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  • 1
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    Diskrete Mathematik und ihre Anwendungen: Auf dem Weg zu authentischem Mathematikunterricht (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Das heutige Leben ist durchdrungen von komplexen Technologien. Ohne Kommunikationsnetze, Internet, Mobilfunk, Logistik, Verkehrstechnik, medizinische Apparate, etc. könnte die moderne Gesellschaft nicht funktionieren. Fast alle dieser Technologien haben einen hohen Mathematikanteil. Der "normale Bürger"' weiss davon nichts, der Schulunterricht könnte dem ein wenig abhelfen. Einige mathematische Aspekte dieser Technologien sind einfach und sogar spielerisch intuitiv zugänglich. Solche Anwendungen, die zusätzlich noch der Lebensumwelt der Schüler zugehören, können dazu genutzt werden, die mathematische Modellierung, also die mathematische Herangehensweise an die Lösung praktischer Fragen, anschaulich zu erläutern. Gerade in der diskreten Mathematik können hier, quasi "nebenbei" mathematische Theorien erarbeitet und Teilaspekte (Definitionen, Fragestellungen, einfache Sachverhalte) durch eigenständiges Entdecken der Schüler entwickelt werden. Wir beginnen mit einigen Beispielen.
    Schlagwort(e): ddc:510
    Sprache: Deutsch
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  • 2
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    Wegeprobleme der Graphentheorie (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Den kürzesten Weg in einem Graphen zu finden ist ein klassisches Problem der Graphentheorie. Über einen Vortrag zu diesem Thema beim Tag der Mathematik 2007 von R. Borndörfer kam ich in Kontakt mit dem Konrad-Zuse-Zentrum (ZIB), das sich u.a. mit Wegeoptimierung beschäftigt. Ein Forschungsschwerpunkt dort ist im Rahmen eines Projekts zur Chipverifikation das Zählen von Lösungen, das, wie wir sehen werden, eng mit dem Zählen von Wegen zusammenhängt. Anhand von zwei Fragen aus der Graphentheorie soll diese Facharbeit unterschiedliche Lösungsmethoden untersuchen. Wie bestimmt man den kürzesten Weg zwischen zwei Knoten in einem Graphen und wie findet man alle möglichen Wege? Nach einer Einführung in die Graphentheorie und einer Konkretisierung der Probleme wird zunächst für beide eine Lösung mit auf Graphen basierenden Algorithmen vorgestellt. Während der Algorithmus von Dijkstra sehr bekannt ist, habe ich für das Zählen von Wegen einen eigenen Algorithmus auf der Basis der Tiefensuche entwickelt. Im zweiten Teil der Arbeit wird das Konzept der ganzzahligen Programmierung vorgestellt und die Lösungsmöglichkeiten für Wegeprobleme, die sich darüber ergeben. Schließlich wurden die vorgestellten Algorithmen am Beispiel des S- und U-Bahnnetzes von Berlin implementiert und mit Programmen, die die gleichen Fragen über ganzzahlige Programmierung lösen, verglichen.
    Schlagwort(e): ddc:510
    Sprache: Deutsch
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  • 3
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    A Perturbation Result for Dynamical Contact Problems (2008)
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    Publikationsdatum: 2016-06-09
    Beschreibung: This paper is intended to be a first step towards the continuous dependence of dynamical contact problems on the initial data as well as the uniqueness of a solution. Moreover, it provides the basis for a proof of the convergence of popular time integration schemes as the Newmark method. We study a frictionless dynamical contact problem between both linearly elastic and viscoelastic bodies which is formulated via the Signorini contact conditions. For viscoelastic materials fulfilling the Kelvin-Voigt constitutive law, we find a characterization of the class of problems which satisfy a perturbation result in a non-trivial mix of norms in function space. This characterization is given in the form of a stability condition on the contact stresses at the contact boundaries. Furthermore, we present perturbation results for two well-established approximations of the classical Signorini condition: The Signorini condition formulated in velocities and the model of normal compliance, both satisfying even a sharper version of our stability condition.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 4
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    An Integer Programming Algorithm for Routing Optimization in IP Networks (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Most data networks nowadays use shortest path protocols to route the traffic. Given administrative routing lengths for the links of the network, all data packets are sent along shortest paths with respect to these lengths from their source to their destination. In this paper, we present an integer programming algorithm for the minimum congestion unsplittable shortest path routing problem, which arises in the operational planning of such networks. Given a capacitated directed graph and a set of communication demands, the goal is to find routing lengths that define a unique shortest path for each demand and minimize the maximum congestion over all links in the resulting routing. We illustrate the general decomposition approach our algorithm is based on, present the integer and linear programming models used to solve the master and the client problem, and discuss the most important implementational aspects. Finally, we report computational results for various benchmark problems, which demonstrate the efficiency of our algorithm.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 5
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    The Line Connectivity Problem (2008)
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    Publikationsdatum: 2020-12-15
    Beschreibung: This paper introduces the "line connectivity problem", a generalization of the Steiner tree problem and a special case of the line planning problem. We study its complexity and give an IP formulation in terms of an exponential number of constraints associated with "line cut constraints". These inequalities can be separated in polynomial time. We also generalize the Steiner partition inequalities.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 6
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    Using Model Counting to Find Optimal Distinguishing Tests (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Testing is the process of stimulating a system with inputs in order to reveal hidden parts of the system state. In the case of non-deterministic systems, the difficulty arises that an input pattern can generate several possible outcomes. Some of these outcomes allow to distinguish between different hypotheses about the system state, while others do~not. In this paper, we present a novel approach to find, for non-deterministic systems modeled as constraints over variables, tests that allow to distinguish among the hypotheses as good as possible. The idea is to assess the quality of a test by determining the ratio of distinguishing (good) and not distinguishing (bad) outcomes. This measure refines previous notions proposed in the literature on model-based testing and can be computed using model counting techniques. We propose and analyze a greedy-type algorithm to solve this test optimization problem, using existing model counters as a building block. We give preliminary experimental results of our method, and discuss possible improvements.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 7
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    On the Effects of Minor Changes in Model Formulations (2008)
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    Publikationsdatum: 2021-08-05
    Beschreibung: Starting with the description of the Traveling Salesmen Problem formulation as given by van Vyve and Wolsey in the article Approximate extended formulations'', we investigate the effects of small variations onto the performance of contemporary mixed integer programming solvers. We will show that even minor changes in the formulation of the model can result in performance difference of more than a factor of 1000. As the results show it is not obvious which changes will result in performance improvements and which not.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 8
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    Detecting Orbitopal Symmetries (2008)
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    Publikationsdatum: 2022-03-14
    Beschreibung: Orbitopes can be used to handle symmetries which arise in integer programming formulations with an inherent assignment structure. We investigate the detection of symmetries appearing in this approach. We show that detecting so-called orbitopal symmetries is graph-isomorphism hard in general, but can be performed in linear time if the assignment structure is known.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 9
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    Optimization and Identification in Regional Hyperthermia (2008)
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    Publikationsdatum: 2019-01-29
    Beschreibung: Regional hyperthermia is a cancer therapy aiming at heating tumors using phased array applicators. This article provides an overview over current mathematical challenges of delivering individually optimal treatments. The focus is on therapy planning and identification of technical as well as physiological quantities from MR thermometry measurements.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 10
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    On Efficiency and Accuracy in Cardioelectric Simulation (2008)
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    Publikationsdatum: 2019-05-10
    Beschreibung: Reasons for the failure of adaptive methods to deliver improved efficiency when integrating monodomain models for myocardiac excitation are discussed. Two closely related techniques for reducing the computational complexity of linearly implicit integrators, deliberate sparsing and splitting, are investigated with respect to their impact on computing time and accuracy.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 11
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    Models for Periodic Timetabling (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: We investigate the computation of periodic timetables for public transport by mixed integer programming. After introducing the problem, we describe two mathematical models for periodic timetabling, the PERIODIC EVENT SCHEDULING PROBLEM (PESP) and the QUADRATIC SEMI-ASSIGNMENT PROBLEM. Specifically, we give an overview of existing integer programming (IP) formulations for both models. An important contribution of our work are new IP formulations for the PESP based on time discretization. We provide an analytical comparison of these formulations and describe different techniques that allow a more efficient solution by mixed integer programming. In a preliminary computational study, on the basis of standard IP solvers, we compare different formulations for computing periodic timetables. Our results justify a further investigation of the time discretization approach. Typically the timetable is optimized for the current traffic situation. The main difficulty with this approach is that after introducing the new timetable the passengers’ travel behavior may differ from that assumed for the computation. Motivated by this problem, we examine an iterative timetabling procedure that is a combination of timetable computation and passenger routing. We discuss the algorithmic issues of the passenger routing and study properties of the computed timetables. Finally, we confirm our theoretical results on the basis of an own implementation.
