutaneous striated muscle systems best developed in Microchiroptera. Smooth muscle arrectores of the mid-dorsal neck skin of Hypsignathus monstrosus are described in detail and resemble those of generalized structure in other mammalian Orders. Shoulder pouches of the epaulet bats (Epomophorus and Epomops) contain compound smooth and striated muscle systems for eversion of hair tufts and pouch respectively. An evolutionary trend within the Chiroptera of reduction in smooth muscle arrectores and replacement by integumentary striated muscle fibers is suggested.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630410
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 183
    Electronic Resource
    Electronic Resource
    The testicular interstitial cells of a lion and a three-toed slothThis research was supported by USPHS grant AM CA 11376-07. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 35-45 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of testicular interstitial cells of lion and three-toed sloth showed an abundance of agranular endoplasmic reticulum, mitochondria and lipid droplets. Mitochondria were usually small and rod to rounded in shape, but large bizarre forms, such as triangular, oval and rounded with tubular and lamellar cristae were also observed. Mitochondria with lamellar cristae occurred in lion, but not in three-toed sloth. These cristae were highly developed and appeared unique for the testicular interstitial cells. Both small and large mitochondria closely adhered to lipid droplets which were found singly or in clusters. The stored lipid droplets probably serve as a major source of substrate in androgen biosynthesis. The possible role of agranular endoplasmic reticulum in androgen biosynthesis is suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640103
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 184
    Electronic Resource
    Electronic Resource
    The globule leucocyte in the intestinal mucosa of the cat: A histochemical, light and electron microscopic study (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 79-99 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Globule leucocytes (GL) first noted by Weill ('19) in the intestinal tract of certain mammals, have been described, since, in many species. The classification and function of these cells, however, is still under discussion. We have studied GL in the cat using histochemistry at light and electron microscopic levels. In this species, GL are concentrated in the intestinal mucosa; they are found less frequently in the gallbladder and only rarely in other organs. GL are usually located between the epithelial cells of the gut, seldom in the underlying lamina propria. They appear to be migratory cells of mesenchymal origin, representing an independent cell population. GL are characterized by large eosinophilic globules in their cytoplasm. The globules contain strongly basic proteins associated with phospholipids and neutral mucosubstances which, in the colon, are encased in a capsule of sulfated mucosubstances. At the ultrastructural level the typical globules consist of a dense, homogeneous matrix enclosed by a single membrane; they show, however, great variation in their morphologic appearance, reflecting, possibly, different stages in the process of accretion and utilization of their content.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640106
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 185
    Electronic Resource
    Electronic Resource
    The influence of pituitary hormones and norepinephrine on the size of adipose cells in organ cultureThis project was supported in part by N.I.H. grant HD-00142. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 141-151 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The technique of organ culture was used to test the effects of various pituitary hormones and norepinephrine on the size of brown and white adipose cells of mice. The hormonal effects were measured by means of histologic analysis and cell width measurements. A concentration of 10 μg/ml of somatotropin (STH), adrenocorticotropin (ACTH) or lipotropin (LPH) was sufficient to reduce the size and content of intracellular lipid in white fat cells while a concentration of 100 μg/ml was required for similar effects on brown fat cells. Norepinephrine, at concentrations of 0.1 μg/ml or 1.0 μg/ml, was sufficient to reduce markedly the size and lipid content of both types of adipose cells. On a molar basis, these hormones acted in a similar range of concentration. The reduction in size and amount of intracellular lipid in brown and white adipose cells by STH, ACTH, and LPH were prevented when combined with 10 μg/ml of insulin. Insulin prevented the lipid depletion effect of norepinephrine in brown but not white adipose cells.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640202
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 186
    Electronic Resource
    Electronic Resource
    Masthead (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650401
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 187
    Electronic Resource
    Electronic Resource