    Beschreibung: Wir untersuchen die Berechnung von Taktfahrplänen für den öffentlichen Verkehr mit gemischt-ganzzahliger Programmierung (MIP). Im Anschluss an die Problembeschreibung, stellen wir zwei mathematische Modellierungen vor, das PERIODIC EVENT SCHEDULING PROBLEM (PESP) und das QUADRATIC SEMI-ASSIGNMENT PROBLEM. Wichtiger Bestandteil ist ein Überblick über existierende ganzzahlige Formulierungen beider Modelle. Wir entwickeln neue ganzzahlige Formulierungen für das PESP auf der Basis von Zeitdiskretisierung. Diese werden analytisch miteinander verglichen und wir beschreiben verschiedene Techniken, die eine effizientere Lösung der Formulierungen mit gemischt-ganzzahliger Programmierung ermöglichen. In einer ersten Rechenstudie, unter Verwendung gängiger MIP-Löser, vergleichen wir verschiedene ganzzahlige Formulierungen zur Berechnung von Taktfahrplänen. Unsere Ergebnisse rechtfertigen eine weitere Untersuchung des Zeitdiskretisierungsansatzes. In der Regel werden Fahrpläne mit Bezug auf die gegenwärtige Verkehrssituation optimiert. Dies birgt jedoch folgendes Problem. Wenn der neue Fahrplan eingeführt wird, ist es möglich, dass die Passagiere ein anderes Fahrverhalten zu Tage legen, als für die Berechnung des Fahrplans angenommen wurde. Vor diesem Hintergrund behandeln wir ein iteratives Verfahren zur Berechnung von Taktfahrplänen. Dieses ist eine Kombination aus Fahrplanberechnung und Passagierrouting. Neben den algorithmischen Details des Passagierroutings untersuchen wir Eigenschaften der berechneten Fahrpläne. Abschließend bestätigen wir unsere theoretischen Ergebnisse auf Grundlage einer eigenen Implementierung des Verfahrens.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: masterthesis , doc-type:masterThesis
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  • 12
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    Experiments with nonlinear extensions to SCIP (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: This paper describes several experiments to explore the options for solving a class of mixed integer nonlinear programming problems that stem from a real-world mine production planning project. The only type of nonlinear constraints in these problems are bilinear equalities involving continuous variables, which enforce the ratios between elements in mixed material streams. A branch-and-bound algorithm to handle the integer variables has been tried in another project. However, this branch-and-bound algorithm is not effective for handling the nonlinear constraints. Therefore state-of-the-art nonlinear solvers are utilized to solve the resulting nonlinear subproblems in this work. The experiments were carried out using the NEOS server for optimization. After finding that current nonlinear programming solvers seem to lack suitable preprocessing capabilities, we preprocess the instances beforehand and use an heuristic approach to solve the nonlinear subproblems. In the appendix, we explain how to add a polynomial constraint handler that uses IPOPT as embedded nonlinear programming solver for the constraint programming framework SCIP. This is one of the crucial steps for implementing our algorithm in SCIP. We briefly described our approach and give an idea of the work involved.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 13
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    Tiefensuche: Bemerkungen zur Algorithmengeschichte (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Dieser kurze Aufsatz zur Algorithmengeschichte ist Eberhard Knobloch, meinem Lieblings-Mathematikhistoriker, zum 65. Geburtstag gewidmet. Eberhard Knobloch hat immer, wenn ich ihm eine historische Frage zur Mathematik stellte, eine Antwort gewusst – fast immer auch sofort. Erst als ich mich selbst ein wenig und dazu amateurhaft mit Mathematikgeschichte beschäftigte, wurde mir bewusst, wie schwierig dieses „Geschäft“ ist. Man muss nicht nur mehrere (alte) Sprachen beherrschen, sondern auch die wissenschaftliche Bedeutung von Begriffen und Symbolen in früheren Zeiten kennen. Man muss zusätzlich herausfinden, was zur Zeit der Entstehung der Texte „allgemeines Wissen“ war, insbesondere, was seinerzeit gültige Beweisideen und -schritte waren, und daher damals keiner präzisen Definition oder Einführung bedurfte. Es gibt aber noch eine Steigerung des historischen Schwierigkeitsgrades: Algorithmengeschichte. Dies möchte ich in diesem Artikel kurz darlegen in der Hoffnung, dass sich Wissenschaftshistoriker dieses Themas noch intensiver annehmen, als sie das bisher tun. Der Grund ist, dass heute Algorithmen viele Bereiche unserer Alltagswelt steuern und unser tägliches Leben oft von funktionierenden Algorithmen abhängt. Daher wäre eine bessere Kenntnis der Algorithmengeschichte von großem Interesse.
    Schlagwort(e): ddc:510
    Sprache: Deutsch
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  • 14
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    State constrained optimal control problems with states of low regularity (2008)
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    Publikationsdatum: 2016-06-09
    Beschreibung: We consider first order optimality conditions for state constrained optimal control problems. In particular we study the case where the state equation has not enough regularity to admit existence of a Slater point in function space. We overcome this difficulty by a special transformation. Under a density condition we show existence of Lagrange multipliers, which have a representation via measures and additional regularity properties.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 15
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    Properties of Reduced Reversible Markov Chains (2008)
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    Publikationsdatum: 2016-06-09
    Beschreibung: The enormous time lag between fast atomic motion and complex pro- tein folding events makes it almost impossible to compute molecular dy- namics on a high resolution. A common way to tackle this problem is to model the system dynamics as a Markov process. Yet for large molec- ular systems the resulting Markov chains can hardly be handled due to the curse of dimensionality. Coarse graining methods can be used to re- duce the dimension of a Markov chain, but it is still unclear how far the coarse grained Markov chain resembles the original system. In order to answer this question, two different coarse-graining methods were analysed and compared: a classical set-based reduction method and an alternative subspace-based approach, which is based on membership vectors instead of sets. On the basis of a small toy system, it could be shown, that in con- trast to the subset-based approach, the subspace-based reduction method preserves the Markov property as well as the essential dynamics of the original system.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 16
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    Line Planning on Paths and Tree Networks with Applications to the Quito Trolebus System (2008)
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    Publikationsdatum: 2021-02-19
    Beschreibung: Line planning is an important step in the strategic planning process of a public transportation system. In this paper, we discuss an optimization model for this problem in order to minimize operation costs while guaranteeing a certain level of quality of service, in terms of available transport capacity. We analyze the problem for path and tree network topologies as well as several categories of line operation that are important for the Quito Trolebus system. It turns out that, from a computational complexity worst case point of view, the problem is hard in all but the most simple variants. In practice, however, instances based on real data from the Trolebus System in Quito can be solved quite well, and significant optimization potentials can be demonstrated.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 17
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    On the optimality of Least Recently Used (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: It is well known that competitive analysis yields too pessimistic results when applied to the paging problem and it also cannot make a distinction between many paging strategies. Many deterministic paging algorithms achieve the same competitive ratio, ranging from inefficient strategies as flush-when-full to the good performing least-recently-used (LRU). In this paper, we study this fundamental online problem from the viewpoint of stochastic dominance. We show that when sequences are drawn from distributions modelling locality of reference, LRU is stochastically better than any other online paging algorithm.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 18
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    Angebotsplanung im öffentlichen Nahverkehr (2008)
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    Publikationsdatum: 2020-12-15
    Beschreibung: Die Angebotsplanung im öffentlichen Nahverkehr umfasst die Aufgaben der Netz-, Linien-,Fahr- und Preisplanung. Wir stellen zwei mathematische Optimierungsmodelle zur Linien- und Preisplanung vor. Wir zeigen anhand von Berechnungen für die Verkehrsbetriebe in Potsdam(ViP), dass sich damit komplexe Zusammenhänge quantitativ analysieren lassen. Auf diese Weise untersuchen wir die Auswirkungen von Freiheitsgraden auf die Konstruktion von Linien und die Wahl von Reisewegen der Passagiere, Abhängigkeiten zwischen Kosten und Reisezeiten sowie den Einfluss verschiedener Preissysteme auf Nachfrage und Kostendeckung.
    Schlagwort(e): ddc:510
    Sprache: Deutsch
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  • 19
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    Constraint Integer Programming: a New Approach to Integrate CP and MIP (2008)
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    Publikationsdatum: 2022-03-14
    Beschreibung: This article introduces constraint integer programming (CIP), which is a novel way to combine constraint programming (CP) and mixed integer programming (MIP) methodologies. CIP is a generalization of MIP that supports the notion of general constraints as in CP. This approach is supported by the CIP framework SCIP, which also integrates techniques from SAT solving. SCIP is available in source code and free for non-commercial use. We demonstrate the usefulness of CIP on two tasks. First, we apply the constraint integer programming approach to pure mixed integer programs. Computational experiments show that SCIP is almost competitive to current state-of-the-art commercial MIP solvers. Second, we employ the CIP framework to solve chip design verification problems, which involve some highly non-linear constraint types that are very hard to handle by pure MIP solvers. The CIP approach is very effective here: it can apply the full sophisticated MIP machinery to the linear part of the problem, while dealing with the non-linear constraints by employing constraint programming techniques.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 20
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    An Extended Mathematical Framework for Barrier Methods in Function Space (2008)
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    Publikationsdatum: 2016-06-09
    Beschreibung: An extended mathematical framework for barrier methods for state constrained optimal control compared to [Schiela, ZIB-Report 07-07] is considered. This allows to apply the results derived there to more general classes of optimal control problems, in particular to boundary control and finite dimensional control.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 21
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    Counting solutions of integer programs using unrestricted subtree detection (2008)
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    Publikationsdatum: 2021-08-05
    Beschreibung: In the recent years there has been tremendous progress in the development of algorithms to find optimal solutions for integer programs. In many applications it is, however, desirable (or even necessary) to generate all feasible solutions. Examples arise in the areas of hardware and software verification and discrete geometry. In this paper, we investigate how to extend branch-and-cut integer programming frameworks to support the generation of all solutions. We propose a method to detect so-called unrestricted subtrees, which allows us to prune the integer program search tree and to collect several solutions simultaneously. We present computational results of this branch-and-count paradigm which show the potential of the unrestricted subtree detection.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 22
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    On the cardinality constrained matroid polytope (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Edmonds showed that the so-called rank inequalities and the nonnegativity constraints provide a complete linear description of the matroid polytope. By essentially adding Grötschel's cardinality forcing inequalities, we obtain a complete linear description of the cardinality constrained matroid polytope which is the convex hull of the incidence vectors of those independent sets that have a feasible cardinality. Moreover, we show how the separation problem for the cardinality forcing inequalities can be reduced to that for the rank inequalities. We also give necessary and sufficient conditions for a cardinality forcing inequality to be facet defining.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 23
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    On solving large systems of polynomial equations appearing in Discrete Differential Geometry (2008)
    Details
    Publikationsdatum: 2020-08-05
    Beschreibung: The paper describes a method for solution of very large overdetermined algebraic polynomial systems on an example that appears from a classification of all integrable 3-dimensional scalar discrete quasilinear equations $Q_3=0$ on an elementary cubic cell of the lattice ${\mathbb Z}^3$. The overdetermined polynomial algebraic system that has to be solved is far too large to be formulated. A probing' technique which replaces independent variables by random integers or zero allows to formulate subsets of this system. An automatic alteration of equation formulating steps and equation solving steps leads to an iteration process that solves the computational problem.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 24
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    Invertible Mappings of Nonlinear PDEs to Linear PDEs Through Admitted Conservation Laws (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: An algorithmic method using conservation law multipliers is introduced that yields necessary and sufficient conditions to find invertible mappings of a given nonlinear PDE to some linear PDE and to construct such a mapping when it exists. Previous methods yielded such conditions from admitted point or contact symmetries of the nonlinear PDE. Through examples, these two linearization approaches are contrasted.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 25
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    Classification of 3-dimensional integrable scalar discrete equations (2008)
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    Publikationsdatum: 2021-02-26
    Beschreibung: We classify all integrable 3-dimensional scalar discrete affine linear equations $Q_3=0$ on an elementary cubic cell of the lattice ${\mathbb Z}^3$. An equation $Q_3=0$ %of such form is called integrable if it may be consistently imposed on all $3$-dimensional elementary faces of the lattice ${\mathbb Z}^4$. Under the natural requirement of invariance of the equation under the action of the complete group of symmetries of the cube we prove that the only ontrivial(non-linearizable) integrable equation from this class is the well-known dBKP-system.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 26
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    About a Computer Algebra based online Mathtest (2008)
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    Publikationsdatum: 2020-12-11
    Beschreibung: The article describes the online mathematics test {\tt http://lie.math.brocku.ca/mathtest}, its typical applications and experiences gathered.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 27
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    TTPLIB 2008 - A Library for Train Timetabling Problems (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: We introduce (TTPlib), a data library for train timetabling problems that can be accessed at http://ttplib.zib.de. In version 1.0, the library contains data related to 50 scenarios. Most instances result from the combination of macroscopic railway networks and several train request sets for the German long distance area containing Hannover, Kassel and Fulda, short denoted by Ha-Ka-Fu. In this paper, we introduce the data concepts of TTPlib, describe the scenarios included in the library and provide a free visualization tool TraVis.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 28
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    The Parametric Solution of Underdetermined linear ODEs (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: The purpose of this paper is twofold. An immediate practical use of the presented algorithm is its applicability to the parametric solution of underdetermined linear ordinary differential equations (ODEs) with coefficients that are arbitrary analytic functions in the independent variable. A second conceptual aim is to present an algorithm that is in some sense dual to the fundamental Euclids algorithm, and thus an alternative to the special case of a Gr\"{o}bner basis algorithm as it is used for solving linear ODE-systems. In the paper Euclids algorithm and the new dual version' are compared and their complementary strengths are analysed on the task of solving underdetermined ODEs. An implementation of the described algorithm is interactively accessible at http://lie.math.brocku.ca/crack/uode.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 29
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    Probabilistic analysis of Online Bin Coloring algorithms via Stochastic Comparison (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: This paper proposes a new method for probabilistic analysis of online algorithms that is based on the notion of stochastic dominance. We develop the method for the Online Bin Coloring problem introduced by Krumke et al. Using methods for the stochastic comparison of Markov chains we establish the strong result that the performance of the online algorithm GreedyFit is stochastically dominated by the performance of the algorithm OneBin for any number of items processed. This result gives a more realistic picture than competitive analysis and explains the behavior observed in simulations.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 30
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    Models for Fare Planning in Public Transport (2008)
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    Publikationsdatum: 2020-12-15
    Beschreibung: The optimization of fare systems in public transit allows to pursue objectives such as the maximization of demand, revenue, profit, or social welfare. We propose a non-linear optimization approach to fare planning that is based on a detailed discrete choice model of user behavior. The approach allows to analyze different fare structures, optimization objectives, and operational scenarios involving, e.g., subsidies. We use the resulting models to compute optimized fare systems for the city of Potsdam, Germany.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 31
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    Solving Pseudo-Boolean Problems with SCIP (2008)
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    Publikationsdatum: 2022-03-14
    Beschreibung: Pseudo-Boolean problems generalize SAT problems by allowing linear constraints and a linear objective function. Different solvers, mainly having their roots in the SAT domain, have been proposed and compared,for instance, in Pseudo-Boolean evaluations. One can also formulate Pseudo-Boolean models as integer programming models. That is,Pseudo-Boolean problems lie on the border between the SAT domain and the integer programming field. In this paper, we approach Pseudo-Boolean problems from the integer programming side. We introduce the framework SCIP that implements constraint integer programming techniques. It integrates methods from constraint programming, integer programming, and SAT-solving: the solution of linear programming relaxations, propagation of linear as well as nonlinear constraints, and conflict analysis. We argue that this approach is suitable for Pseudo-Boolean instances containing general linear constraints, while it is less efficient for pure SAT problems. We present extensive computational experiments on the test set used for the Pseudo-Boolean evaluation 2007. We show that our approach is very efficient for optimization instances and competitive for feasibility problems. For the nonlinear parts, we also investigate the influence of linear programming relaxations and propagation methods on the performance. It turns out that both techniques are helpful for obtaining an efficient solution method.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: reportzib , doc-type:preprint
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  • 32
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    Planung von öffentlichem Personenverkehr (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Millionen von Menschen werden allein in Deutschland täglich von Bussen, Bahnen und Flugzeugen transportiert. Der öffentliche Personenverkehr (ÖV) ist von großer Bedeutung für die Lebensqualität einzelner aber auch für die Leistungsfähigkeit ganzer Regionen. Qualität und Effizienz von ÖV-Systemen hängen ab von politischen Rahmenbedingungen (staatlich geplant, wettbewerblich organisiert) und der Eignung der Infrastruktur (Schienensysteme, Flughafenstandorte), vom vorhandenen Verkehrsangebot (Fahr- und Flugplan), von der Verwendung angemessener Technologien (Informations-, Kontroll- und Buchungssysteme) und dem bestmöglichen Einsatz der Betriebsmittel (Energie, Fahrzeuge und Personal). Die hierbei auftretenden Entscheidungs-, Planungs- und Optimierungsprobleme sind z.T. gigantisch und "schreien" aufgrund ihrer hohen Komplexität nach Unterstützung durch Mathematik. Dieser Artikel skizziert den Stand und die Bedeutung des Einsatzes von Mathematik bei der Planung und Durchführung von öffentlichem Personenverkehr, beschreibt die bestehenden Herausforderungen und regt zukunftsweisende Maßnahmen an.