    Books Received (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 451-452 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650312
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 188
    Electronic Resource
    Electronic Resource
    The primitive erythropoietic series in the chick embryo, studied with the electron microscope (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 453-465 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrastructural aspects of the chick embryo primitive erythrocytic cell series are described. There are two points of particular interest: the appearance of ferritin in erythroblast cytoplasm in 20 somite stage embryos and the behaviour of ribosomes during the red cell maturation period, both with regard to their progressive diminution and how they are grouped in polyribosomes. Ribosomes are still present in primitive series erythrocytes, although fewer than in the immature cells, and they are mainly in group form.A morphological comparison of the primitive red series erythrocytes with those of the definitive red series has also been made.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650402
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 189
    Electronic Resource
    Electronic Resource
    Studies on the innervation of the medial meniscus in the human knee jointA preliminary report on these studies was presented at the Annual Meeting of the Anatomical Society of Australia and New Zealand in May 1968. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 485-491 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Histological and ultrastructural studies on the medial meniscus in the human knee joint show that nerve fibres, both myelinated and unmyelinated, extend from the periarticular plexus into the meniscus as far as the intermediate third. These neural elements are not exclusively paravascular in position and it is reasonable to postulate a function other than vasomotor or vasosensory for them.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650404
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 190
    Electronic Resource
    Electronic Resource
    The fine structure of the vasa recta and associated nerves in the rabbit kidney (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 503-513 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of the vasa recta and associated nerves has been studied in the rabbit. Vasa recta were first identified in groups of two or three and were accompanied by small groups of axons. A number of these axons contained granulated, agranular and dense-cored vesicles. As the vasa recta subdivided, the muscle coat consisted of a single layer of smooth muscle cells. Additional large axon bundles were observed accompanying this segment of the vasa recta. Some of these axons also contained granulated, agranular and dense-cored vesicles in varying proportions. Further towards the medulla, smooth muscle cells were replaced by others which had irregular collections of filaments within their cytoplasm. These in turn were replaced by cells having a characteristic band of filaments on their luminal aspects. Nerves were only identified adjacent to those parts of the vasa recta which included smooth muscle cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650406
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 191
    Electronic Resource
    Electronic Resource
    Ultrastructural organization and histochemical profile of adult fowl choroid plexus epitheliumThe histochemical study was supported in part by grant NB04722 of the National Institutes of Health. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 515-529 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The choroid plexus epithelial cell of adult fowl is columnar with an irregular apical border of smooth-surfaced microvilli and cilia. Bi-nucleate cells occur frequently. Coated plasmalemma pits and vesicles (∼ 1000 Å) are present at all margins of the cell. Smaller coated vesicles (600-700 Å), found in variable numbers throughout the apical zone, tend to be concentrated in the Golgi region. Sparse to profuse amounts of granular endoplasmic reticulum (RER) are found throughout the cell with tubular whorled configurations occasionally noted in the subnuclear cytoplasm. Parallel arrays of RER extend from the cell base, around the nucleus, to the Golgi zone. Oval, fine granular masses occur in the subnuclear area. Free ribosomes are distributed throughout the cell. An array of diverse dense bodies and a few multi-vesicular bodies lie near the Golgi complex. Variable amounts of smooth ER are present in the supra-nuclear region. Toluidine blue, pH 4.0, demonstrates a heavy subnuclear condensation of cytoplasmic RNA. After sulfation, the apical margin and basement membrane are made metachromatic by Toluidine blue. A diastase-resistant, strong PAS positive reaction occurs in the apical border and basement membrane. Lateral cell margins are lightly stained with PAS. Alcian blue and colloidal iron intensely color the microvillous border. Bromphenol blue and bromsulfalein heavily stain the apical and basal zones of all cells.