    Schlagwort(e): ddc:510
    Sprache: Deutsch
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  • 33
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    Development and test of a numerical model for pulse thermography in civil engineering (2008)
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    Publikationsdatum: 2019-05-10
    Beschreibung: Pulse thermography of concrete structures is used in civil engineering for detecting voids, honeycombing and delamination. The physical situation is readily modeled by Fourier's law. Despite the simplicity of the PDE structure, quantitatively realistic numerical 3D simulation faces two major obstacles. First, the short heating pulse induces a thin boundary layer at the heated surface which encapsulates all information and therefore has to be resolved faithfully. Even with adaptive mesh refinement techniques, obtaining useful accuracies requires an unsatisfactorily fine discretization. Second, bulk material parameters and boundary conditions are barely known exactly. We address both issues by a semi-analytic reformulation of the heat transport problem and by parameter identification. Numerical results are compared with measurements of test specimens.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 34
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    Barrier Methods for Optimal Control Problems with Convex Nonlinear Gradient Constraints (2008)
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    Publikationsdatum: 2016-06-09
    Beschreibung: In this paper we are concerned with the application of interior point methods in function space to gradient constrained optimal control problems, governed by partial differential equations. We will derive existence of solutions together with first order optimality conditions. Afterwards we show continuity of the central path, together with convergence rates depending on the interior point parameter.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 35
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    Interior Point Methods in Function Space for State Constraints - Inexact Newton and Adaptivity (2008)
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    Publikationsdatum: 2016-06-09
    Beschreibung: We consider an interior point method in function space for PDE constrained optimal control problems with state constraints. Our emphasis is on the construction and analysis of an algorithm that integrates a Newton path-following method with adaptive grid refinement. This is done in the framework of inexact Newton methods in function space, where the discretization error of each Newton step is controlled by adaptive grid refinement in the innermost loop. This allows to perform most of the required Newton steps on coarse grids, such that the overall computational time is dominated by the last few steps. For this purpose we propose an a-posteriori error estimator for a problem suited norm.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 36
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    Fair Ticket Prices in Public Transport (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Ticket pricing in public transport usually takes a welfare or mnemonics maximization point of view. These approaches do not consider fairness in the sense that users of a shared infrastructure should pay for the costs that they generate. We propose an ansatz to determine fair ticket prices that combines concepts from cooperative game theory and integer programming. An application to pricing railway tickets for the intercity network of the Netherlands demonstrates that, in this sense, prices that are much fairer than standard ones can be computed in this way.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 37
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    A sharp interface finite volume method for elliptic equations on Cartesian grids (2008)
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    Publikationsdatum: 2014-02-26
    Beschreibung: We present a second order sharp interface finite volume method for the solution of the three-dimensional poisson equation with variable coefficients on Cartesian grids. In particular, we focus on interface problems with discontinuities in the coefficient, the source term, the solution, and the fluxes across the interface. The method uses standard piecewiese trilinear finite elements for normal cells and a double piecewise trilinear ansatz for the solution on cells intersected by the interface resulting always in a compact 27-point stencil. Singularities associated with vanishing partial volumes of intersected grid cells are removed by a two-term asymptotic approach. In contrast to the 2D method presented by two of the authors in [M.~Oevermann, R.~Klein: A Cartesian grid finite volume method for elliptic equations with variable coefficients and embedded interfaces, J.~Comp.~Phys.~219 (2006)] we use a minimization technique to determine the unknown coefficients of the double trilinear ansatz. This simplifies the treatment of the different cut-cell types and avoids additional special operations for degenerated interface topologies. The resulting set of linear equations has been solved with a BiCGSTAB solver preconditioned with an algebraic multigrid. In various testcases -- including large coefficient ratios and non-smooth interfaces -- the method achieves second order of accuracy in the L_inf and L_2 norm.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 38
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    Cardinality Constrained Combinatorial Optimization: Complexity and Polyhedra (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: Given a combinatorial optimization problem and a subset $N$ of natural numbers, we obtain a cardinality constrained version of this problem by permitting only those feasible solutions whose cardinalities are elements of $N$. In this paper we briefly touch on questions that addresses common grounds and differences of the complexity of a combinatorial optimization problem and its cardinality constrained version. Afterwards we focus on polytopes associated with cardinality constrained combinatorial optimization problems. Given an integer programming formulation for a combinatorial optimization problem, by essentially adding Grötschel's cardinality forcing inequalities, we obtain an integer programming formulation for its cardinality restricted version. Since the cardinality forcing inequalities in their original form are mostly not facet defining for the associated polyhedra, we discuss possibilities to strengthen them.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 39
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    On the complexity of column generation in survivable network design with path-based survivability mechanisms (2008)
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    Publikationsdatum: 2020-08-05
    Beschreibung: This survey concerns optimization problems arising in the design of survivable communication networks. It turns out that such problems can be modeled in a natural way as non-compact linear programming formulations based on multicommodity flow network models. These non-compact formulations involve an exponential number of path flow variables, and therefore require column generation to be solved to optimality. We consider several path-based survivability mechanisms and present results, both known and new, on the complexity of the corresponding column generation problems (called the pricing problems). We discuss results for the case of the single link (or node) failures scenarios, and extend the considerations to multiple link failures. Further, we classify the design problems corresponding to different survivability mechanisms according to the structure of their pricing problem. Finally, we show that almost all encountered pricing problems are hard to solve for scenarios admitting multiple failures.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 40
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    On the Line Planning Problem in Tree Networks (2008)
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    Publikationsdatum: 2021-02-19
    Beschreibung: We introduce an optimization model for the line planning problem in a public transportation system that aims at minimizing operational costs while ensuring a given level of quality of service in terms of available transport capacity. We discuss the computational complexity of the model for tree network topologies and line structures that arise in a real-world application at the Trolebus Integrated System in Quito. Computational results for this system are reported.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 41
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    Line Planning on Paths and Tree Networks with Applications to the Quito Trolebus System (Extended Abstract) (2008)
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    Publikationsdatum: 2021-02-19
    Beschreibung: Line planning is an important step in the strategic planning process of a public transportation system. In this paper, we discuss an optimization model for this problem in order to minimize operation costs while guaranteeing a certain level of quality of service, in terms of available transport capacity. We analyze the problem for path and tree network topologies as well as several categories of line operation that are important for the Quito Trolebus system. It turns out that, from a computational complexity worst case point of view, the problem is hard in all but the most simple variants. In practice, however, instances based on real data from the Trolebus System in Quito can be solved quite well, and significant optimization potentials can be demonstrated.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 42
    Digitale Medien
    Digitale Medien
    Impacts of Bioremediation Schemes on Bacterial Population in Naphthalene-Contaminated Marine Sediments (2006)
    Springer
    Biodegradation 17 (2006), S. 227-235 
    Details
    ISSN: 1572-9729
    Schlagwort(e): community fingerprint ; polycyclic aromatic hydrocarbon ; 16S rRNA
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Energietechnik , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract Microcosm experiments were conduced in which the surface of marine sediment was contaminated with naphthalene and subjected to either of three different bioremediation schemes, i.e., biostimulation (BS) by supplementing with slow-release nitrogen and phosphorus fertilizers, bioaugmentation (BA) by inoculating with Cycloclasticus sp. E2, an aromatics-degrading bacterium identified to play an important role for aromatic-hydrocarbon degradation in marine environments and combination (CB) of BS and BA. These three schemes were found to be similarly effective for removing naphthalene, while naphthalene disappearance in sediment without any treatment (WT) was slower than those in the treated sediments. Shifts in bacterial populations during and after bioremediation were analyzed by denaturing gradient gel electrophoresis (DGGE) of PCR-amplified 16S rRNA gene fragments. It was found that the Cycloclasticus rRNA type occurred as the strongest bands in the course of naphthalene degradation. Clustering analysis of DGGE profiles showed that bacterial populations in the WT, BS and CB sediments differed consistently from those in the uncontaminated control, while the profile for the BA sediment was finally included in the cluster for uncontaminated control sediments after a 150-day treatment. The results suggest that bioaugmentation with ecologically competent pollutant-degrading bacteria is an ecologically promising bioremediation scheme.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s10532-005-5018-9
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  • 43
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    Meshless Methods in Confirmation Dynamics (2006)
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    Publikationsdatum: 2016-06-09
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 44
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    Kombinatorische Optimierung –Inhalte und Methoden für einen authentischen Mathematikunterricht (2006)
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    Publikationsdatum: 2020-08-05
    Beschreibung: wird nachgereicht
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 45
    Digitale Medien
    Digitale Medien
    Cladistic analysis of 5S rRNA and 16S rRNA secondary and primary structure—The evolution of eukaryotes and their relation to archaebacteria (1986)
    Springer
    Journal of molecular evolution 24 (1986), S. 152-166 
    Details
    ISSN: 1432-1432
    Schlagwort(e): 5S rRNA ; 16S rRNA ; Archaebacteria ; Cladistics
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The secondary structure of 5S rRNA has been elucidated by a cladistic analysis resulting in minimal models for eukaryotes, eubacteria, and halophilic-methanogenic archaebacteria, as well as for an ur-5S rRNA. This ancestor of all present-day 5S rRNA molecules is compared with an ur-tRNA and can be fitted into a tRNA-like structure allowing tertiary-structure interactions at the equivalent positions. A phylogenetic analysis of eukaryotic 5SrRNA and 16S rRNA sequences confirms particular monophyletic taxa: rhodophytes (red algae), chlorobionts (green algae and plants), metazoans (multicellular animals), euglenozoans (euglenids and trypanosomatids), a group of zygomycetes (excluding Kickxellales), a group of ascomycetes (excluding Protomycetales), two distinct groups of basidiomycetes, and a group consisting of phaeophyceans (brown algae) and oomycetes (water molds). The Euglenozoa show a distinct relation to the Eumycota (true fungi) and Metazoa. An analysis of archaebacterial sequences substantiates the paraphyletic nature of this third urkingdom defining the eubacteria as a sister group of the halophile-methanogens and defining the eukaryotes as a sister group of a particular lineage of the eocytes/sulfur-dependents. The latter fact implies that even the eocytes/sulfur-dependent archaebacteria are paraphyletic.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02099963
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  • 46
    Digitale Medien
    Digitale Medien
    Fluorescence high performance liquid chromatographic determination of 3α-hydroxysteroids in urine of 21-hydroxylase deficiency (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 1-6 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A fluorescence high performance liquid chromatographic method using an immobilized 3α-hydroxysteroid dehydrogenase column as a post-column enzymatic reactor was developed for the determination of corticosteroid metabolites in the urine of subjects with congenital adrenal hyperplasia. 3α-Hydroxysteroids, such as pregnanetriol, pregnanediol and pregnanetriolone, in the eluate from μ-Bondapak phenyl column (300 × 3.9 mm I.D.) using 0.05% ammonium phosphate buffer (pH 7.1)-acetonitrile-methanol (100: 55: 15) as the mobile phase was mixed with NAD+ solution in the enzyme column at 30 °C to generate NADH, which was monitored by a fluorophotometric detector. Each steroid was measured at the 2.5 μg/dl at the highest sensitivity of the detector. The mean recoveries and reproducibilities were 91.5-108.2% with 0.9-6.5% (CV%).
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010102
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  • 47
    Digitale Medien
    Digitale Medien
    Measurement of urinary cystine and cysteinyl-penicillamine in patients with cystinuria (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 21-26 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A high-performance liquid chromatographic method with electrochemical detection (LC/EC) was developed to measure cystine and cysteinyl-penicillamine disulfide in the urine of patients screened or treated for cystinuria. Urine was acidified, centrifuged to remove urinary protein, diluted and injected. The disulfides were separated on a reversed-phase column, reduced at the upstream electrode of a dual electrochemical detector with gold-mercury amalgam (Au/Hg) electrodes and the resultant thiols measured at the downstream electrode. The sample preparation is simple, the analysis rapid, specimens can be easily batched and the specificity of the method is better than those of two other separative procedures with which it was compared. The coefficient of variation for cystine in cystinuric urine is 6.7%, 5.5% and 3.2% for levels of 0.09, 0.52 and 1.02 mmol/l respectively, and for cysteinyl-penicillamine disulfide 2.6% and 7.5% for levels of 0.45 and 0.98 mmol/l respectively. Urine for analysis of these disulfides should not be collected within 24 hours of administration of the radiopaque agent diatrizoate but no other interference to the assay has been noted. This method is suitable as a screen for cystinuria in patients with renal tract calculi, for ongoing monitoring of cystinuric patients and to check patient compliance with d-penicillamine therapy.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010106
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  • 48
    Digitale Medien
    Digitale Medien
    Early identification of isovaleric aciduria using photodiode array detection for liquid chromatographic profiling of urinary carboxylic acids (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 38-40 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The 190 nm high performance liquid chromatographic photodiode array profiling of the urinary carboxylic acids of the first urine of a newborn affected with isovaleric aciduria afforded an abnormal peak at 27.8 min. This peak was greatly increased in the carboxylic acid profiling of the 14 h urine sample from the same infant. Isolation of this peak by fraction collecting; solvent extraction of the eluent; trimethylsilyl derivatization of the residue and gas chromatographic/mass spectrometric analysis identified the compound as isovalerylglycine. Correlation of the 190 nm absorbance of isovalerylglycine (y) with concentration (x) afforded a least squares curve: y = 476.4x - 13.72 (r = 0.99) run-to-run variation 6.92%; day-to-day variation 8.88%; with a minimum detectable concentration of 25 μg/ml.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010109
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  • 49
    Digitale Medien
    Digitale Medien
    Combined use of lectin affinity chromatography and endo-β-galactosidase to study polylactosamine sequences isolated from haemopoietic cell surfaces (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 41-47 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The trypsin-sensitive glycopeptides from cell surfaces of a multipotential murine haemopoietic cell line (DE) have been studied using serial lectin affinity chromatography on columns of immobilized lentil lectin (LCA), concanavalin A (Con A), and wheat-germ agglutinin (WGA). WGA-binding material consisted of glycopeptides that failed to bind to LCA and Con A. Step elution from the WGA-column with 0.01-, 0.1-, 0.5- and 1.0 M N-acetyl-D-glucosamine yielded four affinity classes of glycopeptide (WGA-W, WGA-I, WGA-S and WGA-SS respectively). WGA-W, WGA-I and WGA-S contained both alkali-stable (N-linked) and alkali-labile (O-linked) carbohydrate on high molecular weight glycopeptides. The WGA-SS fraction contained only N-linked carbohydrate. N-linked glycopeptides isolated from each WGA-binding class differed in molecular size, relative N-acetylneuraminic acid content and affinity for Ricinus communis 120 agglutinin. endo-β-Galactosidase digestion showed that these glycopeptides contained polylactosamine-type glycans. Gel filtration profiles of the enzyme treated materials were different for each WGA-binding population suggesting variation in branching patterns and/or substitution with fucose residues. Affinity chromatography has shown that the WGA binding molecules are the major glycopeptide group at DE cell surfaces.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010110
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  • 50
    Digitale Medien
    Digitale Medien
    Separation and studies of serum proteins with aid of aqueous two-phase systems containing dyes as affinity ligands (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 64-77 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 21 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010205
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  • 51
    Digitale Medien
    Digitale Medien
    Analysis of urine and faecal porphyrins by HPLC coupled to an advanced automated sample processor (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 93-94 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010208
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  • 52
    Digitale Medien
    Digitale Medien
    Paper chromatography of urinary amino acids. A 30 year survey of dietary influences on the normal pattern, and patients' results (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 95-100 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: In the clinical laboratory, paper chromatography is still the most useful, simple, inexpensive procedure for initial identification of abnormalities of amino acid excretion. The results of its use for more than 8000 paediatric and adult renal patients is surveyed. Nonspecific generalized aminoaciduria was the most frequent abnormality found, comprising some 70% of abnormal results, with cystine-lysinuria the next most common. The identification of the abnormal excretory pattern of amino acids as distinct from the normal was complicated by the effects of the New Zealand diet. In particular, valine, citrulline, hydroxyproline and glutamic acid are found in considerable amounts as part of the normal pattern. Their dietary origin is discussed. Varying mixtures of monosaccharides and disaccharides occurred in association with a range of amino acid patterns.