    Additional Material: 23 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650407
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 192
    Electronic Resource
    Electronic Resource
    The structure of the interalveolar septum of the mammalian lungSupported by United States Public Health Service grant 5RO1-A108410-02 and by a grant from the Stonywold Foundation of New York. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 467-483 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Light and electron microscopic examination of serial transverse sections of interalveolar septa of hamster lung have demonstrated a virtually continuous connective tissue sheet of variable thickness in the interalveolar septum. This central sheet, like connective tissue elsewhere, is composed of ground substance in which are immersed cells, collagen and elastin. A capillary network lies on each surface of this sheet. The capillary basement membrane is continuous with the central sheet but in contrast to it is thin, uniform and devoid of cells, collagen or elastin. Capillaries on one surface frequently anastomose directly through the septum with capillaries on the opposite surface.The central sheet is shown to be virtually continuous despite frequent thinning. Whenever cells, collagen or elastin occur in the interalveolar septum, it is always in the central sheet. The efficiency of this arrangement in combining optimum gas conductance with adequate mechanical support is pointed out.The central sheet is also continuous with the perivascular connective tissue cuff and thus may serve as an important route of extracellular fluid transport to the perivascular lymphatics.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650403
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 193
    Electronic Resource
    Electronic Resource
    Histology of the oviduct of the leopard frog, Rana pipiensThis work was supported in part by a grant from The University of Michigan Cancer Research Institute and a training grant from the National Institutes of Health (USPHS Grant No. GM989).Adapted in part from a dissertation submitted at The University of Michigan in partial fulfillment of the requirements for the degree of Doctor of Philosophy. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 493-501 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The first one to three mm of each of the paired female oviducts in Rana pipiensconsists of a folded mucosa lacking tubular glands and enclosed by a serosa. Most of the remainder of the oviduct is lined by a folded mucosa richly endowed with simple tubular, jelly-secreting glands. The final one to two cm of the uterine portion of the oviduct, however, has a smooth mucosal lining which lacks tubular glands. Jelly-secreting glands penetrate to the base of the mucosa and open to the lumen between ridges capped with ciliated or mucous secreting epithelial cells. As cells of the jelly-secreting glands grow and differentiate during the summer, they accumulate a granular secretory product which exhibits basohpilia in hematoxylinstained specimens. This is the essential change in the histological structure of the gland throughout the growing season.The adult male oviduct is a solid cord of cells for about one-third of its length. The inferior two-thirds, however, is like the female oviduct at an intermediate stage of seasonal growth with gland cells containing secretory granules which exhibit basophilia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650405
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 194
    Electronic Resource
    Electronic Resource
    Fate of 3H-ribose in the rat as detected by radioautography (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 543-557 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Light and electron microscopic radioautographs of the tissues of young rats which were sacrificed at various times after a single 3H-ribose injection revealed a wide distribution of the label.Nuclear reactions were seen over hepatocytes and other cell types. After removal of RNA by treatment with RNAse, most nuclear reactions were absent; they were, therefore, attributed to the incorporation of label into newly-synthesized RNA. In about 2% of the nuclei, however, labeling persisted after RNAse, but was absent after DNAse treatment, indicating uptake into newly-synthesized DNA. Hence, ribose may be taken up into nucleic acidsundergoing synthesis.In cells of liver and cartilage as well as in some muscle fibers, moderate reaction appeared over glycogen areas. Removal of the label by salivary amylase confirmed its uptake into glycogen.In mucous and other secretory cells, amylase resistant radioautographic reactions appeared over the Golgi region and later over secretion products. Presumably the label was incorporated into the glycoproteinmoieties of these secretions.Many, if not all, cells in the body appear to be able to utilize free exogenous ribose. It is presumed that ribose is first phosphorylated and then either incorporated into the RNA and DNA being synthesized in the nucleus or converted into the glucose or fructose derivatives used for glycogen and glycoprotein synthesis in the cytoplasm. That these pathways may play a significant physiological role is suggested by the recent finding of free ribose in the blood.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650409
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 195
    Electronic Resource
    Electronic Resource
    Studies on hypoxia V. Effects of anoxia on developing connective tissue cells in ratsSupported in part by Grants HD-03147, DE-02311 and DE-02731 from the National Institutes of Health, U.S. Public Health Service. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 531-541 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The effect of anoxia on protein synthesis of developing connective tissue cells was studied by radioautography. Neonatal rats were subjected to anoxia for 20 minutes and were immediately injected with 3 μc/gm body weight of leucine-H3intraperitoneally. They were sacrificed at different intervals after injection. Control animals were handled identically, except that atmospheric air was made available. The heads of the animals were prepared for radioautography in the standard manner. The number of grains was counted over individual fibrobalsts, osteoblasts and chondrocytes of histologically comparable regions, and the data were statistically evaluated.The number of grains per cell was significantly lower in experimental animals sacrificed at one hour after the anoxic treatment and leucine-H3administration. At this time, the average grain number per cell in the experimental animal was less than 50% of the control. The difference was about 20% by four hours and was negligible after 24 hours. The result is interpreted to indicate that the overall protein synthesis in connective tissues is immediately but temporarily suppressed by anoxia and that such suppression might lead to a later functional disturbance among these cells.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650408
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 196
    Electronic Resource
    Electronic Resource
    Actinomycin D and amphibian cells in vitro: Effects on monolayers, postmitotic nucleolar reconstruction and nucleolar emptying at different temperaturesSupported by National Cancer Institute Postdoctoral Fellowship no. 1-F2-CA-35, 462-01 APA awarded to Dr. Burns and administered by Dr. Duryee and a NIH General Research Support grant 5SO1 FR 5350.Send reprint requests to Dr. Burns, Department of Anatomy, University of Arkansas Medical Center, Little Rock, Arkansas, 72201. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 559-567 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This study was designed to investigate (1) the effects of actinomycin D on monolayers of cells grown from explants of lung from frogs (R. pipiens) and newts (T. viridescens), (2) the effect of actinomycin D on postmitotic nucleolar reconstruction and (3) the possible protective effect that low temperature may have on the cytotoxic action of actinomycin D. Time-lapse cinematographic studies as well as sequential phase photomicrographic analyses resulted in several conclusions. 10.0 μg/cm3actinomycin D caused a slow emptying of nucleoli followed by cytoplasmic shrinkage and eventual cell death. This cytotoxic effect proceeded from the periphery of the monolayer toward the explant. 100.0 μg/cm3actinomycin D consistently emptied nucleoli in three hours at 25-27°C. Precooled monolayers treated with 100.0 μg/cm3cold actinomycin D for three hours at 4°C showed no nucleolar emptying. Normal cells reconstructed definitive nucleoli 60 minutes after the first early anaphase movements of the chromosomes were noticed. 1.0 μg/cm3actinomycin D delayed, but did not prevent postmitotic nucleolar reconstruction. 10.0 μg/cm3actinomycin D did, however, prevent postmitotic nucleolar reconstruction during the time period studied (190 minutes after early anaphase movement of the chromosomes).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650410
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 197
    Electronic Resource
    Electronic Resource
    The fine structure of the secretory cells of the uterus (shell gland) of the chickenThis investigation was supported by United States Public Health Service Fellowship 1-F2-GM-28,066-01 from the National Institute of General Medical Sciences and by United States Public Health Service Training grant 2 TIGM 94 07. (1969)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 128 (1969), S. 35-65 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The secretory processes in the shell gland of laying chickens were the subject of this study. Three cell types contribute secretory material to the forming egg: ciliated and non-ciliated columnar cells of the uterine surface epithelium, and cells of tubular glands in the mucosa. The ciliated cells as well as the non-ciliated cells have microvilli, which undergo changes in form and extent during the secretory cycle. At the final stages of shell formation they resemble stereocilia. It is postulated that the microvilli of both cells are active in the production of the cuticle of the shell.The ciliated cell which has both cilia and microvilli manufactures secretory granules which arise from the Golgi complex in varying amounts throughout the egg laying cycle. Granule production reaches its greatest intensity during the early stages of shell deposition. The ciliated cell probably supplies proteinaceous material to the matrix