    Zusätzliches Material: 4 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010302
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  • 53
    Digitale Medien
    Digitale Medien
    Use of biological fluids for the rapid diagnosis of potentially lethal inherited disorders of human purine and pyrimidine metabolism (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 109-118 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: Inherited purine and pyrimidine disorders may be associated with serious, sometimes life-threatening consequences. Early and accurate diagnosis is essential. Difficulties encountered when using existing high pressure liquid chromatographic (HPLC) methods led to the development of an improved method based on prior fractionation of urine. The advantages are as follows. 1. Production of fingerprints demonstrating altered urinary excretion patterns characteristic of any one of ten different disorders, in 30 minutes. 2. Positive identification and quantification by comparison with established methods (using conventional chromatography, electrophoresis and UV spectrophotometry) in addition to specific retention times and characteristic UV absorbance ratios at two separate wavelengths (245 and 280 nm) by HPLC. 3. Direct analysis of all the purines and pyrimidines normally found in human body fluids as well as identification of abnormal compounds. 4. Short time between successive analyses while maintaining excellent resolution between compounds of interest and column longevity. 5. Improved separation of the different adenine-based compounds encountered in some disorders, plus demonstration of potential interference by dietary or drug metabolites. 6. Applicability to the monitoring of therapy involving a variety of different purine and pyrimidine analogues.Particular attention should be paid to sample preparation. Plasma profiles will confirm the diagnosis in some, but not all, of these disorders.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010305
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  • 54
    Digitale Medien
    Digitale Medien
    Measurement of penbutolol and 4-hydroxypenbutolol in plasma or serum by HPLC (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 140-142 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A simple HPLC method for penbutolol and 4-hydroxypenbutolol assay has been developed. Plasma or serum (200 μl) is vortex-mixed (30 s) with Tris solution (2 M, pH 10.6) containing an internal standard (50 μl) and methyl t-butyl ether (200 μl). After centrifugation, the extract (100 μl) is analysed using an unmodified silica column (250 × 5 mm ID) and iso-octane-methanol-methyl t-butyl ether (55:25:20) containing ammonium perchlorate (10 mM, pH 5.7) as eluent and with fluorescence detection. No interference has been encountered and the limit of accurate measurement for both compounds is 5 μg/l.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010309
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  • 55
    Digitale Medien
    Digitale Medien
    Metabolic profiling of opioid peptides in canine pituitary and selected brain regions using HPLC with a radioreceptor assay detector (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 126-139 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A combination of gradient reversed-phase high performance liquid chromatography (RP/HPLC) with a radioreceptor assay detector that uses two ligands is used to obtain effectively the metabolic profile of endogenous receptoractive opioid peptides in the canine pituitary and in seven selected brain regions including the hypothalamus, caudate nucleus, mid-brain, amygdala, thalamus, pons-medulla, and the hippocampus. Gradient RP/HPLC separates a mixture of endogenous peptides over a wide range of hydrophobicities. A novel opioid preparation from canine limbic system synaptosomes is utilized in a radioreceptorassay screen; tritiated etorphine (ET) or D-2ala, D-5leu-leucine enkephalin (DADL) is used as the competitively displaced ligand. This receptor-rich preparation contains several receptor types, and thus serves well as a screen with the required low level of specificity. Subsequent analysis with other detectors of high specificity (MS, RIA) will follow this screen in other studies. Etorphine interacts with several of the opioid peptide-preferring receptors, whereas DADL is more specific towards the delta receptor that preferentially binds the smaller pentapeptides of the enkephalin family. The highest amount of peptide receptor activity found in this study is in the pituitary tissue, a smaller amount in the hypothalamus and caudate nucleus, and still lower amounts in the other five brain tissue extracts. This variation in peptide concentration most probably reflects three separate factors that operate in this biologic system: differential tissue-specific processing patterns of the large peptide precursors; distribution of the three opioid peptide systems; and the receptor preparation and the radioligand used in the assay. The structures of the receptoractive compounds in each RP/HPLC peak await mass spectrometric confirmation.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010308
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  • 56
    Digitale Medien
    Digitale Medien
    Subcellular distribution of rat pituitary homogenates by poly(ethylene glycol)-dextran countercurrent partitioning (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 12-14 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: Rat pituitary homogenates were subjected to two phase countercurrent partition in a poly(ethylene glycol)-dextran mixture using a simple apparatus with enhanced gravity to facilitate the phase separations. Assay of the fractions for organelle marker enzymes and prolactin after 17 transfers showed similar distributions for endoplasmic reticulum, lysosomes, prolactin granules and plasma membrane at the lowest dextran concentrations. Increasing the dextran concentrations had a differential effect on the various organelles. Excellent resolution of endoplasmic reticulum from the other organelles was obtained and marked organelle heterogeneity was demonstrated. Two-phase countercurrent partition thus offers an alternative approach to the subcellular fractionation of pituitary homogenates and should prove useful in separating endoplasmic reticulum from plasma membrane and other cell components.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010104
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  • 57
    Digitale Medien
    Digitale Medien
    Amino acid composition analysis of minute amounts of cysteine-containing proteins using 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and 4-fluoro-7-nitro-2,1,3-benzoxadiazole in combination with HPLC (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 15-20 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The simultaneous determination of amino acid composition including cysteine of egg albumin, a model protein containing a/s cysteine residue, is reported. All the thiol groups of the cysteine residue(s) of egg albumin were labelled with 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole, a fluorogenic reagent for thiol groups. The labeled egg albumin was hydrolyzed in 6N HCl at 110°C for 24 h. The hydrolysate was lyophilized, derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole, a fluorogenic reagent for amines, and subjected to HPLC. 18 derivatized amino acids including double labelled cysteine were separated within 90 min on a Nucleosil ODS column (150 mm × 4.6 mm i.d.; 5 μm), and detected at 530 nm (ex. 470 nm) in a range from 90 fmol (aspartic acid) to 1.3 pmol (cysteine) (S/N = 3). Composition ratios of amino acids of egg albumin were similar to theoretical values except for methionine, which would be destroyed under the present acid hydrolysis condition. Analytical methods for cysteine residues are reviewed, and the availability of fluorogenic reagents having the benzofurazan structure is also discussed.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010105
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  • 58
    Digitale Medien
    Digitale Medien
    Thin layer chromatography overlay technique in the analysis of the binding of the solubilized protoxin of Bacillus thuringiensis var. kurstaki to an insect glycosphingolipid of known structure (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 31-37 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The hypothesis tested was that a particular glycoconjugate(s) in the exposed cell-surface membrane of susceptible insect cells acts as a receptor and/or modulator for the specific interaction with the protoxin/activated toxin of the δ-endotoxin of Bacillus thuringiensis var. kurstaki. As candidates, the total neutral and acidic fraction glycolipids, and the isolated neutral glycosphingolipid components, were screened for binding activity by the thin layer chromatogram overlay technique. The main protoxin/activated toxin-binding glycolipid in the neutral fraction (5B) had the structure: Gal(α1-3)GalNAc(β1-4)GlcNAc(β1-3)Man(β1-4)Glc(β1-1)Cer. The main protoxin/activated toxin-binding glycolipid in the acidic fraction was designated band 1, the structure of which is at present unknown. The possibility that the component 5B carbohydrate sequence may also function as a toxin-binding site of relevant insect plasma membrane glycoproteins is discussed.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010108
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  • 59
    Digitale Medien
    Digitale Medien
    Masthead (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986) 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010201
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  • 60
    Digitale Medien
    Digitale Medien
    Determination of clozapine and its metabolites in serum and urine by reversed phase HPLC (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 53-57 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A rapid, specific and sensitive method using reversed phase HPLC for the simultaneous determination of clozapine and its two metabolites in serum and urine has been developed. The mobile phase was a mixture of 67% (v/v) methanol in water containing 0.4% tetramethylethylenediamine and 0.32% acetic acid (pH 5.5). The influence of methanol content, the pH of the mobile phase and the effect of adding alkylammonium ions as peak tailing reducer in the mobile phase have been investigated. The solvent for extracting clozapine from serum and urine was ether. 50 μ1 of 0.25 M H2SO4 solution was used to redissolve the dry residue to eliminate the endogenous compounds which could otherwise be eluted together with clozapine from the HPLC column. The analysis of a single sample was accomplished within half an hour. The identities of the chromatographic peaks of clozapine and its N-demethyl metabolite collected from the patient urine sample were confirmed by mass spectrometry. The method is sufficiently sensitive (5 ng/ml) and reproducible (CV 2.9%-6.7%) for clinical and pharmacokinetic studies, and preliminary results in these respects are presented.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010203
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  • 61
    Digitale Medien
    Digitale Medien
    Masthead (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986) 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010301
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  • 62
    Digitale Medien
    Digitale Medien
    Metabolic studies of explosives. 5. Detection and analysis of 2,4,6-trinitrotoluene and its metabolites in urine of munition workers by micro liquid chromatography/mass spectrometry (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 123-125 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: Metabolites of 2,4,6-trinitrotoluene (TNT) were found in the urine of a group of TNT munition workers. The urine extracts were analysed by micro liquid chromatography/mass spectrometry. The metabolites found included 2-amino-4,6-dinitrotoluene, 4-amino-2,6-dinitrotoluene, 2,4-diamino-6-nitrotoluene, 2,6-diamino-4-nitrotoluene and untransformed TNT. The detection limit of the metabolites in urine was 0.1 ng/ml for 20 ml urine samples.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010307
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  • 63
    Digitale Medien
    Digitale Medien
    Masthead (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986) 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010401
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  • 64
    Digitale Medien
    Digitale Medien
    Simple determination of forphenicinol in human plasma and erythrocytes by HPLC with native fluorescence detection (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 143-146 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A high performance liquid chromatographic method is described for monitoring forphenicinol, a possible therapeutic drug for cancer and muscular dystrophy, in human plasma and erythrocytes. Forphenicinol in the deproteinized samples was separated from interfering biogenic substances on an aminopropyl-bonded silica (Unicil NH2) column within 10 minutes with isocratic elution, and determined with fluorescence detection. The detection limits for forphenicinol in plasma and erythrocytes are 65 pmol (12.8 ng)/ml and 160 pmol (31.5 ng)/ml, respectively, corresponding to 2 pmol each in a 100 μl injection volume. The method is very simple, and sensitive enough to permit the quantification of forphenicinol in the blood samples from man dosed with forphenicinol.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010402
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  • 65
    Digitale Medien
    Digitale Medien
    Solid phase extraction and isocratic separation of urinary porphyrins by HPLC (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 159-162 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A method for determining urine porphyrins by HPLC is described. In the preliminary step, porphyrins are purified in high yields and concentrated by low pressure reverse-phase chromatography on C18 (octadecylsilane bonded silica) cartridge. Porphyrins are stable for 10 days after adsorption on C18 cartridge. The separation of porphyrin esters is performed on an aminopropyl-bonded silica column with an eluting system containing n-heptane and ethyl acetate. The system enables rapid isocratic separation of porphyrin methyl esters with high selectivity. The simplicity and reproducibility of the whole procedure allows its application to the routine analysis of urinary porphyrins in the clinical laboratory.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010406
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  • 66
    Digitale Medien
    Digitale Medien
    Opioid peptides in the cerebrospinal fluid of Alzheimer patients (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 155-158 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: Endogenous opioid receptoractive peptides in the cerebrospinal fluid (CSF) of human controls and in those patients diagnosed as having senile dementia of the Alzheimer's type (SDAT) are measured with a radioreceptorassay following HPLC separation. [3H]Etorphine is the ligand used to detect in the HPLC fractions the presence of those endogenous peptides that preferentially interact with several opioid receptors. The RRA uses a receptor-rich P2 fraction extracted from a canine limbic system. The total opioid peptide content found in the HPLC fractions 6-20 (to avoid salts in fractions 1-5) of SDAT CSF (383 ± 187 pmol ME-equivalents per ml CSF) is significantly higher than the corresponding total from patients with no known neurological disorders (89.1 ± 46.3 pmol ME-equivalents per ml).