of the forming egg shell.The non-ciliated cell has only microvilli. Secretory granules, containing an acid mucopolysaccharide, arise from the Golgi complex. Some granules are extruded into the uterine lumen where they supply the egg shell with organic matrix. Others migrate towards the supranuclear zone. Here a number of them disintegrate. This is accompanied by the formation of a large membraneless space, which is termed “vacuoloid.” Subsequently the vacuoloid regresses and during regression an extensive rough endoplasmic reticulum with numerous polyribosomes of spiral configuration appears. It is suggested that material in the vacuoloid originating from the disintegrating granules is resynthesized and utilized for the formation of secretory product.The uterine tubular gland cells have irregular, frondlike microvilli. During egg shell deposition, these microvilli form large blebs and are probably related to the elaboration of a watery, calcium-containing fluid.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051280103
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 198
    Electronic Resource
    Electronic Resource
    Electron microscopy of cardiac tissue in a primitive vertebrate Myxine glutinosaThis work was supported by a grant-in-aid from the American Heart Association, and USPHS grant HE-0664 (HEP). (1969)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 128 (1969), S. 131-157 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Hearts of the Atlantic hagfish, Myxine glutinosa were studied with the electron microscope after prefixation in phosphate buffered glutaraldehyde or buffered formalin and subsequent postifxation in phosphate buffered osmium tetroxide. Epicardial, myocardial and endocardial layers are identified; however the hearts of Myxine lack an extensive capillary system comparable to the coronary vessels of other vertebrate heart tissues. Instead, blood is supplied to cells via an elaborate system of channels which extend between numerous trabeculae that make up the cardiac wall of this organism. Fine structural features of special interest include the presence of numerous dense granules (chromaffin granules) within myofibers and also specific granular cells which lack the contractile elements that are characteristic of both skeletal and cardiac myofibers. Another prominent feature noted includes an elaborate system of tubular invaginations within the subjacent sarcoplasm. These elements appear to be specific for the myofibers. They are continuous with the plasma membrane and project into the peripheral sarcoplasmic matrix. Crystalline inclusions are also observed in the sarcoplasm of the myofibers. These are compared with similar inclusions in other cellular components. The Golgi complex is very extensive in the myofibers of Myxine, and granules of varying sizes and densities often appear in the vicinity of the Golgi saccules. The observations suggest that the numerous vesicles around the Golgi Complex represent intermediate stages in the formation of the chromaffin granules. The structure and function of the extensive tubular invaginations are compared with the transverse tubules reported in several mammalian heart tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051280202
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 199
    Electronic Resource
    Electronic Resource
    Regeneration and supernumerary limb formation under sparsely innervated conditionsSupported by grants-in-aid from the National Science Foundation (GB-2618; GB-7748) and the National Institutes of Health NB-04128-(07).We are indebted to Mrs. Mary Thornton for expert assistance in the surgical operations and histology. (1969)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 127 (1969), S. 225-232 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Normally, urodele limb regeneration is nerve-dependent. Reduction in nerve-dependency has been reported for regenerating, transplanted newt limbs (Singer and Mutterperl, '63). Aneurogenic limbs can regenerate without nerves (Yntema, '59). Induction of supernumerary limbs may be obtained from aneurogenic limbs of larval Ambystoma after transplantation orthotopically to innervated larvae and with normal nerve ingrowth to the limb transplant prevented by repeated section of brachial nerves. Of the 13 (of 43) grafts with supernumeraries, nerve counts showed 11 with 0-5; 1 with 5-10; and 1 with 20+ fibers. Orthotopically grafted aneurogenic limbs allowed to become innervated showed 14 supernumeraries in 49 grafts. This supernumerary limb induction is thus not nerve-dependent.Normally, innervated larval Ambystoma limbs grafted orthotopically and heteroplastically regenerated in 17 of 37 cases after repeated section of brachial nerves. Of the 17 regenerates nerve counts showed 4 with 0-5; 5 with 5-10; 7 with 10-19; and 1 with 20+ fibers. Larval limbs heteroplastically transplanted may require very few or no nerves for regeneration.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051270207
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 200
    Electronic Resource
    Electronic Resource
    Masthead (1969)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 127 (1969) 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051270301
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...