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010405
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  • 67
    Digitale Medien
    Digitale Medien
    HPLC determination of orthophosphate coexisting with large amounts of organophosphates in biological samples (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 169-172 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A simple and accurate HPLC method for the determination of Orthophosphate in the presence of large amounts of organophosphates is described. The method is based on the formation and separation of the molybdenum Orthophosphate complex. In order to prevent the hydrolysis of organophosphates, the sample was deproteinized with silicotungstate in acetate buffer (pH 4.0) under ice-cooling and then treated with ammonium molybdate in maleate buffer (pH 7.0). The sample was injected onto Styragel 60 Å column (5 mm ID × 100 mm) with 38% (v/v) acetonitrile containing 0.3 M sulfuric acid as eluent. Detection was at 310 nm. The method was applied to the determination of Orthophosphate in liver, kidney, spleen and mouse blood.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010408
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  • 68
    Digitale Medien
    Digitale Medien
    HPLC of trazodone in serum after microscale protein precipitation (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 177-179 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: Trazodone, an anti-depressant medication, is found in serum in the 500-1000 ng/mL range in patients taking therapeutic doses. Because of this relatively high concentration, it has been possible to devise an HPLC assay system using the rapid, convenient microscale procedure described previously by Lam et al. (Clin. Chem. 26, 963 1980) to prepare the sample for chromatography. To 0.1 mL serum were added 0.1 mL acetonitrile and 10 μL of 10% zinc sulfate in water. The mixture was centrifuged and 50 μL of the clear supernatant was injected into a reversed-phase column which was eluted with 65% 0.05 M potassium phosphate-35% acetonitrile, with detection by ultraviolet absorbance at 210 nm. The trazodone elutes in 6 min, clearly resolved from endogenous interferences. The recovery of trazodone added to serum was better than 90%. Peak height was proportional to concentrations in the serum sample from 125 ng/mL to 3000 ng/mL.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010410
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  • 69
    Digitale Medien
    Digitale Medien
    Masthead (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986) 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010101
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  • 70
    Digitale Medien
    Digitale Medien
    Biosynthesis of bloodgroup I and i antigens. A sensitive and specific assay of UDP-GlcNAc:β-galactoside β1 → 3-N-acetylglucosaminyltransferase activity in hematopoietic cells by HPLC (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 104-108 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A sensitive HPLC method for the assay of UDP-GlcNAc:β-galactoside β1 → 3-N-acetylglucosaminyltransferase activity was developed. Using lactose as an acceptor, the formation of the product GlcNAcβ1 → 3Galβ1 → 4Glc can be determined without interference by substrates resulting from enzymatic and chemical breakdown of the donor substrate UDP-GlcNAc. The method is very specific since products of other transferase reactions, which potentially may be formed in the incubations in vitro, elute at positions different from that of GlcNAcβ1 → 3Galβ1 → 4Glc.By use of this assay method it could be demonstrated that normal and malignant hematopoietic cells and cell-lines, with the exception of erythrocytes and reticulocytes, contain β1 → 3-N-acetylglucosaminyltransferase activity.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010304
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  • 71
    Digitale Medien
    Digitale Medien
    The determination of nivacortol in plasma using HPLC (1986)
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 1 (1986), S. 151-154 
    Details
    ISSN: 0269-3879
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: A high performance liquid chromatographic method with ultraviolet detection was developed for the determination of nivacortol (WIN 27914) in biological samples. The drug was isolated from human plasma by using a solid-phase extraction and eluted with ethanol. The solvent was evaporated and the residue dissolved in the chromatographic eluent. The sample was subjected to chromatography on a C8 silica column and eluted with a gradient of acetonitrile in 0.1 M sodium acetate buffer, pH 6.5. A single concentration of a structural analogue (WIN 31338) was used as internal standard for the quantitative determination of the analyte. The plasma concentrations were below that needed to suppress ACTH secretion by pituitary cells in culture and did not suppress plasma ACTH in Nelson's syndrome.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bmc.1130010404
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  • 72
    Digitale Medien
    Digitale Medien
    Capillary GC analysis of diesel fuels using simultaneous parallel triple detection (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 39-43 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography, GC ; Fused silica capillary columns ; Parallel triple detection ; Diesel fuels ; Polyaromatic hydrocarbons ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Diesel fuels from different parts of the UK have been analyzed for polycyclic aromatic hydrocarbons (PAH), nitrogen-containing PAH, and sulfur-containing PAH using capillary column GC with simultaneous parallel triple detection. The concentrations of polyaromatic compounds (PAC) were high and showed considerable variability amongst the fuels. The PAH are mainly naphthalene, fluorene, and phenanthrene and their alkylated homologs; the PANH are mainly carbazole and its methyl derivatives; the PASH are mainly dibenzothiophene and its methyl derivatives.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090107
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  • 73
    Digitale Medien
    Digitale Medien
    One-step procedure for the preparation of glass capillary columns with immobilized Carbowax 20M (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 240-241 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography, GC ; Glass capillary columns ; Stationary phase immobilization ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090408
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  • 74
    Digitale Medien
    Digitale Medien
    A linear relationship between partition ratio and composition of a binary mobile phase in reversed-phase liquid chromatography using chemically bonded stationary phases (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 236-239 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, LC ; Reversed phase ; Chemically bonded phases ; Mixed eluents ; Partition effects ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: A simple linear relationship which enables the effect of the composition of a binary mobile phase on the retention of a solute to be assessed in reverse phase liquid chromatography using a bonded stationary phase has been derived. The equations have been tested using published experimental data.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090407
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  • 75
    Digitale Medien
    Digitale Medien
    Optical resolution of α-amino acid derivatives by carbon dioxide-supercritical fluid chromatography on the chiral stationary phase, N-formyl-valine bonded silica gel (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 249-250 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Supercritical fluid chromatography, SFC ; Chiral stationary phase, CSP ; Optical resolution ; α-Amino acid derivatives ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090410
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  • 76
    Digitale Medien
    Digitale Medien
    Masthead (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986) 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090401
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  • 77
    Digitale Medien
    Digitale Medien
    Supercritical fluid injection of high-molecular-weight polycyclic aromatic compounds in capillary supercritical fluid chromatography (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 213-217 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Capillary supercritical fluid chromatography ; Injection system ; Polycyclic aromatic compounds ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: A sample introduction system for capillary supercritical fluid chromatography, which allows the dissolution of the sample in the supercritical mobile phase before being introduced into the column, was constructed and evaluated. Supercritical n-pentane was shown to solvate high-molecular-weight polycyclic aromatic compounds that could not be solvated using typical liquid solvents. In addition, split injection of a supercritical fluid solution was found to be more reproducible than split injections of a liquid solution. The potential of such an injection system was demonstrated, although further developments are needed in order to make the technique of practically utility.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090404
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  • 78
    Digitale Medien
    Digitale Medien
    Quantitative HPTLC determination of selenium (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 224-235 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Thin-layer chromatography, HPTLC ; Biological matrices ; Fluorimetric detection ; Selenium ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: The present determination of selenium in biological matrices by HPTLC with in situ fluorimetric detection is an accurate alternative method, comparable to other established methods such as photometry, polarography, neutron activation, or X-ray fluorescence analysis, gas chromatography, and atomic absorption spectrometry.The excellent sensitivity of this procedure is proved by the detection limit of 250 fg of selenium per spot (using purified 2,3,1-naphthoselenodiazole). The oxidation of organic matrices, applying a novel digestion procedure, may be carried out with little instrumental expenditure.Sample preparation steps, such as the oxidation of selenium to Se (VI) and subsequent reduction to Se (IV) do not lead to significant random or systematic errors, nor does the digestion step, if an optimized procedure is used.A recovery rate of 103% and nearly parallel calibration curves for digested selenocysteine standards compared with spiked human serum samples demonstrate the accurate quantitative preparation of a biological matrix. Any interfering metal ions can be masked by addition of chelate-forming reagents.
    Zusätzliches Material: 24 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090406
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  • 79
    Digitale Medien
    Digitale Medien
    Fluorometric determination of haloperidol by high performance liquid chromatography (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 252-254 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, HPLC ; Post-column derivatization reaction ; Fluorogenic reaction ; Haloperidol ; N1-Methylnicotinamide chloride ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090412
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  • 80
    Digitale Medien
    Digitale Medien
    Chromatography calendar (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 260-260 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090415
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  • 81
    Digitale Medien
    Digitale Medien
    Masthead (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986) 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090501
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  • 82
    Digitale Medien
    Digitale Medien
    Chromatography calendar (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 289-290 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090508
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  • 83
    Digitale Medien
    Digitale Medien
    Simple press-fit connectors for flexible fused silica tubing in gas-liquid chromatography (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 295-297 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas-liquid chromatography, GC ; Fused silica tubing ; Connector ; Coupling ; Press-fit ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090510
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  • 84
    Digitale Medien
    Digitale Medien
    Synthesis of non-porous silica supports for HPLC from porous silica gels (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 304-305 
    Details
    ISSN: 0935-6304
    Schlagwort(e): HPLC ; Non-porous supports ; Tetra-ortho silicates ; Commercial supports ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090514
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  • 85
    Digitale Medien
    Digitale Medien
    Product news (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 314-316 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090519
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  • 86
    Digitale Medien
    Digitale Medien
    Sample capacity of open tubular and fused silica capillary micro-packed columns (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 312-313 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography ; Fused silica capillary micro-packed columns ; Open tubular columns ; Sample capacity ; Trace analysis ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090518
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  • 87
    Digitale Medien
    Digitale Medien
    Electron capture detector response to low electron affinity aromatic hydrocarbons using positive ion stabilization and alkyl chloride sensitization (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 320-327 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography ; Electron capture detector, ECD ; Electron capture sensitization ; Polynuclear aromatic hydrocarbons ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: The electron capture detector (ECD) response to numerous aromatic hydrocarbons of low electron affinity (EA) is shown to be detrimentally affected by two processes which compete with and typically overwhelm the electron capture reactions of these molecules. It is shown that the effects of these two undesired reactions can be eliminated by the permanent addition of trimethylamine and one of several alkyl monochlorides to the detector make-up gas. These modifications of the detector gas result in greatly increased sensitivity, increased linearity, and increased reproducibility of response. A kinetic model for the ECD responses of low EA resonance capture molecules is developed which appears to explain these improvements.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090602
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  • 88
    Digitale Medien
    Digitale Medien
    Kovats and lee retention indices determined by gas chromatography/mass spectrometry for organic compounds of environmental interest (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 328-334 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography ; GC/MS ; Fused silica (capillary) columns ; Retention index data ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Retention indices of standard organic compounds of environmental interest were determined by gas chromatography/mass spectrometry, using a DB-5 fused-silica capillary column. Retention indices are useful references for tentative compound identification by gas chromatography, or confirmation by gas chromatography/mass spectrometry. They provide elution order for isomers that might be indistinguishable based on mass spectra. Modified Kovats and Lee retention indices are given for polycyclic aromatic hydrocarbons; sulfur heterocycles; nitrogen heterocycles; aromatic amines; oxygen heterocycles; phenols; alcohols; ketones; alkanes; nitriles; and methylesters of fatty, dicarboxylic, and aromatic acids for comparison and reference. Retention index values for heterocycles by gas chromatography/mass spectrometry are comparable with gas chromatography values previously reported.
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090603
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  • 89
    Digitale Medien
    Digitale Medien
    Preparation of glass capillary columns coated with immobilized OV-240-OH (33% cyanopropyl substituted, OH-terminated). An approach to improve the inertness and thermal stability of cyanoalkyl polysiloxane coatings (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 350-355 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography ; Capillary columns, glass ; OV-240-H, 33% cyanopropyl ; Immobilization by condensation ; Crosslinker, dimethyltetramethoxysiloxane ; in situ methylation, diazomethane ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Coating intensely leached glass capillaries with OV-240-OH, the most polar commercially available OH-terminated polysiloxane phase at the present time, is described. Beside chemical bonding of the phase via condensation with silanol groups of the support, additional immobilization using dimethyltetramethoxysiloxane as a crosslinker is carried out. After in situ methylation of the immobilized coating, and transformation of acidic impurities of the cyanopropyl substituted phase into the respective methyl esters, increased inertness of the column was observed. Working instructions are given, and processes involved are discussed.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090607
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  • 90
    Digitale Medien
    Digitale Medien
    Chromatography calendar (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 366-372 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090614
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  • 91
    Digitale Medien
    Digitale Medien
    Dual capillary gas chromatographic analysis of alcohols and methyl tert-butyl ether in gasolines (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 383-387 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography, GC ; Dual capillary gas chromatography ; Alcohols ; MTBE ; Gasolines ; Additives ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: A gas chromatographic method has been developed for the identification and direct determination of alcohols and methyl tert-butyl ether (MTBE) in gasolines. The technique involves simultaneous injection of the gasoline without any sample preparation onto two fused silica capillary columns of differing polarities. The method permits simultaneous determinations of methanol, ethanol, 2-propanol, tert-butanol, 1-propanol, sec-butanol, 1-butanol, and MTBE. By using an automatic sampler in combination with electronic pressure programming and BASIC programming, the determinations were performed automatically and reproducibly with a relatively short analysis time.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090703
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  • 92
    Digitale Medien
    Digitale Medien
    “Donor-acceptor” complex chromatographic separation of explosives on 3-[9′-(10′-methylanthryl)]propylsilane stationary phase by HPLC (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 409-410 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, HPLC ; Reversed phase ; MAPS phase ; Explosives ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090710
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  • 93
    Digitale Medien
    Digitale Medien
    HPLC with electron-acceptor groups bonded to mercaptopropyl silica (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 417-419 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, HPLC ; Normal phase ; Bonded phases ; Mercaptopropyl silica gels ; Donor-acceptor complexes ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090714
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  • 94
    Digitale Medien
    Digitale Medien
    Selective quantification of ambroxol in human plasma by HPLC (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 561-565 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, HPLC ; Pharmacokinetics ; Quantification in human plasma ; Bronchosecretolyticum ; Separation from metabolites ; Ambroxol ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: The bronchosecretolytic drug ambroxol can be reliably quantified in human plasma by high performance liquid chromatography. Plasma is buffered alkaline, extracted with ether, and the organic solvent back-extracted with diluted acid. An automatically sampled aliquot is separated by reversed phase HPLC; the analyte is well separated from two metabolites that interfered strongly in earlier methods. UV detection at 230 nm enables a lower limit of quantitation of 5 ng/ml. Internal standardization with propranolol allows accurate and precise quantification. Evaluation of the optimized combination of mobile and stationary phase is described, and application of the method to experimental and clinical pharmacokinetic studies is illustrated.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240091004
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  • 95
    Digitale Medien
    Digitale Medien
    Measurement of sub parts-per million of inorganic anions in water by nonsuppressed ion exchange chromatography with conventional HPLC instrumentation (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 122-124 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, HPLC ; Nonsuppressed ion exchange ; Conductivity ; Detectability ; Inorganic anions ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090215
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  • 96
    Digitale Medien
    Digitale Medien
    Reversed-phase high performance liquid chromatography of 8-hydroxyquinoline complexes of Mo(VI), AI (III), CO(III), and Cu(II) (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 127-128 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography, HPLC ; Reversed-phase HPLC ; Metal chelates ; 8-Hydroxyquinolinates ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090217
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  • 97
    Digitale Medien
    Digitale Medien
    A simple high temperature, high pressure safe T-piece for installing micro packed glass columns as well as macrobore capillaries in a GC instrument (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 595-595 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography ; Connection device ; Micro packed columns ; Macrobore capillaries ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240091012
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  • 98
    Digitale Medien
    Digitale Medien
    Centrifugal planar-column chromatography (CPCC): A new preparative planar technique. Part 1: Description of the method and practical aspects (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 605-606 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Preparative planar chromatography, PPC ; Centrifugal planar-column chromatography, CPCC ; Circular development ; On-line observation and detection ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240091017
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  • 99
    Digitale Medien
    Digitale Medien
    Fused silica capillary tube isotachophoresis using a multichannel photodiode array detector (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 613-617 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Fused silica capillary tube isotachophoresis ; Multichannel photodiode array detector ; Cationic dye analysis ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Isotachophoresis carried out in a 0.25 mm i.d. fused-silica capillary tube yielded high resolution, compared with that in a fluorinated ethylene-propylene polymer tube. The use of an ultraviolet-visible multichannel spectrophotometer with photodiode array as detector together with a cross flow cell (volume 0.01 μl) was investigated. The system was successfully applied to the analysis of cationic dyes such as neutral red, bismarck brown, and basic fuchsine.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240091103
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  • 100
    Digitale Medien
    Digitale Medien
    A study of packed fused silica reverse-phase capillary columns (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 535-537 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Liquid chromatography ; Fused silica capillary columns ; Reverse-phase ; Nanoliter flow cell ; Column packing ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240090912
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